TreeWAS – Variant ID: rs1382269

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.122	0.878	0.000
M23.8 Other internal derangements of knee	0.072	0.928	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.063	0.937	0.000
G80.9 Infantile cerebral palsy, unspecified	0.060	0.940	0.000
G80 Infantile cerebral palsy	0.058	0.942	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.058	0.942	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.056	0.944	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.052	0.948	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.052	0.948	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.051	0.949	0.000
G80.0 Spastic cerebral palsy	0.051	0.949	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.050	0.950	0.000
G82.1 Spastic paraplegia	0.050	0.950	0.000
G83 Other paralytic syndromes	0.049	0.951	0.000
G82 Paraplegia and tetraplegia	0.048	0.952	0.000
G80.1 Spastic diplegia	0.047	0.953	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.045	0.955	0.000
G80.8 Other infantile cerebral palsy	0.045	0.955	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.044	0.956	0.000
G83.8 Other specified paralytic syndromes	0.044	0.956	0.000
G83.1 Monoplegia of lower limb	0.043	0.957	0.000
G80.4 Ataxic cerebral palsy	0.042	0.958	0.000
G80.3 Dyskinetic cerebral palsy	0.042	0.958	0.000
G83.2 Monoplegia of upper limb	0.041	0.959	0.000
G80.2 Infantile hemiplegia	0.040	0.960	0.000
Z00.0 General medical examination	0.035	0.965	0.000
G83.5 Locked-in syndrome	0.035	0.965	0.000
G83.3 Monoplegia, unspecified	0.035	0.965	0.000
G83.0 Diplegia of upper limbs	0.035	0.965	0.000
G82.4 Spastic tetraplegia	0.035	0.965	0.000
G82.3 Flaccid tetraplegia	0.035	0.965	0.000
G82.0 Flaccid paraplegia	0.035	0.965	0.000
G81 Hemiplegia	0.033	0.967	0.000
G83.4 Cauda equina syndrome	0.032	0.968	0.000
G83.9 Paralytic syndrome, unspecified	0.031	0.969	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.027	0.973	0.000
G82.5 Tetraplegia, unspecified	0.026	0.974	0.000
G81.1 Spastic hemiplegia	0.025	0.975	0.000
G82.2 Paraplegia, unspecified	0.024	0.975	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.024	0.976	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.976	0.024
G81.0 Flaccid hemiplegia	0.024	0.976	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.022	0.978	0.000
Z00.8 Other general examinations	0.021	0.979	0.000
Z00.5 Examination of potential donor of organ and tissue	0.020	0.980	0.000
F31 Bipolar affective disorder	0.020	0.980	0.000
F31.9 Bipolar affective disorder, unspecified	0.020	0.980	0.000
Z00.3 Examination for adolescent development state	0.020	0.980	0.000
Z00.2 Examination for period of rapid growth in childhood	0.020	0.980	0.000
Z00.1 Routine child health examination	0.020	0.980	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.019	0.981	0.000
G81.9 Hemiplegia, unspecified	0.018	0.982	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.016	0.984	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.016	0.984	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.016	0.984	0.000
F31.8 Other bipolar affective disorders	0.016	0.984	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.015	0.985	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.015	0.985	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.015	0.985	0.000
F31.7 Bipolar affective disorder, currently in remission	0.014	0.986	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.014	0.986	0.000
F30-F39 Mood [affective] disorders	0.014	0.986	0.000
F33 Recurrent depressive disorder	0.013	0.987	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.987	0.013
F39 Unspecified mood [affective] disorder	0.011	0.989	0.000
F38 Other mood [affective] disorders	0.011	0.989	0.000
F33.9 Recurrent depressive disorder, unspecified	0.011	0.989	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.011	0.989	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.011	0.989	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.010	0.990	0.000
F30 Manic episode	0.010	0.990	0.000
F38.8 Other specified mood [affective] disorders	0.010	0.990	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.009	0.990	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.990	0.010
R80 Isolated proteinuria	0.000	0.991	0.009
F34 Persistent mood [affective] disorders	0.009	0.991	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.009	0.991	0.000
F33.8 Other recurrent depressive disorders	0.009	0.991	0.000
F30.2 Mania with psychotic symptoms	0.009	0.991	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.992	0.008
F38.1 Other recurrent mood [affective] disorders	0.008	0.992	0.000
F38.0 Other single mood [affective] disorders	0.008	0.992	0.000
F30.1 Mania without psychotic symptoms	0.008	0.992	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.992	0.008
F30.8 Other manic episodes	0.007	0.992	0.000
R82 Other abnormal findings in urine	0.000	0.992	0.008
F30.0 Hypomania	0.007	0.993	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.993	0.007
R81 Glycosuria	0.000	0.993	0.007
F34.9 Persistent mood [affective] disorder, unspecified	0.006	0.993	0.000
F34.8 Other persistent mood [affective] disorders	0.006	0.993	0.000
F34.0 Cyclothymia	0.006	0.993	0.000
F30.9 Manic episode, unspecified	0.007	0.993	0.000
R59 Enlarged lymph nodes	0.000	0.993	0.007
R82.1 Myoglobinuria	0.000	0.993	0.007
S92.30 Fracture of metatarsal bone (closed)	0.000	0.993	0.007
R82.9 Other and unspecified abnormal finding in urine	0.000	0.994	0.006
R27.0 Ataxia, unspecified	0.006	0.994	0.000
R82.4 Acetonuria	0.000	0.994	0.006
D13.1 Stomach	0.006	0.994	0.000
F34.1 Dysthymia	0.005	0.994	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.994	0.006
R82.3 Haemoglobinuria	0.000	0.994	0.006
R82.2 Biliuria	0.000	0.994	0.006
R82.0 Chyluria	0.000	0.994	0.006
E16 Other disorders of pancreatic internal secretion	0.000	0.995	0.005
R59.9 Enlarged lymph nodes, unspecified	0.000	0.995	0.005
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
R27.8 Other and unspecified lack of coordination	0.005	0.995	0.000
R27 Other lack of coordination	0.005	0.995	0.000
S92.3 Fracture of metatarsal bone	0.000	0.995	0.005
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.005	0.995	0.000
M23 Internal derangement of knee	0.005	0.995	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.996	0.004
C15.5 Lower third of oesophagus	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
C67.2 Lateral wall of bladder	0.004	0.996	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.004	0.996	0.000
M23.5 Chronic instability of knee	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.996	0.004
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.996	0.004
E16.4 Abnormal secretion of gastrin	0.000	0.996	0.004
E16.3 Increased secretion of glucagon	0.000	0.996	0.004
M23.4 Loose body in knee	0.004	0.996	0.000
M23.1 Discoid meniscus (congenital)	0.004	0.996	0.000
C67.5 Bladder neck	0.004	0.996	0.000
K62.7 Radiation proctitis	0.000	0.996	0.004
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.996	0.004
C67.4 Posterior wall of bladder	0.004	0.996	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.996	0.004
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.004	0.996	0.000
M23.0 Cystic meniscus	0.004	0.996	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.004	0.996	0.000
S92 Fracture of foot, except ankle	0.000	0.996	0.004
C67.8 Overlapping lesion of bladder	0.004	0.996	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.000	0.996	0.004
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
M23.43 Loose body in knee-Med lig/oth men	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.000	0.996	0.004
S92.70 Multiple fractures of foot (closed)	0.000	0.996	0.004
C67.6 Ureteric orifice	0.004	0.996	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.996	0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.000	0.996	0.004
S92.0 Fracture of calcaneus	0.000	0.996	0.003
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.003	0.997	0.000
C67.1 Dome of bladder	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.003	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.003	0.997	0.000
M23.40 Loose body in knee-Mult sites	0.003	0.997	0.000
F32 Depressive episode	0.003	0.997	0.000
C67.7 Urachus	0.003	0.997	0.000
S92.4 Fracture of great toe	0.000	0.997	0.003
M23.46 Loose body in knee-O/unsp lat men	0.003	0.997	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.003	0.997	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.003	0.997	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
C82.2 Large cell, follicular	0.003	0.997	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.003	0.997	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.003	0.997	0.000
M23.47 Loose body in knee-Capsular lig	0.003	0.997	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.003	0.997	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
K75.0 Abscess of liver	0.000	0.997	0.003
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.003	0.997	0.000
S92.5 Fracture of other toe	0.000	0.997	0.003
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.997	0.003
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
M23.07 Cystic meniscus-Capsular lig	0.003	0.997	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.00 Cystic meniscus (Multiple sites)	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
D13.7 Endocrine pancreas	0.003	0.997	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.000	0.997	0.003
C15.3 Upper third of oesophagus	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.997	0.003
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.997	0.003
I99 Other and unspecified disorders of circulatory system	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.997	0.003
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.003	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
C82.0 Small cleaved cell, follicular	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.997	0.000
S92.51 Fracture of other toe (open)	0.000	0.997	0.003
D13.2 Duodenum	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.997	0.003
K29.3 Chronic superficial gastritis	0.000	0.997	0.003
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
E03.9 Hypothyroidism, unspecified	0.003	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
C71.1 Frontal lobe	0.000	0.997	0.003
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
F32.8 Other depressive episodes	0.003	0.997	0.000
C82.4 Follicular lymphoma grade IIIb	0.003	0.997	0.000
R25.2 Cramp and spasm	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.997	0.002
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.002	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.997	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.997	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.997	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.002	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.002
S92.1 Fracture of talus	0.000	0.997	0.002
Y40.3 Macrolides	0.002	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.002	0.997	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
C43.4 Malignant melanoma of scalp and neck	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
D13.0 Oesophagus	0.002	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.002	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.002	0.998	0.000
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.002	0.998	0.000
D13.6 Pancreas	0.002	0.998	0.000
D13.3 Other and unspecified parts of small intestine	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.998	0.002
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.002
C68.9 Urinary organ, unspecified	0.002	0.998	0.000
C68.0 Urethra	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.000	0.998	0.002
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.002
D13.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.002	0.998	0.000
C68.1 Paraurethral glands	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Z87.8 Personal history of other specified conditions	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.000	0.998	0.002
L29.2 Pruritus vulvae	0.000	0.998	0.002
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
D13.4 Liver	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.002
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.998	0.002
K26.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.002	0.998	0.000
D13.5 Extrahepatic bile ducts	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
M65 Synovitis and tenosynovitis	0.000	0.998	0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.998	0.002
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
C41.0 Bones of skull and face	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
J30.3 Other allergic rhinitis	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.998	0.002
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.998	0.002
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.998	0.002
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.998	0.002
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.998	0.002
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.998	0.002
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.998	0.002
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.998	0.002
M65.3 Trigger finger	0.000	0.998	0.002
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M65.1 Other infective (teno)synovitis	0.000	0.998	0.002
M65.34 Trigger finger-Hand	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
F32.0 Mild depressive episode	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.002
C21.0 Anus, unspecified	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
M65.2 Calcific tendinitis	0.000	0.998	0.002
M65.0 Abscess of tendon sheath	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations