TreeWAS – Variant ID: rs1471403

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.127	0.873	0.000
M81.9 Osteoporosis, unspecified	0.117	0.883	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.100	0.900	0.000
H54.4 Blindness, one eye	0.100	0.900	0.000
H54 Blindness and low vision	0.100	0.900	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.099	0.901	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.099	0.901	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.099	0.901	0.000
M81 Osteoporosis without pathological fracture	0.098	0.902	0.000
H54.7 Unspecified visual loss	0.098	0.902	0.000
M80 Osteoporosis with pathological fracture	0.094	0.906	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.089	0.911	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.087	0.913	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.086	0.914	0.000
M80-M85 Disorders of bone density and structure	0.086	0.914	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.085	0.915	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.085	0.915	0.000
H54.9 Unspecified visual impairment (binocular)	0.084	0.916	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.082	0.917	0.000
H54.5 Low vision, one eye	0.081	0.919	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.081	0.919	0.000
H54.3 Unqualified visual loss, both eyes	0.079	0.921	0.000
M81.98 Osteoporosis, unspecified (Other)	0.078	0.922	0.000
H54.1 Blindness, one eye, low vision, other eye	0.078	0.922	0.000
M81.4 Drug-induced osteoporosis	0.076	0.924	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.076	0.924	0.000
M80.8 Other osteoporosis with pathological fracture	0.075	0.925	0.000
M81.8 Other osteoporosis	0.075	0.925	0.000
H54.0 Blindness, both eyes	0.073	0.927	0.000
H54.2 Low vision, both eyes	0.073	0.927	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.071	0.928	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.071	0.928	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.071	0.928	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.071	0.928	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.071	0.928	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.071	0.928	0.000
M81.1 Postoophorectomy osteoporosis	0.071	0.929	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.071	0.929	0.000
M81.6 Localised osteoporosis [Lequesne]	0.070	0.930	0.000
M81.5 Idiopathic osteoporosis	0.070	0.930	0.000
H54.6 Unqualified visual loss, one eye	0.070	0.930	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.069	0.931	0.000
M81.0 Postmenopausal osteoporosis	0.067	0.932	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.067	0.933	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.067	0.933	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.067	0.933	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.067	0.933	0.000
M83 Adult osteomalacia	0.067	0.933	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.066	0.934	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.065	0.935	0.000
H43.3 Other vitreous opacities	0.064	0.936	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.061	0.939	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.061	0.939	0.000
M81.89 Other osteoporosis (Site unspecified)	0.060	0.940	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.059	0.941	0.000
M81.2 Osteoporosis of disuse	0.058	0.942	0.000
M82 Osteoporosis in diseases classified elsewhere	0.057	0.943	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.057	0.943	0.000
M81.48 Drug-induced osteoporosis (Other)	0.055	0.945	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.055	0.945	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.055	0.945	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.055	0.945	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.055	0.945	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.055	0.945	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.055	0.945	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.055	0.945	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.055	0.945	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.055	0.945	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.055	0.945	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.055	0.945	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.055	0.945	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.055	0.945	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.055	0.945	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.055	0.945	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.055	0.945	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.054	0.946	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.054	0.946	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.054	0.946	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.054	0.946	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.054	0.946	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.054	0.946	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.054	0.946	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.054	0.946	0.000
M81.88 Other osteoporosis (Other)	0.054	0.946	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.054	0.946	0.000
M81.86 Other osteoporosis (Lower leg)	0.054	0.946	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.054	0.946	0.000
M81.84 Other osteoporosis (Hand)	0.054	0.946	0.000
M81.83 Other osteoporosis (Forearm)	0.054	0.946	0.000
M81.82 Other osteoporosis (Upper arm)	0.054	0.946	0.000
M81.81 Other osteoporosis (Shoulder region)	0.054	0.946	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.053	0.946	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.052	0.948	0.000
M81.80 Other osteoporosis (Multiple sites)	0.052	0.948	0.000
H43 Disorders of vitreous body	0.052	0.948	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.051	0.949	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.051	0.949	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.051	0.949	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.051	0.949	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.051	0.949	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.051	0.949	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.051	0.949	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.051	0.949	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.051	0.949	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.051	0.949	0.000
M83.3 Adult osteomalacia due to malnutrition	0.051	0.949	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.050	0.949	0.000
M81.58 Idiopathic osteoporosis (Other)	0.050	0.949	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.050	0.949	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.050	0.949	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.050	0.949	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.050	0.949	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.050	0.949	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.050	0.949	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.050	0.949	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.050	0.949	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.050	0.949	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.050	0.949	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.050	0.949	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.050	0.949	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.050	0.949	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.050	0.949	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.050	0.949	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.050	0.949	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.050	0.949	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.050	0.949	0.000
M83.9 Adult osteomalacia, unspecified	0.050	0.949	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.048	0.951	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.048	0.951	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.048	0.951	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.048	0.951	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.048	0.951	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.048	0.951	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.048	0.951	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.048	0.951	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.048	0.951	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.048	0.951	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.048	0.951	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.048	0.951	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.048	0.951	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.048	0.951	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.048	0.951	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.048	0.951	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.048	0.951	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.048	0.951	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.048	0.951	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.048	0.951	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.048	0.951	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.048	0.951	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.048	0.951	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.048	0.951	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.048	0.951	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.048	0.951	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.048	0.951	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.048	0.951	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.048	0.951	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.048	0.951	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.048	0.951	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.048	0.951	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.048	0.951	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.048	0.951	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.048	0.951	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.048	0.951	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.048	0.951	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.048	0.951	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.048	0.951	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.048	0.951	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.048	0.951	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.048	0.951	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.048	0.951	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.048	0.951	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.048	0.951	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.048	0.951	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.048	0.951	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.048	0.951	0.000
M83.1 Senile osteomalacia	0.048	0.952	0.000
M83.5 Other drug-induced osteomalacia in adults	0.048	0.952	0.000
M83.4 Aluminum bone disease	0.048	0.952	0.000
M83.2 Adult osteomalacia due to malabsorption	0.048	0.952	0.000
M83.0 Puerperal osteomalacia	0.048	0.952	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.047	0.952	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.047	0.952	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.047	0.952	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.047	0.952	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.047	0.952	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.047	0.952	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.047	0.952	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.047	0.952	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.047	0.952	0.000
M83.8 Other adult osteomalacia	0.047	0.953	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.044	0.956	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.044	0.956	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.044	0.956	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.044	0.956	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.044	0.956	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.044	0.956	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.044	0.956	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.044	0.956	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.044	0.956	0.000
H43.8 Other disorders of vitreous body	0.044	0.956	0.000
H43.9 Disorder of vitreous body, unspecified	0.044	0.956	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.043	0.956	0.000
M85 Other disorders of bone density and structure	0.042	0.957	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.042	0.958	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.042	0.958	0.000
M81.28 Osteoporosis of disuse (Other)	0.042	0.958	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.042	0.958	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.042	0.958	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.042	0.958	0.000
M81.24 Osteoporosis of disuse (Hand)	0.042	0.958	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.042	0.958	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.042	0.958	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.042	0.958	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.041	0.959	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.041	0.959	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.041	0.959	0.000
H43.2 Crystalline deposits in vitreous body	0.040	0.960	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.040	0.960	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.040	0.960	0.000
H43.0 Vitreous prolapse	0.039	0.961	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.039	0.961	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.038	0.962	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.038	0.962	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.038	0.962	0.000
M85.0 Fibrous dysplasia (monostotic)	0.037	0.963	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.037	0.963	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.037	0.963	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.037	0.963	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.037	0.963	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.037	0.963	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.037	0.963	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.037	0.963	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.037	0.963	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.037	0.963	0.000
M82.1 Osteoporosis in endocrine disorders	0.036	0.963	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.036	0.963	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.036	0.963	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.036	0.963	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.036	0.963	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.036	0.963	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.036	0.963	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.036	0.963	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.036	0.963	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.036	0.963	0.000
M83.12 Senile osteomalacia (Upper arm)	0.035	0.965	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.035	0.965	0.000
M83.18 Senile osteomalacia (Other)	0.035	0.965	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.035	0.965	0.000
M83.16 Senile osteomalacia (Lower leg)	0.035	0.965	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.035	0.965	0.000
M83.14 Senile osteomalacia (Hand)	0.035	0.965	0.000
M83.13 Senile osteomalacia (Forearm)	0.035	0.965	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.035	0.965	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.035	0.965	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.034	0.965	0.000
M83.08 Puerperal osteomalacia (Other)	0.034	0.965	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.034	0.965	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.034	0.965	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.034	0.965	0.000
M83.04 Puerperal osteomalacia (Hand)	0.034	0.965	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.034	0.965	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.034	0.965	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.034	0.965	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.034	0.965	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.034	0.965	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.034	0.965	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.034	0.965	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.034	0.965	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.034	0.965	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.034	0.965	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.034	0.965	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.034	0.965	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.034	0.965	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.034	0.965	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.034	0.965	0.000
M83.48 Aluminium bone disease (Other)	0.034	0.965	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.034	0.965	0.000
M83.46 Aluminium bone disease (Lower leg)	0.034	0.965	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.034	0.965	0.000
M83.44 Aluminium bone disease (Hand)	0.034	0.965	0.000
M83.43 Aluminium bone disease (Forearm)	0.034	0.965	0.000
M83.42 Aluminium bone disease (Upper arm)	0.034	0.965	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.034	0.965	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.034	0.965	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.034	0.965	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.034	0.965	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.034	0.965	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.034	0.965	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.034	0.965	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.034	0.965	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.034	0.965	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.034	0.965	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.034	0.965	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.034	0.965	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.034	0.966	0.000
M83.88 Other adult osteomalacia (Other)	0.034	0.966	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.034	0.966	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.034	0.966	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.034	0.966	0.000
M83.84 Other adult osteomalacia (Hand)	0.034	0.966	0.000
M83.83 Other adult osteomalacia (Forearm)	0.034	0.966	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.034	0.966	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.034	0.966	0.000
T39.0 Salicylates	0.033	0.967	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.033	0.967	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.033	0.967	0.000
M85.5 Aneurysmal bone cyst	0.031	0.969	0.000
M85.3 Osteitis condensans	0.031	0.969	0.000
M85.1 Skeletal fluorosis	0.031	0.969	0.000
M85.4 Solitary bone cyst	0.030	0.970	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.030	0.970	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.030	0.970	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.030	0.970	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.030	0.970	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.030	0.970	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.030	0.970	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.030	0.970	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.030	0.970	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.030	0.970	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.030	0.970	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.030	0.970	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.030	0.970	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.030	0.970	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.030	0.970	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.030	0.970	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.030	0.970	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.030	0.970	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.030	0.970	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.030	0.970	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.030	0.970	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.029	0.970	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.029	0.971	0.000
M85.2 Hyperostosis of skull	0.029	0.971	0.000
H43.1 Vitreous haemorrhage	0.028	0.972	0.000
M85.6 Other cyst of bone	0.028	0.972	0.000
T39.4 Antirheumatics, not elsewhere classified	0.027	0.972	0.000
T39.2 Pyrazolone derivatives	0.027	0.972	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.027	0.973	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.027	0.973	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.027	0.973	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.027	0.973	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.027	0.973	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.027	0.973	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.027	0.973	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.027	0.973	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.027	0.973	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.027	0.973	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.026	0.973	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.026	0.973	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.026	0.973	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.026	0.973	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.026	0.973	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.026	0.973	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.026	0.973	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.026	0.973	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.025	0.975	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.024	0.976	0.000
M85.9 Disorder of bone density and structure, unspecified	0.024	0.976	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.024	0.976	0.000
H53-H54 Visual disturbances and blindness	0.024	0.976	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.024	0.976	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.023	0.977	0.000
M85.68 Other cyst of bone (Other)	0.023	0.977	0.000
H43-H45 Disorders of vitreous body and globe	0.023	0.977	0.000
M85.66 Other cyst of bone (Lower leg)	0.022	0.978	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.022	0.978	0.000
M85.18 Skeletal fluorosis (Other)	0.022	0.978	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.022	0.978	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.022	0.978	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.022	0.978	0.000
M85.14 Skeletal fluorosis (Hand)	0.022	0.978	0.000
M85.13 Skeletal fluorosis (Forearm)	0.022	0.978	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.022	0.978	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.022	0.978	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.022	0.978	0.000
M85.39 Osteitis condensans (Site unspecified)	0.022	0.978	0.000
M85.38 Osteitis condensans (Other)	0.022	0.978	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.022	0.978	0.000
M85.36 Osteitis condensans (Lower leg)	0.022	0.978	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.022	0.978	0.000
M85.34 Osteitis condensans (Hand)	0.022	0.978	0.000
M85.33 Osteitis condensans (Forearm)	0.022	0.978	0.000
M85.32 Osteitis condensans (Upper arm)	0.022	0.978	0.000
M85.31 Osteitis condensans (Shoulder region)	0.022	0.978	0.000
M85.30 Osteitis condensans (Multiple sites)	0.022	0.978	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.022	0.978	0.000
M85.58 Aneurysmal bone cyst (Other)	0.022	0.978	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.022	0.978	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.022	0.978	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.022	0.978	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.022	0.978	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.022	0.978	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.022	0.978	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.022	0.978	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.022	0.978	0.000
M85.46 Solitary bone cyst (Lower leg)	0.022	0.978	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.021	0.978	0.000
M85.48 Solitary bone cyst (Other)	0.021	0.978	0.000
M85.44 Solitary bone cyst (Hand)	0.021	0.978	0.000
M85.43 Solitary bone cyst (Forearm)	0.021	0.978	0.000
M85.42 Solitary bone cyst (Upper arm)	0.021	0.978	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.021	0.978	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.021	0.978	0.000
M85.20 Hyperostosis of skull-Mult sites	0.021	0.978	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.021	0.978	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.021	0.978	0.000
M85.29 Hyperostosis of skull-Site unspec	0.021	0.979	0.000
M85.28 Hyperostosis of skull-Other	0.021	0.979	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.021	0.979	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.021	0.979	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.021	0.979	0.000
M85.24 Hyperostosis of skull-Hand	0.021	0.979	0.000
M85.23 Hyperostosis of skull-Forearm	0.021	0.979	0.000
M85.21 Hyperostosis of skull-Shldr region	0.021	0.979	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.021	0.979	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.021	0.979	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.021	0.979	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.020	0.980	0.000
M84 Disorders of continuity of bone	0.020	0.980	0.000
M85.64 Other cyst of bone (Hand)	0.020	0.980	0.000
M85.69 Other cyst of bone (Site unspecified)	0.020	0.980	0.000
M85.63 Other cyst of bone (Forearm)	0.020	0.980	0.000
M85.62 Other cyst of bone (Upper arm)	0.020	0.980	0.000
M85.61 Other cyst of bone (Shoulder region)	0.020	0.980	0.000
M85.60 Other cyst of bone (Multiple sites)	0.020	0.980	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.020	0.980	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.019	0.981	0.000
T47.6 Antidiarrhoeal drugs	0.019	0.981	0.000
T47.0 Histamine H(2)-receptor antagonists	0.019	0.981	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.019	0.981	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.019	0.981	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.019	0.981	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.018	0.981	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.018	0.981	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.018	0.981	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.018	0.981	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.018	0.981	0.000
T44.0 Anticholinesterase agents	0.018	0.981	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.018	0.982	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.018	0.982	0.000
M85.22 Hyperostosis of skull-Upper arm	0.018	0.982	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.017	0.982	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.017	0.982	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.017	0.982	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.017	0.982	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.017	0.982	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.017	0.982	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.017	0.982	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.017	0.982	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.017	0.982	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.017	0.982	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.982	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.017	0.983	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.017	0.983	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.017	0.983	0.000
T47.7 Emetics	0.017	0.983	0.000
T47.5 Digestants	0.017	0.983	0.000
T47.3 Saline and osmotic laxatives	0.017	0.983	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.017	0.983	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.017	0.983	0.000
O63.9 Long labour, unspecified	0.017	0.983	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.017	0.983	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.017	0.983	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.017	0.983	0.000
T50.4 Drugs affecting uric acid metabolism	0.017	0.983	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.017	0.983	0.000
T46.7 Peripheral vasodilators	0.017	0.983	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.016	0.983	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.016	0.984	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.016	0.984	0.000
T47.4 Other laxatives	0.016	0.984	0.000
T47.2 Stimulant laxatives	0.016	0.984	0.000
L03.0 Cellulitis of finger and toe	0.000	0.984	0.016
T41.2 Other and unspecified general anaesthetics	0.016	0.984	0.000
M85.8 Other specified disorders of bone density and structure	0.016	0.984	0.000
T36 Poisoning by systemic antibiotics	0.016	0.984	0.000
T50.8 Diagnostic agents	0.015	0.985	0.000
T46.1 Calcium-channel blockers	0.015	0.985	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.015	0.985	0.000
T50.1 Loop [high-ceiling] diuretics	0.015	0.985	0.000
T41.5 Therapeutic gases	0.015	0.985	0.000
T41.4 Anaesthetic, unspecified	0.015	0.985	0.000
T41.3 Local anaesthetics	0.015	0.985	0.000
T41.1 Intravenous anaesthetics	0.015	0.985	0.000
T41.0 Inhaled anaesthetics	0.015	0.985	0.000
M84.9 Disorder of continuity of bone, unspecified	0.015	0.985	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.015	0.985	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.015	0.985	0.000
T50.7 Analeptics and opioid receptor antagonists	0.015	0.985	0.000
T50.5 Appetite depressants	0.015	0.985	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.015	0.985	0.000
T50.0 Mineralocorticoids and their antagonists	0.015	0.985	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.015	0.985	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.014	0.985	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.985	0.000
H04.1 Other disorders of lachrymal gland	0.014	0.986	0.000
M84.3 Stress fracture, not elsewhere classified	0.014	0.986	0.000
T45.5 Anticoagulants	0.014	0.986	0.000
H44 Disorders of globe	0.014	0.986	0.000
M84.8 Other disorders of continuity of bone	0.014	0.986	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations