TreeWAS – Variant ID: rs138904061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.656	0.344	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.643	0.357	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.633	0.367	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.621	0.379	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.611	0.389	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.592	0.408	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.587	0.413	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.579	0.421	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.574	0.426	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.563	0.437	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.560	0.440	0.000
T39.1 4-Aminophenol derivatives	0.558	0.442	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.546	0.454	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.526	0.474	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.520	0.480	0.000
T42.4 Benzodiazepines	0.512	0.488	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.512	0.488	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.492	0.508	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.491	0.509	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.489	0.511	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.478	0.522	0.000
T38.1 Thyroid hormones and substitutes	0.477	0.523	0.000
T40.2 Other opioids	0.471	0.529	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.470	0.530	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.470	0.530	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.470	0.530	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.463	0.537	0.000
T40.6 Other and unspecified narcotics	0.463	0.537	0.000
T38.9 Other and unspecified hormone antagonists	0.461	0.539	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.461	0.539	0.000
T38.7 Androgens and anabolic congeners	0.461	0.539	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.461	0.539	0.000
T38.5 Other oestrogens and progestogens	0.461	0.539	0.000
T38.4 Oral contraceptives	0.461	0.539	0.000
T38.2 Antithyroid drugs	0.461	0.539	0.000
T38.0 Glucocorticoids and synthetic analogues	0.461	0.539	0.000
T47.0 Histamine H(2)-receptor antagonists	0.457	0.543	0.000
T50.8 Diagnostic agents	0.446	0.554	0.000
T50.7 Analeptics and opioid receptor antagonists	0.446	0.554	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.446	0.554	0.000
T50.5 Appetite depressants	0.446	0.554	0.000
T50.4 Drugs affecting uric acid metabolism	0.446	0.554	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.446	0.554	0.000
T50.1 Loop [high-ceiling] diuretics	0.446	0.554	0.000
T50.0 Mineralocorticoids and their antagonists	0.446	0.554	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.439	0.561	0.000
T36 Poisoning by systemic antibiotics	0.439	0.561	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.438	0.562	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.438	0.562	0.000
T42.3 Barbiturates	0.438	0.562	0.000
T42.2 Succinimides and oxazolidinediones	0.438	0.562	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.428	0.572	0.000
T45.0 Antiallergic and antiemetic drugs	0.426	0.574	0.000
T39.0 Salicylates	0.424	0.576	0.000
T39.4 Antirheumatics, not elsewhere classified	0.421	0.579	0.000
T39.2 Pyrazolone derivatives	0.421	0.579	0.000
T45.2 Vitamins, not elsewhere classified	0.419	0.581	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.417	0.583	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.415	0.585	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.415	0.585	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.415	0.585	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.415	0.585	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.415	0.585	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.415	0.585	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.415	0.585	0.000
T44.0 Anticholinesterase agents	0.415	0.585	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.411	0.588	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.411	0.588	0.000
T47.7 Emetics	0.411	0.588	0.000
T47.6 Antidiarrhoeal drugs	0.411	0.588	0.000
T47.5 Digestants	0.411	0.588	0.000
T47.4 Other laxatives	0.411	0.588	0.000
T47.3 Saline and osmotic laxatives	0.411	0.588	0.000
T47.2 Stimulant laxatives	0.411	0.588	0.000
T43.6 Psychostimulants with abuse potential	0.408	0.592	0.000
T42.0 Hydantoin derivatives	0.403	0.597	0.000
T43.9 Psychotropic drug, unspecified	0.401	0.599	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.401	0.599	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.401	0.599	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.392	0.608	0.000
T40.8 Lysergide [LSD]	0.392	0.608	0.000
T40.7 Cannabis (derivatives)	0.392	0.608	0.000
T40.5 Cocaine	0.392	0.608	0.000
T40.3 Methadone	0.392	0.608	0.000
T40.1 Heroin	0.392	0.608	0.000
T40.0 Opium	0.392	0.608	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.383	0.617	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.379	0.621	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.377	0.623	0.000
T45.8 Other primarily systemic and haematological agents	0.377	0.623	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.377	0.623	0.000
T45.6 Fibrinolysis-affecting drugs	0.377	0.623	0.000
T45.4 Iron and its compounds	0.377	0.623	0.000
T45.3 Enzymes, not elsewhere classified	0.377	0.623	0.000
T42.1 Iminostilbenes	0.375	0.625	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.370	0.630	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.366	0.633	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.361	0.639	0.000
T43.2 Other and unspecified antidepressants	0.355	0.645	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.351	0.649	0.000
T37.5 Antiviral drugs	0.351	0.649	0.000
T37.4 Anthelminthics	0.351	0.649	0.000
T37.3 Other antiprotozoal drugs	0.351	0.649	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.351	0.649	0.000
T37.1 Antimycobacterial drugs	0.351	0.649	0.000
T37.0 Sulphonamides	0.351	0.649	0.000
T41.5 Therapeutic gases	0.337	0.663	0.000
T41.4 Anaesthetic, unspecified	0.337	0.663	0.000
T41.3 Local anaesthetics	0.337	0.663	0.000
T41.2 Other and unspecified general anaesthetics	0.337	0.663	0.000
T41.1 Intravenous anaesthetics	0.337	0.663	0.000
T41.0 Inhaled anaesthetics	0.337	0.663	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.337	0.663	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.337	0.663	0.000
T48.5 Anti-common-cold drugs	0.337	0.663	0.000
T48.4 Expectorants	0.337	0.663	0.000
T48.3 Antitussives	0.337	0.663	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.337	0.663	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.337	0.663	0.000
T48.0 Oxytocic drugs	0.337	0.663	0.000
T49.9 Topical agent, unspecified	0.337	0.663	0.000
T49.8 Other topical agents	0.337	0.663	0.000
T49.7 Dental drugs, topically applied	0.337	0.663	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.337	0.663	0.000
T49.5 Ophthalmological drugs and preparations	0.337	0.663	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.337	0.663	0.000
T49.3 Emollients, demulcents and protectants	0.337	0.663	0.000
T49.2 Local astringents and local detergents	0.337	0.663	0.000
T49.1 Antipruritics	0.337	0.663	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.337	0.663	0.000
T45.5 Anticoagulants	0.331	0.669	0.000
T36.9 Systemic antibiotic, unspecified	0.315	0.685	0.000
T36.8 Other systemic antibiotics	0.315	0.685	0.000
T36.7 Antifungal antibiotics, systemically used	0.315	0.685	0.000
T36.6 Rifamycins	0.315	0.685	0.000
T36.5 Aminoglycosides	0.315	0.685	0.000
T36.4 Tetracyclines	0.315	0.685	0.000
T36.3 Macrolides	0.315	0.685	0.000
T36.2 Chloramphenicol group	0.315	0.685	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.315	0.685	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.303	0.696	0.000
T46.1 Calcium-channel blockers	0.300	0.699	0.000
T36.0 Penicillins	0.283	0.717	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.275	0.725	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.275	0.725	0.000
T46.7 Peripheral vasodilators	0.275	0.725	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.275	0.725	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.275	0.725	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.273	0.726	0.000
T40.4 Other synthetic narcotics	0.245	0.754	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.215	0.785	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.195	0.804	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.184	0.816	0.001
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.884	0.116
I83 Varicose veins of lower extremities	0.000	0.901	0.099
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.908	0.092
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.914	0.086
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.930	0.070
K13.0 Diseases of lips	0.008	0.992	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.993	0.007
H26.8 Other specified cataract	0.000	0.993	0.007
I12.0 Hypertensive renal disease with renal failure	0.007	0.993	0.000
K65.9 Peritonitis, unspecified	0.000	0.995	0.005
N85.4 Malposition of uterus	0.000	0.995	0.005
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.995	0.005
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.996	0.004
C54.1 Endometrium	0.000	0.996	0.004
I51.9 Heart disease, unspecified	0.000	0.996	0.004
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.004
K65 Peritonitis	0.000	0.996	0.004
N35.9 Urethral stricture, unspecified	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.996	0.004
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.996	0.004
K65.0 Acute peritonitis	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.000	0.996	0.004
R22.0 Localised swelling, mass and lump, head	0.000	0.997	0.003
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.000	0.997	0.003
L81.4 Other melanin hyperpigmentation	0.003	0.997	0.000
T17.2 Foreign body in pharynx	0.003	0.997	0.000
K65.8 Other peritonitis	0.000	0.997	0.003
R25.2 Cramp and spasm	0.000	0.997	0.003
L57.0 Actinic keratosis	0.003	0.997	0.000
R54 Senility	0.003	0.997	0.000
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
J98.1 Pulmonary collapse	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
I12 Hypertensive renal disease	0.003	0.997	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.003
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
I47.2 Ventricular tachycardia	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.000	0.997	0.002
S92.4 Fracture of great toe	0.000	0.997	0.003
I51.4 Myocarditis, unspecified	0.000	0.997	0.003
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.002
S92.5 Fracture of other toe	0.000	0.997	0.002
S92.1 Fracture of talus	0.000	0.997	0.002
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.002
R16.1 Splenomegaly, not elsewhere classified	0.002	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
K76.6 Portal hypertension	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.002
N64.1 Fat necrosis of breast	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.002
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.002
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
C54 Malignant neoplasm of corpus uteri	0.000	0.998	0.002
M34 Systemic sclerosis	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.000	0.998	0.002
D24 Benign neoplasm of breast	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
T17 Foreign body in respiratory tract	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
R25 Abnormal involuntary movements	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
S92.51 Fracture of other toe (open)	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.002
K13 Other diseases of lip and oral mucosa	0.002	0.998	0.000
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
N35 Urethral stricture	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
C54.9 Corpus uteri, unspecified	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.002	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.998	0.002
C54.8 Overlapping lesion of corpus uteri	0.000	0.998	0.002
C54.3 Fundus uteri	0.000	0.998	0.002
C54.2 Myometrium	0.000	0.998	0.002
C54.0 Isthmus uteri	0.000	0.998	0.002
K13.6 Irritative hyperplasia of oral mucosa	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
T17.4 Foreign body in trachea	0.002	0.998	0.000
T17.3 Foreign body in larynx	0.002	0.998	0.000
T17.1 Foreign body in nostril	0.002	0.998	0.000
T17.0 Foreign body in nasal sinus	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
K13.5 Oral submucous fibrosis	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
F11.2 Dependence syndrome	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
Z74.9 Problem related to care-provider dependency, unspecified	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.000	0.998	0.001
S97.0 Crushing injury of ankle	0.000	0.998	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
N35.8 Other urethral stricture	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.002
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
L81 Other disorders of pigmentation	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
L81.0 Postinflammatory hyperpigmentation	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.002	0.998	0.000
K13.3 Hairy leukoplakia	0.002	0.998	0.000
K13.1 Cheek and lip biting	0.002	0.998	0.000
L81.8 Other specified disorders of pigmentation	0.002	0.998	0.000
Z74.0 Reduced mobility	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
K62.0 Anal polyp	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.001
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.001
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.002	0.998	0.000
K22.2 Oesophageal obstruction	0.000	0.998	0.002
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
N35.1 Postinfective urethral stricture, not elsewhere classified	0.001	0.998	0.000
N35.0 Posttraumatic urethral stricture	0.001	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.000
D81 Combined immunodeficiencies	0.001	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
N27.1 Small kidney, bilateral	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.998	0.000
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.001
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.001
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.001
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.001
Z03.5 Observation for other suspected cardiovascular diseases	0.002	0.998	0.000
K65-K67 Diseases of peritoneum	0.000	0.998	0.002
D84.1 Defects in the complement system	0.001	0.998	0.000
L81.7 Pigmented purpuric dermatosis	0.001	0.998	0.000
L81.6 Other disorders of diminished melanin formation	0.001	0.998	0.000
L81.5 Leukoderma, not elsewhere classified	0.001	0.998	0.000
L81.3 Cafe au lait spots	0.001	0.998	0.000
L81.1 Chloasma	0.001	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.001
K72.9 Hepatic failure, unspecified	0.000	0.998	0.001
R47.1 Dysarthria and anarthria	0.000	0.998	0.001
K13.29 Other disturbances of oral epithelium, including tongue	0.001	0.999	0.000
J98.8 Other specified respiratory disorders	0.001	0.999	0.000
J99.0 Rheumatoid lung disease	0.001	0.999	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.999	0.001
F12.1 Harmful use	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
I51.6 Cardiovascular disease, unspecified	0.001	0.999	0.001
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
H35.4 Peripheral retinal degeneration	0.000	0.999	0.001
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.999	0.001
Z74.8 Other problems related to care-provider dependency	0.001	0.999	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.999	0.001
C78.2 Secondary malignant neoplasm of pleura	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.999	0.001
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.999	0.001
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.999	0.001
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.999	0.001
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.999	0.001
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.999	0.001
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.999	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
F12.2 Dependence syndrome	0.001	0.999	0.000
F19.2 Dependence syndrome	0.001	0.999	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.001	0.999	0.000
S62.7 Multiple fractures of fingers	0.001	0.999	0.000
Z74.3 Need for continuous supervision	0.001	0.999	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.999	0.001
H43.8 Other disorders of vitreous body	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
L29.0 Pruritus ani	0.001	0.999	0.000
L81.9 Disorder of pigmentation, unspecified	0.001	0.999	0.000
S20.2 Contusion of thorax	0.000	0.999	0.001
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.999	0.001
F11.0 Acute intoxication	0.001	0.999	0.000
L81.2 Freckles	0.001	0.999	0.000
N64.8 Other specified disorders of breast	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
K38.1 Appendicular concretions	0.001	0.999	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.999	0.001
F11 Mental and behavioural disorders due to use of opioids	0.001	0.999	0.000
S20 Superficial injury of thorax	0.000	0.999	0.001
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.999	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.999	0.001
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.999	0.001
K82.8 Other specified diseases of gallbladder	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.000	0.999	0.001
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.999	0.001
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.999	0.001
K67.3 Tuberculous peritonitis	0.000	0.999	0.001
K67.2 Syphilitic peritonitis	0.000	0.999	0.001
K67.1 Gonococcal peritonitis	0.000	0.999	0.001
K67.0 Chlamydial peritonitis	0.000	0.999	0.001
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.999	0.001
N20.9 Urinary calculus, unspecified	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
E07.8 Other specified disorders of thyroid	0.001	0.999	0.000
F11.1 Harmful use	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.001	0.999	0.000
F11.9 Unspecified mental and behavioural disorder	0.001	0.999	0.000
F11.8 Other mental and behavioural disorders	0.001	0.999	0.000
F11.7 Residual and late-onset psychotic disorder	0.001	0.999	0.000
F11.6 Amnesic syndrome	0.001	0.999	0.000
F11.5 Psychotic disorder	0.001	0.999	0.000
F11.4 Withdrawal state with delirium	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations