TreeWAS – Variant ID: rs1443438

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E04.2 Non-toxic multinodular goitre	1.000	0.000	0.000
E04 Other non-toxic goitre	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E04.9 Non-toxic goitre, unspecified	1.000	0.000	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.003	0.997
E07 Other disorders of thyroid	0.951	0.049	0.000
E07.9 Disorder of thyroid, unspecified	0.915	0.085	0.000
E04.0 Non-toxic diffuse goitre	0.877	0.123	0.000
E03.1 Congenital hypothyroidism without goitre	0.844	0.156	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.838	0.162	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.830	0.170	0.000
E03.8 Other specified hypothyroidism	0.825	0.175	0.000
E06 Thyroiditis	0.819	0.181	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.771	0.229	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.768	0.232	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.750	0.250	0.000
E04.8 Other specified non-toxic goitre	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E07.8 Other specified disorders of thyroid	0.690	0.310	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.685	0.315	0.000
E07.1 Dyshormogenetic goitre	0.682	0.318	0.000
E07.0 Hypersecretion of calcitonin	0.682	0.318	0.000
E06.3 Autoimmune thyroiditis	0.648	0.352	0.000
E06.5 Other chronic thyroiditis	0.643	0.357	0.000
E05.8 Other thyrotoxicosis	0.628	0.372	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.601	0.399	0.000
E06.9 Thyroiditis, unspecified	0.601	0.399	0.000
E05.5 Thyroid crisis or storm	0.601	0.399	0.000
E05.4 Thyrotoxicosis factitia	0.601	0.399	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.601	0.399	0.000
E06.4 Drug-induced thyroiditis	0.587	0.413	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.587	0.413	0.000
E06.0 Acute thyroiditis	0.587	0.413	0.000
E06.1 Subacute thyroiditis	0.570	0.429	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.712	0.288
E23 Hypofunction and other disorders of pituitary gland	0.248	0.752	0.000
E20-E35 Disorders of other endocrine glands	0.243	0.757	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.241	0.759	0.000
E23.0 Hypopituitarism	0.241	0.759	0.000
E23.2 Diabetes insipidus	0.229	0.771	0.000
E04.1 Non-toxic single thyroid nodule	0.223	0.776	0.000
E23.7 Disorder of pituitary gland, unspecified	0.217	0.783	0.000
E29 Testicular dysfunction	0.213	0.787	0.000
E34 Other endocrine disorders	0.209	0.791	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.197	0.803	0.000
E29.1 Testicular hypofunction	0.191	0.809	0.000
E28 Ovarian dysfunction	0.191	0.809	0.000
E34.9 Endocrine disorder, unspecified	0.191	0.809	0.000
E31 Polyglandular dysfunction	0.186	0.814	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.819	0.181
E23.1 Drug-induced hypopituitarism	0.178	0.822	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.822	0.178
E25 Adrenogenital disorders	0.177	0.823	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.175	0.825	0.000
E30 Disorders of puberty, not elsewhere classified	0.175	0.825	0.000
E32 Diseases of thymus	0.173	0.826	0.000
E20 Hypoparathyroidism	0.169	0.831	0.000
E26 Hyperaldosteronism	0.166	0.834	0.000
E27 Other disorders of adrenal gland	0.161	0.839	0.000
E24 Cushing's syndrome	0.160	0.840	0.000
E28.3 Primary ovarian failure	0.159	0.841	0.000
E89.0 Postprocedural hypothyroidism	0.158	0.842	0.000
E29.8 Other testicular dysfunction	0.153	0.847	0.000
E29.0 Testicular hyperfunction	0.153	0.847	0.000
E29.9 Testicular dysfunction, unspecified	0.153	0.847	0.000
E34.8 Other specified endocrine disorders	0.152	0.848	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.152	0.848	0.000
E34.5 Androgen resistance syndrome	0.150	0.850	0.000
E34.4 Constitutional tall stature	0.150	0.850	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.150	0.850	0.000
E34.1 Other hypersecretion of intestinal hormones	0.150	0.850	0.000
E05.9 Thyrotoxicosis, unspecified	0.148	0.852	0.000
E70-E90 Metabolic disorders	0.147	0.853	0.000
E34.0 Carcinoid syndrome	0.146	0.854	0.000
E31.0 Autoimmune polyglandular failure	0.146	0.854	0.000
E22 Hyperfunction of pituitary gland	0.138	0.862	0.000
E40-E46 Malnutrition	0.138	0.862	0.000
E28.9 Ovarian dysfunction, unspecified	0.137	0.863	0.000
E28.8 Other ovarian dysfunction	0.137	0.863	0.000
E28.1 Androgen excess	0.137	0.863	0.000
E28.0 Oestrogen excess	0.137	0.863	0.000
C75.0 Parathyroid gland	0.000	0.865	0.135
E23.6 Other disorders of pituitary gland	0.134	0.866	0.000
E31.9 Polyglandular dysfunction, unspecified	0.134	0.866	0.000
E31.8 Other polyglandular dysfunction	0.134	0.866	0.000
E31.1 Polyglandular hyperfunction	0.134	0.866	0.000
C75.8 Pluriglandular involvement, unspecified	0.000	0.870	0.130
C75.5 Aortic body and other paraganglia	0.000	0.870	0.130
C75.4 Carotid body	0.000	0.870	0.130
C75.3 Pineal gland	0.000	0.870	0.130
C75.2 Craniopharyngeal duct	0.000	0.870	0.130
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.130	0.870	0.000
E20.8 Other hypoparathyroidism	0.130	0.870	0.000
C74.1 Medulla of adrenal gland	0.000	0.871	0.129
E28.2 Polycystic ovarian syndrome	0.129	0.871	0.000
E34.3 Short stature, not elsewhere classified	0.129	0.871	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.129	0.871	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.129	0.871	0.000
E25.9 Adrenogenital disorder, unspecified	0.127	0.873	0.000
E25.8 Other adrenogenital disorders	0.127	0.873	0.000
E30.9 Disorder of puberty, unspecified	0.125	0.874	0.000
E30.8 Other disorders of puberty	0.125	0.874	0.000
E30.1 Precocious puberty	0.125	0.874	0.000
E30.0 Delayed puberty	0.125	0.874	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.125	0.874	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.125	0.874	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.125	0.874	0.000
C74.9 Adrenal gland, unspecified	0.000	0.875	0.125
E85 Amyloidosis	0.125	0.875	0.000
E32.8 Other diseases of thymus	0.124	0.875	0.000
E32.1 Abscess of thymus	0.124	0.875	0.000
E32.0 Persistent hyperplasia of thymus	0.124	0.875	0.000
E32.9 Disease of thymus, unspecified	0.123	0.876	0.000
E89.4 Postprocedural ovarian failure	0.123	0.877	0.000
E24.8 Other Cushing's syndrome	0.122	0.878	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.122	0.878	0.000
E20.0 Idiopathic hypoparathyroidism	0.121	0.878	0.000
E79 Disorders of purine and pyrimidine metabolism	0.121	0.879	0.000
E20.1 Pseudohypoparathyroidism	0.120	0.879	0.000
E27.9 Disorder of adrenal gland, unspecified	0.120	0.880	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.120	0.880	0.000
E26.8 Other hyperaldosteronism	0.119	0.881	0.000
E26.1 Secondary hyperaldosteronism	0.119	0.881	0.000
E84 Cystic fibrosis	0.119	0.881	0.000
E88 Other metabolic disorders	0.118	0.882	0.000
E27.1 Primary adrenocortical insufficiency	0.117	0.883	0.000
E26.9 Hyperaldosteronism, unspecified	0.117	0.883	0.000
C75.9 Endocrine gland, unspecified	0.000	0.884	0.116
E27.5 Adrenomedullary hyperfunction	0.116	0.884	0.000
E27.0 Other adrenocortical overactivity	0.116	0.884	0.000
C75.1 Pituitary gland	0.000	0.884	0.115
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.115	0.885	0.000
E24.3 Ectopic ACTH syndrome	0.115	0.885	0.000
E24.1 Nelson's syndrome	0.115	0.885	0.000
E26.0 Primary hyperaldosteronism	0.113	0.887	0.000
E24.2 Drug-induced Cushing's syndrome	0.112	0.887	0.000
E72 Other disorders of amino-acid metabolism	0.112	0.888	0.000
E24.9 Cushing's syndrome, unspecified	0.111	0.889	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.111	0.889	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.109	0.891	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.108	0.891	0.000
E74 Other disorders of carbohydrate metabolism	0.107	0.893	0.000
E89.5 Postprocedural testicular hypofunction	0.106	0.893	0.000
E89.3 Postprocedural hypopituitarism	0.106	0.894	0.000
E20.9 Hypoparathyroidism, unspecified	0.106	0.894	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.106	0.894	0.000
E77 Disorders of glycoprotein metabolism	0.106	0.894	0.000
E76 Disorders of glycosaminoglycan metabolism	0.106	0.894	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.106	0.894	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.106	0.894	0.000
E70 Disorders of aromatic amino-acid metabolism	0.102	0.897	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.102	0.898	0.000
E89.1 Postprocedural hypoinsulinaemia	0.101	0.898	0.000
C74.0 Cortex of adrenal gland	0.001	0.900	0.100
F60.9 Personality disorder, unspecified	0.000	0.900	0.100
E22.8 Other hyperfunction of pituitary gland	0.099	0.900	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.099	0.901	0.000
E45 Retarded development following protein-energy malnutrition	0.099	0.901	0.000
E43 Unspecified severe protein-energy malnutrition	0.099	0.901	0.000
E42 Marasmic kwashiorkor	0.099	0.901	0.000
E41 Nutritional marasmus	0.099	0.901	0.000
E40 Kwashiorkor	0.099	0.901	0.000
E89.2 Postprocedural hypoparathyroidism	0.099	0.901	0.000
E85.3 Secondary systemic amyloidosis	0.098	0.902	0.000
E85.8 Other amyloidosis	0.098	0.902	0.000
E88.9 Metabolic disorder, unspecified	0.096	0.903	0.000
E24.0 Pituitary-dependent Cushing's disease	0.096	0.904	0.000
E84.9 Cystic fibrosis, unspecified	0.095	0.904	0.000
E85.9 Amyloidosis, unspecified	0.095	0.905	0.000
E88.2 Lipomatosis, not elsewhere classified	0.094	0.906	0.000
E85.4 Organ-limited amyloidosis	0.094	0.906	0.000
E27.2 Addisonian crisis	0.094	0.906	0.000
E27.8 Other specified disorders of adrenal gland	0.094	0.906	0.000
E15 Nondiabetic hypoglycaemic coma	0.093	0.906	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.093	0.907	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.090	0.910	0.000
F60 Specific personality disorders	0.000	0.910	0.090
E85.2 Heredofamilial amyloidosis, unspecified	0.090	0.910	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.090	0.910	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.090	0.910	0.000
Z51.0 Radiotherapy session	0.000	0.910	0.090
F60.3 Emotionally unstable personality disorder	0.000	0.913	0.087
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.087	0.913	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.087	0.913	0.000
E79.1 Lesch-Nyhan syndrome	0.087	0.913	0.000
E84.8 Cystic fibrosis with other manifestations	0.085	0.914	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.085	0.914	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.085	0.915	0.000
E88.8 Other specified metabolic disorders	0.085	0.915	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.084	0.915	0.000
E88.3 Tumour lysis syndrome	0.084	0.916	0.000
E73 Lactose intolerance	0.084	0.916	0.000
E72.0 Disorders of amino-acid transport	0.082	0.918	0.000
E74.0 Glycogen storage disease	0.082	0.918	0.000
E22.0 Acromegaly and pituitary gigantism	0.080	0.920	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.080	0.920	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.080	0.920	0.000
E72.5 Disorders of glycine metabolism	0.080	0.920	0.000
E72.4 Disorders of ornithine metabolism	0.080	0.920	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.080	0.920	0.000
E72.2 Disorders of urea cycle metabolism	0.080	0.920	0.000
F60.7 Dependent personality disorder	0.000	0.921	0.079
E22.1 Hyperprolactinaemia	0.078	0.922	0.000
E75.5 Other lipid storage disorders	0.077	0.923	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.077	0.923	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.077	0.923	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.077	0.923	0.000
E74.2 Disorders of galactose metabolism	0.077	0.923	0.000
E74.1 Disorders of fructose metabolism	0.077	0.923	0.000
E65-E68 Obesity and other hyperalimentation	0.077	0.923	0.000
E75.6 Lipid storage disorder, unspecified	0.076	0.924	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.076	0.924	0.000
E75.3 Sphingolipidosis, unspecified	0.076	0.924	0.000
E75.1 Other gangliosidosis	0.076	0.924	0.000
E75.0 GM2 gangliosidosis	0.076	0.924	0.000
E71.3 Disorders of fatty-acid metabolism	0.076	0.924	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.076	0.924	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.076	0.924	0.000
E71.0 Maple-syrup-urine disease	0.076	0.924	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.076	0.924	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.076	0.924	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.076	0.924	0.000
E76.2 Other mucopolysaccharidoses	0.076	0.924	0.000
E76.1 Mucopolysaccharidosis, type II	0.076	0.924	0.000
E76.0 Mucopolysaccharidosis, type I	0.076	0.924	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.076	0.924	0.000
E77.8 Other disorders of glycoprotein metabolism	0.076	0.924	0.000
E77.1 Defects in glycoprotein degradation	0.076	0.924	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.076	0.924	0.000
E75.2 Other sphingolipidosis	0.075	0.925	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.074	0.926	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.074	0.926	0.000
E70.2 Disorders of tyrosine metabolism	0.074	0.926	0.000
E70.1 Other hyperphenylalaninaemias	0.074	0.926	0.000
E70.0 Classical phenylketonuria	0.074	0.926	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.072	0.928	0.000
E44.1 Mild protein-energy malnutrition	0.071	0.928	0.000
E44.0 Moderate protein-energy malnutrition	0.071	0.928	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.071	0.928	0.000
E50-E64 Other nutritional deficiencies	0.071	0.929	0.000
E70.3 Albinism	0.071	0.929	0.000
F60.2 Dissocial personality disorder	0.000	0.934	0.066
F60.1 Schizoid personality disorder	0.000	0.935	0.065
F60.4 Histrionic personality disorder	0.000	0.935	0.064
E46 Unspecified protein-energy malnutrition	0.064	0.936	0.000
F60.0 Paranoid personality disorder	0.000	0.937	0.063
F60.8 Other specific personality disorders	0.000	0.937	0.062
E80 Disorders of porphyrin and bilirubin metabolism	0.062	0.938	0.000
E73.8 Other lactose intolerance	0.060	0.940	0.000
E73.1 Secondary lactase deficiency	0.060	0.940	0.000
E73.0 Congenital lactase deficiency	0.060	0.940	0.000
X62.9 Unspecified place	0.000	0.940	0.060
F60.5 Anankastic personality disorder	0.000	0.941	0.058
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.057	0.943	0.000
E67 Other hyperalimentation	0.055	0.945	0.000
E68 Sequelae of hyperalimentation	0.055	0.945	0.000
E63 Other nutritional deficiencies	0.052	0.948	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.051	0.949	0.000
E50 Vitamin A deficiency	0.051	0.949	0.000
E60 Dietary zinc deficiency	0.051	0.949	0.000
E59 Dietary selenium deficiency	0.051	0.949	0.000
E54 Ascorbic acid deficiency	0.051	0.949	0.000
E52 Niacin deficiency [pellagra]	0.051	0.949	0.000
E16 Other disorders of pancreatic internal secretion	0.050	0.950	0.000
E51 Thiamine deficiency	0.050	0.950	0.000
E61 Deficiency of other nutrient elements	0.049	0.951	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.954	0.046
E80.7 Disorder of bilirubin metabolism, unspecified	0.044	0.956	0.000
E80.5 Crigler-Najjar syndrome	0.044	0.956	0.000
E80.3 Defects of catalase and peroxydase	0.044	0.956	0.000
E80.0 Hereditary erythropoietic porphyria	0.044	0.956	0.000
E58 Dietary calcium deficiency	0.044	0.956	0.000
E56 Other vitamin deficiencies	0.043	0.956	0.000
F60-F69 Disorders of adult personality and behaviour	0.000	0.956	0.044
E21.4 Other specified disorders of parathyroid gland	0.043	0.957	0.000
E80.1 Porphyria cutanea tarda	0.042	0.958	0.000
E80.6 Other disorders of bilirubin metabolism	0.042	0.958	0.000
Z48.8 Other specified surgical follow-up care	0.042	0.958	0.000
E53 Deficiency of other B group vitamins	0.041	0.958	0.000
E80.2 Other porphyria	0.041	0.959	0.000
E21.2 Other hyperparathyroidism	0.041	0.959	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.040	0.960	0.000
E67.8 Other specified hyperalimentation	0.040	0.960	0.000
E67.3 Hypervitaminosis D	0.040	0.960	0.000
E67.2 Megavitamin-B6 syndrome	0.040	0.960	0.000
E67.1 Hypercarotenaemia	0.040	0.960	0.000
E67.0 Hypervitaminosis A	0.040	0.960	0.000
E73.9 Lactose intolerance, unspecified	0.038	0.961	0.000
E63.9 Nutritional deficiency, unspecified	0.038	0.962	0.000
E63.8 Other specified nutritional deficiencies	0.037	0.962	0.000
E63.1 Imbalance of constituents of food intake	0.037	0.962	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.037	0.962	0.000
E50.9 Vitamin A deficiency, unspecified	0.037	0.963	0.000
E50.8 Other manifestations of vitamin A deficiency	0.037	0.963	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.037	0.963	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.037	0.963	0.000
E50.5 Vitamin A deficiency with night blindness	0.037	0.963	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.037	0.963	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.037	0.963	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.037	0.963	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.037	0.963	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.037	0.963	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.037	0.963	0.000
E64.8 Sequelae of other nutritional deficiencies	0.037	0.963	0.000
E64.3 Sequelae of rickets	0.037	0.963	0.000
E64.2 Sequelae of vitamin C deficiency	0.037	0.963	0.000
E64.1 Sequelae of vitamin A deficiency	0.037	0.963	0.000
E64.0 Sequelae of protein-energy malnutrition	0.037	0.963	0.000
E61.1 Iron deficiency	0.037	0.963	0.000
E65 Localised adiposity	0.036	0.964	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.036	0.964	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.036	0.964	0.000
E16.4 Abnormal secretion of gastrin	0.036	0.964	0.000
E16.3 Increased secretion of glucagon	0.036	0.964	0.000
E51.9 Thiamine deficiency, unspecified	0.036	0.964	0.000
E51.8 Other manifestations of thiamine deficiency	0.036	0.964	0.000
E51.1 Beriberi	0.036	0.964	0.000
E61.9 Deficiency of nutrient element, unspecified	0.035	0.964	0.000
E61.8 Deficiency of other specified nutrient elements	0.035	0.964	0.000
E61.7 Deficiency of multiple nutrient elements	0.035	0.964	0.000
E61.6 Vanadium deficiency	0.035	0.964	0.000
E61.5 Molybdenum deficiency	0.035	0.964	0.000
E61.4 Chromium deficiency	0.035	0.964	0.000
E61.3 Manganese deficiency	0.035	0.964	0.000
E61.0 Copper deficiency	0.035	0.964	0.000
E16.1 Other hypoglycaemia	0.035	0.965	0.000
F64 Gender identity disorders	0.000	0.965	0.035
E51.2 Wernicke's encephalopathy	0.035	0.965	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.967	0.033
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.967	0.033
E55 Vitamin D deficiency	0.033	0.967	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.032	0.968	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.032	0.968	0.000
E61.2 Magnesium deficiency	0.032	0.968	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.968	0.032
F61 Mixed and other personality disorders	0.000	0.968	0.032
E56.9 Vitamin deficiency, unspecified	0.031	0.968	0.000
E56.8 Deficiency of other vitamins	0.031	0.968	0.000
E56.0 Deficiency of vitamin E	0.031	0.968	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.968	0.032
F65 Disorders of sexual preference	0.000	0.968	0.032
F63 Habit and impulse disorders	0.000	0.968	0.032
F68 Other disorders of adult personality and behaviour	0.000	0.969	0.030
E53.1 Pyridoxine deficiency	0.030	0.970	0.000
E53.0 Riboflavin deficiency	0.030	0.970	0.000
F69 Unspecified disorder of adult personality and behaviour	0.000	0.970	0.030
F64.0 Transsexualism	0.000	0.971	0.029
E21.0 Primary hyperparathyroidism	0.027	0.973	0.000
E53.8 Deficiency of other specified B group vitamins	0.027	0.973	0.000
F62.9 Enduring personality change, unspecified	0.000	0.974	0.025
F64.9 Gender identity disorder, unspecified	0.000	0.974	0.025
F64.8 Other gender identity disorders	0.000	0.974	0.025
F64.2 Gender identity disorder of childhood	0.000	0.974	0.025
F64.1 Dual-role transvestism	0.000	0.974	0.025
E53.9 Vitamin B deficiency, unspecified	0.024	0.976	0.000
E56.1 Deficiency of vitamin K	0.023	0.976	0.001
F62.8 Other enduring personality changes	0.000	0.976	0.024
F62.1 Enduring personality change after psychiatric illness	0.000	0.976	0.024
F62.0 Enduring personality change after catastrophic experience	0.000	0.976	0.024
E55.0 Rickets, active	0.024	0.976	0.000
X62.0 Home	0.000	0.977	0.023
X62.7 Farm	0.000	0.977	0.023
X62.6 Industrial and construction area	0.000	0.977	0.023
X62.5 Trade and service area	0.000	0.977	0.023
X62.4 Street and highway	0.000	0.977	0.023
X62.3 Sports and athletics area	0.000	0.977	0.023
X62.2 School, other institution and public administrative area	0.000	0.977	0.023
X62.1 Residential institution	0.000	0.977	0.023
F63.9 Habit and impulse disorder, unspecified	0.000	0.977	0.023
F63.8 Other habit and impulse disorders	0.000	0.977	0.023
F63.3 Trichotillomania	0.000	0.977	0.023
F63.2 Pathological stealing [kleptomania]	0.000	0.977	0.023
F63.1 Pathological fire-setting [pyromania]	0.000	0.977	0.023
F63.0 Pathological gambling	0.000	0.977	0.023
F65.9 Disorder of sexual preference, unspecified	0.000	0.977	0.023
F65.8 Other disorders of sexual preference	0.000	0.977	0.023
F65.6 Multiple disorders of sexual preference	0.000	0.977	0.023
F65.5 Sadomasochism	0.000	0.977	0.023
F65.4 Paedophilia	0.000	0.977	0.023
F65.3 Voyeurism	0.000	0.977	0.023
F65.2 Exhibitionism	0.000	0.977	0.023
F65.1 Fetishistic transvestism	0.000	0.977	0.023
F65.0 Fetishism	0.000	0.977	0.023
F66.9 Psychosexual development disorder, unspecified	0.000	0.977	0.023
F66.8 Other psychosexual development disorders	0.000	0.977	0.023
F66.2 Sexual relationship disorder	0.000	0.977	0.023
F66.1 Egodystonic sexual orientation	0.000	0.977	0.023
F66.0 Sexual maturation disorder	0.000	0.977	0.023
E10-E14 Diabetes mellitus	0.023	0.977	0.000
T40.2 Other opioids	0.000	0.978	0.022
F68.8 Other specified disorders of adult personality and behaviour	0.000	0.978	0.022
F68.0 Elaboration of physical symptoms for psychological reasons	0.000	0.978	0.022
X62.8 Other specified place	0.000	0.978	0.022
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.000	0.979	0.021
E80.4 Gilbert's syndrome	0.020	0.980	0.000
G81.9 Hemiplegia, unspecified	0.020	0.980	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.000	0.983	0.017
E12 Malnutrition-related diabetes mellitus	0.016	0.983	0.000
Z48 Other surgical follow-up care	0.016	0.984	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.984	0.016
K83.8 Other specified diseases of biliary tract	0.015	0.985	0.000
X60-X84 Intentional self-harm	0.000	0.986	0.014
E13 Other specified diabetes mellitus	0.014	0.986	0.000
E66 Obesity	0.014	0.986	0.000
Z48.0 Attention to surgical dressings and sutures	0.013	0.987	0.000
E14 Unspecified diabetes mellitus	0.013	0.987	0.000
T40.4 Other synthetic narcotics	0.000	0.987	0.013
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.987	0.013
E12.9 Without complications	0.012	0.988	0.000
E12.8 With unspecified complications	0.012	0.988	0.000
E12.7 With multiple complications	0.012	0.988	0.000
E12.6 With other specified complications	0.012	0.988	0.000
E12.5 With peripheral circulatory complications	0.012	0.988	0.000
E12.4 With neurological complications	0.012	0.988	0.000
E12.3 With ophthalmic complications	0.012	0.988	0.000
E12.2 With renal complications	0.012	0.988	0.000
E12.1 With ketoacidosis	0.012	0.988	0.000
E12.0 With coma	0.012	0.988	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.000	0.988	0.012
E83 Disorders of mineral metabolism	0.012	0.988	0.000
T40.1 Heroin	0.000	0.988	0.012
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.988	0.012
T40.5 Cocaine	0.000	0.988	0.012
T40.3 Methadone	0.000	0.988	0.012
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.000	0.988	0.012
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.988	0.011
T40.8 Lysergide [LSD]	0.000	0.988	0.011
T40.7 Cannabis (derivatives)	0.000	0.988	0.011
T40.0 Opium	0.000	0.988	0.011
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.988	0.012
E14.3 With ophthalmic complications	0.011	0.989	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.000	0.989	0.011
E14.2 Withrenal complications	0.011	0.989	0.000
G81 Hemiplegia	0.011	0.989	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.989	0.011
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.989	0.011
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.989	0.011
X63.0 Home	0.000	0.989	0.011
X70 Intentional self-harm by hanging, strangulation and suffocation	0.000	0.989	0.010
E13.3 With ophthalmic complications	0.010	0.989	0.000
E14.8 With unspecified complications	0.010	0.990	0.000
X84 Intentional self-harm by unspecified means	0.000	0.990	0.010
X83 Intentional self-harm by other specified means	0.000	0.990	0.010
X82 Intentional self-harm by crashing of motor vehicle	0.000	0.990	0.010
X81 Intentional self-harm by jumping or lying before moving object	0.000	0.990	0.010
X80 Intentional self-harm by jumping from a high place	0.000	0.990	0.010
X79 Intentional self-harm by blunt object	0.000	0.990	0.010
X77 Intentional self-harm by steam, hot vapours and hot objects	0.000	0.990	0.010
X76 Intentional self-harm by smoke, fire and flames	0.000	0.990	0.010
X75 Intentional self-harm by explosive material	0.000	0.990	0.010
X74 Intentional self-harm by other and unspecified firearm discharge	0.000	0.990	0.010
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.000	0.990	0.010
X72 Intentional self-harm by handgun discharge	0.000	0.990	0.010
X71 Intentional self-harm by drowning and submersion	0.000	0.990	0.010
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.000	0.990	0.010
E13.8 With unspecified complications	0.010	0.990	0.000
E13.7 With multiple complications	0.010	0.990	0.000
E13.6 With other specified complications	0.010	0.990	0.000
E13.5 With peripheral circulatory complications	0.010	0.990	0.000
E13.4 With neurological complications	0.010	0.990	0.000
E13.2 With renal complications	0.010	0.990	0.000
E13.1 With ketoacidosis	0.010	0.990	0.000
E13.0 With coma	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.990	0.010
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.010	0.990	0.000
E14.6 With other specified complications	0.010	0.990	0.000
T42.1 Iminostilbenes	0.000	0.990	0.010
E66.1 Drug-induced obesity	0.010	0.990	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.000	0.990	0.010
X65 Intentional self-poisoning by and exposure to alcohol	0.000	0.990	0.010
E14.0 With coma	0.010	0.990	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.010	0.990	0.000
E14.1 With ketoacidosis	0.010	0.990	0.000
E14.7 With multiple complications	0.010	0.990	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.000	0.990	0.010
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.000	0.990	0.010
E66.0 Obesity due to excess calories	0.009	0.990	0.000
X60.8 Other specified place	0.000	0.990	0.009
T42.0 Hydantoin derivatives	0.000	0.991	0.009
E78.1 Pure hyperglyceridaemia	0.009	0.991	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.991	0.009
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.991	0.009
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.991	0.009
X63.9 Unspecified place	0.000	0.991	0.009
X63.8 Other specified place	0.000	0.991	0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations