TreeWAS – Variant ID: rs1533087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M79.67 Pain in limb (Ankle and foot)	0.000	0.910	0.090
S42.20 Fracture of upper end of humerus (closed)	0.029	0.971	0.000
S42.2 Fracture of upper end of humerus	0.027	0.973	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.026	0.974	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.026	0.974	0.000
S42 Fracture of shoulder and upper arm	0.025	0.975	0.000
D80-D89 Certain disorders involving the immune mechanism	0.024	0.976	0.000
D86 Sarcoidosis	0.024	0.976	0.000
S42.1 Fracture of scapula	0.024	0.976	0.000
S42.10 Fracture of scapula (closed)	0.024	0.976	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.023	0.977	0.000
S42.4 Fracture of lower end of humerus	0.022	0.978	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.022	0.978	0.000
S42.3 Fracture of shaft of humerus	0.021	0.979	0.000
D86.3 Sarcoidosis of skin	0.020	0.980	0.000
S42.40 Fracture of lower end of humerus (closed)	0.020	0.980	0.000
D83 Common variable immunodeficiency	0.020	0.980	0.000
D86.1 Sarcoidosis of lymph nodes	0.020	0.980	0.000
D84 Other immunodeficiencies	0.020	0.980	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.020	0.980	0.000
S42.21 Fracture of upper end of humerus (open)	0.019	0.980	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.019	0.981	0.000
D86.0 Sarcoidosis of lung	0.019	0.981	0.000
D89.3 Immune reconstitution syndrome	0.019	0.981	0.000
S42.30 Fracture of shaft of humerus (closed)	0.019	0.981	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.019	0.981	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.019	0.981	0.000
D89.1 Cryoglobulinaemia	0.018	0.982	0.000
D86.9 Sarcoidosis, unspecified	0.018	0.982	0.000
D86.8 Sarcoidosis of other and combined sites	0.018	0.982	0.000
D81 Combined immunodeficiencies	0.018	0.982	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.018	0.982	0.000
S42.11 Fracture of scapula (open)	0.018	0.982	0.000
Z43.2 Attention to ileostomy	0.000	0.982	0.018
D82 Immunodeficiency associated with other major defects	0.017	0.983	0.000
D84.9 Immunodeficiency, unspecified	0.017	0.983	0.000
S42.41 Fracture of lower end of humerus (open)	0.017	0.983	0.000
D83.9 Common variable immunodeficiency, unspecified	0.016	0.984	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.016	0.984	0.000
D80 Immunodeficiency with predominantly antibody defects	0.016	0.984	0.000
D83.8 Other common variable immunodeficiencies	0.014	0.986	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.014	0.986	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.014	0.986	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.014	0.986	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.014	0.986	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.014	0.986	0.000
D84.8 Other specified immunodeficiencies	0.014	0.986	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.014	0.986	0.000
S42.31 Fracture of shaft of humerus (open)	0.013	0.986	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.013	0.986	0.000
D81.9 Combined immunodeficiency, unspecified	0.013	0.987	0.000
D81.8 Other combined immunodeficiencies	0.013	0.987	0.000
D81.7 Major histocompatibility complex class II deficiency	0.013	0.987	0.000
D81.6 Major histocompatibility complex class I deficiency	0.013	0.987	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.013	0.987	0.000
D81.4 Nezelof's syndrome	0.013	0.987	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.013	0.987	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.013	0.987	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.013	0.987	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.013	0.987	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.013	0.987	0.000
S42.0 Fracture of clavicle	0.013	0.987	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.987	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.987	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.987	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.012	0.987	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.987	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.987	0.000
D84.1 Defects in the complement system	0.012	0.987	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.012	0.988	0.000
D82.1 Di George's syndrome	0.012	0.988	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.012	0.988	0.000
H35.4 Peripheral retinal degeneration	0.012	0.988	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.011	0.988	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.011	0.989	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.011	0.989	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.011	0.989	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.011	0.989	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.011	0.989	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.011	0.989	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.011	0.989	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.011	0.989	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.011	0.989	0.000
D72 Other disorders of white blood cells	0.011	0.989	0.000
S42.01 Fracture of clavicle (open)	0.010	0.990	0.000
D70 Agranulocytosis	0.010	0.990	0.000
D55-D59 Haemolytic anaemias	0.010	0.990	0.000
D72.8 Other specified disorders of white blood cells	0.010	0.990	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.009	0.990	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.991	0.009
D72.1 Eosinophilia	0.009	0.991	0.000
D59 Acquired haemolytic anaemia	0.009	0.991	0.000
S40-S49 Injuries to the shoulder and upper arm	0.009	0.991	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.008	0.992	0.000
D76.3 Other histiocytosis syndromes	0.008	0.992	0.000
D57 Sickle-cell disorders	0.008	0.992	0.000
D74 Methaemoglobinaemia	0.008	0.992	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.008	0.992	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.008	0.992	0.000
D72.9 Disorder of white blood cells, unspecified	0.008	0.992	0.000
D72.0 Genetic anomalies of leukocytes	0.008	0.992	0.000
D59.1 Other autoimmune haemolytic anaemias	0.008	0.992	0.000
S41 Open wound of shoulder and upper arm	0.008	0.992	0.000
D55 Anaemia due to enzyme disorders	0.007	0.993	0.000
D58 Other hereditary haemolytic anaemias	0.007	0.993	0.000
D56 Thalassaemia	0.007	0.993	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.007	0.993	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.007	0.993	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.007	0.993	0.000
D57.1 Sickle-cell anaemia without crisis	0.007	0.993	0.000
D73 Diseases of spleen	0.007	0.993	0.000
T92.0 Sequelae of open wound of upper limb	0.007	0.993	0.000
D60-D64 Aplastic and other anaemias	0.007	0.993	0.000
D50-D53 Nutritional anaemias	0.007	0.993	0.000
S44 Injury of nerves at shoulder and upper arm level	0.007	0.993	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.006	0.993	0.000
S41.0 Open wound of shoulder	0.007	0.993	0.000
D59.8 Other acquired haemolytic anaemias	0.006	0.993	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.006	0.993	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.006	0.993	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.006	0.993	0.000
D59.3 Haemolytic-uraemic syndrome	0.006	0.993	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.006	0.993	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.006	0.994	0.000
D62 Acute posthaemorrhagic anaemia	0.006	0.994	0.000
S48 Traumatic amputation of shoulder and upper arm	0.006	0.994	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.006	0.994	0.000
S47 Crushing injury of shoulder and upper arm	0.006	0.994	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.006	0.994	0.000
T92 Sequelae of injuries of upper limb	0.006	0.994	0.000
C20 Malignant neoplasm of rectum	0.000	0.994	0.006
D73.9 Disease of spleen, unspecified	0.006	0.994	0.000
D57.8 Other sickle-cell disorders	0.006	0.994	0.000
D57.3 Sickle-cell trait	0.006	0.994	0.000
D57.2 Double heterozygous sickling disorders	0.006	0.994	0.000
D57.0 Sickle-cell anaemia with crisis	0.006	0.994	0.000
D74.9 Methaemoglobinaemia, unspecified	0.006	0.994	0.000
D74.8 Other methaemoglobinaemias	0.006	0.994	0.000
D74.0 Congenital methaemoglobinaemia	0.006	0.994	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.006	0.994	0.000
S41.1 Open wound of upper arm	0.006	0.994	0.000
D73.1 Hypersplenism	0.006	0.994	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.006	0.994	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.006	0.994	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.006	0.994	0.000
D56.1 Beta thalassaemia	0.006	0.994	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.006	0.994	0.000
D73.5 Infarction of spleen	0.006	0.994	0.000
D52 Folate deficiency anaemia	0.006	0.994	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.005	0.994	0.000
D55.8 Other anaemias due to enzyme disorders	0.005	0.994	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.005	0.994	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.005	0.994	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.005	0.994	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.005	0.994	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.005	0.994	0.000
D56.9 Thalassaemia, unspecified	0.005	0.994	0.000
D56.8 Other thalassaemias	0.005	0.994	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.005	0.994	0.000
D56.2 Delta-beta thalassaemia	0.005	0.994	0.000
D56.0 Alpha thalassaemia	0.005	0.994	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.005	0.994	0.000
D58.1 Hereditary elliptocytosis	0.005	0.994	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.005	0.995	0.000
D58.0 Hereditary spherocytosis	0.005	0.995	0.000
D53 Other nutritional anaemias	0.005	0.995	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.005	0.995	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.005	0.995	0.000
D73.2 Chronic congestive splenomegaly	0.005	0.995	0.000
S44.2 Injury of radial nerve at upper arm level	0.005	0.995	0.000
D58.2 Other haemoglobinopathies	0.005	0.995	0.000
T92.1 Sequelae of fracture of arm	0.005	0.995	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.005	0.995	0.000
D73.4 Cyst of spleen	0.005	0.995	0.000
D75 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
D52.9 Folate deficiency anaemia, unspecified	0.005	0.995	0.000
M89.5 Osteolysis	0.005	0.995	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.005	0.995	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.005	0.995	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.005	0.995	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.005	0.995	0.000
S44.4 Injury of musculocutaneous nerve	0.005	0.995	0.000
S44.3 Injury of axillary nerve	0.005	0.995	0.000
S44.1 Injury of median nerve at upper arm level	0.005	0.995	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.005	0.995	0.000
D56.3 Thalassaemia trait	0.005	0.995	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.005	0.995	0.000
M89 Other disorders of bone	0.005	0.995	0.000
M89.8 Other specified disorders of bone	0.005	0.995	0.000
S43.0 Dislocation of shoulder joint	0.005	0.995	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.005	0.995	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.005	0.995	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.005	0.995	0.000
S45.2 Injury of axillary or brachial vein	0.005	0.995	0.000
S45.1 Injury of brachial artery	0.005	0.995	0.000
S45.0 Injury of axillary artery	0.005	0.995	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.005	0.995	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.005	0.995	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.005	0.995	0.000
S48.0 Traumatic amputation at shoulder joint	0.005	0.995	0.000
T85.2 Mechanical complication of intraocular lens	0.005	0.995	0.000
M89.3 Hypertrophy of bone	0.005	0.995	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.005	0.995	0.000
D73.8 Other diseases of spleen	0.005	0.995	0.000
S43.4 Sprain and strain of shoulder joint	0.005	0.995	0.000
D73.3 Abscess of spleen	0.005	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.005	0.995	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.005	0.995	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.005	0.995	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.005	0.995	0.000
S43.2 Dislocation of sternoclavicular joint	0.005	0.995	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.005	0.995	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.005	0.995	0.000
M89.83 Other specified disorders of bone (Forearm)	0.005	0.995	0.000
D75.2 Essential thrombocytosis	0.005	0.995	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.995	0.005
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.004	0.996	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.004	0.996	0.000
S46.3 Injury of muscle and tendon of triceps	0.004	0.996	0.000
D52.8 Other folate deficiency anaemias	0.004	0.996	0.000
D52.1 Drug-induced folate deficiency anaemia	0.004	0.996	0.000
D52.0 Dietary folate deficiency anaemia	0.004	0.996	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.004	0.996	0.000
D53.9 Nutritional anaemia, unspecified	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.004	0.996	0.000
I27.0 Primary pulmonary hypertension	0.000	0.996	0.004
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.004	0.996	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.004	0.996	0.000
D53.8 Other specified nutritional anaemias	0.004	0.996	0.000
D53.2 Scorbutic anaemia	0.004	0.996	0.000
D53.0 Protein deficiency anaemia	0.004	0.996	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.004	0.996	0.000
S40 Superficial injury of shoulder and upper arm	0.004	0.996	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.004	0.996	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.004	0.996	0.000
M89.56 Osteolysis (Lower leg)	0.004	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.004	0.996	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.004	0.996	0.000
H61.0 Perichondritis of external ear	0.004	0.996	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.004	0.996	0.000
M89.38 Hypertrophy of bone (Other)	0.004	0.996	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.996	0.004
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.004	0.996	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.004	0.996	0.000
D64 Other anaemias	0.004	0.996	0.000
M89.59 Osteolysis (Site unspecified)	0.004	0.996	0.000
M89.58 Osteolysis (Other)	0.004	0.996	0.000
M89.57 Osteolysis (Ankle and foot)	0.004	0.996	0.000
M89.54 Osteolysis (Hand)	0.004	0.996	0.000
M89.53 Osteolysis (Forearm)	0.004	0.996	0.000
M89.52 Osteolysis (Upper arm)	0.004	0.996	0.000
M89.51 Osteolysis (Shoulder region)	0.004	0.996	0.000
M89.50 Osteolysis (Multiple sites)	0.004	0.996	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.996	0.004
M89.92 Disorder of bone, unspecified (Upper arm)	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.996	0.004
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
S60.8 Other superficial injuries of wrist and hand	0.004	0.996	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.004	0.996	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.004	0.996	0.000
M89.6 Osteopathy after poliomyelitis	0.004	0.996	0.000
M89.2 Other disorders of bone development and growth	0.004	0.996	0.000
M89.1 Epiphyseal arrest	0.004	0.996	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.004	0.996	0.000
M89.04 Algoneurodystrophy (Hand)	0.004	0.996	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.004	0.996	0.000
I27 Other pulmonary heart diseases	0.000	0.996	0.004
D75.1 Secondary polycythaemia	0.004	0.996	0.000
D61 Other aplastic anaemias	0.004	0.996	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.004	0.996	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.004	0.996	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.004	0.996	0.000
M89.34 Hypertrophy of bone (Hand)	0.004	0.996	0.000
M89.33 Hypertrophy of bone (Forearm)	0.004	0.996	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.004	0.996	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.004	0.996	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.004	0.996	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.996	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.996	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.996	0.000
M89.0 Algoneurodystrophy	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.996	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.996	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.996	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.996	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.003	0.997	0.000
H61 Other disorders of external ear	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
N50.8 Other specified disorders of male genital organs	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
D64.8 Other specified anaemias	0.003	0.997	0.000
X49.9 Unspecified place	0.000	0.997	0.003
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S40.0 Contusion of shoulder and upper arm	0.003	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.997	0.003
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
D64.4 Congenital dyserythropoietic anaemia	0.003	0.997	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.997	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
D64.3 Other sideroblastic anaemias	0.003	0.997	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.997	0.003
M89.19 Epiphyseal arrest (Site unspecified)	0.003	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.003	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.003	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.003	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.003	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.003	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.003	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.003	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.003	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.003	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.003	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.003	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.003	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.003	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.003	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.003	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.003	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.003	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.003	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.003	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.003	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.003	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.003	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.003	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.003	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.003	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.003	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.003	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.003	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.003	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.003	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.003	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.003	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.003	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.003	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.997	0.003
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.003	0.997	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.997	0.003
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
H61.3 Acquired stenosis of external ear canal	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.002	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
N30.9 Cystitis, unspecified	0.000	0.997	0.003
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.003	0.997	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.997	0.002
M95.0 Acquired deformity of nose	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
N34.2 Other urethritis	0.000	0.998	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.998	0.002
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
Z13.1 Special screening examination for diabetes mellitus	0.000	0.998	0.002
K51.8 Other ulcerative colitis	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.002	0.998	0.000
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
X49.4 Street and highway	0.000	0.998	0.002
X49.0 Home	0.000	0.998	0.002
X49.8 Other specified place	0.000	0.998	0.002
X49.7 Farm	0.000	0.998	0.002
X49.5 Trade and service area	0.000	0.998	0.002
X49.3 Sports and athletics area	0.000	0.998	0.002
X49.2 School, other institution and public administrative area	0.000	0.998	0.002
X49.1 Residential institution	0.000	0.998	0.002
H60-H62 Diseases of external ear	0.002	0.998	0.000
D07.1 Vulva	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.998	0.002
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
D50 Iron deficiency anaemia	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
X41.9 Unspecified place	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
F64.0 Transsexualism	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.001	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.001	0.998	0.000
F69 Unspecified disorder of adult personality and behaviour	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
F60 Specific personality disorders	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
X49.6 Industrial and construction area	0.000	0.998	0.001
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
W49.0 Home	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
G80.1 Spastic diplegia	0.001	0.998	0.000
J32.8 Other chronic sinusitis	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
K55.8 Other vascular disorders of intestine	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.001	0.998	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.000	0.998	0.001
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.000	0.998	0.001
M21.8 Other specified acquired deformities of limbs	0.001	0.998	0.000
N95.3 States associated with artificial menopause	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.000	0.998	0.001
M21.2 Flexion deformity	0.001	0.998	0.000
N80.1 Endometriosis of ovary	0.000	0.998	0.002
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.001	0.998	0.000
F64 Gender identity disorders	0.000	0.998	0.001
B25.9 Cytomegaloviral disease, unspecified	0.001	0.998	0.000
D50.1 Sideropenic dysphagia	0.001	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.001
T91.3 Sequelae of injury of spinal cord	0.001	0.998	0.000
X68.9 Unspecified place	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations