TreeWAS – Variant ID: rs1449984

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.962	0.038	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.958	0.042	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.954	0.046	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.944	0.056	0.000
T39.1 4-Aminophenol derivatives	0.922	0.078	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.922	0.078	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.919	0.081	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.901	0.099	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.892	0.108	0.000
T40.4 Other synthetic narcotics	0.885	0.115	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.851	0.149	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.843	0.157	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.816	0.184	0.000
T36 Poisoning by systemic antibiotics	0.807	0.193	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.780	0.220	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.776	0.224	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.773	0.227	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.763	0.237	0.000
T50.4 Drugs affecting uric acid metabolism	0.759	0.241	0.000
T40.5 Cocaine	0.748	0.252	0.000
T40.6 Other and unspecified narcotics	0.746	0.254	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.730	0.270	0.000
T43.9 Psychotropic drug, unspecified	0.728	0.272	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.710	0.290	0.000
T36.0 Penicillins	0.696	0.304	0.000
T42.1 Iminostilbenes	0.691	0.309	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.690	0.310	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.690	0.310	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.687	0.313	0.000
T39.4 Antirheumatics, not elsewhere classified	0.684	0.316	0.000
T39.2 Pyrazolone derivatives	0.684	0.316	0.000
T40.1 Heroin	0.679	0.321	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.675	0.325	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.673	0.327	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.672	0.327	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.659	0.341	0.000
T40.8 Lysergide [LSD]	0.659	0.341	0.000
T40.7 Cannabis (derivatives)	0.659	0.341	0.000
T40.3 Methadone	0.659	0.341	0.000
T40.0 Opium	0.659	0.341	0.000
T43.6 Psychostimulants with abuse potential	0.657	0.343	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.652	0.348	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.650	0.350	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.648	0.352	0.000
T50.7 Analeptics and opioid receptor antagonists	0.646	0.354	0.000
T50.5 Appetite depressants	0.646	0.354	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.646	0.354	0.000
T50.1 Loop [high-ceiling] diuretics	0.646	0.354	0.000
T50.0 Mineralocorticoids and their antagonists	0.646	0.354	0.000
T50.8 Diagnostic agents	0.645	0.354	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.644	0.356	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.644	0.356	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.638	0.362	0.000
T42.3 Barbiturates	0.625	0.375	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.616	0.384	0.000
T39.0 Salicylates	0.609	0.391	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.605	0.395	0.000
T42.2 Succinimides and oxazolidinediones	0.605	0.395	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.602	0.398	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.599	0.401	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.585	0.415	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.585	0.415	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.585	0.415	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.585	0.415	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.585	0.415	0.000
T44.0 Anticholinesterase agents	0.585	0.415	0.000
T47.4 Other laxatives	0.584	0.416	0.000
T36.9 Systemic antibiotic, unspecified	0.579	0.421	0.000
T36.8 Other systemic antibiotics	0.579	0.421	0.000
T36.7 Antifungal antibiotics, systemically used	0.579	0.421	0.000
T36.6 Rifamycins	0.579	0.421	0.000
T36.5 Aminoglycosides	0.579	0.421	0.000
T36.4 Tetracyclines	0.579	0.421	0.000
T36.3 Macrolides	0.579	0.421	0.000
T36.2 Chloramphenicol group	0.579	0.421	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.579	0.421	0.000
T42.0 Hydantoin derivatives	0.565	0.435	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.563	0.437	0.000
T49.9 Topical agent, unspecified	0.554	0.446	0.000
T49.8 Other topical agents	0.554	0.446	0.000
T49.7 Dental drugs, topically applied	0.554	0.446	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.554	0.446	0.000
T49.5 Ophthalmological drugs and preparations	0.554	0.446	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.554	0.446	0.000
T49.3 Emollients, demulcents and protectants	0.554	0.446	0.000
T49.2 Local astringents and local detergents	0.554	0.446	0.000
T49.1 Antipruritics	0.554	0.446	0.000
T45.5 Anticoagulants	0.534	0.466	0.000
T47.2 Stimulant laxatives	0.526	0.474	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.523	0.477	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.523	0.477	0.000
T47.7 Emetics	0.523	0.477	0.000
T47.6 Antidiarrhoeal drugs	0.523	0.477	0.000
T47.5 Digestants	0.523	0.477	0.000
T47.3 Saline and osmotic laxatives	0.523	0.477	0.000
T47.0 Histamine H(2)-receptor antagonists	0.523	0.477	0.000
T38.0 Glucocorticoids and synthetic analogues	0.507	0.493	0.000
T41.5 Therapeutic gases	0.495	0.505	0.000
T41.4 Anaesthetic, unspecified	0.495	0.505	0.000
T41.3 Local anaesthetics	0.495	0.505	0.000
T41.2 Other and unspecified general anaesthetics	0.495	0.505	0.000
T41.1 Intravenous anaesthetics	0.495	0.505	0.000
T41.0 Inhaled anaesthetics	0.495	0.505	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.495	0.505	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.495	0.505	0.000
T48.5 Anti-common-cold drugs	0.495	0.505	0.000
T48.4 Expectorants	0.495	0.505	0.000
T48.3 Antitussives	0.495	0.505	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.495	0.505	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.495	0.505	0.000
T48.0 Oxytocic drugs	0.495	0.505	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.490	0.510	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.490	0.510	0.000
T38.9 Other and unspecified hormone antagonists	0.468	0.532	0.000
T38.7 Androgens and anabolic congeners	0.468	0.532	0.000
T38.5 Other oestrogens and progestogens	0.468	0.532	0.000
T38.4 Oral contraceptives	0.468	0.532	0.000
T38.2 Antithyroid drugs	0.468	0.532	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.462	0.538	0.000
T37.5 Antiviral drugs	0.462	0.538	0.000
T37.4 Anthelminthics	0.462	0.538	0.000
T37.3 Other antiprotozoal drugs	0.462	0.538	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.462	0.538	0.000
T37.1 Antimycobacterial drugs	0.462	0.538	0.000
T37.0 Sulphonamides	0.462	0.538	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.452	0.548	0.000
T38.1 Thyroid hormones and substitutes	0.446	0.554	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.443	0.557	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.442	0.558	0.000
T45.8 Other primarily systemic and haematological agents	0.442	0.558	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.442	0.558	0.000
T45.6 Fibrinolysis-affecting drugs	0.442	0.558	0.000
T45.4 Iron and its compounds	0.442	0.558	0.000
T45.3 Enzymes, not elsewhere classified	0.442	0.558	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.438	0.562	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.416	0.584	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.399	0.601	0.000
T45.0 Antiallergic and antiemetic drugs	0.395	0.605	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.365	0.634	0.000
T40.2 Other opioids	0.344	0.656	0.000
T45.2 Vitamins, not elsewhere classified	0.325	0.675	0.001
T43.2 Other and unspecified antidepressants	0.318	0.682	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.314	0.686	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.314	0.686	0.000
T46.7 Peripheral vasodilators	0.314	0.686	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.314	0.686	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.314	0.686	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.312	0.687	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.307	0.693	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.306	0.694	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.238	0.761	0.000
T46.1 Calcium-channel blockers	0.235	0.765	0.000
T42.4 Benzodiazepines	0.192	0.808	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.016	0.984	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.985	0.015
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.986	0.014
N13.8 Other obstructive and reflux uropathy	0.000	0.988	0.012
N13 Obstructive and reflux uropathy	0.000	0.988	0.012
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.010	0.990	0.000
N13.4 Hydroureter	0.000	0.990	0.010
I70.2 Atherosclerosis of arteries of the extremities	0.010	0.990	0.000
E87.0 Hyperosmolality and hypernatraemia	0.010	0.990	0.000
N13.6 Pyonephrosis	0.000	0.990	0.010
H52.2 Astigmatism	0.000	0.990	0.010
F20.9 Schizophrenia, unspecified	0.009	0.991	0.000
F20.0 Paranoid schizophrenia	0.009	0.991	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.009	0.991	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.992	0.008
F20 Schizophrenia	0.008	0.992	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.992	0.008
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.992	0.008
D45 Polycythaemia vera	0.000	0.992	0.008
S62.61 Fracture of other finger (open)	0.008	0.992	0.000
S82.20 Fracture of shaft of tibia (closed)	0.007	0.993	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.007	0.993	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.993	0.006
S62.40 Multiple fractures of metacarpal bones (closed)	0.006	0.994	0.000
F20.8 Other schizophrenia	0.006	0.994	0.000
F20.6 Simple schizophrenia	0.006	0.994	0.000
F20.4 Postschizophrenic depression	0.006	0.994	0.000
F20.3 Undifferentiated schizophrenia	0.006	0.994	0.000
F20.2 Catatonic schizophrenia	0.006	0.994	0.000
F20.1 Hebephrenic schizophrenia	0.006	0.994	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.006	0.994	0.000
F20.5 Residual schizophrenia	0.005	0.994	0.000
G90.2 Horner's syndrome	0.005	0.995	0.000
S62.4 Multiple fractures of metacarpal bones	0.005	0.995	0.000
G71.1 Myotonic disorders	0.005	0.995	0.000
H52 Disorders of refraction and accommodation	0.000	0.995	0.005
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.995	0.004
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
S62.6 Fracture of other finger	0.004	0.996	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.004	0.996	0.000
M47.9 Spondylosis, unspecified	0.004	0.996	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.996	0.004
N13.3 Other and unspecified hydronephrosis	0.000	0.996	0.004
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.996	0.004
H44.2 Degenerative myopia	0.000	0.996	0.004
Q23.1 Congenital insufficiency of aortic valve	0.000	0.996	0.004
G90.0 Idiopathic peripheral autonomic neuropathy	0.004	0.996	0.000
H33.5 Other retinal detachments	0.004	0.996	0.000
G90 Disorders of autonomic nervous system	0.004	0.996	0.000
H52.0 Hypermetropia	0.000	0.996	0.004
T92.1 Sequelae of fracture of arm	0.004	0.996	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.004	0.996	0.000
S62 Fracture at wrist and hand level	0.004	0.996	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.996	0.004
M47.96 Spondylosis, unspecified (Lumbar region)	0.004	0.996	0.000
E23.0 Hypopituitarism	0.000	0.996	0.004
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.004	0.996	0.000
H52.6 Other disorders of refraction	0.000	0.996	0.003
H52.5 Disorders of accommodation	0.000	0.996	0.003
H52.4 Presbyopia	0.000	0.996	0.003
O72.0 Third-stage haemorrhage	0.003	0.996	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.003	0.997	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.003	0.997	0.000
G61.8 Other inflammatory polyneuropathies	0.003	0.997	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
I70 Atherosclerosis	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
K25.7 Chronic without haemorrhage or perforation	0.000	0.997	0.003
R22.1 Localised swelling, mass and lump, neck	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.997	0.003
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.003	0.997	0.000
G90.4 Autonomic dysreflexia	0.003	0.997	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.003	0.997	0.000
G90.8 Other disorders of autonomic nervous system	0.003	0.997	0.000
G90.3 Multisystem degeneration	0.003	0.997	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.997	0.003
R22.3 Localised swelling, mass and lump, upper limb	0.003	0.997	0.000
M95.0 Acquired deformity of nose	0.003	0.997	0.000
G71 Primary disorders of muscles	0.003	0.997	0.000
H44 Disorders of globe	0.000	0.997	0.003
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
H44.4 Hypotony of eye	0.000	0.997	0.003
R22.9 Localised swelling, mass and lump, unspecified	0.003	0.997	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.997	0.003
K57.2 Diverticular disease of large intestine with perforation and abscess	0.003	0.997	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
R22.0 Localised swelling, mass and lump, head	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.000	0.997	0.003
M25.54 Pain in joint (Hand)	0.003	0.997	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.997	0.003
I70.8 Atherosclerosis of other arteries	0.002	0.997	0.000
S62.7 Multiple fractures of fingers	0.002	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
G71.3 Mitochondrial myopathy, not elsewhere classified	0.003	0.997	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.002	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.997	0.000
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
N99.5 Malfunction of external stoma of urinary tract	0.000	0.997	0.002
T17.2 Foreign body in pharynx	0.003	0.997	0.000
D03 Melanoma in situ	0.003	0.997	0.000
H44.9 Disorder of globe, unspecified	0.000	0.997	0.002
R22.2 Localised swelling, mass and lump, trunk	0.002	0.997	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.002	0.998	0.000
H44.5 Degenerated conditions of globe	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.002
H44.3 Other degenerative disorders of globe	0.000	0.998	0.002
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
H44.1 Other endophthalmitis	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
H44.8 Other disorders of globe	0.000	0.998	0.002
J15.5 Pneumonia due to Escherichia coli	0.000	0.998	0.002
N50.9 Disorder of male genital organs, unspecified	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M95.1 Cauliflower ear	0.002	0.998	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.002	0.998	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.000	0.998	0.002
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.998	0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.002
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
F25 Schizoaffective disorders	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.002	0.998	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
T56.8 Other metals	0.002	0.998	0.000
H43 Disorders of vitreous body	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
E78.8 Other disorders of lipoprotein metabolism	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.000	0.998	0.002
Z92.0 Personal history of contraception	0.000	0.998	0.002
T17 Foreign body in respiratory tract	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
T00.9 Multiple superficial injuries, unspecified	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
S62.5 Fracture of thumb	0.001	0.998	0.001
T17.3 Foreign body in larynx	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.000	0.998	0.002
A41 Other septicaemia	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
H44.0 Purulent endophthalmitis	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
F84.5 Asperger's syndrome	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
T75.4 Effects of electric current	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
A41.4 Septicaemia due to anaerobes	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
F84.0 Childhood autism	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
F84 Pervasive developmental disorders	0.002	0.998	0.000
T56 Toxic effect of metals	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
K51.5 Mucosal proctocolitis	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
H43.9 Disorder of vitreous body, unspecified	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
N50 Other disorders of male genital organs	0.000	0.998	0.002
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
T19 Foreign body in genito-urinary tract	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
T17.4 Foreign body in trachea	0.001	0.998	0.000
T17.1 Foreign body in nostril	0.001	0.998	0.000
T17.0 Foreign body in nasal sinus	0.001	0.998	0.000
T19.0 Foreign body in urethra	0.002	0.998	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.998	0.001
S02.61 Fracture of mandible (open)	0.001	0.998	0.000
A87.2 Lymphocytic choriomeningitis	0.002	0.998	0.000
T62.9 Noxious substance eaten as food, unspecified	0.002	0.998	0.000
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.000	0.998	0.001
T19.2 Foreign body in vulva and vagina	0.001	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.998	0.002
N50.0 Atrophy of testis	0.000	0.998	0.002
U51 Admission status on psychiatric patients	0.002	0.998	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.001	0.998	0.000
F52.0 Lack or loss of sexual desire	0.001	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.001
N71.1 Chronic inflammatory disease of uterus	0.000	0.998	0.002
S65.0 Injury of ulnar artery at wrist and hand level	0.001	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.998	0.000
T00 Superficial injuries involving multiple body regions	0.001	0.998	0.000
T62 Toxic effect of other noxious substances eaten as food	0.001	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.001	0.998	0.000
T52.8 Other organic solvents	0.001	0.998	0.000
A87 Viral meningitis	0.001	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.998	0.000
F84.9 Pervasive developmental disorder, unspecified	0.001	0.998	0.000
F84.8 Other pervasive developmental disorders	0.001	0.998	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.001	0.998	0.000
F84.3 Other childhood disintegrative disorder	0.001	0.998	0.000
F84.2 Rett's syndrome	0.001	0.998	0.000
F84.1 Atypical autism	0.001	0.998	0.000
S65.1 Injury of radial artery at wrist and hand level	0.001	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations