TreeWAS – Variant ID: rs1392502

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S42.00 Fracture of clavicle (closed)	0.134	0.866	0.000
S42.0 Fracture of clavicle	0.118	0.882	0.000
S42 Fracture of shoulder and upper arm	0.109	0.891	0.000
S42.2 Fracture of upper end of humerus	0.104	0.896	0.000
S42.20 Fracture of upper end of humerus (closed)	0.102	0.898	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.089	0.911	0.000
S42.3 Fracture of shaft of humerus	0.087	0.913	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.085	0.915	0.000
S42.01 Fracture of clavicle (open)	0.082	0.918	0.000
R19.5 Other fecal abnormalities	0.080	0.920	0.000
S42.4 Fracture of lower end of humerus	0.078	0.922	0.000
S42.1 Fracture of scapula	0.077	0.923	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.075	0.924	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.075	0.925	0.000
S42.30 Fracture of shaft of humerus (closed)	0.074	0.926	0.000
S42.21 Fracture of upper end of humerus (open)	0.069	0.930	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.067	0.933	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.064	0.936	0.000
S42.40 Fracture of lower end of humerus (closed)	0.062	0.938	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.061	0.939	0.000
S42.31 Fracture of shaft of humerus (open)	0.059	0.941	0.000
S42.11 Fracture of scapula (open)	0.055	0.944	0.000
S42.10 Fracture of scapula (closed)	0.054	0.946	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.054	0.946	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.051	0.948	0.000
S42.41 Fracture of lower end of humerus (open)	0.047	0.953	0.000
S40-S49 Injuries to the shoulder and upper arm	0.017	0.983	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.985	0.015
S44 Injury of nerves at shoulder and upper arm level	0.013	0.986	0.000
S48 Traumatic amputation of shoulder and upper arm	0.013	0.987	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.013	0.987	0.000
S47 Crushing injury of shoulder and upper arm	0.013	0.987	0.000
S40 Superficial injury of shoulder and upper arm	0.013	0.987	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.012	0.988	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.011	0.988	0.000
S44.2 Injury of radial nerve at upper arm level	0.011	0.989	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.010	0.990	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.010	0.990	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.010	0.990	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.010	0.990	0.000
S44.4 Injury of musculocutaneous nerve	0.010	0.990	0.000
S44.3 Injury of axillary nerve	0.010	0.990	0.000
S44.1 Injury of median nerve at upper arm level	0.010	0.990	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.010	0.990	0.000
S40.0 Contusion of shoulder and upper arm	0.010	0.990	0.000
S41 Open wound of shoulder and upper arm	0.010	0.990	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.009	0.991	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.009	0.991	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.009	0.991	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.009	0.991	0.000
S45.2 Injury of axillary or brachial vein	0.009	0.991	0.000
S45.1 Injury of brachial artery	0.009	0.991	0.000
S45.0 Injury of axillary artery	0.009	0.991	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.009	0.991	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.009	0.991	0.000
S48.0 Traumatic amputation at shoulder joint	0.009	0.991	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.009	0.991	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.009	0.991	0.000
S43.2 Dislocation of sternoclavicular joint	0.009	0.991	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.991	0.009
Q21.1 Atrial septal defect	0.009	0.991	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.009	0.991	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.009	0.991	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.009	0.991	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.009	0.991	0.000
S43.4 Sprain and strain of shoulder joint	0.008	0.991	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.008	0.991	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.008	0.991	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.008	0.992	0.000
D03.5 Melanoma in situ of trunk	0.008	0.992	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.008	0.992	0.000
S43.1 Dislocation of acromioclavicular joint	0.008	0.992	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.008	0.992	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.007	0.992	0.000
Q21 Congenital malformations of cardiac septa	0.008	0.992	0.000
S43.0 Dislocation of shoulder joint	0.007	0.993	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
D03 Melanoma in situ	0.007	0.993	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.007	0.993	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.007	0.993	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.007	0.993	0.000
D03.4 Melanoma in situ of scalp and neck	0.007	0.993	0.000
I60 Subarachnoid haemorrhage	0.007	0.993	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.006	0.994	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.006	0.994	0.000
Q24 Other congenital malformations of heart	0.006	0.994	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.006	0.994	0.000
D03.8 Melanoma in situ of other sites	0.006	0.994	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.006	0.994	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.006	0.994	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
S41.1 Open wound of upper arm	0.005	0.994	0.000
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
Q21.4 Aortopulmonary septal defect	0.006	0.994	0.000
Q21.3 Tetralogy of Fallot	0.006	0.994	0.000
Q21.2 Atrioventricular septal defect	0.006	0.994	0.000
D03.9 Melanoma in situ, unspecified	0.005	0.994	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.005	0.994	0.000
I60.8 Other subarachnoid haemorrhage	0.005	0.994	0.000
Q21.0 Ventricular septal defect	0.005	0.994	0.000
S41.0 Open wound of shoulder	0.005	0.994	0.001
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
S46.3 Injury of muscle and tendon of triceps	0.005	0.995	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.005	0.995	0.000
D03.0 Melanoma in situ of lip	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
M67 Other disorders of synovium and tendon	0.000	0.995	0.005
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.995	0.005
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.005	0.995	0.000
Q27 Other congenital malformations of peripheral vascular system	0.005	0.995	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.005	0.995	0.000
M77.4 Metatarsalgia	0.000	0.995	0.005
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.005	0.995	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O14.9 Preeclampsia, unspecified	0.000	0.995	0.005
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.000	0.995	0.005
Q22.1 Congenital pulmonary valve stenosis	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.995	0.005
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.005	0.995	0.000
Q24.6 Congenital heart block	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
O14.1 Severe preeclampsia	0.000	0.995	0.005
I60.4 Subarachnoid haemorrhage from basilar artery	0.004	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.000	0.995	0.005
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.995	0.004
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q27.3 Peripheral arteriovenous malformation	0.004	0.996	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
O15 Eclampsia	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.000	0.996	0.004
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.996	0.004
M67.3 Transient synovitis	0.000	0.996	0.004
O14.2 HELLP syndrome	0.000	0.996	0.004
Q27.4 Congenital phlebectasia	0.004	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.996	0.000
M67.0 Short Achilles tendon (acquired)	0.000	0.996	0.004
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
M77.49 Metatarsalgia-Site unspec	0.000	0.996	0.004
M77.48 Metatarsalgia-Other	0.000	0.996	0.004
M77.46 Metatarsalgia-Lower Leg	0.000	0.996	0.004
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.996	0.004
M77.44 Metatarsalgia-Hand	0.000	0.996	0.004
M77.43 Metatarsalgia-Forearm	0.000	0.996	0.004
M77.42 Metatarsalgia-Upper arm	0.000	0.996	0.004
M77.41 Metatarsalgia-Shldr region	0.000	0.996	0.004
M77.40 Metatarsalgia-Mult sites	0.000	0.996	0.004
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.996	0.004
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.004
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.996	0.004
Q25.1 Coarctation of aorta	0.003	0.996	0.000
M67.4 Ganglion	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.003
O15.1 Eclampsia in labour	0.000	0.997	0.003
O15.0 Eclampsia in pregnancy	0.000	0.997	0.003
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.997	0.003
O15.2 Eclampsia in the puerperium	0.000	0.997	0.003
D35.0 Adrenal gland	0.003	0.997	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.997	0.003
O12.0 Gestational oedema	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.997	0.003
Z73.3 Stress, not elsewhere classified	0.000	0.997	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
S00.0 Superficial injury of scalp	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
B37.9 Candidiasis, unspecified	0.003	0.997	0.000
S52.00 Fracture of upper end of ulna (closed)	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.000	0.997	0.002
M67.45 Ganglion, hip	0.000	0.997	0.002
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.997	0.000
L72.0 Epidermal cyst	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.997	0.000
M67.47 Ganglion, ankle and foot	0.000	0.997	0.002
I84.4 External haemorrhoids with other complications	0.000	0.997	0.003
O12.1 Gestational proteinuria	0.000	0.997	0.002
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.997	0.003
H53.4 Visual field defects	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Z03.3 Observation for suspected nervous system disorder	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.000	0.998	0.002
D25.2 Subserosal leiomyoma of uterus	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
M77.0 Medial epicondylitis	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
F52.2 Failure of genital response	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
M77 Other enthesopathies	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.000	0.998	0.002
M77.08 Medial epicondylitis-Other	0.000	0.998	0.002
M77.07 Medial epicondylitis-Ankle/Foot	0.000	0.998	0.002
M77.06 Medial epicondylitis (Lower leg)	0.000	0.998	0.002
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.000	0.998	0.002
M77.04 Medial epicondylitis-Hand	0.000	0.998	0.002
M77.03 Medial epicondylitis-Forearm	0.000	0.998	0.002
M77.01 Medial epicondylitis-Shldr region	0.000	0.998	0.002
M77.00 Medial epicondylitis (Multiple sites)	0.000	0.998	0.002
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.000	0.998	0.002
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.000	0.998	0.002
M77.2 Periarthritis of wrist	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.002
Q12 Congenital lens malformations	0.002	0.998	0.000
M77.3 Calcaneal spur	0.000	0.998	0.002
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.998	0.002
Q17.5 Prominent ear	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
J67.2 Bird fancier's lung	0.000	0.998	0.002
M40.2 Other and unspecified kyphosis	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
R50.8 Other specified fever	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.000	0.998	0.002
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M77.5 Other enthesopathy of foot	0.000	0.998	0.002
Q12.0 Congenital cataract	0.002	0.998	0.000
R19.6 Halitosis	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
M77.1 Lateral epicondylitis	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.001	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.001	0.998	0.000
Q17.4 Misplaced ear	0.001	0.998	0.000
Q17.3 Other misshapen ear	0.001	0.998	0.000
Q17.2 Microtia	0.001	0.998	0.000
Q17.1 Macrotia	0.001	0.998	0.000
Q17.0 Accessory auricle	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.001	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
K31.4 Gastric diverticulum	0.000	0.998	0.002
M77.9 Enthesopathy, unspecified	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
R50.0 Fever with chills	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.000	0.998	0.001
M77.29 Periarthritis of wrist-Site unspec	0.000	0.998	0.001
M77.28 Periarthritis of wrist-Other	0.000	0.998	0.001
M77.27 Periarthritis of wrist-Ankle/Foot	0.000	0.998	0.001
M77.26 Periarthritis of wrist-Lower Leg	0.000	0.998	0.001
M77.25 Periarthritis of wrist-Pelvic/Thigh	0.000	0.998	0.001
M77.24 Periarthritis of wrist-Hand	0.000	0.998	0.001
M77.23 Periarthritis of wrist-Forearm	0.000	0.998	0.001
M77.22 Periarthritis of wrist-Upper arm	0.000	0.998	0.001
M77.21 Periarthritis of wrist-Shldr region	0.000	0.998	0.001
M77.20 Periarthritis of wrist-Mult sites	0.000	0.998	0.001
M77.89 Other enthesopathies, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M77.88 Other enthesopathies, not elsewhere classified (Other)	0.000	0.998	0.001
M77.87 Other enthesopathies, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
M77.86 Other enthesopathies, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M77.85 Other enthesopathies, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
M77.84 Other enthesopathies, not elsewhere classified (Hand)	0.000	0.998	0.001
M77.83 Other enthesopathies, not elsewhere classified (Forearm)	0.000	0.998	0.001
M77.82 Other enthesopathies, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M77.81 Other enthesopathies, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
M77.80 Other enthesopathies, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
I47.2 Ventricular tachycardia	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
M77.13 Lateral epicondylitis-Forearm	0.000	0.998	0.001
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.000	0.998	0.001
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.001	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
M77.39 Calcaneal spur-Site unspec	0.000	0.998	0.001
M77.38 Calcaneal spur-Other	0.000	0.998	0.001
M77.36 Calcaneal spur-Lower Leg	0.000	0.998	0.001
M77.35 Calcaneal spur-Pelvic/Thigh	0.000	0.998	0.001
M77.34 Calcaneal spur-Hand	0.000	0.998	0.001
M77.33 Calcaneal spur-Forearm	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations