TreeWAS – Variant ID: rs1398942

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.189	0.811
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.557	0.443
C43 Malignant melanoma of skin	0.000	0.584	0.416
C43.4 Malignant melanoma of scalp and neck	0.000	0.595	0.405
C43.9 Malignant melanoma of skin, unspecified	0.000	0.605	0.395
C43.5 Malignant melanoma of trunk	0.000	0.638	0.362
C43.8 Overlapping malignant melanoma of skin	0.000	0.702	0.298
C43.0 Malignant melanoma of lip	0.000	0.702	0.298
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.719	0.280
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.743	0.257
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.752	0.247
N88 Other noninflammatory disorders of cervix uteri	0.000	0.809	0.191
N88.1 Old laceration of cervix uteri	0.000	0.847	0.153
N88.4 Hypertrophic elongation of cervix uteri	0.000	0.863	0.137
N88.0 Leukoplakia of cervix uteri	0.000	0.863	0.137
N88.3 Incompetence of cervix uteri	0.000	0.865	0.135
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.873	0.127
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.930	0.070
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.058	0.942	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.049	0.951	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.952	0.048
S40 Superficial injury of shoulder and upper arm	0.044	0.956	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.041	0.959	0.000
O42 Premature rupture of membranes	0.040	0.960	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.964	0.035
O42.9 Premature rupture of membranes, unspecified	0.035	0.965	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.034	0.966	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.967	0.033
S40.0 Contusion of shoulder and upper arm	0.032	0.968	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.032	0.968	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.028	0.972	0.000
S40-S49 Injuries to the shoulder and upper arm	0.026	0.974	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.026	0.974	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.025	0.975	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.022	0.978	0.000
S41 Open wound of shoulder and upper arm	0.020	0.980	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.020	0.980	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.020	0.980	0.000
S48 Traumatic amputation of shoulder and upper arm	0.019	0.981	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.019	0.981	0.000
S44 Injury of nerves at shoulder and upper arm level	0.019	0.981	0.000
S47 Crushing injury of shoulder and upper arm	0.019	0.981	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.019	0.981	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.019	0.981	0.000
S46.3 Injury of muscle and tendon of triceps	0.018	0.982	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.982	0.018
S32.10 Fracture of sacrum (closed)	0.000	0.982	0.018
S32.1 Fracture of sacrum	0.000	0.982	0.018
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.983	0.017
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.983	0.017
S32.5 Fracture of pubis	0.000	0.983	0.017
S32.50 Fracture of pubis (closed)	0.000	0.983	0.017
S49 Other and unspecified injuries of shoulder and upper arm	0.017	0.983	0.000
S41.1 Open wound of upper arm	0.016	0.984	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.016	0.984	0.000
K09.0 Developmental odontogenic cysts	0.016	0.984	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.984	0.016
S32.4 Fracture of acetabulum	0.000	0.985	0.015
J02 Acute pharyngitis	0.000	0.985	0.015
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.015	0.985	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.015	0.985	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.986	0.014
S41.0 Open wound of shoulder	0.014	0.986	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.014	0.986	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.014	0.986	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.014	0.986	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.014	0.986	0.000
S44.4 Injury of musculocutaneous nerve	0.014	0.986	0.000
S44.3 Injury of axillary nerve	0.014	0.986	0.000
S44.2 Injury of radial nerve at upper arm level	0.014	0.986	0.000
S44.1 Injury of median nerve at upper arm level	0.014	0.986	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.014	0.986	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.014	0.986	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.014	0.986	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.014	0.986	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.014	0.986	0.000
S45.2 Injury of axillary or brachial vein	0.014	0.986	0.000
S45.1 Injury of brachial artery	0.014	0.986	0.000
S45.0 Injury of axillary artery	0.014	0.986	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.014	0.986	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.014	0.986	0.000
S48.0 Traumatic amputation at shoulder joint	0.014	0.986	0.000
S42 Fracture of shoulder and upper arm	0.013	0.986	0.000
H18 Other disorders of cornea	0.014	0.986	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.987	0.013
S43.4 Sprain and strain of shoulder joint	0.013	0.987	0.000
H18.6 Keratoconus	0.013	0.987	0.000
H18.8 Other specified disorders of cornea	0.013	0.987	0.000
S32.2 Fracture of coccyx	0.000	0.987	0.013
S32.0 Fracture of lumbar vertebra	0.000	0.987	0.013
S32.11 Fracture of sacrum (open)	0.000	0.987	0.013
S32.3 Fracture of ilium	0.000	0.987	0.013
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.013	0.987	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.987	0.013
S32.51 Fracture of pubis (open)	0.000	0.987	0.012
S43.2 Dislocation of sternoclavicular joint	0.012	0.988	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.012	0.988	0.000
S42.2 Fracture of upper end of humerus	0.012	0.988	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.012	0.988	0.000
H18.1 Bullous keratopathy	0.012	0.988	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.012	0.988	0.000
J02.0 Streptococcal pharyngitis	0.000	0.988	0.012
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.988	0.012
H18.4 Corneal degeneration	0.012	0.988	0.000
H18.5 Hereditary corneal dystrophies	0.012	0.988	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.011	0.988	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.011	0.988	0.000
S43.1 Dislocation of acromioclavicular joint	0.012	0.988	0.000
S42.20 Fracture of upper end of humerus (closed)	0.011	0.989	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.011	0.989	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.989	0.011
H18.2 Other corneal oedema	0.011	0.989	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.989	0.010
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.990	0.010
H18.7 Other corneal deformities	0.010	0.990	0.000
H18.3 Changes in corneal membranes	0.010	0.990	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.010	0.990	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.009	0.990	0.000
S32.21 Fracture of coccyx (open)	0.000	0.990	0.009
S32.20 Fracture of coccyx (closed)	0.000	0.990	0.009
H18.0 Corneal pigmentations and deposits	0.010	0.990	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.990	0.009
S32.31 Fracture of ilium (open)	0.000	0.990	0.009
S42.8 Fracture of other parts of shoulder and upper arm	0.009	0.990	0.001
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.991	0.009
S32.30 Fracture of ilium (closed)	0.000	0.991	0.009
S42.21 Fracture of upper end of humerus (open)	0.009	0.991	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.009	0.991	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.008	0.991	0.001
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
H18.9 Disorder of cornea, unspecified	0.009	0.991	0.000
M45 Ankylosing spondylitis	0.000	0.992	0.008
S42.4 Fracture of lower end of humerus	0.007	0.992	0.001
Q28 Other congenital malformations of circulatory system	0.008	0.992	0.000
S42.3 Fracture of shaft of humerus	0.007	0.992	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.008	0.992	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.008	0.992	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.008	0.992	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.008	0.992	0.000
S42.1 Fracture of scapula	0.006	0.992	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.993	0.007
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.000	0.993	0.007
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.007	0.993	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.007	0.993	0.001
Q25 Congenital malformations of great arteries	0.007	0.993	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.007	0.993	0.000
Q23 Congenital malformations of aortic and mitral valves	0.007	0.993	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.993	0.007
Q24 Other congenital malformations of heart	0.007	0.993	0.000
S42.41 Fracture of lower end of humerus (open)	0.006	0.993	0.000
Q28.3 Other malformations of cerebral vessels	0.007	0.993	0.000
Q27 Other congenital malformations of peripheral vascular system	0.007	0.993	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.006	0.993	0.001
F60.9 Personality disorder, unspecified	0.007	0.993	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.006	0.993	0.001
S42.31 Fracture of shaft of humerus (open)	0.006	0.993	0.000
S42.0 Fracture of clavicle	0.006	0.994	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.994	0.006
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.994	0.006
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.994	0.006
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.994	0.006
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.994	0.006
G50.0 Trigeminal neuralgia	0.006	0.994	0.000
Q26 Congenital malformations of great veins	0.006	0.994	0.000
Q25.4 Other congenital malformations of aorta	0.006	0.994	0.000
Q23.0 Congenital stenosis of aortic valve	0.006	0.994	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.006	0.994	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.006	0.994	0.000
Q28.1 Other malformations of precerebral vessels	0.006	0.994	0.000
Q24.6 Congenital heart block	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.006	0.994	0.000
Q25.0 Patent ductus arteriosus	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.994	0.006
Q20 Congenital malformations of cardiac chambers and connexions	0.006	0.994	0.000
S42.11 Fracture of scapula (open)	0.004	0.994	0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.006	0.994	0.000
Q25.1 Coarctation of aorta	0.006	0.994	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.006	0.994	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
Z11.5 Special screening examination for other viral diseases	0.006	0.994	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.994	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.995	0.005
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.005	0.995	0.001
C67.2 Lateral wall of bladder	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
C67 Malignant neoplasm of bladder	0.005	0.995	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.005	0.995	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q23.4 Hypoplastic left heart syndrome	0.005	0.995	0.000
Q23.2 Congenital mitral stenosis	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.005	0.995	0.000
Q23.3 Congenital mitral insufficiency	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
Q27.4 Congenital phlebectasia	0.005	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
C67.0 Trigone of bladder	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
S42.01 Fracture of clavicle (open)	0.004	0.995	0.000
D25.1 Intramural leiomyoma of uterus	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.005	0.995	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.005	0.995	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.005	0.995	0.000
Q26.8 Other congenital malformations of great veins	0.005	0.995	0.000
Q26.6 Portal vein-hepatic artery fistula	0.005	0.995	0.000
Q26.5 Anomalous portal venous connexion	0.005	0.995	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.1 Persistent left superior vena cava	0.005	0.995	0.000
Q26.0 Congenital stenosis of vena cava	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.005	0.995	0.000
Q25.3 Stenosis of aorta	0.004	0.995	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.005	0.995	0.000
C67.4 Posterior wall of bladder	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.995	0.000
T45.4 Iron and its compounds	0.004	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.995	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.004	0.996	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.996	0.004
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.996	0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
C67.3 Anterior wall of bladder	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
C67.1 Dome of bladder	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
F60 Specific personality disorders	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
F60.3 Emotionally unstable personality disorder	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
C67.7 Urachus	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
Q38.1 Ankyloglossia	0.004	0.996	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.001	0.996	0.003
Q43.3 Congenital malformations of intestinal fixation	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Q39.4 Oesophageal web	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
R23.8 Other and unspecified skin changes	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
F60.2 Dissocial personality disorder	0.004	0.996	0.000
H83.0 Labyrinthitis	0.004	0.996	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.996	0.004
T40.5 Cocaine	0.003	0.996	0.000
H50.1 Divergent concomitant strabismus	0.000	0.996	0.004
T40.3 Methadone	0.003	0.996	0.000
Q38.7 Pharyngeal pouch	0.003	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.996	0.000
Q04.6 Congenital cerebral cysts	0.003	0.996	0.000
T36.3 Macrolides	0.003	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.996	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.996	0.003
T36.4 Tetracyclines	0.003	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.996	0.000
T40.8 Lysergide [LSD]	0.003	0.996	0.000
T40.7 Cannabis (derivatives)	0.003	0.996	0.000
T40.1 Heroin	0.003	0.996	0.000
T40.0 Opium	0.003	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.996	0.000
Q04 Other congenital malformations of brain	0.003	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
L82 Seborrhoeic keratosis	0.000	0.997	0.003
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Z01.4 Gynaecological examination (general)(routine)	0.003	0.997	0.000
F60.8 Other specific personality disorders	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
F60.0 Paranoid personality disorder	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.003	0.997	0.000
F60.1 Schizoid personality disorder	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
C16.0 Cardia	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
H11.3 Conjunctival haemorrhage	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
H50.5 Heterophoria	0.000	0.997	0.003
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
C67.6 Ureteric orifice	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.002	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations