TreeWAS – Variant ID: rs1468758

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H74 Other disorders of middle ear and mastoid	0.000	0.921	0.079
H65-H75 Diseases of middle ear and mastoid	0.000	0.925	0.075
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.927	0.073
H74.4 Polyp of middle ear	0.000	0.927	0.073
H71 Cholesteatoma of middle ear	0.000	0.927	0.073
H74.1 Adhesive middle ear disease	0.000	0.935	0.065
H69 Other disorders of Eustachian tube	0.000	0.936	0.064
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.936	0.064
H73 Other disorders of tympanic membrane	0.000	0.936	0.064
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.937	0.063
H65 Nonsuppurative otitis media	0.000	0.937	0.063
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.940	0.060
H65.3 Chronic mucoid otitis media	0.000	0.943	0.057
H74.0 Tympanosclerosis	0.000	0.944	0.056
H69.9 Eustachian tube disorder, unspecified	0.000	0.946	0.054
H66 Suppurative and unspecified otitis media	0.000	0.946	0.054
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.946	0.054
H68 Eustachian salpingitis and obstruction	0.000	0.946	0.054
H67 Otitis media in diseases classified elsewhere	0.000	0.946	0.054
H73.8 Other specified disorders of tympanic membrane	0.000	0.947	0.053
H65.0 Acute serous otitis media	0.000	0.948	0.052
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.949	0.051
H69.8 Other specified disorders of Eustachian tube	0.000	0.949	0.051
H65.4 Other chronic nonsuppurative otitis media	0.000	0.952	0.048
H66.9 Otitis media, unspecified	0.000	0.953	0.047
H69.0 Patulous Eustachian tube	0.000	0.954	0.046
H73.1 Chronic myringitis	0.000	0.954	0.046
H73.0 Acute myringitis	0.000	0.954	0.046
H70 Mastoiditis and related conditions	0.000	0.956	0.044
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.958	0.042
H66.0 Acute suppurative otitis media	0.000	0.959	0.041
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.959	0.041
H65.1 Other acute nonsuppurative otitis media	0.000	0.960	0.039
H72 Perforation of tympanic membrane	0.000	0.960	0.040
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.961	0.039
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.961	0.039
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.961	0.039
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.961	0.039
H68.1 Obstruction of Eustachian tube	0.000	0.961	0.039
H68.0 Eustachian salpingitis	0.000	0.961	0.039
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.961	0.039
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.961	0.039
H65.2 Chronic serous otitis media	0.000	0.963	0.037
N13.4 Hydroureter	0.037	0.963	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.964	0.036
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.035	0.965	0.000
N13 Obstructive and reflux uropathy	0.034	0.966	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.968	0.032
H70.2 Petrositis	0.000	0.968	0.032
H70.1 Chronic mastoiditis	0.000	0.968	0.032
H70.0 Acute mastoiditis	0.000	0.968	0.032
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.031	0.969	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.031	0.969	0.000
S82.40 Fracture of fibula alone (closed)	0.030	0.970	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.029	0.971	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.972	0.028
Z88.5 Personal history of allergy to narcotic agent	0.028	0.972	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.973	0.027
N13.7 Vesicoureteral-reflux-associated uropathy	0.026	0.974	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.974	0.026
H72.2 Other marginal perforations of tympanic membrane	0.000	0.974	0.026
N13.8 Other obstructive and reflux uropathy	0.025	0.975	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.975	0.025
N13.6 Pyonephrosis	0.023	0.977	0.000
H70.9 Mastoiditis, unspecified	0.000	0.978	0.022
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.021	0.979	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.983	0.017
N86 Erosion and ectropion of cervix uteri	0.016	0.984	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.985	0.015
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.985	0.015
L92.0 Granuloma annulare	0.000	0.986	0.014
S82.4 Fracture of fibula alone	0.013	0.987	0.000
Y40.8 Other systemic antibiotics	0.012	0.988	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.988	0.012
N10-N16 Renal tubulo-interstitial diseases	0.012	0.988	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.989	0.011
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.989	0.011
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.990	0.010
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.010	0.990	0.000
N83.0 Follicular cyst of ovary	0.010	0.990	0.000
N15 Other renal tubulo-interstitial diseases	0.009	0.990	0.000
N83.1 Corpus luteum cyst	0.010	0.990	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.991	0.009
S82.41 Fracture of fibula alone (open)	0.009	0.991	0.000
N10 Acute tubulo-interstitial nephritis	0.009	0.991	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.009	0.991	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.009	0.991	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.009	0.991	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.009	0.991	0.000
N80.9 Endometriosis, unspecified	0.000	0.992	0.008
N13.3 Other and unspecified hydronephrosis	0.008	0.992	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.008	0.992	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.008	0.992	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.992	0.008
N14.4 Toxic nephropathy, not elsewhere classified	0.007	0.992	0.000
N14.3 Nephropathy induced by heavy metals	0.007	0.992	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.007	0.992	0.000
N14.0 Analgesic nephropathy	0.007	0.992	0.000
N11 Chronic tubulo-interstitial nephritis	0.007	0.993	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.007	0.993	0.000
N83.6 Haematosalpinx	0.007	0.993	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.007	0.993	0.000
N15.0 Balkan nephropathy	0.007	0.993	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.007	0.993	0.000
N15.1 Renal and perinephric abscess	0.007	0.993	0.000
I67.9 Cerebrovascular disease, unspecified	0.007	0.993	0.000
R25.1 Tremor, unspecified	0.007	0.993	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.006	0.993	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.006	0.993	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.006	0.993	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.006	0.993	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.006	0.993	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.006	0.993	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
N83.7 Haematoma of broad ligament	0.006	0.993	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.006	0.993	0.000
R25.2 Cramp and spasm	0.007	0.993	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.006	0.994	0.000
R25 Abnormal involuntary movements	0.006	0.994	0.000
K37 Unspecified appendicitis	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
I67 Other cerebrovascular diseases	0.006	0.994	0.000
Q21.1 Atrial septal defect	0.006	0.994	0.000
I67.1 Cerebral aneurysm, nonruptured	0.006	0.994	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.005	0.994	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.005	0.994	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.005	0.995	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.995	0.005
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
N11.1 Chronic obstructive pyelonephritis	0.005	0.995	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.995	0.005
I67.8 Other specified cerebrovascular diseases	0.005	0.995	0.000
L08 Other local infections of skin and subcutaneous tissue	0.005	0.995	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
R25.3 Fasciculation	0.005	0.995	0.000
I89.0 Lymphoedema, not elsewhere classified	0.005	0.995	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.995	0.005
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.004	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.995	0.000
Q50.5 Embryonic cyst of broad ligament	0.004	0.995	0.000
R25.0 Abnormal head movements	0.004	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.004	0.996	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.004	0.996	0.000
I67.5 Moyamoya disease	0.004	0.996	0.000
I67.4 Hypertensive encephalopathy	0.004	0.996	0.000
I67.3 Progressive vascular leukoencephalopathy	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
L08.0 Pyoderma	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
I67.2 Cerebral atherosclerosis	0.004	0.996	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.996	0.000
Q50.2 Congenital torsion of ovary	0.004	0.996	0.000
Q50.1 Developmental ovarian cyst	0.004	0.996	0.000
Q50.0 Congenital absence of ovary	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
J00 Acute nasopharyngitis [common cold]	0.004	0.996	0.000
T40.2 Other opioids	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.996	0.001
L08.1 Erythrasma	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.996	0.000
Q25.3 Stenosis of aorta	0.003	0.996	0.000
Q25.2 Atresia of aorta	0.003	0.996	0.000
Q25.0 Patent ductus arteriosus	0.003	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.996	0.003
G04.1 Tropical spastic paraplegia	0.000	0.996	0.003
G04.0 Acute disseminated encephalitis	0.000	0.996	0.003
Q96.9 Turner's syndrome, unspecified	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.996	0.000
I73.9 Peripheral vascular disease, unspecified	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.003	0.997	0.000
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.997	0.003
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.997	0.003
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
G62 Other polyneuropathies	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.997	0.003
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q96.8 Other variants of Turner's syndrome	0.003	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.003	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.003	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.003	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.003	0.997	0.000
Q96.0 Karyotype 45,X	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.000	0.997	0.003
H80-H83 Diseases of inner ear	0.000	0.997	0.003
Q52.5 Fusion of labia	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.997	0.003
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
R19.2 Visible peristalsis	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
R19.3 Abdominal rigidity	0.003	0.997	0.000
R19.1 Abnormal bowel sounds	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.997	0.000
Q54.1 Hypospadias, penile	0.002	0.997	0.000
M65 Synovitis and tenosynovitis	0.003	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.997	0.000
Q23.2 Congenital mitral stenosis	0.002	0.997	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.003	0.997	0.000
N83.2 Other and unspecified ovarian cysts	0.003	0.997	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.002	0.997	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.997	0.000
Q99.2 Fragile X chromosome	0.002	0.997	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.997	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.997	0.000
D25.2 Subserosal leiomyoma of uterus	0.003	0.997	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.997	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.997	0.000
Q55.3 Atresia of vas deferens	0.002	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.997	0.000
Q55.0 Absence and aplasia of testis	0.002	0.997	0.000
Q90.2 Trisomy 21, translocation	0.002	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.997	0.003
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.997	0.002
I49.5 Sick sinus syndrome	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.997	0.000
R19.6 Halitosis	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.998	0.000
Q91.6 Trisomy 13, translocation	0.002	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.998	0.000
Q91.2 Trisomy 18, translocation	0.002	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.998	0.000
Q92.7 Triploidy and polyploidy	0.002	0.998	0.000
Q92.6 Extra marker chromosomes	0.002	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.998	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.998	0.000
Q92.3 Minor partial trisomy	0.002	0.998	0.000
Q92.2 Major partial trisomy	0.002	0.998	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.002	0.998	0.000
Q93.9 Deletion from autosomes, unspecified	0.002	0.998	0.000
Q93.8 Other deletions from the autosomes	0.002	0.998	0.000
Q93.7 Deletions with other complex rearrangements	0.002	0.998	0.000
Q93.6 Deletions seen only at prometaphase	0.002	0.998	0.000
Q93.5 Other deletions of part of a chromosome	0.002	0.998	0.000
Q93.4 Deletion of short arm of chromosome 5	0.002	0.998	0.000
Q93.3 Deletion of short arm of chromosome 4	0.002	0.998	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.002	0.998	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.002	0.998	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.002	0.998	0.000
Q95.8 Other balanced rearrangements and structural markers	0.002	0.998	0.000
Q95.5 Individuals with autosomal fragile site	0.002	0.998	0.000
Q95.4 Individuals with marker heterochromatin	0.002	0.998	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.1 Chromosome inversion in normal individual	0.002	0.998	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.002	0.998	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.002	0.998	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.002	0.998	0.000
Q97.3 Female with 46,XY karyotype	0.002	0.998	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.002	0.998	0.000
Q97.1 Female with more than three X chromosomes	0.002	0.998	0.000
Q97.0 Karyotype 47,XXX	0.002	0.998	0.000
H81 Disorders of vestibular function	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.998	0.002
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.998	0.002
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.998	0.002
S80 Superficial injury of lower leg	0.000	0.998	0.002
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
M65.3 Trigger finger	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.000	0.998	0.002
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.002	0.998	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.002	0.998	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.002	0.998	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.002	0.998	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.002	0.998	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.002	0.998	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.002
X41.9 Unspecified place	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
G00.8 Other bacterial meningitis	0.000	0.998	0.002
G00.3 Staphylococcal meningitis	0.000	0.998	0.002
G00.0 Haemophilus meningitis	0.000	0.998	0.002
N48.1 Balanoposthitis	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M65.1 Other infective (teno)synovitis	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G02.1 Meningitis in mycoses	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations