TreeWAS – Variant ID: rs1551678

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.7 Skin of lower limb, including hip	0.012	0.988	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.009	0.991	0.000
Y43.4 Immunosuppressive agents	0.008	0.992	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
Y43.3 Other antineoplastic drugs	0.007	0.993	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.007	0.993	0.000
Y43.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.006	0.994	0.000
Y43.2 Antineoplastic natural products	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
J84 Other interstitial pulmonary diseases	0.006	0.994	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.006	0.994	0.000
Y43.9 Primarily systemic agent, unspecified	0.006	0.994	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.006	0.994	0.000
Y43.6 Enzymes, not elsewhere classified	0.006	0.994	0.000
Y43.5 Acidifying and alkalising agents	0.006	0.994	0.000
O20.0 Threatened abortion	0.000	0.994	0.006
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.005	0.995	0.000
A63.0 Anogenital (venereal) warts	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.995	0.005
D69.6 Thrombocytopenia, unspecified	0.000	0.995	0.005
J84.8 Other specified interstitial pulmonary diseases	0.005	0.995	0.000
D86 Sarcoidosis	0.005	0.995	0.000
J84.0 Alveolar and parietoalveolar conditions	0.005	0.995	0.000
M50.1 Cervical disk disorder with radiculopathy	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.996	0.004
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
K70 Alcoholic liver disease	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.004	0.996	0.000
H26.1 Traumatic cataract	0.000	0.996	0.004
Q65 Congenital deformities of hip	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
M47.80 Other spondylosis (Multiple sites in spine)	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.003	0.996	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
Q66.7 Pes cavus	0.003	0.997	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.003	0.997	0.000
F20 Schizophrenia	0.000	0.997	0.003
S61.0 Open wound of finger(s) without damage to nail	0.000	0.997	0.003
Q70 Syndactyly	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.997	0.003
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
O03.4 Incomplete, without complication	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.997	0.003
J80 Adult respiratory distress syndrome	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.997	0.003
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.003	0.997	0.000
F20.8 Other schizophrenia	0.000	0.997	0.003
F25.9 Schizoaffective disorder, unspecified	0.000	0.997	0.003
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.000	0.997	0.003
M77.9 Enthesopathy, unspecified	0.003	0.997	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
R23.4 Changes in skin texture	0.000	0.997	0.003
D69 Purpura and other haemorrhagic conditions	0.000	0.997	0.003
F23 Acute and transient psychotic disorders	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
F20.5 Residual schizophrenia	0.000	0.997	0.003
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.997	0.000
Q51.3 Bicornate uterus	0.000	0.997	0.003
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.997	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.997	0.000
D81 Combined immunodeficiencies	0.002	0.997	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.002	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.997	0.000
Q79.4 Prune belly syndrome	0.002	0.997	0.000
Q79.3 Gastroschisis	0.002	0.997	0.000
Q79.2 Exomphalos	0.002	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.997	0.000
Q69.9 Polydactyly, unspecified	0.002	0.997	0.000
Q69.2 Accessory toe(s)	0.002	0.997	0.000
Q69.1 Accessory thumb(s)	0.002	0.997	0.000
Q69.0 Accessory finger(s)	0.002	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.997	0.000
Q71.6 Lobster-claw hand	0.002	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.997	0.000
Q72.7 Split foot	0.002	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.997	0.000
Q75.3 Macrocephaly	0.002	0.997	0.000
Q75.2 Hypertelorism	0.002	0.997	0.000
Q75.1 Craniofacial dysostosis	0.002	0.997	0.000
Q75.0 Craniosynostosis	0.002	0.997	0.000
F25 Schizoaffective disorders	0.000	0.997	0.002
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
D69.0 Allergic purpura	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.998	0.002
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.002	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.002
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.998	0.002
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.000	0.998	0.002
J82 Pulmonary eosinophilia, not elsewhere classified	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
Q78.2 Osteopetrosis	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
M43.16 Spondylolisthesis (Lumbar region)	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
F22 Persistent delusional disorders	0.000	0.998	0.002
F28 Other nonorganic psychotic disorders	0.000	0.998	0.002
F24 Induced delusional disorder	0.000	0.998	0.002
C16.9 Stomach, unspecified	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.000	0.998	0.002
K75.0 Abscess of liver	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.002
Q51.4 Unicornate uterus	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.001	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
F21 Schizotypal disorder	0.000	0.998	0.002
D38.2 Pleura	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.002
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.002
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.002
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.002
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.002
A50-A64 Infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.001	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
T42.1 Iminostilbenes	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.002	0.998	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.998	0.002
J34.1 Cyst and mucocele of nose and nasal sinus	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
E29 Testicular dysfunction	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.001
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
A60.0 Herpesviral infection of genitalia and urogenital tract	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
C16.3 Pyloric antrum	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.998	0.000
H66.9 Otitis media, unspecified	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
A52 Late syphilis	0.002	0.998	0.000
K71 Toxic liver disease	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.998	0.000
K71.0 Toxic liver disease with cholestasis	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.000
A59 Trichomoniasis	0.001	0.998	0.000
A56 Other sexually transmitted chlamydial diseases	0.001	0.998	0.000
A54 Gonococcal infection	0.001	0.998	0.000
A53 Other and unspecified syphilis	0.001	0.998	0.000
A51 Early syphilis	0.001	0.998	0.000
A50 Congenital syphilis	0.001	0.998	0.000
A64 Unspecified sexually transmitted disease	0.001	0.998	0.000
A58 Granuloma inguinale	0.001	0.998	0.000
A57 Chancroid	0.001	0.998	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.001	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
E32 Diseases of thymus	0.001	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.001	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.001	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
Q52.5 Fusion of labia	0.000	0.998	0.001
S12.2 Fracture of other specified cervical vertebra	0.001	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.001	0.998	0.000
R73 Elevated blood glucose level	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
A60.9 Anogenital herpesviral infection, unspecified	0.001	0.998	0.000
A60.1 Herpesviral infection of perianal skin and rectum	0.001	0.998	0.000
H31.1 Choroidal degeneration	0.001	0.998	0.000
H31.0 Chorioretinal scars	0.001	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.001	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.998	0.000
E29.8 Other testicular dysfunction	0.001	0.998	0.000
E29.0 Testicular hyperfunction	0.001	0.998	0.000
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
A52.1 Symptomatic neurosyphilis	0.001	0.998	0.000
C16.1 Fundus of stomach	0.001	0.998	0.000
D69.5 Secondary thrombocytopenia	0.000	0.998	0.001
E21.3 Hyperparathyroidism, unspecified	0.001	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.001	0.998	0.000
Q27.4 Congenital phlebectasia	0.001	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.001
K71.9 Toxic liver disease, unspecified	0.001	0.999	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.999	0.001
E25 Adrenogenital disorders	0.001	0.999	0.000
A52.9 Late syphilis, unspecified	0.001	0.999	0.000
A52.8 Late syphilis, latent	0.001	0.999	0.000
A52.7 Other symptomatic late syphilis	0.001	0.999	0.000
A52.3 Neurosyphilis, unspecified	0.001	0.999	0.000
A52.2 Asymptomatic neurosyphilis	0.001	0.999	0.000
A52.0 Cardiovascular syphilis	0.001	0.999	0.000
E24.8 Other Cushing's syndrome	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.000	0.999	0.001
K71.8 Toxic liver disease with other disorders of liver	0.001	0.999	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.001	0.999	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.001	0.999	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.001	0.999	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.001	0.999	0.000
K71.2 Toxic liver disease with acute hepatitis	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.999	0.001
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
E26 Hyperaldosteronism	0.001	0.999	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.999	0.000
D33.3 Cranial nerves	0.001	0.999	0.000
D73.0 Hyposplenism	0.001	0.999	0.000
E32.9 Disease of thymus, unspecified	0.001	0.999	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.999	0.001
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.999	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
A50.9 Congenital syphilis, unspecified	0.001	0.999	0.000
A50.7 Late congenital syphilis, unspecified	0.001	0.999	0.000
A50.6 Late congenital syphilis, latent	0.001	0.999	0.000
A50.5 Other late congenital syphilis, symptomatic	0.001	0.999	0.000
A50.4 Late congenital neurosyphilis [juvenile neurosyphilis]	0.001	0.999	0.000
A50.3 Late congenital syphilitic oculopathy	0.001	0.999	0.000
A50.2 Early congenital syphilis, unspecified	0.001	0.999	0.000
A50.1 Early congenital syphilis, latent	0.001	0.999	0.000
A50.0 Early congenital syphilis, symptomatic	0.001	0.999	0.000
A51.9 Early syphilis, unspecified	0.001	0.999	0.000
A51.5 Early syphilis, latent	0.001	0.999	0.000
A51.4 Other secondary syphilis	0.001	0.999	0.000
A51.3 Secondary syphilis of skin and mucous membranes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations