TreeWAS – Variant ID: rs1460196

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.924	0.076
M48.06 Spinal stenosis (Lumbar region)	0.000	0.959	0.041
M48.0 Spinal stenosis	0.000	0.963	0.037
M48.02 Spinal stenosis (Cervical region)	0.000	0.965	0.035
M48.09 Spinal stenosis (Site unspecified)	0.000	0.969	0.031
Z51.2 Other chemotherapy	0.000	0.970	0.030
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.973	0.027
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.973	0.027
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.973	0.027
M48.04 Spinal stenosis (Thoracic region)	0.000	0.973	0.027
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.973	0.027
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.973	0.027
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.974	0.026
M48 Other spondylopathies	0.000	0.984	0.016
M48.9 Spondylopathy, unspecified	0.000	0.988	0.012
M48.8 Other specified spondylopathies	0.000	0.988	0.012
M48.4 Fatigue fracture of vertebra	0.000	0.988	0.012
M48.3 Traumatic spondylopathy	0.000	0.988	0.012
M48.2 Kissing spine	0.000	0.988	0.012
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.988	0.012
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.988	0.011
R10.3 Pain localised to other parts of lower abdomen	0.000	0.989	0.011
J18.1 Lobar pneumonia, unspecified	0.011	0.989	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.991	0.009
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.991	0.009
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.991	0.009
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.991	0.009
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.991	0.009
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.991	0.009
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.991	0.009
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.991	0.009
M48.29 Kissing spine (Site unspecified)	0.000	0.991	0.009
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.27 Kissing spine (Lumbosacral region)	0.000	0.991	0.009
M48.26 Kissing spine (Lumbar region)	0.000	0.991	0.009
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.991	0.009
M48.24 Kissing spine (Thoracic region)	0.000	0.991	0.009
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.991	0.009
M48.22 Kissing spine (Cervical region)	0.000	0.991	0.009
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.991	0.009
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.991	0.009
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.991	0.009
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.991	0.009
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.991	0.009
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.991	0.009
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.991	0.009
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.991	0.009
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.991	0.009
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.991	0.009
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.991	0.009
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.991	0.009
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.991	0.009
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.991	0.009
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.991	0.009
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.991	0.009
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.991	0.009
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.991	0.009
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.991	0.009
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.991	0.009
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.991	0.009
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.991	0.009
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.991	0.009
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.991	0.009
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.991	0.009
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.991	0.009
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.991	0.009
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.991	0.009
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.991	0.009
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.991	0.009
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.991	0.009
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.991	0.009
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.991	0.009
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.991	0.009
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.991	0.008
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.991	0.008
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.991	0.008
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.991	0.008
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.991	0.008
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.991	0.008
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.991	0.008
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.991	0.008
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.991	0.008
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.992	0.008
Z80.3 Family history of malignant neoplasm of breast	0.008	0.992	0.000
R14 Flatulence and related conditions	0.000	0.994	0.006
Z80 Family history of malignant neoplasm	0.006	0.994	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.006	0.994	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.005	0.994	0.000
R11 Nausea and vomiting	0.000	0.995	0.005
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.005	0.995	0.000
J18 Pneumonia, organism unspecified	0.005	0.995	0.000
R10 Abdominal and pelvic pain	0.000	0.995	0.005
Z80.4 Family history of malignant neoplasm of genital organs	0.005	0.995	0.000
J18.0 Bronchopneumonia, unspecified	0.005	0.995	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.004	0.996	0.000
Z80.6 Family history of leukaemia	0.004	0.996	0.000
R10.2 Pelvic and perineal pain	0.000	0.996	0.004
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.004	0.996	0.000
D22.5 Melanocytic naevi of trunk	0.004	0.996	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.000	0.996	0.004
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
J18.8 Other pneumonia, organism unspecified	0.004	0.996	0.000
J18.2 Hypostatic pneumonia, unspecified	0.004	0.996	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.004	0.996	0.000
K35.9 Acute appendicitis, unspecified	0.004	0.996	0.000
R10.0 Acute abdomen	0.000	0.996	0.004
N35.9 Urethral stricture, unspecified	0.000	0.996	0.004
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
D22 Melanocytic naevi	0.003	0.997	0.000
R18 Ascites	0.000	0.997	0.003
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.997	0.003
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.003	0.997	0.000
O66 Other obstructed labour	0.003	0.997	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.003	0.997	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
O63 Long labour	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
R17 Unspecified jaundice	0.000	0.997	0.003
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
Z80.8 Family history of malignant neoplasm of other organs or systems	0.003	0.997	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.003	0.997	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.003	0.997	0.000
D22.0 Melanocytic naevi of lip	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
D22.9 Melanocytic naevi, unspecified	0.003	0.997	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.000	0.997	0.003
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
D22.4 Melanocytic naevi of scalp and neck	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
H26.9 Cataract, unspecified	0.003	0.997	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
K35 Acute appendicitis	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.997	0.000
Y51.0 Anticholinesterase agents	0.002	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.997	0.002
M45-M49 Spondylopathies	0.000	0.997	0.003
N35 Urethral stricture	0.000	0.997	0.003
O63.9 Long labour, unspecified	0.002	0.997	0.000
O66.9 Obstructed labour, unspecified	0.002	0.997	0.000
O66.8 Other specified obstructed labour	0.002	0.997	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.997	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.997	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.997	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.997	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.002	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.997	0.000
Y58 Bacterial vaccines	0.002	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.997	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.997	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.997	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
N32.8 Other specified disorders of bladder	0.000	0.998	0.002
R10.4 Other and unspecified abdominal pain	0.000	0.998	0.002
O71 Other obstetric trauma	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
N32 Other disorders of bladder	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.998	0.002
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
N32.3 Diverticulum of bladder	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
O74 Complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.002	0.998	0.000
O60 Preterm delivery	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
M19.9 Arthrosis, unspecified	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
N35.8 Other urethral stricture	0.000	0.998	0.002
N35.1 Postinfective urethral stricture, not elsewhere classified	0.000	0.998	0.002
N35.0 Posttraumatic urethral stricture	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
R15 Faecal incontinence	0.000	0.998	0.002
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.998	0.002
O61 Failed induction of labour	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.002	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.998	0.000
O64.3 Obstructed labour due to brow presentation	0.002	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.002	0.998	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
O62 Abnormalities of forces of labour	0.002	0.998	0.000
R06.0 Dyspnoea	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
M49 Spondylopathies in diseases classified elsewhere	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
O73 Retained placenta and membranes, without haemorrhage	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.998	0.000
O71.7 Obstetric haematoma of pelvis	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.998	0.000
O71.5 Other obstetric injury to pelvic organs	0.002	0.998	0.000
O71.3 Obstetric laceration of cervix	0.002	0.998	0.000
O71.2 Postpartum inversion of uterus	0.002	0.998	0.000
O71.1 Rupture of uterus during labour	0.002	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
N36 Other disorders of urethra	0.000	0.998	0.002
N32.4 Rupture of bladder, nontraumatic	0.000	0.998	0.002
N32.2 Vesical fistula, not elsewhere classified	0.000	0.998	0.002
N39.8 Other specified disorders of urinary system	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
S52.50 Fracture of lower end of radius (closed)	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
S52.5 Fracture of lower end of radius	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
S52 Fracture of forearm	0.002	0.998	0.000
N36.2 Urethral caruncle	0.000	0.998	0.002
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
O60.3 Preterm delivery without spontaneous labour	0.002	0.998	0.000
O60.2 Preterm spontaneous labour with term delivery	0.002	0.998	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.002	0.998	0.000
O60.0 Preterm labour without delivery	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.002	0.998	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.002	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.002	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.998	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.002	0.998	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.002	0.998	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.002	0.998	0.000
O65.0 Obstructed labour due to deformed pelvis	0.002	0.998	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.002	0.998	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.002	0.998	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.002	0.998	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.002	0.998	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.002	0.998	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
J09-J18 Influenza and pneumonia	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
E14.9 Without complications	0.002	0.998	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.998	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.998	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.998	0.002
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
Z12.1 Special screening examination for neoplasm of intestinal tract	0.002	0.998	0.000
H26.1 Traumatic cataract	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.002
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
O61.8 Other failed induction of labour	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
O62.1 Secondary uterine inertia	0.002	0.998	0.000
O67.8 Other intrapartum haemorrhage	0.002	0.998	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
M46 Other inflammatory spondylopathies	0.001	0.998	0.001
N30-N39 Other diseases of urinary system	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations