TreeWAS – Variant ID: rs150267141

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.4 Descending colon	0.341	0.659	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.333	0.667	0.000
D12.6 Colon, unspecified	0.327	0.673	0.000
D12.5 Sigmoid colon	0.318	0.682	0.000
D12.0 Caecum	0.295	0.705	0.000
D12.1 Appendix	0.247	0.753	0.000
D12.8 Rectum	0.240	0.760	0.000
D12.2 Ascending colon	0.237	0.763	0.000
D12.9 Anus and anal canal	0.191	0.809	0.000
D12.3 Transverse colon	0.186	0.814	0.000
D12.7 Rectosigmoid junction	0.165	0.835	0.000
I10 Essential (primary) hypertension	0.051	0.949	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.032	0.968	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.031	0.969	0.000
C67.9 Bladder, unspecified	0.000	0.970	0.030
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.030	0.970	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.028	0.972	0.000
O60-O75 Complications of labour and delivery	0.027	0.973	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.026	0.974	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.026	0.974	0.000
C67 Malignant neoplasm of bladder	0.000	0.974	0.026
O62 Abnormalities of forces of labour	0.025	0.975	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.023	0.977	0.000
C67.2 Lateral wall of bladder	0.000	0.977	0.023
O72 Postpartum haemorrhage	0.023	0.977	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.022	0.977	0.000
C67.6 Ureteric orifice	0.000	0.978	0.022
O75.0 Maternal distress during labour and delivery	0.022	0.978	0.000
O62.2 Other uterine inertia	0.022	0.978	0.000
C67.4 Posterior wall of bladder	0.000	0.978	0.021
I10-I15 Hypertensive diseases	0.021	0.979	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.021	0.979	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.021	0.979	0.000
O73 Retained placenta and membranes, without haemorrhage	0.021	0.979	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.021	0.979	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.021	0.979	0.000
O71 Other obstetric trauma	0.020	0.980	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.020	0.980	0.000
O66 Other obstructed labour	0.020	0.980	0.000
O74 Complications of anaesthesia during labour and delivery	0.020	0.980	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.020	0.980	0.000
O60 Preterm delivery	0.020	0.980	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.020	0.980	0.000
O62.0 Primary inadequate contractions	0.019	0.980	0.000
O75.9 Complication of labour and delivery, unspecified	0.019	0.981	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.019	0.981	0.000
O75.4 Other complications of obstetric surgery and procedures	0.019	0.981	0.000
O75.3 Other infection during labour	0.019	0.981	0.000
O75.1 Shock during or following labour and delivery	0.019	0.981	0.000
C67.8 Overlapping lesion of bladder	0.000	0.981	0.019
C67.7 Urachus	0.000	0.981	0.019
C67.5 Bladder neck	0.000	0.981	0.019
C67.3 Anterior wall of bladder	0.000	0.981	0.019
C67.1 Dome of bladder	0.000	0.981	0.019
C67.0 Trigone of bladder	0.000	0.981	0.019
O75.8 Other specified complications of labour and delivery	0.019	0.981	0.000
I11 Hypertensive heart disease	0.019	0.981	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.018	0.982	0.000
O62.9 Abnormality of forces of labour, unspecified	0.018	0.982	0.000
O62.8 Other abnormalities of forces of labour	0.018	0.982	0.000
O62.1 Secondary uterine inertia	0.018	0.982	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.018	0.982	0.000
O69.8 Labour and delivery complicated by other cord complications	0.018	0.982	0.000
O62.3 Precipitate labour	0.017	0.982	0.000
O72.1 Other immediate postpartum haemorrhage	0.018	0.982	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.017	0.983	0.000
O63 Long labour	0.017	0.983	0.000
Z42 Follow-up care involving plastic surgery	0.017	0.983	0.000
O61 Failed induction of labour	0.017	0.983	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.017	0.983	0.000
O73.0 Retained placenta, without haemorrhage	0.017	0.983	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.017	0.983	0.000
O72.0 Third-stage haemorrhage	0.017	0.983	0.000
O72.3 Postpartum coagulation defects	0.016	0.983	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.016	0.984	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.016	0.984	0.000
D10-D36 Benign neoplasms	0.016	0.984	0.000
I15 Secondary hypertension	0.016	0.984	0.000
I13 Hypertensive heart and renal disease	0.016	0.984	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.015	0.984	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.015	0.985	0.000
O64.5 Obstructed labour due to compound presentation	0.015	0.985	0.000
O64.4 Obstructed labour due to shoulder presentation	0.015	0.985	0.000
O64.3 Obstructed labour due to brow presentation	0.015	0.985	0.000
O64.2 Obstructed labour due to face presentation	0.015	0.985	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.015	0.985	0.000
O71.4 Obstetric high vaginal laceration alone	0.015	0.985	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.015	0.985	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.015	0.985	0.000
O69.3 Labour and delivery complicated by short cord	0.015	0.985	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.015	0.985	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.015	0.985	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.015	0.985	0.000
O71.9 Obstetric trauma, unspecified	0.015	0.985	0.000
O71.8 Other specified obstetric trauma	0.015	0.985	0.000
O71.7 Obstetric haematoma of pelvis	0.015	0.985	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.015	0.985	0.000
O71.5 Other obstetric injury to pelvic organs	0.015	0.985	0.000
O71.3 Obstetric laceration of cervix	0.015	0.985	0.000
O71.2 Postpartum inversion of uterus	0.015	0.985	0.000
O71.1 Rupture of uterus during labour	0.015	0.985	0.000
O71.0 Rupture of uterus before onset of labour	0.015	0.985	0.000
Y52 Agents primarily affecting the cardiovascular system	0.015	0.985	0.000
O66.9 Obstructed labour, unspecified	0.014	0.985	0.000
O66.8 Other specified obstructed labour	0.014	0.985	0.000
O66.4 Failed trial of labour, unspecified	0.014	0.985	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.014	0.985	0.000
O66.2 Obstructed labour due to unusually large foetus	0.014	0.985	0.000
O66.1 Obstructed labour due to locked twins	0.014	0.985	0.000
O60.3 Preterm delivery without spontaneous labour	0.014	0.985	0.000
O60.2 Preterm spontaneous labour with term delivery	0.014	0.985	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.014	0.985	0.000
O60.0 Preterm labour without delivery	0.014	0.985	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.014	0.985	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.014	0.985	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.014	0.985	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.014	0.985	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.014	0.985	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.014	0.985	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.014	0.985	0.000
O65.0 Obstructed labour due to deformed pelvis	0.014	0.985	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.014	0.985	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.014	0.985	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.014	0.985	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.014	0.985	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.014	0.985	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.014	0.985	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.014	0.985	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.014	0.985	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.014	0.985	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.014	0.985	0.000
Y43.3 Other antineoplastic drugs	0.014	0.986	0.000
O70 Perineal laceration during delivery	0.012	0.986	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.014	0.986	0.000
D17 Benign lipomatous neoplasm	0.014	0.986	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.014	0.986	0.000
Y43 Primarily systemic agents	0.014	0.986	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.014	0.986	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.014	0.986	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.013	0.986	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.013	0.986	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.986	0.013
D26 Other benign neoplasms of uterus	0.013	0.987	0.000
D30 Benign neoplasm of urinary organs	0.013	0.987	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.013	0.987	0.000
O63.9 Long labour, unspecified	0.013	0.987	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.013	0.987	0.000
O67.8 Other intrapartum haemorrhage	0.013	0.987	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.013	0.987	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.987	0.013
O64.1 Obstructed labour due to breech presentation	0.013	0.987	0.000
H72 Perforation of tympanic membrane	0.000	0.987	0.013
H71 Cholesteatoma of middle ear	0.000	0.987	0.013
O70.0 First degree perineal laceration during delivery	0.000	0.987	0.013
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.013	0.987	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.013	0.987	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.013	0.987	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.013	0.987	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.013	0.987	0.000
Y40 Systemic antibiotics	0.013	0.987	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.013	0.987	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.013	0.987	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.013	0.987	0.000
D32 Benign neoplasm of meninges	0.013	0.987	0.000
D10 Benign neoplasm of mouth and pharynx	0.013	0.987	0.000
O61.9 Failed induction of labour, unspecified	0.012	0.987	0.000
O61.8 Other failed induction of labour	0.012	0.987	0.000
O61.1 Failed instrumental induction of labour	0.012	0.987	0.000
Y48 Anaesthetics and therapeutic gases	0.013	0.987	0.000
O63.0 Prolonged first stage (of labour)	0.012	0.988	0.000
O70.2 Third degree perineal laceration during delivery	0.012	0.988	0.001
D35.2 Pituitary gland	0.012	0.988	0.000
D31 Benign neoplasm of eye and adnexa	0.012	0.988	0.000
H73 Other disorders of tympanic membrane	0.000	0.988	0.012
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.012	0.988	0.000
H66 Suppurative and unspecified otitis media	0.000	0.988	0.012
D30.3 Bladder	0.012	0.988	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.012	0.988	0.000
D19 Benign neoplasm of mesothelial tissue	0.012	0.988	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.012	0.988	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.012	0.988	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.988	0.011
I13.9 Hypertensive heart and renal disease, unspecified	0.011	0.988	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.011	0.988	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.011	0.988	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.011	0.988	0.000
I15.9 Seconday hypertension, unspecified	0.011	0.988	0.000
I15.8 Other secondary hypertension	0.011	0.988	0.000
I15.2 Hypertension secondary to endocrine disorders	0.011	0.988	0.000
I15.1 Hypertension secondary to other renal disorders	0.011	0.988	0.000
I15.0 Renovascular hypertension	0.011	0.988	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.011	0.989	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.011	0.989	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.011	0.989	0.000
D16 Benign neoplasm of bone and articular cartilage	0.011	0.989	0.000
Y48.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
D26.0 Cervix uteri	0.011	0.989	0.000
Y52.1 Calcium-channel blockers	0.011	0.989	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.011	0.989	0.000
D35.1 Parathyroid gland	0.011	0.989	0.000
Y40.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
Y44 Agents primarily affecting blood constituents	0.011	0.989	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.011	0.989	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.011	0.989	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989	0.000
D36 Benign neoplasm of other and unspecified sites	0.011	0.989	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.011	0.989	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.011	0.989	0.000
Y52.7 Peripheral vasodilators	0.011	0.989	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.011	0.989	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.011	0.989	0.000
D26.9 Uterus, unspecified	0.011	0.989	0.000
Y57 Other and unspecified drugs and medicaments	0.011	0.989	0.000
D29 Benign neoplasm of male genital organs	0.011	0.989	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.011	0.989	0.000
O70.3 Fourth degree perineal laceration during delivery	0.009	0.989	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.010	0.989	0.000
H66.9 Otitis media, unspecified	0.000	0.989	0.011
Y40.8 Other systemic antibiotics	0.010	0.989	0.000
D11 Benign neoplasm of major salivary glands	0.010	0.989	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.010	0.989	0.000
Y59 Other and unspecified vaccines and biological substances	0.010	0.989	0.000
Y58 Bacterial vaccines	0.010	0.989	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.989	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.010	0.989	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.010	0.989	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.010	0.989	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.010	0.989	0.000
D33.3 Cranial nerves	0.010	0.989	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.010	0.989	0.000
D34 Benign neoplasm of thyroid gland	0.010	0.989	0.000
Y43.1 Antineoplastic antimetabolites	0.010	0.990	0.000
O70.9 Perineal laceration during delivery, unspecified	0.009	0.990	0.002
D28.2 Uterine tubes and ligaments	0.010	0.990	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.010	0.990	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.010	0.990	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.990	0.010
D10.1 Tongue	0.010	0.990	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.990	0.010
Y43.9 Primarily systemic agent, unspecified	0.010	0.990	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.010	0.990	0.000
Y43.6 Enzymes, not elsewhere classified	0.010	0.990	0.000
Y43.5 Acidifying and alkalising agents	0.010	0.990	0.000
Y43.2 Antineoplastic natural products	0.010	0.990	0.000
Y43.0 Antiallergic and antiemetic drugs	0.010	0.990	0.000
D23 Other benign neoplasms of skin	0.010	0.990	0.000
D35.9 Endocrine gland, unspecified	0.010	0.990	0.000
D35.8 Pluriglandular involvement	0.010	0.990	0.000
D35.7 Other specified endocrine glands	0.010	0.990	0.000
D35.6 Aortic body and other paraganglia	0.010	0.990	0.000
D35.5 Carotid body	0.010	0.990	0.000
D35.4 Pineal gland	0.010	0.990	0.000
D35.3 Craniopharyngeal duct	0.010	0.990	0.000
H69 Other disorders of Eustachian tube	0.000	0.990	0.010
D32.9 Meninges, unspecified	0.010	0.990	0.000
O61.0 Failed medical induction of labour	0.010	0.990	0.000
D26.1 Corpus uteri	0.010	0.990	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.010	0.990	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.010	0.990	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.010	0.990	0.000
D26.7 Other parts of uterus	0.010	0.990	0.000
D30.9 Urinary organ, unspecified	0.010	0.990	0.000
D30.7 Other urinary organs	0.010	0.990	0.000
D30.4 Urethra	0.010	0.990	0.000
D30.2 Ureter	0.010	0.990	0.000
D30.1 Renal pelvis	0.010	0.990	0.000
D30.0 Kidney	0.010	0.990	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.010	0.990	0.000
Y48.3 Local anaesthetics	0.010	0.990	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.010	0.990	0.000
D23.3 Skin of other and unspecified parts of face	0.010	0.990	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.990	0.010
H70 Mastoiditis and related conditions	0.000	0.990	0.010
H68 Eustachian salpingitis and obstruction	0.000	0.990	0.010
H67 Otitis media in diseases classified elsewhere	0.000	0.990	0.010
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.010	0.990	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.990	0.010
H72.1 Attic perforation of tympanic membrane	0.000	0.990	0.010
D32.0 Cerebral meninges	0.010	0.990	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.010	0.990	0.000
D10.0 Lip	0.010	0.990	0.000
D31.3 Choroid	0.009	0.990	0.000
D13.3 Other and unspecified parts of small intestine	0.009	0.990	0.000
D28.0 Vulva	0.009	0.990	0.000
D35.0 Adrenal gland	0.009	0.990	0.000
D33.9 Central nervous system, unspecified	0.009	0.991	0.000
D33.7 Other specified parts of central nervous system	0.009	0.991	0.000
D33.4 Spinal cord	0.009	0.991	0.000
D33.2 Brain, unspecified	0.009	0.991	0.000
D33.1 Brain, infratentorial	0.009	0.991	0.000
D33.0 Brain, supratentorial	0.009	0.991	0.000
D28.9 Female genital organ, unspecified	0.009	0.991	0.000
D28.7 Other specified female genital organs	0.009	0.991	0.000
D28.1 Vagina	0.009	0.991	0.000
O63.1 Prolonged second stage (of labour)	0.009	0.991	0.000
Y40.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
Y40.6 Rifamycins	0.009	0.991	0.000
Y40.5 Aminoglycosides	0.009	0.991	0.000
Y40.4 Tetracyclines	0.009	0.991	0.000
Y40.3 Macrolides	0.009	0.991	0.000
Y40.2 Chloramphenicol group	0.009	0.991	0.000
D32.1 Spinal meninges	0.009	0.991	0.000
D10.9 Pharynx, unspecified	0.009	0.991	0.000
D10.7 Hypopharynx	0.009	0.991	0.000
D10.6 Nasopharynx	0.009	0.991	0.000
D10.5 Other parts of oropharynx	0.009	0.991	0.000
D10.4 Tonsil	0.009	0.991	0.000
D10.2 Floor of mouth	0.009	0.991	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.009	0.991	0.000
Y48.5 Therapeutic gases	0.009	0.991	0.000
Y48.4 Anaesthetic, unspecified	0.009	0.991	0.000
Y48.1 Parenteral anaesthetics	0.009	0.991	0.000
Y48.0 Inhaled anaesthetics	0.009	0.991	0.000
D23.2 Skin of ear and external auricular canal	0.009	0.991	0.000
D31.9 Eye, unspecified	0.009	0.991	0.000
D31.6 Orbit, unspecified	0.009	0.991	0.000
D31.5 Lachrymal gland and duct	0.009	0.991	0.000
D31.4 Ciliary body	0.009	0.991	0.000
D31.2 Retina	0.009	0.991	0.000
D31.1 Cornea	0.009	0.991	0.000
D31.0 Conjunctiva	0.009	0.991	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.991	0.009
H73.1 Chronic myringitis	0.000	0.991	0.009
H73.0 Acute myringitis	0.000	0.991	0.009
I12 Hypertensive renal disease	0.009	0.991	0.000
D13.0 Oesophagus	0.009	0.991	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.991	0.009
D10.3 Other and unspecified parts of mouth	0.009	0.991	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.991	0.009
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.991	0.009
H66.0 Acute suppurative otitis media	0.000	0.991	0.009
D23.4 Skin of scalp and neck	0.009	0.991	0.000
Y54.3 Benzothiadiazine derivatives	0.009	0.991	0.000
Y44.2 Anticoagulants	0.009	0.991	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.009	0.991	0.000
D36.7 Other specified sites	0.009	0.991	0.000
D27 Benign neoplasm of ovary	0.009	0.991	0.000
Y43.4 Immunosuppressive agents	0.008	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.009	0.991	0.000
D15.9 Intrathoracic organ, unspecified	0.008	0.991	0.000
D15.7 Other specified intrathoracic organs	0.008	0.991	0.000
D15.2 Mediastinum	0.008	0.991	0.000
D15.1 Heart	0.008	0.991	0.000
D15.0 Thymus	0.008	0.991	0.000
D19.9 Mesothelial tissue, unspecified	0.008	0.991	0.000
D19.7 Mesothelial tissue of other sites	0.008	0.991	0.000
D19.1 Mesothelial tissue of peritoneum	0.008	0.991	0.000
D19.0 Mesothelial tissue of pleura	0.008	0.991	0.000
D20.1 Peritoneum	0.008	0.991	0.000
D20.0 Retroperitoneum	0.008	0.991	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.008	0.991	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.991	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.991	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.991	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.991	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.008	0.991	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.991	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.008	0.991	0.000
Y51.0 Anticholinesterase agents	0.008	0.991	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.991	0.008
D36.0 Lymph nodes	0.008	0.992	0.000
Y56.9 Topical agent, unspecified	0.008	0.992	0.000
Y56.8 Other topical agents	0.008	0.992	0.000
Y56.7 Dental drugs, topically applied	0.008	0.992	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.008	0.992	0.000
Y56.5 Ophthalmological drugs and preparations	0.008	0.992	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.992	0.000
Y56.3 Emollients, demulcents and protectants	0.008	0.992	0.000
Y56.2 Local astringents and local detergents	0.008	0.992	0.000
Y56.1 Antipruritics	0.008	0.992	0.000
Y57.5 X-ray contrast media	0.008	0.992	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.992	0.008
D13.9 Ill-defined sites within the digestive system	0.008	0.992	0.000
D13.7 Endocrine pancreas	0.008	0.992	0.000
D13.6 Pancreas	0.008	0.992	0.000
D13.5 Extrahepatic bile ducts	0.008	0.992	0.000
D13.4 Liver	0.008	0.992	0.000
D13.2 Duodenum	0.008	0.992	0.000
D16.9 Bone and articular cartilage, unspecified	0.008	0.992	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.008	0.992	0.000
D16.7 Ribs, sternum and clavicle	0.008	0.992	0.000
D16.6 Vertebral column	0.008	0.992	0.000
D16.5 Lower jaw bone	0.008	0.992	0.000
D16.2 Long bones of lower limb	0.008	0.992	0.000
D16.1 Short bones of upper limb	0.008	0.992	0.000
D16.0 Scapula and long bones of upper limb	0.008	0.992	0.000
D16.3 Short bones of lower limb	0.008	0.992	0.000
D18 Haemangioma and lymphangioma, any site	0.008	0.992	0.000
Y45.2 Propionic acid derivatives	0.008	0.992	0.000
Y54.9 Mineral salts, not elsewhere classified	0.008	0.992	0.000
Y54.8 Agents affecting uric acid metabolism	0.008	0.992	0.000
Y54.7 Agents affecting calcification	0.008	0.992	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
Y54.5 Other diuretics	0.008	0.992	0.000
Y54.4 Loop [high-ceiling] diuretics	0.008	0.992	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.008	0.992	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.008	0.992	0.000
Y54.0 Mineralocorticoids	0.008	0.992	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.008	0.992	0.000
Y44.7 Plasma substitutes	0.008	0.992	0.000
Y44.6 Natural blood and blood products	0.008	0.992	0.000
Y44.5 Thrombolytic drugs	0.008	0.992	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.008	0.992	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.008	0.992	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.008	0.992	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.008	0.992	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.992	0.008
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.992	0.000
Y45.5 4-Aminophenol derivatives	0.008	0.992	0.000
Y45.4 Antirheumatics	0.008	0.992	0.000
D36.9 Benign neoplasm of unspecified site	0.008	0.992	0.000
Y45.1 Salicylates	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.992	0.008
Y57.8 Other drugs and medicaments	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
D29.9 Male genital organ, unspecified	0.008	0.992	0.000
D29.7 Other male genital organs	0.008	0.992	0.000
D29.4 Scrotum	0.008	0.992	0.000
D29.3 Epididymis	0.008	0.992	0.000
D29.2 Testis	0.008	0.992	0.000
D29.0 Penis	0.008	0.992	0.000
Y49.2 Other and unspecified antidepressants	0.008	0.992	0.000
Y49.9 Psychotropic drug, unspecified	0.008	0.992	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y49.7 Psychostimulants with abuse potential	0.008	0.992	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.008	0.992	0.000
Y49.5 Other antipsychotics and neuroleptics	0.008	0.992	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.008	0.992	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.008	0.992	0.000
D11.9 Major salivary gland, unspecified	0.008	0.992	0.000
D11.7 Other major salivary glands	0.008	0.992	0.000
D16.4 Bones of skull and face	0.008	0.992	0.000
Y46.8 Antispasticity drugs	0.008	0.992	0.000
Y46.7 Anti-Parkinsonism drugs	0.008	0.992	0.000
Y46.6 Other and unspecified antiepileptics	0.008	0.992	0.000
Y46.5 Valproic acid	0.008	0.992	0.000
Y46.4 Iminostilbenes	0.008	0.992	0.000
Y46.3 Deoxybarbiturates	0.008	0.992	0.000
Y46.2 Hydantoin derivatives	0.008	0.992	0.000
Y46.1 Oxazolidinediones	0.008	0.992	0.000
Y46.0 Succinimides	0.008	0.992	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.008	0.992	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.008	0.992	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.008	0.992	0.000
Y47.4 Bromine compounds	0.008	0.992	0.000
Y47.3 Paraldehyde	0.008	0.992	0.000
Y47.2 Chloral derivatives	0.008	0.992	0.000
Y47.1 Benzodiazepines	0.008	0.992	0.000
Y47.0 Barbiturates, not elsewhere classified	0.008	0.992	0.000
Y50.9 Central nervous system stimulant, unspecified	0.008	0.992	0.000
Y50.8 Other central nervous system stimulants	0.008	0.992	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.008	0.992	0.000
Y50.1 Opioid receptor antagonists	0.008	0.992	0.000
Y50.0 Analeptics	0.008	0.992	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.008	0.992	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
Y53.7 Emetics	0.008	0.992	0.000
Y53.6 Antidiarrhoeal drugs	0.008	0.992	0.000
Y53.5 Digestants	0.008	0.992	0.000
Y53.4 Other laxatives	0.008	0.992	0.000
Y53.3 Saline and osmotic laxatives	0.008	0.992	0.000
Y53.2 Stimulant laxatives	0.008	0.992	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
Y53.0 Histamine H2-receptor antagonists	0.008	0.992	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.992	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
Y55.5 Anticommon cold drugs	0.008	0.992	0.000
Y55.4 Expectorants	0.008	0.992	0.000
Y55.3 Antitussives	0.008	0.992	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.008	0.992	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.992	0.000
Y55.0 Oxytocic drugs	0.008	0.992	0.000
Y58.9 Other and unspecified bacterial vaccines	0.008	0.992	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.008	0.992	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.008	0.992	0.000
Y58.5 Diphtheria vaccine	0.008	0.992	0.000
Y58.4 Tetanus vaccine	0.008	0.992	0.000
Y58.3 Plague vaccine	0.008	0.992	0.000
Y58.2 Cholera vaccine	0.008	0.992	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.008	0.992	0.000
Y58.0 BCG vaccine	0.008	0.992	0.000
Y59.9 Vaccine or biological substance, unspecified	0.008	0.992	0.000
Y59.8 Other specified vaccines and biological substances	0.008	0.992	0.000
Y59.3 Immunoglobulin	0.008	0.992	0.000
Y59.2 Protozoal vaccines	0.008	0.992	0.000
Y59.1 Rickettsial vaccines	0.008	0.992	0.000
Y59.0 Viral vaccines	0.008	0.992	0.000
D23.9 Skin, unspecified	0.008	0.992	0.000
K57 Diverticular disease of intestine	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.007	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations