TreeWAS – Variant ID: rs1426153

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O63.1 Prolonged second stage (of labour)	0.000	0.961	0.039
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.015	0.985	0.000
O63 Long labour	0.000	0.986	0.014
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.986	0.014
I74 Arterial embolism and thrombosis	0.013	0.987	0.000
I74.5 Embolism and thrombosis of iliac artery	0.013	0.987	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.989	0.011
I74.8 Embolism and thrombosis of other arteries	0.011	0.989	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.011	0.989	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.011	0.989	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.989	0.010
S82.8 Fractures of other parts of lower leg	0.000	0.990	0.010
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.009	0.990	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.009	0.991	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.009	0.991	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.991	0.009
O63.9 Long labour, unspecified	0.000	0.992	0.008
N41.0 Acute prostatitis	0.000	0.992	0.008
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.993	0.007
S82.86 Maisonneuve's fracture	0.000	0.993	0.007
N41 Inflammatory diseases of prostate	0.000	0.993	0.007
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.994	0.006
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.994	0.006
H53.4 Visual field defects	0.000	0.994	0.006
N41.8 Other inflammatory diseases of prostate	0.000	0.995	0.005
N41.3 Prostatocystitis	0.000	0.995	0.005
N41.2 Abscess of prostate	0.000	0.995	0.005
N93.0 Postcoital and contact bleeding	0.000	0.995	0.005
S52.00 Fracture of upper end of ulna (closed)	0.000	0.996	0.004
N41.1 Chronic prostatitis	0.000	0.996	0.004
N93 Other abnormal uterine and vaginal bleeding	0.000	0.996	0.004
M67.8 Other specified disorders of synovium and tendon	0.000	0.996	0.004
S82.50 Fracture of medial malleolus (closed)	0.000	0.996	0.004
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.996	0.004
R09.3 Abnormal sputum	0.004	0.996	0.000
C18.9 Colon, unspecified	0.000	0.997	0.003
D32.9 Meninges, unspecified	0.003	0.997	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
T18.1 Foreign body in oesophagus	0.003	0.997	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
F41.2 Mixed anxiety and depressive disorder	0.003	0.997	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.997	0.003
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.000	0.997	0.003
T18 Foreign body in alimentary tract	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
R45.1 Restlessness and agitation	0.003	0.997	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.003	0.997	0.000
T18.0 Foreign body in mouth	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.997	0.003
H57.0 Anomalies of pupillary function	0.000	0.997	0.003
K29.0 Acute haemorrhagic gastritis	0.000	0.997	0.003
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.997	0.003
M81.98 Osteoporosis, unspecified (Other)	0.002	0.997	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
T18.5 Foreign body in anus and rectum	0.002	0.998	0.000
E06 Thyroiditis	0.002	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
T18.2 Foreign body in stomach	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
K56.1 Intussusception	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.002	0.998	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.002	0.998	0.000
T18.4 Foreign body in colon	0.002	0.998	0.000
T18.3 Foreign body in small intestine	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.998	0.002
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.998	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.002	0.998	0.000
C18.3 Hepatic flexure	0.000	0.998	0.002
L91.0 Keloid scar	0.000	0.998	0.002
S82 Fracture of lower leg, including ankle	0.000	0.998	0.002
F81.9 Developmental disorder of scholastic skills, unspecified	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.000	0.998	0.002
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
K56.0 Paralytic ileus	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
D32 Benign neoplasm of meninges	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
R87.6 Abnormal cytological findings	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
C18.0 Caecum	0.000	0.998	0.002
C91 Lymphoid leukaemia	0.002	0.998	0.000
C91.9 Lymphoid leukaemia, unspecified	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
M24.6 Ankylosis of joint	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
S82.7 Multiple fractures of lower leg	0.000	0.998	0.002
C18.4 Transverse colon	0.000	0.998	0.002
S82.9 Fracture of lower leg, part unspecified	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
Y84.0 Cardiac catheterisation	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
Z42 Follow-up care involving plastic surgery	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.000	0.998	0.002
D32.1 Spinal meninges	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.000	0.998	0.002
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.002	0.998	0.000
B00.3 Herpesviral meningitis	0.002	0.998	0.000
B00.0 Eczema herpeticum	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.002	0.998	0.000
C91.7 Other lymphoid leukaemia	0.002	0.998	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.002	0.998	0.000
C91.5 Adult T-cell leukaemia	0.002	0.998	0.000
C91.3 Prolymphocytic leukaemia	0.002	0.998	0.000
C91.2 Subacute lymphocytic leukaemia	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C91.4 Hairy-cell leukaemia	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
R09.2 Respiratory arrest	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
K56.3 Gallstone ileus	0.000	0.998	0.001
R09.0 Asphyxia	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.998	0.001
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
R45.5 Hostility	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.998	0.001
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
I77.1 Stricture of artery	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.000	0.998	0.001
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.998	0.002
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.001
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.001
W44.0 Home	0.002	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.998	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.001
M79.5 Residual foreign body in soft tissue	0.000	0.998	0.001
N20.0 Calculus of kidney	0.000	0.998	0.002
S82.0 Fracture of patella	0.000	0.998	0.001
M24.29 Disorder of ligament (Site unspecified)	0.001	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.998	0.000
C18.1 Appendix	0.000	0.998	0.001
S82.1 Fracture of upper end of tibia	0.000	0.998	0.001
M24.26 Disorder of ligament (Lower leg)	0.001	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.001
C18.8 Overlapping lesion of colon	0.000	0.998	0.001
C18.5 Splenic flexure	0.000	0.998	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.001
M24.03 Loose body in joint (Forearm)	0.001	0.999	0.000
M24.21 Disorder of ligament (Shoulder region)	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.999	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.999	0.001
H90.3 Sensorineural hearing loss, bilateral	0.001	0.999	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.999	0.001
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.999	0.000
A48.1 Legionnaires' disease	0.000	0.999	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.999	0.001
Z42.9 Follow-up care involving plastic surgery, unspecified	0.001	0.999	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
R45 Symptoms and signs involving emotional state	0.001	0.999	0.000
M24.01 Loose body in joint (Shoulder region)	0.001	0.999	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S82.01 Fracture of patella (open)	0.000	0.999	0.001
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
I05.2 Mitral stenosis with insufficiency	0.001	0.999	0.000
M24.09 Loose body in joint (Site unspecified)	0.001	0.999	0.000
M24.08 Loose body in joint (Other)	0.001	0.999	0.000
M24.06 Loose body in joint-Lower leg	0.001	0.999	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.999	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
F81 Specific developmental disorders of scholastic skills	0.001	0.999	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.999	0.001
B02 Zoster [herpes zoster]	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.001	0.999	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.999	0.001
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.999	0.000
I31.9 Disease of pericardium, unspecified	0.001	0.999	0.000
K56.6 Other and unspecified intestinal obstruction	0.000	0.999	0.001
M84.0 Malunion of fracture	0.001	0.999	0.000
R27.0 Ataxia, unspecified	0.001	0.999	0.000
F20 Schizophrenia	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.001	0.999	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.000	0.999	0.001
M79.58 Residual foreign body in soft tissue (Other)	0.000	0.999	0.001
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.000	0.999	0.001
M79.53 Residual foreign body in soft tissue (Forearm)	0.000	0.999	0.001
M79.52 Residual foreign body in soft tissue (Upper arm)	0.000	0.999	0.001
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.000	0.999	0.001
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.000	0.999	0.001
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
K59.1 Functional diarrhoea	0.000	0.999	0.001
N13.4 Hydroureter	0.000	0.999	0.001
S82.3 Fracture of lower end of tibia	0.000	0.999	0.001
S82.11 Fracture of upper end of tibia (open)	0.000	0.999	0.001
A49.9 Bacterial infection, unspecified	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
H81.1 Benign paroxysmal vertigo	0.001	0.999	0.000
I05.1 Rheumatic mitral insufficiency	0.001	0.999	0.000
I05.0 Mitral stenosis	0.001	0.999	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.999	0.001
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.999	0.000
F20.5 Residual schizophrenia	0.001	0.999	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
K12.1 Other forms of stomatitis	0.001	0.999	0.000
N21.8 Other lower urinary tract calculus	0.001	0.999	0.000
N50.0 Atrophy of testis	0.000	0.999	0.001
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.001	0.999	0.000
Z51.3 Blood transfusion without reported diagnosis	0.001	0.999	0.000
I71 Aortic aneurysm and dissection	0.001	0.999	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.999	0.001
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
K12.0 Recurrent oral aphthae	0.001	0.999	0.000
M84 Disorders of continuity of bone	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
R45.8 Other symptoms and signs involving emotional state	0.001	0.999	0.000
R45.7 State of emotional shock and stress, unspecified	0.001	0.999	0.000
R45.3 Demoralisation and apathy	0.001	0.999	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.999	0.001
N50 Other disorders of male genital organs	0.000	0.999	0.001
M79.56 Residual foreign body in soft tissue (Lower leg)	0.000	0.999	0.001
M84.06 Malunion of fracture (Lower leg)	0.001	0.999	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.999	0.000
M84.03 Malunion of fracture (Forearm)	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
F81.8 Other developmental disorders of scholastic skills	0.001	0.999	0.000
F81.3 Mixed disorder of scholastic skills	0.001	0.999	0.000
F81.2 Specific disorder of arithmetical skills	0.001	0.999	0.000
F81.1 Specific spelling disorder	0.001	0.999	0.000
F81.0 Specific reading disorder	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.999	0.001
J30.1 Allergic rhinitis due to pollen	0.000	0.999	0.001
K14.9 Disease of tongue, unspecified	0.000	0.999	0.001
N75.1 Abscess of Bartholin's gland	0.000	0.999	0.001
H81 Disorders of vestibular function	0.001	0.999	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.001	0.999	0.000
B02.8 Zoster with other complications	0.001	0.999	0.000
B02.7 Disseminated zoster	0.001	0.999	0.000
B02.1 Zoster meningitis	0.001	0.999	0.000
B02.0 Zoster encephalitis	0.001	0.999	0.000
F20.8 Other schizophrenia	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
R45.6 Physical violence	0.001	0.999	0.000
R45.4 Irritability and anger	0.001	0.999	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.001	0.999	0.000
Y83.4 Other reconstructive surgery	0.001	0.999	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
I05 Rheumatic mitral valve diseases	0.001	0.999	0.000
M67 Other disorders of synovium and tendon	0.000	0.999	0.001
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000
M84.09 Malunion of fracture (Site unspecified)	0.001	0.999	0.000
M84.08 Malunion of fracture (Other)	0.001	0.999	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.999	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.001	0.999	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.001	0.999	0.000
K56.2 Volvulus	0.000	0.999	0.001
M84.2 Delayed union of fracture	0.001	0.999	0.000
R45.0 Nervousness	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.999	0.001
K12 Stomatitis and related lesions	0.001	0.999	0.000
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.999	0.001
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
M84.8 Other disorders of continuity of bone	0.001	0.999	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.999	0.001
O23.2 Infections of urethra in pregnancy	0.000	0.999	0.001
O23.1 Infections of bladder in pregnancy	0.000	0.999	0.001
O23.0 Infections of kidney in pregnancy	0.000	0.999	0.001
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
S82.6 Fracture of lateral malleolus	0.000	0.999	0.001
R59 Enlarged lymph nodes	0.000	0.999	0.001
M77.02 Medial epicondylitis (Upper arm)	0.000	0.999	0.001
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.001	0.999	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.999	0.000
C02.1 Border of tongue	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.999	0.000
K12.2 Cellulitis and abscess of mouth	0.001	0.999	0.000
N48.0 Leukoplakia of penis	0.000	0.999	0.001
N85.4 Malposition of uterus	0.000	0.999	0.001
O23.5 Infections of the genital tract in pregnancy	0.000	0.999	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
H81.8 Other disorders of vestibular function	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
H81.3 Other peripheral vertigo	0.001	0.999	0.000
H81.2 Vestibular neuronitis	0.001	0.999	0.000
K10.2 Inflammatory conditions of jaws	0.001	0.999	0.000
K56.7 Ileus, unspecified	0.000	0.999	0.001
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.001	0.999	0.000
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
F21 Schizotypal disorder	0.001	0.999	0.000
O20 Haemorrhage in early pregnancy	0.000	0.999	0.001
I70-I79 Diseases of arteries, arterioles and capillaries	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.999	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.001	0.999	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.999	0.001
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
C90.0 Multiple myeloma	0.001	0.999	0.000
I05.8 Other mitral valve diseases	0.001	0.999	0.000
J18.1 Lobar pneumonia, unspecified	0.001	0.999	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.999	0.001
M67.3 Transient synovitis	0.000	0.999	0.001
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.999	0.001
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.999	0.001
J95.9 Postprocedural respiratory disorder, unspecified	0.001	0.999	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.999	0.001
Z89.5 Acquired absence of leg at or below knee	0.000	0.999	0.001
Z89.4 Acquired absence of foot and ankle	0.000	0.999	0.001
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.999	0.001
G30 Alzheimer's disease	0.000	0.999	0.001
M07.38 Other psoriatic arthropathies (Other)	0.001	0.999	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.001	0.999	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.001	0.999	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations