TreeWAS – Variant ID: rs1398217

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K05.3 Chronic periodontitis	0.000	0.981	0.019
J30.1 Allergic rhinitis due to pollen	0.017	0.983	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.985	0.015
J30 Vasomotor and allergic rhinitis	0.014	0.986	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.014	0.986	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.987	0.013
J30.3 Other allergic rhinitis	0.013	0.987	0.000
J30.4 Allergic rhinitis, unspecified	0.013	0.987	0.000
J30.2 Other seasonal allergic rhinitis	0.011	0.989	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.011	0.989	0.000
J30.0 Vasomotor rhinitis	0.010	0.990	0.000
R23.3 Spontaneous ecchymoses	0.000	0.990	0.010
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.990	0.010
D69 Purpura and other haemorrhagic conditions	0.009	0.991	0.000
D69.0 Allergic purpura	0.009	0.991	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.991	0.009
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.991	0.009
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.991	0.009
U89 Agent resistant to other and unspecified antibiotics	0.000	0.992	0.008
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.992	0.008
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.992	0.008
D69.5 Secondary thrombocytopenia	0.008	0.992	0.000
D69.2 Other nonthrombocytopenic purpura	0.007	0.992	0.000
D69.4 Other primary thrombocytopenia	0.007	0.993	0.000
R23 Other skin changes	0.000	0.993	0.007
D69.1 Qualitative platelet defects	0.007	0.993	0.000
K05 Gingivitis and periodontal diseases	0.000	0.993	0.007
J43.9 Emphysema, unspecified	0.000	0.993	0.007
Q28.2 Arteriovenous malformation of cerebral vessels	0.007	0.993	0.000
D69.9 Haemorrhagic condition, unspecified	0.007	0.993	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.993	0.007
U89.9 Agent resistant to unspecified antibiotic	0.000	0.993	0.007
N36.2 Urethral caruncle	0.000	0.993	0.007
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.993	0.007
R23.1 Pallor	0.000	0.993	0.007
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
O64.5 Obstructed labour due to compound presentation	0.000	0.994	0.006
O64.4 Obstructed labour due to shoulder presentation	0.000	0.994	0.006
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.994	0.006
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.994	0.006
R23.8 Other and unspecified skin changes	0.000	0.994	0.006
R23.2 Flushing	0.000	0.994	0.006
D69.8 Other specified haemorrhagic conditions	0.006	0.994	0.000
O64.2 Obstructed labour due to face presentation	0.000	0.994	0.006
O64.3 Obstructed labour due to brow presentation	0.000	0.994	0.006
K05.6 Periodontal disease, unspecified	0.000	0.994	0.006
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.994	0.006
Q28 Other congenital malformations of circulatory system	0.006	0.994	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.994	0.006
Z90.3 Acquired absence of part of stomach	0.000	0.994	0.006
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.994	0.006
K05.1 Chronic gingivitis	0.000	0.994	0.006
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.994	0.006
K05.2 Acute periodontitis	0.000	0.995	0.005
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.995	0.005
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
J43 Emphysema	0.000	0.995	0.005
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.995	0.005
J43.2 Centrilobular emphysema	0.000	0.995	0.005
Q28.0 Arteriovenous malformation of precerebral vessels	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.005	0.995	0.000
R23.0 Cyanosis	0.000	0.995	0.005
K05.5 Other periodontal diseases	0.000	0.995	0.005
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.995	0.005
K05.0 Acute gingivitis	0.000	0.995	0.005
K05.4 Periodontosis	0.000	0.995	0.005
R25.1 Tremor, unspecified	0.000	0.995	0.005
I34.1 Mitral (valve) prolapse	0.005	0.995	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.995	0.005
F41.1 Generalised anxiety disorder	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
J43.8 Other emphysema	0.000	0.995	0.005
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.995	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.995	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.995	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
D68.6 Other Thrombophilia	0.004	0.996	0.000
R23.4 Changes in skin texture	0.000	0.996	0.004
Q24 Other congenital malformations of heart	0.004	0.996	0.000
N13.6 Pyonephrosis	0.000	0.996	0.004
D66 Hereditary factor VIII deficiency	0.004	0.996	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.996	0.004
K05.22 Aggressive periodontitis, generalized	0.000	0.996	0.004
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
B95-B98 Bacterial, viral and other infectious agents	0.000	0.996	0.004
J43.1 Panlobular emphysema	0.000	0.996	0.004
J43.0 MacLeod's syndrome	0.000	0.996	0.004
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
Z98.0 Intestinal bypass and anastomosis status	0.000	0.996	0.004
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.996	0.004
D68.5 Primary Thrombophilia	0.004	0.996	0.000
A63.0 Anogenital (venereal) warts	0.004	0.996	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.996	0.004
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
N13.4 Hydroureter	0.000	0.996	0.004
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.003	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
N13 Obstructive and reflux uropathy	0.000	0.997	0.003
D68.9 Coagulation defect, unspecified	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.997	0.003
U83 Resistance to other antibiotics	0.000	0.997	0.003
U82 Resistance to betalactam antibiotics	0.000	0.997	0.003
U85 Resistance to antineoplastic drugs	0.000	0.997	0.003
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.997	0.003
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
N41.0 Acute prostatitis	0.003	0.997	0.000
R25.2 Cramp and spasm	0.000	0.997	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.003	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
Q25.1 Coarctation of aorta	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.997	0.002
N13.3 Other and unspecified hydronephrosis	0.000	0.997	0.003
S52.10 Fracture of upper end of radius (closed)	0.000	0.997	0.003
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.997	0.003
Z98.8 Other specified postsurgical states	0.000	0.997	0.003
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Z98 Other postsurgical states	0.000	0.997	0.003
Q65.6 Unstable hip	0.002	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.997	0.002
U82.8 Resistance to other betalactam antibiotics	0.000	0.997	0.002
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.997	0.002
U82.1 Resistance to methicillin	0.000	0.997	0.002
U82.0 Resistance to penicillin	0.000	0.997	0.002
U83.9 Resistance to unspecified antibiotic	0.000	0.997	0.002
U83.8 Resistance to other single specified antibiotic	0.000	0.997	0.002
U83.7 Resistance to multiple antibiotics	0.000	0.997	0.002
U83.2 Resistance to quinolones	0.000	0.997	0.002
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.997	0.002
U83.0 Resistance to vancomycin	0.000	0.997	0.002
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.997	0.002
U84.8 Resistance to other specified antimicrobial drug	0.000	0.997	0.002
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.997	0.002
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.997	0.002
U84.2 Resistance to antiviral drug(s)	0.000	0.997	0.002
U84.1 Resistance to antifungal drug(s)	0.000	0.997	0.002
U84.0 Resistance to antiparasitic drug(s)	0.000	0.997	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.997	0.000
Q25.2 Atresia of aorta	0.002	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.997	0.003
R25 Abnormal involuntary movements	0.000	0.997	0.003
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.997	0.000
Q22.0 Pulmonary valve atresia	0.002	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.997	0.000
D68.8 Other specified coagulation defects	0.002	0.997	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.000	0.998	0.002
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
R76.0 Raised antibody titer	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
A49.0 Staphylococcal infection, unspecified	0.000	0.998	0.002
Z98.1 Arthrodesis status	0.000	0.998	0.002
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
Q44.6 Cystic disease of liver	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
R25.0 Abnormal head movements	0.000	0.998	0.002
S59.9 Unspecified injury of forearm	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.002	0.998	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
R76.2 False-positive serological test for syphilis	0.000	0.998	0.002
R76.1 Abnormal reaction to tuberculin test	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.998	0.002
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.998	0.002
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q70 Syndactyly	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
C71.3 Parietal lobe	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.002
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
S05 Injury of eye and orbit	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.998	0.001
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.000	0.998	0.002
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
T80.6 Other serum reactions	0.000	0.998	0.002
T80.5 Anaphylactic shock due to serum	0.000	0.998	0.002
T80.4 Rh incompatibility reaction	0.000	0.998	0.002
T80.3 ABO incompatibility reaction	0.000	0.998	0.002
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.998	0.002
G30 Alzheimer's disease	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q80-Q89 Other congenital malformations	0.001	0.998	0.000
Q21.0 Ventricular septal defect	0.001	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.998	0.001
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
A60.0 Herpesviral infection of genitalia and urogenital tract	0.001	0.998	0.000
C18.9 Colon, unspecified	0.000	0.998	0.002
D04.0 Skin of lip	0.001	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.998	0.000
Q78.6 Multiple congenital exostoses	0.001	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.998	0.000
Q78.4 Enchondromatosis	0.001	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.998	0.000
R25.3 Fasciculation	0.000	0.998	0.001
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.998	0.000
C25.0 Head of pancreas	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.001
N60.2 Fibroadenosis of breast	0.000	0.998	0.002
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.001
N19 Unspecified renal failure	0.000	0.998	0.002
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
I82.2 Embolism and thrombosis of vena cava	0.001	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.001
Q07 Other congenital malformations of nervous system	0.001	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.001
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.998	0.000
S05.7 Avulsion of eye	0.000	0.998	0.001
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations