TreeWAS – Variant ID: rs1503059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.017	0.983	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.988	0.012
R39.1 Other difficulties with micturition	0.000	0.990	0.010
R39 Other symptoms and signs involving the urinary system	0.000	0.990	0.010
D62 Acute posthaemorrhagic anaemia	0.000	0.990	0.010
D86 Sarcoidosis	0.009	0.991	0.000
D86.9 Sarcoidosis, unspecified	0.008	0.992	0.000
D86.8 Sarcoidosis of other and combined sites	0.008	0.992	0.000
D86.1 Sarcoidosis of lymph nodes	0.008	0.992	0.000
R39.2 Extrarenal uraemia	0.000	0.993	0.007
R39.0 Extravasation of urine	0.000	0.993	0.007
D80-D89 Certain disorders involving the immune mechanism	0.007	0.993	0.000
D86.0 Sarcoidosis of lung	0.006	0.993	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.006	0.994	0.000
D86.3 Sarcoidosis of skin	0.006	0.994	0.000
D80 Immunodeficiency with predominantly antibody defects	0.006	0.994	0.000
D83 Common variable immunodeficiency	0.006	0.994	0.000
D84 Other immunodeficiencies	0.006	0.994	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.006	0.994	0.000
D82 Immunodeficiency associated with other major defects	0.006	0.994	0.000
D83.9 Common variable immunodeficiency, unspecified	0.006	0.994	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.006	0.994	0.000
D84.1 Defects in the complement system	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
K65.0 Acute peritonitis	0.005	0.995	0.000
D82.1 Di George's syndrome	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.995	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.995	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.995	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.995	0.000
R47.0 Dysphasia and aphasia	0.000	0.995	0.005
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
D84.8 Other specified immunodeficiencies	0.004	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.995	0.000
K65.9 Peritonitis, unspecified	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.004	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.004	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.004	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.004	0.996	0.000
L29.9 Pruritus, unspecified	0.000	0.996	0.004
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.996	0.004
D81.9 Combined immunodeficiency, unspecified	0.004	0.996	0.000
D81.8 Other combined immunodeficiencies	0.004	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.004	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.004	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.004	0.996	0.000
D81.4 Nezelof's syndrome	0.004	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.004	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.004	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.004	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.004	0.996	0.000
L29.0 Pruritus ani	0.000	0.996	0.004
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.996	0.000
L29.2 Pruritus vulvae	0.000	0.996	0.004
L29 Pruritus	0.000	0.996	0.004
M25.57 Pain in joint (Ankle and foot)	0.000	0.996	0.004
K65 Peritonitis	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.996	0.004
O02.1 Missed abortion	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
E87.7 Fluid overload	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
K10.8 Other specified diseases of jaws	0.000	0.997	0.003
S52.00 Fracture of upper end of ulna (closed)	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.997	0.003
L29.1 Pruritus scroti	0.000	0.997	0.003
R47.1 Dysarthria and anarthria	0.000	0.997	0.003
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.000	0.997	0.003
O02 Other abnormal products of conception	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.997	0.000
S92.40 Fracture of great toe (closed)	0.002	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
L29.8 Other pruritus	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
R06.2 Wheezing	0.000	0.998	0.002
K31.8 Other specified diseases of stomach and duodenum	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.998	0.002
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.000	0.998	0.002
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
C50.4 Upper-outer quadrant of breast	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
G83.4 Cauda equina syndrome	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
D61 Other aplastic anaemias	0.000	0.998	0.002
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.000	0.998	0.002
D60.1 Transient acquired pure red cell aplasia	0.000	0.998	0.002
D60.0 Chronic acquired pure red cell aplasia	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
K65.8 Other peritonitis	0.001	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.002	0.998	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.002	0.998	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.002	0.998	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.000	0.998	0.002
D61.0 Constitutional aplastic anaemia	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.001	0.998	0.000
M85.68 Other cyst of bone (Other)	0.001	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.998	0.000
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
I46 Cardiac arrest	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
S91.0 Open wound of ankle	0.001	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.001	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
L60.0 Ingrowing nail	0.002	0.998	0.000
K10 Other diseases of jaws	0.000	0.998	0.002
S52.0 Fracture of upper end of ulna	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.998	0.000
F60.8 Other specific personality disorders	0.001	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.001	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.001	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.001	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.001	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.001	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.001	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.001	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.001	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.001	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.001	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.001	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.001	0.998	0.000
M85.38 Osteitis condensans (Other)	0.001	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.001	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.001	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.001	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.001	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.001	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.001	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.001	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.001	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.001	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.001	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.001	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.001	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.001	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.001	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.001	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.001	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.998	0.000
M62.6 Muscle strain	0.001	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
O00.9 Ectopic pregnancy, unspecified	0.001	0.998	0.000
W84.9 Unspecified place	0.001	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.001	0.998	0.000
S93.1 Dislocation of toe(s)	0.001	0.998	0.000
R49 Voice disturbances	0.000	0.998	0.001
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.001	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.001
K10.2 Inflammatory conditions of jaws	0.000	0.998	0.001
K10.0 Developmental disorders of jaws	0.000	0.998	0.001
G63 Polyneuropathy in diseases classified elsewhere	0.001	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
F60.0 Paranoid personality disorder	0.001	0.999	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.999	0.001
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
K01.1 Impacted teeth	0.001	0.999	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
M62 Other disorders of muscle	0.001	0.999	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.999	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.999	0.000
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
Z29 Need for other prophylactic measures	0.001	0.999	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
F60.5 Anankastic personality disorder	0.001	0.999	0.000
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
M81.4 Drug-induced osteoporosis	0.001	0.999	0.000
R49.8 Other and unspecified voice disturbances	0.000	0.999	0.001
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
K10.9 Disease of jaws, unspecified	0.000	0.999	0.001
K10.1 Giant cell granuloma, central	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
E83.3 Disorders of phosphorus metabolism	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.001	0.999	0.000
Z29.8 Other specified prophylactic measures	0.001	0.999	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.999	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.999	0.000
M62.64 Muscle strain (Hand)	0.001	0.999	0.000
M62.63 Muscle strain (Forearm)	0.001	0.999	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.999	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.999	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.999	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.999	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.999	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.999	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.999	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.999	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.999	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.999	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.999	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.999	0.000
R49.0 Dysphonia	0.000	0.999	0.001
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.999	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.999	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.001	0.999	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.001	0.999	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.001	0.999	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.001	0.999	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.001	0.999	0.000
G63.1 Polyneuropathy in neoplastic disease	0.001	0.999	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.000	0.999	0.001
R49.2 Hypernasality and hyponasality	0.000	0.999	0.001
R49.1 Aphonia	0.000	0.999	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
M62.4 Contracture of muscle	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.001	0.999	0.000
K10.3 Alveolitis of jaws	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.999	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.999	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.999	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.999	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.999	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.999	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.999	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.999	0.000
I69.3 Sequelae of cerebral infarction	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.001	0.999	0.000
Z29.9 Prophylactic measure, unspecified	0.001	0.999	0.000
L08 Other local infections of skin and subcutaneous tissue	0.000	0.999	0.001
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
E10.3 With ophthalmic complications	0.001	0.999	0.000
I95.0 Idiopathic hypotension	0.001	0.999	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.999	0.001
M82.1 Osteoporosis in endocrine disorders	0.001	0.999	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M65.8 Other synovitis and tenosynovitis	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.999	0.001
R48.2 Apraxia	0.000	0.999	0.001
R48.1 Agnosia	0.000	0.999	0.001
R48.0 Dyslexia and alexia	0.000	0.999	0.001
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations