TreeWAS – Variant ID: rs143384

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.000	1.000
M17.9 Gonarthrosis, unspecified	0.000	0.000	1.000
M20.1 Hallux valgus (acquired)	0.000	0.000	1.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.000	1.000
M23 Internal derangement of knee	0.000	0.000	1.000
M17.1 Other primary gonarthrosis	0.000	0.000	1.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.000	1.000
M20 Acquired deformities of fingers and toes	0.000	0.000	1.000
M20-M25 Other joint disorders	0.000	0.000	1.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.002	0.998
M23.3 Other meniscus derangements	0.000	0.003	0.997
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.011	0.989
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.016	0.984
M20.5 Other deformities of toe(s) (acquired)	0.000	0.017	0.983
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.019	0.981
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.027	0.973
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.036	0.964
M23.8 Other internal derangements of knee	0.000	0.037	0.963
M17.0 Primary gonarthrosis, bilateral	0.000	0.042	0.958
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.052	0.948
M21 Other acquired deformities of limbs	0.000	0.057	0.943
M22 Disorders of patella	0.000	0.065	0.935
M21.1 Varus deformity, not elsewhere classified	0.000	0.074	0.926
M17.3 Other posttraumatic gonarthrosis	0.000	0.076	0.924
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.086	0.914
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.911	0.089	0.000
I80 Phlebitis and thrombophlebitis	0.906	0.094	0.000
M24 Other specific joint derangements	0.000	0.094	0.906
M23.4 Loose body in knee	0.000	0.095	0.905
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.893	0.107	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.107	0.893
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.888	0.112	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.117	0.883
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.118	0.882
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.123	0.877
M24.1 Other articular cartilage disorders	0.000	0.127	0.873
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.138	0.862
M23.49 Loose body in knee-Unspec lig/men	0.000	0.139	0.861
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.158	0.842
M22.2 Patellofemoral disorders	0.000	0.163	0.837
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.169	0.831
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.178	0.822
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.817	0.183	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.184	0.816
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.188	0.812
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.193	0.807
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.203	0.797
M23.46 Loose body in knee-O/unsp lat men	0.000	0.205	0.795
M23.0 Cystic meniscus	0.000	0.205	0.795
M22.3 Other derangements of patella	0.000	0.212	0.788
M22.0 Recurrent dislocation of patella	0.000	0.216	0.784
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.223	0.777
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.228	0.772
M33 Dermatopolymyositis	0.000	0.229	0.770
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.230	0.770
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.243	0.757
M20.0 Deformity of finger(s)	0.000	0.258	0.741
M24.6 Ankylosis of joint	0.000	0.262	0.738
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.266	0.734
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.275	0.725
M21.6 Other acquired deformities of ankle and foot	0.000	0.282	0.718
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.283	0.717
M23.37 Other meniscus derangements-Capsular lig	0.000	0.285	0.715
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.288	0.712
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.289	0.711
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.303	0.697
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.304	0.696
M23.1 Discoid meniscus (congenital)	0.000	0.305	0.695
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.310	0.690
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.310	0.690
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.310	0.690
M22.8 Other disorders of patella	0.000	0.316	0.684
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.317	0.683
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.324	0.676
M22.9 Disorder of patella, unspecified	0.000	0.324	0.676
M21.9 Acquired deformity of limb, unspecified	0.000	0.327	0.673
M22.1 Recurrent subluxation of patella	0.000	0.330	0.670
M32 Systemic lupus erythematosus	0.000	0.335	0.665
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.336	0.664
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.336	0.664
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.336	0.664
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.336	0.664
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.336	0.664
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.336	0.664
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.336	0.664
M24.5 Contracture of joint	0.000	0.339	0.661
M23.9 Internal derangement of knee, unspecified	0.000	0.340	0.660
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.342	0.658
M33.1 Other dermatomyositis	0.000	0.344	0.656
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.344	0.656
M23.47 Loose body in knee-Capsular lig	0.000	0.351	0.649
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.351	0.649
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.351	0.649
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.359	0.641
M21.8 Other specified acquired deformities of limbs	0.000	0.361	0.639
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.367	0.633
M23.40 Loose body in knee-Mult sites	0.000	0.368	0.632
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.374	0.626
M24.18 Other articular cartilage disorders (Other)	0.000	0.374	0.626
M24.14 Other articular cartilage disorders (Hand)	0.000	0.374	0.626
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.374	0.626
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.374	0.626
M17.5 Other secondary gonarthrosis	0.000	0.376	0.624
M30 Polyarteritis nodosa and related conditions	0.000	0.383	0.617
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.386	0.614
M24.9 Joint derangement, unspecified	0.000	0.387	0.613
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.390	0.610
M23.5 Chronic instability of knee	0.000	0.395	0.605
I80.8 Phlebitis and thrombophlebitis of other sites	0.605	0.395	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.396	0.604
M24.66 Ankylosis of joint (Lower leg)	0.000	0.403	0.597
M24.7 Protrusio acetabuli	0.000	0.408	0.591
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.414	0.586
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.415	0.585
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.415	0.585
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.415	0.585
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.415	0.585
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.415	0.585
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.415	0.585
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.415	0.585
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.415	0.585
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.415	0.585
M21.3 Wrist or foot drop (acquired)	0.000	0.415	0.585
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.417	0.583
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.418	0.582
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.420	0.580
M23.43 Loose body in knee-Med lig/oth men	0.000	0.424	0.576
M23.07 Cystic meniscus-Capsular lig	0.000	0.430	0.570
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.430	0.570
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.430	0.570
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.430	0.570
M23.00 Cystic meniscus (Multiple sites)	0.000	0.430	0.570
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.443	0.557
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.443	0.557
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.443	0.557
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.443	0.557
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.443	0.557
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.443	0.557
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.443	0.557
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.443	0.557
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.443	0.557
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.444	0.556
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.446	0.553
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.446	0.553
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.446	0.553
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.446	0.553
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.446	0.553
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.446	0.553
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.446	0.553
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.446	0.553
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.446	0.553
M33.9 Dermatopolymyositis, unspecified	0.000	0.447	0.552
M33.0 Juvenile dermatomyositis	0.000	0.447	0.552
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.449	0.551
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.457	0.543
M36.3 Arthropathy in other blood disorders	0.000	0.457	0.543
M36.2 Haemophilic arthropathy	0.000	0.457	0.543
M36.1 Arthropathy in neoplastic disease	0.000	0.457	0.543
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.457	0.543
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.458	0.542
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.461	0.538
M21.0 Valgus deformity, not elsewhere classified	0.000	0.469	0.531
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.471	0.529
M24.68 Ankylosis of joint (Other)	0.000	0.471	0.529
M24.63 Ankylosis of joint (Forearm)	0.000	0.471	0.529
M24.62 Ankylosis of joint (Upper arm)	0.000	0.471	0.529
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.471	0.529
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.471	0.529
M24.56 Contracture of joint (Lower leg)	0.000	0.474	0.525
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.477	0.523
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.481	0.519
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.484	0.515
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.485	0.515
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.485	0.515
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.485	0.515
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.485	0.515
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.485	0.515
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.485	0.515
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.485	0.515
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.485	0.515
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.485	0.515
M22.4 Chondromalacia patellae	0.000	0.488	0.512
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.491	0.508
M20.3 Other deformity of hallux (acquired)	0.000	0.492	0.508
M32.8 Other forms of systemic lupus erythematosus	0.000	0.498	0.502
M24.2 Disorder of ligament	0.000	0.501	0.499
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.501	0.498
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.501	0.498
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.501	0.498
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.501	0.498
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.501	0.498
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.501	0.498
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.501	0.498
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.501	0.498
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.504	0.496
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.504	0.496
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.510	0.490
M24.57 Contracture of joint (Ankle and foot)	0.000	0.510	0.490
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.512	0.488
M24.64 Ankylosis of joint (Hand)	0.000	0.513	0.487
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.517	0.483
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.517	0.483
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.517	0.483
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.517	0.483
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.517	0.483
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.517	0.483
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.517	0.483
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.517	0.483
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.517	0.483
M24.52 Contracture of joint (Upper arm)	0.000	0.519	0.481
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.519	0.481
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.519	0.481
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.523	0.477
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.523	0.477
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.523	0.477
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.526	0.474
M24.59 Contracture of joint (Site unspecified)	0.000	0.526	0.474
M24.58 Contracture of joint (Other)	0.000	0.526	0.474
M24.53 Contracture of joint (Forearm)	0.000	0.526	0.474
M24.50 Contracture of joint (Multiple sites)	0.000	0.526	0.474
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.526	0.473
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.526	0.473
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.526	0.473
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.526	0.473
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.526	0.473
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.526	0.473
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.526	0.473
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.529	0.471
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.529	0.471
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.530	0.470
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.530	0.470
M24.51 Contracture of joint (Shoulder region)	0.000	0.531	0.469
M20.4 Other hammer toe(s) (acquired)	0.000	0.533	0.467
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.538	0.462
R59.1 Generalised enlarged lymph nodes	0.461	0.539	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.541	0.459
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.542	0.458
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.542	0.458
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.542	0.458
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.542	0.458
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.542	0.458
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.542	0.458
M33.2 Polymyositis	0.000	0.543	0.457
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.544	0.456
M21.7 Unequal limb length (acquired)	0.001	0.548	0.452
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.548	0.452
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.555	0.445
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.557	0.443
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.558	0.442
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.558	0.442
M30.2 Juvenile polyarteritis	0.000	0.558	0.442
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.558	0.442
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.560	0.440
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.560	0.440
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.560	0.440
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.560	0.440
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.560	0.440
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.560	0.440
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.560	0.440
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.560	0.440
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.560	0.439
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.560	0.439
M24.98 Joint derangement, unspecified (Other)	0.000	0.560	0.439
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.560	0.439
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.560	0.439
M24.94 Joint derangement, unspecified (Hand)	0.000	0.560	0.439
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.560	0.439
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.560	0.439
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.560	0.439
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.560	0.439
R59.0 Localised enlarged lymph nodes	0.439	0.561	0.000
R59 Enlarged lymph nodes	0.438	0.562	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.566	0.434
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.566	0.434
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.566	0.434
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.566	0.434
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.566	0.434
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.566	0.434
M24.24 Disorder of ligament (Hand)	0.000	0.568	0.432
M23.41 Loose body in knee-Ant lig/hrn men	0.001	0.571	0.428
M24.79 Protrusio acetabuli-Site unspec	0.000	0.576	0.424
M24.78 Protrusio acetabuli-Other	0.000	0.576	0.424
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.576	0.424
M24.76 Protrusio acetabuli-Lower leg	0.000	0.576	0.424
M24.74 Protrusio acetabuli-Hand	0.000	0.576	0.424
M24.73 Protrusio acetabuli-Forearm	0.000	0.576	0.424
M24.72 Protrusio acetabuli-Upper arm	0.000	0.576	0.424
M24.71 Protrusio acetabuli-Shldr region	0.000	0.576	0.424
M24.70 Protrusio acetabuli-Mult sites	0.000	0.576	0.424
M24.23 Disorder of ligament (Forearm)	0.000	0.578	0.422
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.580	0.419
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.580	0.419
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.580	0.419
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.580	0.419
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.580	0.419
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.580	0.419
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.580	0.419
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.580	0.419
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.583	0.417
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.583	0.417
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.583	0.417
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.583	0.417
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.583	0.417
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.583	0.417
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.584	0.416
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.586	0.413
M34 Systemic sclerosis	0.000	0.587	0.413
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.596	0.404
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.597	0.403
M30.0 Polyarteritis nodosa	0.000	0.609	0.391
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.613	0.387
M21.2 Flexion deformity	0.001	0.618	0.381
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.619	0.381
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.619	0.381
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.619	0.381
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.619	0.381
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.619	0.381
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.619	0.381
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.619	0.381
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.619	0.381
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.626	0.374
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.634	0.366
M24.29 Disorder of ligament (Site unspecified)	0.000	0.642	0.358
M24.22 Disorder of ligament (Upper arm)	0.000	0.642	0.358
M24.20 Disorder of ligament (Multiple sites)	0.000	0.642	0.358
M24.54 Contracture of joint (Hand)	0.000	0.644	0.356
M24.26 Disorder of ligament (Lower leg)	0.000	0.656	0.344
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.658	0.342
K44 Diaphragmatic hernia	0.000	0.660	0.340
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.663	0.337
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.663	0.337
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.666	0.334
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.667	0.332
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.674	0.326
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.674	0.325
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.675	0.324
M21.78 Unequal limb length (acquired)-Other	0.001	0.675	0.324
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.675	0.324
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.675	0.324
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.675	0.324
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.675	0.324
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.675	0.324
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.676	0.324
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.679	0.320
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.683	0.317
M21.27 Flexion deformity (Ankle and foot)	0.000	0.683	0.316
M24.0 Loose body in joint	0.000	0.689	0.310
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.704	0.296
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.705	0.294
M24.28 Disorder of ligament (Other)	0.000	0.710	0.289
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.711	0.289
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.712	0.287
M34.1 CR(E)ST syndrome	0.000	0.713	0.287
M21.29 Flexion deformity (Site unspecified)	0.001	0.726	0.273
M21.28 Flexion deformity (Other)	0.001	0.726	0.273
M21.23 Flexion deformity (Forearm)	0.001	0.726	0.273
M21.21 Flexion deformity (Shoulder region)	0.001	0.726	0.273
M21.20 Flexion deformity (Multiple sites)	0.001	0.726	0.273
M35 Other systemic involvement of connective tissue	0.000	0.727	0.273
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.729	0.271
M34.0 Progressive systemic sclerosis	0.000	0.732	0.268
M21.22 Flexion deformity (Upper arm)	0.001	0.736	0.264
R59.9 Enlarged lymph nodes, unspecified	0.259	0.741	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.745	0.255
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.749	0.250
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.749	0.251
M34.8 Other forms of systemic sclerosis	0.000	0.759	0.241
M24.06 Loose body in joint-Lower leg	0.000	0.763	0.237
M24.21 Disorder of ligament (Shoulder region)	0.001	0.764	0.235
M24.04 Loose body in joint (Hand)	0.000	0.769	0.231
M35.1 Other overlap syndromes	0.000	0.772	0.228
M24.09 Loose body in joint (Site unspecified)	0.000	0.777	0.223
M24.08 Loose body in joint (Other)	0.000	0.777	0.223
M24.00 Loose body in joint (Multiple sites)	0.000	0.777	0.223
M35.7 Hypermobility syndrome	0.000	0.781	0.219
M25 Other joint disorders, not elsewhere classified	0.000	0.787	0.213
M21.24 Flexion deformity (Hand)	0.001	0.789	0.210
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.209	0.791	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.792	0.208
M31 Other necrotising vasculopathies	0.000	0.797	0.202
M34.9 Systemic sclerosis, unspecified	0.000	0.801	0.199
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.804	0.196
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.804	0.196
M35.5 Multifocal fibrosclerosis	0.000	0.804	0.196
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.806	0.194
M24.03 Loose body in joint (Forearm)	0.000	0.814	0.186
M25.3 Other instability of joint	0.000	0.817	0.183
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.182	0.818	0.001
K44.1 Diaphragmatic hernia with gangrene	0.000	0.822	0.177
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.823	0.176
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.824	0.176
M21.26 Flexion deformity (Lower leg)	0.001	0.824	0.175
M25.8 Other specified joint disorders	0.000	0.825	0.175
M25.34 Other instability of joint (Hand)	0.000	0.825	0.175
M24.01 Loose body in joint (Shoulder region)	0.000	0.826	0.174
M35.2 Behcet's disease	0.000	0.829	0.171
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.833	0.167
M35.8 Other specified systemic involvement of connective tissue	0.000	0.843	0.157
M25.2 Flail joint	0.000	0.847	0.153
M25.1 Fistula of joint	0.000	0.847	0.153
M31.1 Thrombotic microangiopathy	0.000	0.847	0.152
M25.4 Effusion of joint	0.000	0.850	0.150
M31.7 Microscopic polyangiitis	0.000	0.851	0.148
M24.02 Loose body in joint (Upper arm)	0.000	0.853	0.147
M25.7 Osteophyte	0.000	0.854	0.146
M31.2 Lethal midline granuloma	0.000	0.854	0.145
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.855	0.145
M31.9 Necrotising vasculopathy, unspecified	0.000	0.856	0.143
M31.3 Wegener's granulomatosis	0.000	0.858	0.142
M25.83 Other specified joint disorders (Forearm)	0.000	0.858	0.142
M25.33 Other instability of joint (Forearm)	0.000	0.859	0.141
M25.76 Osteophyte (Lower leg)	0.000	0.859	0.141
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.859	0.140
I26 Pulmonary embolism	0.138	0.862	0.000
M25.0 Haemarthrosis	0.000	0.866	0.133
M25.43 Effusion of joint (Forearm)	0.000	0.867	0.133
M25.36 Other instability of joint (Lower leg)	0.000	0.868	0.132
M25.39 Other instability of joint (Site unspecified)	0.000	0.868	0.132
M25.38 Other instability of joint (Other)	0.000	0.868	0.132
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.868	0.132
M25.32 Other instability of joint (Upper arm)	0.000	0.868	0.132
M25.30 Other instability of joint (Multiple sites)	0.000	0.868	0.132
M31.8 Other specified necrotising vasculopathies	0.000	0.870	0.130
M31.0 Hypersensitivity angiitis	0.000	0.872	0.127
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.874	0.126
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.874	0.126
M25.71 Osteophyte (Shoulder region)	0.000	0.876	0.124
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.879	0.120
M15-M19 Arthrosis	0.000	0.881	0.119
M25.86 Other specified joint disorders (Lower leg)	0.000	0.881	0.119
M25.40 Effusion of joint (Multiple sites)	0.000	0.884	0.116
M25.44 Effusion of joint (Hand)	0.000	0.887	0.113
M25.74 Osteophyte (Hand)	0.000	0.887	0.113
M25.72 Osteophyte (Upper arm)	0.000	0.888	0.112
M25.37 Other instability of joint (Ankle and foot)	0.000	0.890	0.110
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.110	0.890	0.000
M25.19 Fistula of joint (Site unspecified)	0.000	0.890	0.110
M25.18 Fistula of joint (Other)	0.000	0.890	0.110
M25.17 Fistula of joint (Ankle and foot)	0.000	0.890	0.110
M25.16 Fistula of joint (Lower leg)	0.000	0.890	0.110
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.890	0.110
M25.14 Fistula of joint (Hand)	0.000	0.890	0.110
M25.13 Fistula of joint (Forearm)	0.000	0.890	0.110
M25.12 Fistula of joint (Upper arm)	0.000	0.890	0.110
M25.11 Fistula of joint (Shoulder region)	0.000	0.890	0.110
M25.10 Fistula of joint (Multiple sites)	0.000	0.890	0.110
M25.29 Flail joint (Site unspecified)	0.000	0.890	0.110
M25.28 Flail joint (Other)	0.000	0.890	0.110
M25.27 Flail joint (Ankle and foot)	0.000	0.890	0.110
M25.26 Flail joint (Lower leg)	0.000	0.890	0.110
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.890	0.110
M25.24 Flail joint (Hand)	0.000	0.890	0.110
M25.23 Flail joint (Forearm)	0.000	0.890	0.110
M25.22 Flail joint (Upper arm)	0.000	0.890	0.110
M25.21 Flail joint (Shoulder region)	0.000	0.890	0.110
M25.20 Flail joint (Multiple sites)	0.000	0.890	0.110
M25.73 Osteophyte (Forearm)	0.000	0.891	0.109
M25.82 Other specified joint disorders (Upper arm)	0.000	0.892	0.108
M25.49 Effusion of joint (Site unspecified)	0.000	0.892	0.108
M25.48 Effusion of joint (Other)	0.000	0.892	0.108
M25.70 Osteophyte (Multiple sites)	0.000	0.895	0.105
M25.46 Effusion of joint (Lower leg)	0.000	0.900	0.100
M25.88 Other specified joint disorders (Other)	0.000	0.900	0.100
M25.47 Effusion of joint (Ankle and foot)	0.000	0.900	0.100
M25.42 Effusion of joint (Upper arm)	0.000	0.900	0.100
M25.79 Osteophyte (Site unspecified)	0.000	0.904	0.096
M25.09 Haemarthrosis (Site unspecified)	0.000	0.904	0.096
M25.08 Haemarthrosis (Other)	0.000	0.904	0.096
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.904	0.096
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.904	0.096
M25.04 Haemarthrosis (Hand)	0.000	0.904	0.096
M25.03 Haemarthrosis (Forearm)	0.000	0.904	0.096
M25.02 Haemarthrosis (Upper arm)	0.000	0.904	0.096
M25.01 Haemarthrosis (Shoulder region)	0.000	0.904	0.096
M25.00 Haemarthrosis (Multiple sites)	0.000	0.904	0.096
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.905	0.095
M15 Polyarthrosis	0.000	0.907	0.093
M65.34 Trigger finger-Hand	0.000	0.908	0.092
M25.41 Effusion of joint (Shoulder region)	0.000	0.910	0.090
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.912	0.088
M25.56 Pain in joint (Lower leg)	0.000	0.916	0.084
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.916	0.083
M35.3 Polymyalgia rheumatica	0.000	0.918	0.082
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.919	0.081
M65.3 Trigger finger	0.000	0.919	0.081
M25.84 Other specified joint disorders (Hand)	0.000	0.920	0.080
M25.5 Pain in joint	0.000	0.920	0.080
M65-M68 Disorders of synovium and tendon	0.000	0.922	0.078
M25.06 Haemarthrosis (Lower leg)	0.000	0.924	0.076
M25.31 Other instability of joint (Shoulder region)	0.000	0.926	0.074
M65 Synovitis and tenosynovitis	0.000	0.927	0.073
M15.3 Secondary multiple arthrosis	0.000	0.927	0.073
M15.8 Other polyarthrosis	0.000	0.928	0.072
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.928	0.071
M15.1 Heberden's nodes (with arthropathy)	0.000	0.928	0.071
M31.6 Other giant cell arteritis	0.000	0.930	0.070
M15.0 Primary generalised (osteo)arthrosis	0.000	0.933	0.067
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.066	0.934	0.000
M15.9 Polyarthrosis, unspecified	0.000	0.936	0.064
M66 Spontaneous rupture of synovium and tendon	0.000	0.937	0.063

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations