TreeWAS – Variant ID: rs1514178

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.000	0.969	0.031
H40 Glaucoma	0.000	0.972	0.028
H40.2 Primary angle-closure glaucoma	0.000	0.974	0.026
H40.0 Glaucoma suspect	0.000	0.976	0.024
H40.1 Primary open-angle glaucoma	0.000	0.977	0.023
H40.8 Other glaucoma	0.000	0.980	0.020
H40.6 Glaucoma secondary to drugs	0.000	0.980	0.020
H40.4 Glaucoma secondary to eye inflammation	0.000	0.980	0.020
H40.3 Glaucoma secondary to eye trauma	0.000	0.980	0.020
H40.5 Glaucoma secondary to other eye disorders	0.000	0.980	0.020
H40-H42 Glaucoma	0.000	0.987	0.013
H42 Glaucoma in diseases classified elsewhere	0.000	0.990	0.009
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.993	0.007
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.993	0.007
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.993	0.007
L40.9 Psoriasis, unspecified	0.007	0.993	0.000
K29.6 Other gastritis	0.000	0.993	0.007
L40 Psoriasis	0.007	0.993	0.000
L03.3 Cellulitis of trunk	0.006	0.994	0.000
L40.5 Arthropathic psoriasis	0.006	0.994	0.000
L40.0 Psoriasis vulgaris	0.006	0.994	0.000
L03 Cellulitis	0.006	0.994	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.995	0.005
L03.0 Cellulitis of finger and toe	0.005	0.995	0.000
L03.8 Cellulitis of other sites	0.005	0.995	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.005	0.995	0.000
L40.8 Other psoriasis	0.005	0.995	0.000
L40.4 Guttate psoriasis	0.005	0.995	0.000
L40.3 Pustulosis palmaris et plantaris	0.005	0.995	0.000
L40.2 Acrodermatitis continua	0.005	0.995	0.000
L40.1 Generalised pustular psoriasis	0.005	0.995	0.000
H52.1 Myopia	0.000	0.995	0.005
L02 Cutaneous abscess, furuncle and carbuncle	0.005	0.995	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.005	0.995	0.000
L04 Acute lymphadenitis	0.004	0.995	0.000
L03.9 Cellulitis, unspecified	0.004	0.995	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
L40-L45 Papulosquamous disorders	0.004	0.996	0.000
L03.2 Cellulitis of face	0.004	0.996	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
L04.9 Acute lymphadenitis, unspecified	0.004	0.996	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.996	0.004
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.996	0.004
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
H52 Disorders of refraction and accommodation	0.000	0.996	0.004
L01 Impetigo	0.004	0.996	0.000
L00 Staphylococcal scalded skin syndrome	0.004	0.996	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.996	0.004
L05 Pilonidal cyst	0.004	0.996	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.004	0.996	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.004	0.996	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.004	0.996	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.004	0.996	0.000
L08 Other local infections of skin and subcutaneous tissue	0.004	0.996	0.000
G43.9 Migraine, unspecified	0.000	0.996	0.004
H52.0 Hypermetropia	0.000	0.996	0.004
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.996	0.004
B95-B98 Bacterial, viral and other infectious agents	0.000	0.996	0.004
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.996	0.004
Z50 Care involving use of rehabilitation procedures	0.000	0.996	0.004
L04.8 Acute lymphadenitis of other sites	0.003	0.996	0.000
L04.3 Acute lymphadenitis of lower limb	0.003	0.996	0.000
L04.2 Acute lymphadenitis of upper limb	0.003	0.996	0.000
L04.1 Acute lymphadenitis of trunk	0.003	0.996	0.000
L04.0 Acute lymphadenitis of face, head and neck	0.003	0.996	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.003	0.996	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.996	0.003
L08.8 Other specified local infections of skin and subcutaneous tissue	0.003	0.996	0.000
Z50.5 Speech therapy	0.000	0.996	0.003
E86 Volume depletion	0.000	0.997	0.003
L44 Other papulosquamous disorders	0.003	0.997	0.000
L41 Parapsoriasis	0.003	0.997	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.003	0.997	0.000
L42 Pityriasis rosea	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
H52.7 Disorder of refraction, unspecified	0.000	0.997	0.003
H52.6 Other disorders of refraction	0.000	0.997	0.003
H52.5 Disorders of accommodation	0.000	0.997	0.003
H52.4 Presbyopia	0.000	0.997	0.003
H52.3 Anisometropia and aniseikonia	0.000	0.997	0.003
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
L05.0 Pilonidal cyst with abscess	0.003	0.997	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.997	0.003
K92.1 Melaena	0.000	0.997	0.003
L01.1 Impetiginisation of other dermatoses	0.003	0.997	0.000
L01.0 Impetigo [any organism] [any site]	0.003	0.997	0.000
D64.9 Anaemia, unspecified	0.000	0.997	0.003
H52.2 Astigmatism	0.000	0.997	0.003
L08.1 Erythrasma	0.003	0.997	0.000
L08.0 Pyoderma	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
L50-L54 Urticaria and erythema	0.003	0.997	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
Z50.1 Other physical therapy	0.000	0.997	0.003
Z50.0 Cardiac rehabilitation	0.000	0.997	0.003
L05.9 Pilonidal cyst without abscess	0.003	0.997	0.000
Z50.6 Orthoptic training	0.000	0.997	0.003
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.997	0.003
Z50.3 Drug rehabilitation	0.000	0.997	0.003
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.997	0.003
L53 Other erythematous conditions	0.003	0.997	0.000
L50 Urticaria	0.003	0.997	0.000
L53.9 Erythematous condition, unspecified	0.003	0.997	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
L41.9 Parapsoriasis, unspecified	0.002	0.997	0.000
L41.8 Other parapsoriasis	0.002	0.997	0.000
L41.5 Retiform parapsoriasis	0.002	0.997	0.000
L41.4 Large plaque parapsoriasis	0.002	0.997	0.000
L41.3 Small plaque parapsoriasis	0.002	0.997	0.000
L41.2 Lymphomatoid papulosis	0.002	0.997	0.000
L41.1 Pityriasis lichenoides chronica	0.002	0.997	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.002	0.997	0.000
L44.9 Papulosquamous disorder, unspecified	0.002	0.997	0.000
L44.8 Other specified papulosquamous disorders	0.002	0.997	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.002	0.997	0.000
L44.3 Lichen ruber moniliformis	0.002	0.997	0.000
L44.2 Lichen striatus	0.002	0.997	0.000
L44.1 Lichen nitidus	0.002	0.997	0.000
L44.0 Pityriasis rubra pilaris	0.002	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
B37.0 Candidal stomatitis	0.000	0.997	0.003
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
L43.8 Other lichen planus	0.002	0.997	0.000
L43.3 Subacute (active) lichen planus	0.002	0.997	0.000
L43.2 Lichenoid drug reaction	0.002	0.997	0.000
L43.1 Bullous lichen planus	0.002	0.997	0.000
L43.0 Hypertrophic lichen planus	0.002	0.997	0.000
F32.9 Depressive episode, unspecified	0.000	0.997	0.003
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.997	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.997	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.997	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.997	0.002
Z50.2 Alcohol rehabilitation	0.000	0.997	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.002	0.997	0.000
L43.9 Lichen planus, unspecified	0.002	0.997	0.000
L50.0 Allergic urticaria	0.002	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y40 Systemic antibiotics	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
L54 Erythema in diseases classified elsewhere	0.002	0.998	0.000
L51 Erythema multiforme	0.002	0.998	0.000
L52 Erythema nodosum	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
L50.8 Other urticaria	0.002	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.002	0.998	0.000
L53.3 Other chronic figurate erythema	0.002	0.998	0.000
L53.2 Erythema marginatum	0.002	0.998	0.000
L53.1 Erythema annulare centrifugum	0.002	0.998	0.000
L53.0 Toxic erythema	0.002	0.998	0.000
L10-L14 Bullous disorders	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
H50 Other strabismus	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
H49 Paralytic strabismus	0.000	0.998	0.002
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
H26.4 After-cataract	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.998	0.002
B37 Candidiasis	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
K92 Other diseases of digestive system	0.000	0.998	0.002
Chapter VII Diseases of the eye and adnexa	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
F32 Depressive episode	0.000	0.998	0.002
G43 Migraine	0.000	0.998	0.002
L51.9 Erythema multiforme, unspecified	0.002	0.998	0.000
L51.8 Other erythema multiforme	0.002	0.998	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.002	0.998	0.000
L51.1 Bullous erythema multiforme	0.002	0.998	0.000
L51.0 Nonbullous erythema multiforme	0.002	0.998	0.000
L54.8 Erythema in other diseases classified elsewhere	0.002	0.998	0.000
L54.0 Erythema marginatum in acute rheumatic fever	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
H51.9 Disorder of binocular movement, unspecified	0.000	0.998	0.002
H51.8 Other specified disorders of binocular movement	0.000	0.998	0.002
H51.2 Internuclear ophthalmoplegia	0.000	0.998	0.002
H51.1 Convergence insufficiency and excess	0.000	0.998	0.002
H51.0 Palsy of conjugate gaze	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
Z92.3 Personal history of irradiation	0.000	0.998	0.002
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
L13 Other bullous disorders	0.002	0.998	0.000
L12 Pemphigoid	0.002	0.998	0.000
L11 Other acantholytic disorders	0.002	0.998	0.000
L10 Pemphigus	0.002	0.998	0.000
L14 Bullous disorders in diseases classified elsewhere	0.002	0.998	0.000
H50.8 Other specified strabismus	0.000	0.998	0.002
H50.6 Mechanical strabismus	0.000	0.998	0.002
H50.5 Heterophoria	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.000	0.998	0.002
H50.2 Vertical strabismus	0.000	0.998	0.002
K92.0 Haematemesis	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.998	0.002
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
H49.9 Paralytic strabismus, unspecified	0.000	0.998	0.002
H49.8 Other paralytic strabismus	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.998	0.002
H49.3 Total (external) ophthalmoplegia	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
B35-B49 Mycoses	0.000	0.998	0.002
Chapter XX External causes of morbidity and mortality	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.000	0.998	0.002
D64 Other anaemias	0.000	0.998	0.002
L20-L30 Dermatitis and eczema	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.000	0.998	0.002
W05.0 Home	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
W00-W19 Falls	0.002	0.998	0.000
B37.7 Candidal septicaemia	0.000	0.998	0.002
B37.6 Candidal endocarditis	0.000	0.998	0.002
B37.5 Candidal meningitis	0.000	0.998	0.002
B37.4 Candidiasis of other urogenital sites	0.000	0.998	0.002
B37.3 Candidiasis of vulva and vagina	0.000	0.998	0.002
B37.2 Candidiasis of skin and nail	0.000	0.998	0.002
B37.1 Pulmonary candidiasis	0.000	0.998	0.002
G43.1 Migraine with aura [classical migraine]	0.000	0.998	0.002
K92.8 Other specified diseases of digestive system	0.000	0.998	0.002
W05 Fall involving wheelchair	0.002	0.998	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.998	0.002
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
V10-V19 Pedal cyclist injured in transport accident	0.002	0.998	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
A04 Other bacterial intestinal infections	0.000	0.998	0.002
F32.8 Other depressive episodes	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.000	0.998	0.002
F32.0 Mild depressive episode	0.000	0.998	0.002
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
G43.8 Other migraine	0.000	0.998	0.002
G43.3 Complicated migraine	0.000	0.998	0.002
G43.2 Status migrainosus	0.000	0.998	0.002
G43.0 Migraine without aura [common migraine]	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.001
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
W13 Fall from, out of or through building or structure	0.002	0.998	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998	0.000
V40-V49 Car occupant injured in transport accident	0.002	0.998	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.998	0.002
W45.6 Industrial and construction area	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
X50-X57 Overexertion, travel and privation	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
W13.9 Unspecified place	0.002	0.998	0.000
W08 Fall involving other furniture	0.002	0.998	0.000
Chapter I Certain infectious and parasitic diseases	0.000	0.998	0.002
K92.9 Disease of digestive system, unspecified	0.000	0.998	0.002
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.001	0.998	0.000
W45 Foreign body or object entering through skin	0.001	0.998	0.000
W20-W49 Exposure to inanimate mechanical forces	0.001	0.998	0.000
V80-V89 Other land transport accidents	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.001
L10.9 Pemphigus, unspecified	0.001	0.998	0.000
L10.8 Other pemphigus	0.001	0.998	0.000
L10.5 Drug-induced pemphigus	0.001	0.998	0.000
L10.4 Pemphigus erythematosus	0.001	0.998	0.000
L10.3 Brazilian pemphigus [fogo selvagem]	0.001	0.998	0.000
L10.2 Pemphigus foliaceus	0.001	0.998	0.000
L10.1 Pemphigus vegetans	0.001	0.998	0.000
L10.0 Pemphigus vulgaris	0.001	0.998	0.000
L11.9 Acantholytic disorder, unspecified	0.001	0.998	0.000
L11.8 Other specified acantholytic disorders	0.001	0.998	0.000
L11.1 Transient acantholytic dermatosis [Grover]	0.001	0.998	0.000
L11.0 Acquired keratosis follicularis	0.001	0.998	0.000
L12.9 Pemphigoid, unspecified	0.001	0.998	0.000
L12.8 Other pemphigoid	0.001	0.998	0.000
L12.3 Acquired epidermolysis bullosa	0.001	0.998	0.000
L12.2 Chronic bullous disease of childhood	0.001	0.998	0.000
L12.1 Cicatricial pemphigoid	0.001	0.998	0.000
L12.0 Bullous pemphigoid	0.001	0.998	0.000
L13.9 Bullous disorder, unspecified	0.001	0.998	0.000
L13.8 Other specified bullous disorders	0.001	0.998	0.000
L13.1 Subcorneal pustular dermatitis	0.001	0.998	0.000
L13.0 Dermatitis herpetiformis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations