TreeWAS – Variant ID: rs1534422

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.705	0.295
E03 Other hypothyroidism	0.000	0.948	0.052
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.962	0.038
E03.5 Myxoedema coma	0.000	0.963	0.037
E03.4 Atrophy of thyroid (acquired)	0.000	0.963	0.037
E03.3 Postinfectious hypothyroidism	0.000	0.963	0.037
E03.1 Congenital hypothyroidism without goitre	0.000	0.967	0.033
E03.8 Other specified hypothyroidism	0.000	0.970	0.030
D23.1 Skin of eyelid, including canthus	0.000	0.972	0.028
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.977	0.022
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.987	0.013
A04.8 Other specified bacterial intestinal infections	0.012	0.988	0.000
S83.2 Tear of meniscus, current	0.000	0.990	0.010
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.990	0.010
H53.1 Subjective visual disturbances	0.000	0.991	0.009
I60.9 Subarachnoid haemorrhage, unspecified	0.008	0.992	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.992	0.008
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.992	0.008
S83.0 Dislocation of patella	0.000	0.993	0.007
S83.7 Injury to multiple structures of knee	0.000	0.993	0.006
S83.3 Tear of articular cartilage of knee, current	0.000	0.993	0.006
A41.5 Septicaemia due to other Gram-negative organisms	0.007	0.993	0.000
S83.1 Dislocation of knee	0.000	0.993	0.006
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.994	0.006
G25.0 Essential tremor	0.000	0.994	0.006
S81.8 Open wound of other parts of lower leg	0.000	0.994	0.006
A41.1 Septicaemia due to other specified staphylococcus	0.005	0.995	0.000
A41 Other septicaemia	0.005	0.995	0.000
S81.0 Open wound of knee	0.000	0.995	0.005
S81 Open wound of lower leg	0.000	0.995	0.005
A41.8 Other specified septicaemia	0.005	0.995	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.005	0.995	0.000
H55 Nystagmus and other irregular eye movements	0.005	0.995	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.005	0.995	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
B08.1 Molluscum contagiosum	0.004	0.996	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.996	0.004
A41.3 Septicaemia due to Haemophilus influenzae	0.004	0.996	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.996	0.004
E00-E07 Disorders of thyroid gland	0.000	0.996	0.004
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.004	0.996	0.000
I60 Subarachnoid haemorrhage	0.004	0.996	0.000
S52.01 Fracture of upper end of ulna (open)	0.000	0.996	0.004
E07 Other disorders of thyroid	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.000	0.996	0.004
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
J18.9 Pneumonia, unspecified	0.000	0.996	0.004
C85.1 B-cell lymphoma, unspecified	0.004	0.996	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.996	0.004
A41.0 Septicaemia due to Staphylococcus aureus	0.004	0.996	0.000
A41.4 Septicaemia due to anaerobes	0.003	0.996	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.004	0.996	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.996	0.004
S52.0 Fracture of upper end of ulna	0.000	0.996	0.003
S52.00 Fracture of upper end of ulna (closed)	0.000	0.997	0.003
S80-S89 Injuries to the knee and lower leg	0.000	0.997	0.003
I60.8 Other subarachnoid haemorrhage	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E00 Congenital iodine-deficiency syndrome	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.003	0.997	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.003	0.997	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.997	0.003
E07.1 Dyshormogenetic goitre	0.000	0.997	0.003
E07.0 Hypersecretion of calcitonin	0.000	0.997	0.003
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.003	0.997	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.000	0.997	0.003
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.000	0.997	0.003
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
M47.12 Other spondylosis with myelopathy (Cervical region)	0.003	0.997	0.000
H26.8 Other specified cataract	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.000	0.997	0.003
S86 Injury of muscle and tendon at lower leg level	0.000	0.997	0.003
S52.8 Fracture of other parts of forearm	0.000	0.997	0.003
S88 Traumatic amputation of lower leg	0.000	0.997	0.003
S85 Injury of blood vessels at lower leg level	0.000	0.997	0.003
E06 Thyroiditis	0.000	0.997	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.997	0.003
W02.9 Unspecified place	0.003	0.997	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.997	0.003
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.997	0.003
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.000	0.997	0.002
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.997	0.003
C85.0 Lymphosarcoma	0.002	0.997	0.000
Q61.5 Medullary cystic kidney	0.002	0.997	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.002	0.997	0.000
B08.5 Enteroviral vesicular pharyngitis	0.002	0.997	0.000
B08.4 Enteroviral vesicular stomatitis with exanthem	0.002	0.997	0.000
B08.3 Erythema infectiosum [fifth disease]	0.002	0.997	0.000
B08.2 Exanthema subitum [sixth disease]	0.002	0.997	0.000
B08.0 Other orthopoxvirus infections	0.002	0.997	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.998	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.002	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.000	0.998	0.002
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
A04 Other bacterial intestinal infections	0.002	0.998	0.000
S52.70 Multiple fractures of forearm (closed)	0.000	0.998	0.002
S52.81 Fracture of other parts of forearm (open)	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.000	0.998	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.998	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.998	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.998	0.002
S85.5 Injury of popliteal vein	0.000	0.998	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.998	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.998	0.002
S85.2 Injury of peroneal artery	0.000	0.998	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.998	0.002
S85.0 Injury of popliteal artery	0.000	0.998	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.998	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.998	0.002
S88.0 Traumatic amputation at knee level	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.001
T31 Burns classified according to extent of body surface involved	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.000	0.998	0.002
S52 Fracture of forearm	0.000	0.998	0.002
S89 Other and unspecified injuries of lower leg	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.998	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.998	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.998	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.998	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.998	0.002
B34.8 Other viral infections of unspecified site	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
H53 Visual disturbances	0.000	0.998	0.002
B07 Viral warts	0.002	0.998	0.000
Y04.8 Other specified place	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.000	0.998	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.000	0.998	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
B34.4 Papovirus infection, unspecified	0.000	0.998	0.002
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.998	0.002
S42.1 Fracture of scapula	0.000	0.998	0.002
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
M79.61 Pain in limb (Shoulder region)	0.002	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.002	0.998	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.002	0.998	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.002	0.998	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.002	0.998	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.002
Z76.8 Persons encountering health services in other specified circumstances	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.000	0.998	0.002
S52.6 Fracture of lower end of both ulna and radius	0.000	0.998	0.002
S52.3 Fracture of shaft of radius	0.000	0.998	0.002
T31.9 Burns involving 90% or more of body surface	0.000	0.998	0.002
T31.8 Burns involving 80-89% of body surface	0.000	0.998	0.002
T31.7 Burns involving 70-79% of body surface	0.000	0.998	0.002
T31.6 Burns involving 60-69% of body surface	0.000	0.998	0.002
T31.5 Burns involving 50-59% of body surface	0.000	0.998	0.002
T31.4 Burns involving 40-49% of body surface	0.000	0.998	0.002
T31.3 Burns involving 30-39% of body surface	0.000	0.998	0.002
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
S89.7 Multiple injuries of lower leg	0.000	0.998	0.002
S89.1 Other specified injuries of lower leg	0.000	0.998	0.002
S89.0 Multiple injuries of lower leg	0.000	0.998	0.002
A04.4 Other intestinal Escherichia coli infections	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
H53.6 Night blindness	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
M43.02 Spondylolysis (Cervical region)	0.002	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
W07.0 Home	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
T31.1 Burns involving 10-19% of body surface	0.000	0.998	0.002
S52.71 Multiple fractures of forearm (open)	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
D23.7 Skin of lower limb, including hip	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
H53.5 Colour vision deficiencies	0.000	0.998	0.002
B34 Viral infection of unspecified site	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.998	0.002
G25.5 Other chorea	0.000	0.998	0.002
G25.4 Drug-induced chorea	0.000	0.998	0.002
H53.3 Other disorders of binocular vision	0.000	0.998	0.002
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
B06 Rubella [German measles]	0.002	0.998	0.000
B05 Measles	0.002	0.998	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.002	0.998	0.000
B04 Monkeypox	0.002	0.998	0.000
B03 Smallpox	0.002	0.998	0.000
A04.9 Bacterial intestinal infection, unspecified	0.002	0.998	0.000
H05.2 Exophthalmic conditions	0.000	0.998	0.002
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
T59.8 Other specified gases, fumes and vapours	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
Z76 Persons encountering health services in other circumstances	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.000	0.998	0.001
B01 Varicella [chickenpox]	0.002	0.998	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.002	0.998	0.000
S52.2 Fracture of shaft of ulna	0.000	0.998	0.002
T31.2 Burns involving 20-29% of body surface	0.000	0.998	0.001
S42.11 Fracture of scapula (open)	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
D32.0 Cerebral meninges	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
J35.1 Hypertrophy of tonsils	0.002	0.998	0.000
K14.0 Glossitis	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.001
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.998	0.000
B34.9 Viral infection, unspecified	0.000	0.998	0.002
I95.2 Hypotension due to drugs	0.000	0.998	0.002
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.001
I87 Other disorders of veins	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.000	0.998	0.001
S52.30 Fracture of shaft of radius (closed)	0.000	0.998	0.001
B00.7 Disseminated herpesviral disease	0.001	0.998	0.000
B00.3 Herpesviral meningitis	0.001	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.998	0.001
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.998	0.001
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.000	0.998	0.002
B00.8 Other forms of herpesviral infection	0.001	0.998	0.000
B01.8 Varicella with other complications	0.001	0.998	0.000
G25.1 Drug-induced tremor	0.000	0.998	0.001
M43.0 Spondylolysis	0.002	0.998	0.000
Z54.4 Convalescence following treatment of fracture	0.000	0.998	0.002
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.998	0.001
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.998	0.002
S46.3 Injury of muscle and tendon of triceps	0.000	0.998	0.001
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
B00.0 Eczema herpeticum	0.001	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
S52.21 Fracture of shaft of ulna (open)	0.000	0.998	0.001
B01.2 Varicella pneumonia	0.001	0.998	0.000
B05.9 Measles without complication	0.001	0.998	0.000
B05.8 Measles with other complications	0.001	0.998	0.000
B05.4 Measles with intestinal complications	0.001	0.998	0.000
B05.3 Measles complicated by otitis media	0.001	0.998	0.000
B05.2 Measles complicated by pneumonia	0.001	0.998	0.000
B05.1 Measles complicated by meningitis	0.001	0.998	0.000
B05.0 Measles complicated by encephalitis	0.001	0.998	0.000
B06.9 Rubella without complication	0.001	0.998	0.000
B06.8 Rubella with other complications	0.001	0.998	0.000
B06.0 Rubella with neurological complications	0.001	0.998	0.000
B34.3 Parvovirus infection, unspecified	0.000	0.998	0.001
B34.2 Coronavirus infection, unspecified	0.000	0.998	0.001
B34.1 Enterovirus infection, unspecified	0.000	0.998	0.001
B34.0 Adenovirus infection, unspecified	0.000	0.998	0.001
T39.0 Salicylates	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.000	0.998	0.002
A04.5 Campylobacter enteritis	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
J12.9 Viral pneumonia, unspecified	0.000	0.998	0.001
B01.1 Varicella encephalitis	0.001	0.998	0.000
B01.0 Varicella meningitis	0.001	0.998	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.998	0.001
S89.8 Other specified injuries of lower leg	0.000	0.998	0.001
Z76.5 Malingerer [conscious situation]	0.000	0.998	0.001
Z76.4 Other boarder in health-care facility	0.000	0.998	0.001
Z76.2 Health supervision and care of other healthy infant and child	0.000	0.998	0.001
Z76.1 Health supervision and care of foundling	0.000	0.998	0.001
Z76.0 Issue of repeat prescription	0.000	0.998	0.001
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.001
T13.0 Superficial injury of lower limb, level unspecified	0.000	0.998	0.001
B02.1 Zoster meningitis	0.001	0.999	0.000
Y04.5 Trade and service area	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
G25.3 Myoclonus	0.000	0.999	0.001
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
I87.0 Postphlebitic syndrome	0.000	0.999	0.001
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.999	0.001
M47.1 Other spondylosis with myelopathy	0.001	0.999	0.000
Y04 Assault by bodily force	0.000	0.999	0.001
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.001
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.999	0.001
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.999	0.001
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.001	0.999	0.000
M43.04 Spondylolysis (Thoracic region)	0.001	0.999	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.001	0.999	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.001	0.999	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.001	0.999	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.999	0.001
M06.4 Inflammatory polyarthropathy	0.001	0.999	0.000
Z46.8 Fitting and adjustment of other specified devices	0.000	0.999	0.001
M76.66 Achilles tendinitis (Lower leg)	0.000	0.999	0.001
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.999	0.001
H65.4 Other chronic nonsuppurative otitis media	0.001	0.999	0.000
I87.1 Compression of vein	0.000	0.999	0.001
R07.1 Chest pain on breathing	0.000	0.999	0.001
D86 Sarcoidosis	0.000	0.999	0.001
B02.7 Disseminated zoster	0.001	0.999	0.000
B02.0 Zoster encephalitis	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
H53.8 Other visual disturbances	0.000	0.999	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.999	0.001
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
H55-H59 Other disorders of eye and adnexa	0.001	0.999	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.999	0.001
C77.3 Axillary and upper limb lymph nodes	0.000	0.999	0.001
S52.1 Fracture of upper end of radius	0.000	0.999	0.001
D51 Vitamin B12 deficiency anaemia	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.999	0.001
Y84.0 Cardiac catheterisation	0.001	0.999	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.999	0.000
O12.0 Gestational oedema	0.000	0.999	0.001
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.999	0.001
Y04.9 Unspecified place	0.000	0.999	0.001
Y04.4 Street and highway	0.000	0.999	0.001
Y04.0 Home	0.000	0.999	0.001
Y04.7 Farm	0.000	0.999	0.001
Y04.6 Industrial and construction area	0.000	0.999	0.001
Y04.1 Residential institution	0.000	0.999	0.001
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.001	0.999	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.001	0.999	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.001	0.999	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.001	0.999	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.000	0.999	0.001
B00.4 Herpesviral encephalitis	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
S20.2 Contusion of thorax	0.000	0.999	0.001
Y04.3 Sports and athletics area	0.000	0.999	0.001
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.999	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.999	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.999	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.999	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.999	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.999	0.000
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
Z54.9 Convalescence following unspecified treatment	0.000	0.999	0.001
Z54 Convalescence	0.000	0.999	0.001
B01.9 Varicella without complications	0.001	0.999	0.000
I87.9 Disorder of vein, unspecified	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
Y04.2 School, other institution and public administrative area	0.000	0.999	0.001
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.001	0.999	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.001	0.999	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.999	0.001
A04.7 Enterocolitis due to Clostridium difficile	0.001	0.999	0.000
C83.0 Small cell (diffuse)	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.999	0.001
D51.2 Transcobalamin II deficiency	0.000	0.999	0.001
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.000	0.999	0.001
T51.9 Alcohol, unspecified	0.000	0.999	0.001
X23.9 Unspecified place	0.000	0.999	0.001
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.999	0.001
S52.11 Fracture of upper end of radius (open)	0.000	0.999	0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.999	0.001
N25.8 Other disorders resulting from impaired renal tubular function	0.001	0.999	0.000
Z54.8 Convalescence following other treatment	0.000	0.999	0.001
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.999	0.001
Y86 Sequelae of other accidents	0.000	0.999	0.001
S52.20 Fracture of shaft of ulna (closed)	0.000	0.999	0.001
Y04.09 Assault by bodily force; Home; During unspecified activity	0.000	0.999	0.001
Y04.49 Assault by bodily force; Street and highway; During unspecified activity	0.000	0.999	0.001
Y04.48 Assault by bodily force; Street and highway; While engaged in other specified activities	0.000	0.999	0.001
Y04.99 Assault by bodily force, Unspecified place, During unspecified	0.000	0.999	0.001
D59.1 Other autoimmune haemolytic anaemias	0.000	0.999	0.001
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
D27 Benign neoplasm of ovary	0.000	0.999	0.001
Z54.7 Convalescence following combined treatment	0.000	0.999	0.001
Z54.3 Convalescence following psychotherapy	0.000	0.999	0.001
Z54.2 Convalescence following chemotherapy	0.000	0.999	0.001
Z54.1 Convalescence following radiotherapy	0.000	0.999	0.001
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.999	0.001
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.999	0.001
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.999	0.001
B02.8 Zoster with other complications	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.999	0.000
W02.8 Other specified place	0.001	0.999	0.000
W02.3 Sports and athletics area	0.001	0.999	0.000
W02.7 Farm	0.001	0.999	0.000
W02.6 Industrial and construction area	0.001	0.999	0.000
W02.5 Trade and service area	0.001	0.999	0.000
W02.4 Street and highway	0.001	0.999	0.000
W02.2 School, other institution and public administrative area	0.001	0.999	0.000
W02.1 Residential institution	0.001	0.999	0.000
W02.0 Home	0.001	0.999	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
D43.2 Brain, unspecified	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.999	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.999	0.001
T87.6 Other and unspecified complications of amputation stump	0.000	0.999	0.001
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.999	0.001
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.999	0.001
S43.4 Sprain and strain of shoulder joint	0.000	0.999	0.001
Z76.3 Healthy person accompanying sick person	0.000	0.999	0.001
S40-S49 Injuries to the shoulder and upper arm	0.000	0.999	0.001
D17.9 Benign lipomatous neoplasm, unspecified	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.000	0.999	0.001
W02.31 Fall involving ice-skates, skis, roller-skates or skateboards; Sports and athletics area; While engaged in leisure activity	0.001	0.999	0.000
W02.30 Fall involving ice-skates, skis, roller-skates or skateboards; Sports and athletics area; While engaged in sports activity	0.001	0.999	0.000
W02.81 Fall involving ice-skates, skis, roller-skates or skateboards; Other specified places; While engaged in leisure activity	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.000	0.999	0.001
N08.5 Glomerular disorders in systemic connective tissue disorders	0.000	0.999	0.001
T09.0 Superficial injury of trunk, level unspecified	0.000	0.999	0.001
Z81.8 Family history of other mental and behavioural disorders	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.999	0.001
H20.8 Other iridocyclitis	0.001	0.999	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.001	0.999	0.000
T59.7 Carbon dioxide	0.000	0.999	0.001
T59.6 Hydrogen sulphide	0.000	0.999	0.001
T59.5 Fluorine gas and hydrogen fluoride	0.000	0.999	0.001
T59.4 Chlorine gas	0.000	0.999	0.001
T59.3 Lachrymogenic gas	0.000	0.999	0.001
T59.2 Formaldehyde	0.000	0.999	0.001
T59.1 Sulphur dioxide	0.000	0.999	0.001
T59.0 Nitrogen oxides	0.000	0.999	0.001
S48 Traumatic amputation of shoulder and upper arm	0.000	0.999	0.001
S44 Injury of nerves at shoulder and upper arm level	0.000	0.999	0.001
S47 Crushing injury of shoulder and upper arm	0.000	0.999	0.001
M23.80 Other internal derangements of knee (Multiple sites)	0.001	0.999	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.999	0.001
N02.8 Other	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations