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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1559831
log Bayes Factor = <0.0001
Chromosome 15   position 39,136,304  (GRCh37) Explore rs1559831 on Ensembl!
Variant rs1559831 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
0.050 0.950 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.047 0.953 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.045 0.955 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.043 0.957 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.043 0.957 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.042 0.958 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.040 0.960 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.039 0.961 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.036 0.964 0.000
M06 Other rheumatoid arthritis
0.035 0.965 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.034 0.966 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.034 0.966 0.000
M06.3 Rheumatoid nodule
0.029 0.971 0.000
M06.4 Inflammatory polyarthropathy
0.028 0.972 0.000
M06.0 Seronegative rheumatoid arthritis
0.026 0.974 0.000
M06.2 Rheumatoid bursitis
0.025 0.975 0.000
M06.1 Adult-onset Still's disease
0.025 0.975 0.000
M06.8 Other specified rheumatoid arthritis
0.025 0.975 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.023 0.977 0.000
M06.34 Rheumatoid nodule (Hand)
0.022 0.978 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.022 0.978 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.022 0.978 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.021 0.979 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.021 0.979 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.021 0.979 0.000
M06.38 Rheumatoid nodule (Other)
0.021 0.979 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.021 0.979 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.021 0.979 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.021 0.979 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.020 0.979 0.000
M06.33 Rheumatoid nodule (Forearm)
0.020 0.979 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.020 0.979 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.020 0.979 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.020 0.979 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.020 0.979 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.020 0.979 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.020 0.979 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.020 0.979 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.020 0.980 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.019 0.980 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.019 0.981 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.019 0.981 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.019 0.981 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.019 0.981 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.019 0.981 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.019 0.981 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.018 0.981 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.018 0.981 0.000
M06.28 Rheumatoid bursitis (Other)
0.018 0.981 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.018 0.981 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.018 0.981 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.018 0.981 0.000
M06.24 Rheumatoid bursitis (Hand)
0.018 0.981 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.018 0.981 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.018 0.981 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.018 0.981 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.018 0.981 0.000
M06.18 Adult-onset Still's disease (Other)
0.018 0.982 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.018 0.982 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.018 0.982 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.018 0.982 0.000
M06.14 Adult-onset Still's disease (Hand)
0.018 0.982 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.018 0.982 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.018 0.982 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.018 0.982 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.018 0.982 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.018 0.982 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.018 0.982 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.018 0.982 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.018 0.982 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.018 0.982 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.018 0.982 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.018 0.982 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.018 0.982 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.017 0.983 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.017 0.983 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.017 0.983 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.017 0.983 0.000
M05-M14 Inflammatory polyarthropathies
0.015 0.985 0.000
M05 Seropositive rheumatoid arthritis
0.013 0.987 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.012 0.988 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.012 0.988 0.000
T43.2 Other and unspecified antidepressants
0.012 0.988 0.000
M12 Other specific arthropathies
0.012 0.988 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.011 0.989 0.000
M08 Juvenile arthritis
0.011 0.989 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.011 0.989 0.000
R18 Ascites
0.011 0.989 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.011 0.989 0.000
M14 Arthropathies in other diseases classified elsewhere
0.011 0.989 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.010 0.990 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.010 0.990 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.010 0.990 0.000
M05.1 Rheumatoid lung disease
0.010 0.990 0.000
M05.8 Other seropositive rheumatoid arthritis
0.010 0.990 0.000
M05.2 Rheumatoid vasculitis
0.010 0.990 0.000
T40.2 Other opioids
0.010 0.990 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.010 0.990 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.010 0.990 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.010 0.990 0.000
M05.0 Felty's syndrome
0.009 0.990 0.000
M10 Gout
0.010 0.990 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.010 0.990 0.000
M11 Other crystal arthropathies
0.009 0.990 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.009 0.990 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.009 0.991 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.009 0.991 0.000
M07 Psoriatic and enteropathic arthropathies
0.009 0.991 0.000
M12.3 Palindromic rheumatism
0.009 0.991 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.009 0.991 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.009 0.991 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.009 0.991 0.000
T43.9 Psychotropic drug, unspecified
0.009 0.991 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.009 0.991 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.009 0.991 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.009 0.991 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.009 0.991 0.000
S82.20 Fracture of shaft of tibia (closed)
0.009 0.991 0.000
T39.0 Salicylates
0.009 0.991 0.000
M12.5 Traumatic arthropathy
0.009 0.991 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.009 0.991 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.009 0.991 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.009 0.991 0.000
M08.0 Juvenile rheumatoid arthritis
0.009 0.991 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.009 0.991 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.009 0.991 0.000
M12.4 Intermittent hydrarthrosis
0.008 0.991 0.000
M12.1 Kaschin-Beck disease
0.008 0.991 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.008 0.991 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.008 0.991 0.000
S82.2 Fracture of shaft of tibia
0.009 0.991 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.008 0.991 0.000
M08.9 Juvenile arthritis, unspecified
0.008 0.991 0.000
M12.2 Villonodular synovitis (pigmented)
0.008 0.991 0.000
T40.6 Other and unspecified narcotics
0.008 0.992 0.000
M13 Other arthritis
0.008 0.992 0.000
T43.6 Psychostimulants with abuse potential
0.008 0.992 0.000
S82 Fracture of lower leg, including ankle
0.008 0.992 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.008 0.992 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.008 0.992 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.008 0.992 0.000
M08.8 Other juvenile arthritis
0.008 0.992 0.000
M08.4 Pauciarticular juvenile arthritis
0.008 0.992 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.008 0.992 0.000
M08.1 Juvenile ankylosing spondylitis
0.008 0.992 0.000
M14.2 Diabetic arthropathy
0.008 0.992 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.008 0.992 0.000
M08.2 Juvenile arthritis with systemic onset
0.008 0.992 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.008 0.992 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.008 0.992 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.008 0.992 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.008 0.992 0.000
M09.0 Juvenile arthritis in psoriasis
0.008 0.992 0.000
T36 Poisoning by systemic antibiotics
0.008 0.992 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.008 0.992 0.000
M14.4 Arthropathy in amyloidosis
0.008 0.992 0.000
M14.3 Lipoid dermatoarthritis
0.008 0.992 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.008 0.992 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.008 0.992 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.008 0.992 0.000
M14.6 Neuropathic arthropathy
0.008 0.992 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.008 0.992 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.008 0.992 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.008 0.992 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.008 0.992 0.000
T40.8 Lysergide [LSD]
0.008 0.992 0.000
T40.7 Cannabis (derivatives)
0.008 0.992 0.000
T40.0 Opium
0.008 0.992 0.000
T40.1 Heroin
0.008 0.992 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.008 0.992 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.008 0.992 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.007 0.992 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.008 0.992 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.007 0.992 0.000
T40.3 Methadone
0.008 0.992 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.008 0.992 0.000
T46.1 Calcium-channel blockers
0.008 0.992 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.007 0.992 0.000
M05.18 Rheumatoid lung disease (Other)
0.007 0.992 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.007 0.992 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.007 0.992 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.007 0.992 0.000
M05.14 Rheumatoid lung disease (Hand)
0.007 0.992 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.007 0.992 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.007 0.992 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.007 0.992 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.007 0.992 0.000
S82.1 Fracture of upper end of tibia
0.008 0.992 0.000
T40.5 Cocaine
0.007 0.992 0.000
T40.4 Other synthetic narcotics
0.007 0.992 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.007 0.992 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.007 0.992 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.007 0.992 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.007 0.992 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.007 0.992 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.007 0.992 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.007 0.992 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.007 0.992 0.000
M13.0 Polyarthritis, unspecified
0.007 0.992 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.007 0.992 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.007 0.993 0.000
M05.28 Rheumatoid vasculitis (Other)
0.007 0.993 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.007 0.993 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.007 0.993 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.007 0.993 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.007 0.993 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.007 0.993 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.007 0.993 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.007 0.993 0.000
S82.3 Fracture of lower end of tibia
0.007 0.993 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.007 0.993 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.007 0.993 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.007 0.993 0.000
M10.3 Gout due to impairment of renal function
0.007 0.993 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.007 0.993 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.007 0.993 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.007 0.993 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.007 0.993 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.007 0.993 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.007 0.993 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.007 0.993 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.007 0.993 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.007 0.993 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.007 0.993 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.007 0.993 0.000
T39.4 Antirheumatics, not elsewhere classified
0.007 0.993 0.000
T39.2 Pyrazolone derivatives
0.007 0.993 0.000
T42.1 Iminostilbenes
0.007 0.993 0.000
M10.0 Idiopathic gout
0.007 0.993 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.007 0.993 0.000
T46.7 Peripheral vasodilators
0.007 0.993 0.000
M11.8 Other specified crystal arthropathies
0.007 0.993 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.007 0.993 0.000
T47.4 Other laxatives
0.007 0.993 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.007 0.993 0.000
M05.08 Felty's syndrome (Other)
0.007 0.993 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.007 0.993 0.000
M05.06 Felty's syndrome (Lower leg)
0.007 0.993 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.007 0.993 0.000
M05.04 Felty's syndrome (Hand)
0.007 0.993 0.000
M05.03 Felty's syndrome (Forearm)
0.007 0.993 0.000
M05.02 Felty's syndrome (Upper arm)
0.007 0.993 0.000
M05.01 Felty's syndrome (Shoulder region)
0.007 0.993 0.000
M05.00 Felty's syndrome (Multiple sites)
0.007 0.993 0.000
M10.4 Other secondary gout
0.007 0.993 0.000
M10.2 Drug-induced gout
0.007 0.993 0.000
M10.1 Lead-induced gout
0.007 0.993 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.007 0.993 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.007 0.993 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.007 0.993 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.007 0.993 0.000
T42.2 Succinimides and oxazolidinediones
0.007 0.993 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.007 0.993 0.000
M07.6 Other enteropathic arthropathies
0.007 0.993 0.000
M11.1 Familial chondrocalcinosis
0.007 0.993 0.000
M11.0 Hydroxyapatite deposition disease
0.007 0.993 0.000
T42.3 Barbiturates
0.007 0.993 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.007 0.993 0.000
M05.09 Felty's syndrome (Site unspecified)
0.007 0.993 0.000
T42.0 Hydantoin derivatives
0.007 0.993 0.000
S82.10 Fracture of upper end of tibia (closed)
0.007 0.993 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.007 0.993 0.000
T47.0 Histamine H(2)-receptor antagonists
0.007 0.993 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.007 0.993 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.007 0.993 0.000
T47.7 Emetics
0.007 0.993 0.000
T47.5 Digestants
0.007 0.993 0.000
T47.3 Saline and osmotic laxatives
0.007 0.993 0.000
T47.2 Stimulant laxatives
0.007 0.993 0.000
S82.30 Fracture of lower end of tibia (closed)
0.007 0.993 0.000
M07.5 Arthropathy in ulcerative colitis
0.007 0.993 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.007 0.993 0.000
M07.2 Psoriatic spondylitis
0.007 0.993 0.000
M07.1 Arthritis mutilans
0.007 0.993 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.007 0.993 0.000
T47.6 Antidiarrhoeal drugs
0.007 0.993 0.000
T45.4 Iron and its compounds
0.007 0.993 0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.007 0.993 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.007 0.993 0.000
M12.38 Palindromic rheumatism (Other)
0.007 0.993 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.007 0.993 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.007 0.993 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.007 0.993 0.000
M12.34 Palindromic rheumatism (Hand)
0.007 0.993 0.000
M12.33 Palindromic rheumatism (Forearm)
0.007 0.993 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.007 0.993 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.007 0.993 0.000
M12.57 Traumatic arthropathy (Ankle and foot)
0.007 0.993 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.007 0.993 0.000
S82.6 Fracture of lateral malleolus
0.007 0.993 0.000
T45.2 Vitamins, not elsewhere classified
0.007 0.993 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.007 0.993 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.007 0.993 0.000
S82.4 Fracture of fibula alone
0.007 0.993 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.007 0.993 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.007 0.993 0.000
T45.8 Other primarily systemic and haematological agents
0.007 0.993 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.007 0.993 0.000
T45.6 Fibrinolysis-affecting drugs
0.007 0.993 0.000
T45.3 Enzymes, not elsewhere classified
0.007 0.993 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.007 0.993 0.000
S82.21 Fracture of shaft of tibia (open)
0.007 0.993 0.000
T92 Sequelae of injuries of upper limb
0.007 0.993 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.007 0.993 0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)
0.006 0.993 0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)
0.006 0.993 0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)
0.006 0.993 0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)
0.006 0.993 0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)
0.006 0.993 0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)
0.006 0.993 0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)
0.006 0.993 0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)
0.006 0.993 0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)
0.006 0.993 0.000
T45.5 Anticoagulants
0.006 0.993 0.000
T82.1 Mechanical complication of cardiac electronic device
0.007 0.993 0.000
M12.59 Traumatic arthropathy (Site unspecified)
0.006 0.993 0.000
M12.58 Traumatic arthropathy (Other)
0.006 0.993 0.000
M12.56 Traumatic arthropathy (Lower leg)
0.006 0.993 0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.006 0.993 0.000
M12.54 Traumatic arthropathy (Hand)
0.006 0.993 0.000
M12.53 Traumatic arthropathy (Forearm)
0.006 0.993 0.000
M12.52 Traumatic arthropathy (Upper arm)
0.006 0.993 0.000
M12.51 Traumatic arthropathy (Shoulder region)
0.006 0.993 0.000
M12.50 Traumatic arthropathy (Multiple sites)
0.006 0.993 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.006 0.993 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.006 0.993 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.006 0.993 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.006 0.993 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.006 0.993 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.006 0.993 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.006 0.993 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.006 0.993 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.007 0.993 0.000
M11.9 Crystal arthropathy, unspecified
0.006 0.993 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.006 0.993 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.993 0.000
T45.0 Antiallergic and antiemetic drugs
0.006 0.993 0.000
S82.5 Fracture of medial malleolus
0.006 0.993 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.006 0.993 0.000
M11.2 Other chondrocalcinosis
0.006 0.993 0.000
S82.9 Fracture of lower leg, part unspecified
0.006 0.993 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.993 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.006 0.993 0.000
T82.3 Mechanical complication of other vascular grafts
0.006 0.993 0.000
S80-S89 Injuries to the knee and lower leg
0.007 0.993 0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.006 0.994 0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.006 0.994 0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.006 0.994 0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.006 0.994 0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.006 0.994 0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.006 0.994 0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)
0.006 0.994 0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)
0.006 0.994 0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)
0.006 0.994 0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)
0.006 0.994 0.000
M12.19 Kaschin-Beck disease (Site unspecified)
0.006 0.994 0.000
M12.18 Kaschin-Beck disease (Other)
0.006 0.994 0.000
M12.17 Kaschin-Beck disease (Ankle and foot)
0.006 0.994 0.000
M12.16 Kaschin-Beck disease (Lower leg)
0.006 0.994 0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)
0.006 0.994 0.000
M12.14 Kaschin-Beck disease (Hand)
0.006 0.994 0.000
M12.13 Kaschin-Beck disease (Forearm)
0.006 0.994 0.000
M12.12 Kaschin-Beck disease (Upper arm)
0.006 0.994 0.000
M12.11 Kaschin-Beck disease (Shoulder region)
0.006 0.994 0.000
M12.10 Kaschin-Beck disease (Multiple sites)
0.006 0.994 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.006 0.994 0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)
0.006 0.994 0.000
M12.48 Intermittent hydrarthrosis (Other)
0.006 0.994 0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)
0.006 0.994 0.000
M12.46 Intermittent hydrarthrosis (Lower leg)
0.006 0.994 0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)
0.006 0.994 0.000
M12.44 Intermittent hydrarthrosis (Hand)
0.006 0.994 0.000
M12.43 Intermittent hydrarthrosis (Forearm)
0.006 0.994 0.000
M12.42 Intermittent hydrarthrosis (Upper arm)
0.006 0.994 0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)
0.006 0.994 0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)
0.006 0.994 0.000
M13.8 Other specified arthritis
0.006 0.994 0.000
M08.98 Juvenile arthritis, unspecified (Other)
0.006 0.994 0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)
0.006 0.994 0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)
0.006 0.994 0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M08.94 Juvenile arthritis, unspecified (Hand)
0.006 0.994 0.000
M08.93 Juvenile arthritis, unspecified (Forearm)
0.006 0.994 0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)
0.006 0.994 0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)
0.006 0.994 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.006 0.994 0.000
T37.5 Antiviral drugs
0.006 0.994 0.000
T37.4 Anthelminthics
0.006 0.994 0.000
T37.3 Other antiprotozoal drugs
0.006 0.994 0.000
T37.1 Antimycobacterial drugs
0.006 0.994 0.000
T37.0 Sulphonamides
0.006 0.994 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.006 0.994 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.006 0.994 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.006 0.994 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.006 0.994 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.006 0.994 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.006 0.994 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.006 0.994 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.006 0.994 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.006 0.994 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.006 0.994 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.006 0.994 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.006 0.994 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.006 0.994 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.006 0.994 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.006 0.994 0.000
T44.0 Anticholinesterase agents
0.006 0.994 0.000
T49.9 Topical agent, unspecified
0.006 0.994 0.000
T49.8 Other topical agents
0.006 0.994 0.000
T49.7 Dental drugs, topically applied
0.006 0.994 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.006 0.994 0.000
T49.5 Ophthalmological drugs and preparations
0.006 0.994 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.006 0.994 0.000
T49.3 Emollients, demulcents and protectants
0.006 0.994 0.000
T49.2 Local astringents and local detergents
0.006 0.994 0.000
T49.1 Antipruritics
0.006 0.994 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.006 0.994 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.006 0.994 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.006 0.994 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.006 0.994 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.006 0.994 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.006 0.994 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.006 0.994 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.006 0.994 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.006 0.994 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.006 0.994 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.006 0.994 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.006 0.994 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.006 0.994 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.006 0.994 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.006 0.994 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.006 0.994 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.006 0.994 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.006 0.994 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.006 0.994 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.006 0.994 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.006 0.994 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.006 0.994 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.006 0.994 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.006 0.994 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.006 0.994 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.006 0.994 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.006 0.994 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.006 0.994 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.006 0.994 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.006 0.994 0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)
0.006 0.994 0.000
M08.89 Other juvenile arthritis (Site unspecified)
0.006 0.994 0.000
M08.88 Other juvenile arthritis (Other)
0.006 0.994 0.000
M08.87 Other juvenile arthritis (Ankle and foot)
0.006 0.994 0.000
M08.86 Other juvenile arthritis (Lower leg)
0.006 0.994 0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)
0.006 0.994 0.000
M08.84 Other juvenile arthritis (Hand)
0.006 0.994 0.000
M08.83 Other juvenile arthritis (Forearm)
0.006 0.994 0.000
M08.82 Other juvenile arthritis (Upper arm)
0.006 0.994 0.000
M08.81 Other juvenile arthritis (Shoulder region)
0.006 0.994 0.000
M08.80 Other juvenile arthritis (Multiple sites)
0.006 0.994 0.000
M47.8 Other spondylosis
0.006 0.994 0.000
M47 Spondylosis
0.006 0.994 0.000
T41.5 Therapeutic gases
0.006 0.994 0.000
T41.4 Anaesthetic, unspecified
0.006 0.994 0.000
T41.3 Local anaesthetics
0.006 0.994 0.000
T41.1 Intravenous anaesthetics
0.006 0.994 0.000
T41.0 Inhaled anaesthetics
0.006 0.994 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.006 0.994 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.006 0.994 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.006 0.994 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.006 0.994 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.006 0.994 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.006 0.994 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.006 0.994 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.006 0.994 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.006 0.994 0.000
T36.8 Other systemic antibiotics
0.006 0.994 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.006 0.994 0.000
T93 Sequelae of injuries of lower limb
0.006 0.994 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.006 0.994 0.000
T90 Sequelae of injuries of head
0.006 0.994 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.006 0.994 0.000
T41.2 Other and unspecified general anaesthetics
0.006 0.994 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.006 0.994 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.006 0.994 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.006 0.994 0.000
T36.9 Systemic antibiotic, unspecified
0.006 0.994 0.000
T36.7 Antifungal antibiotics, systemically used
0.006 0.994 0.000
T36.6 Rifamycins
0.006 0.994 0.000
T36.5 Aminoglycosides
0.006 0.994 0.000
T36.2 Chloramphenicol group
0.006 0.994 0.000
M09.09 Juvenile arthritis in psoriasis (Site unspecified)
0.006 0.994 0.000
M09.08 Juvenile arthritis in psoriasis (Other)
0.006 0.994 0.000
M09.07 Juvenile arthritis in psoriasis (Ankle and foot)
0.006 0.994 0.000
M09.06 Juvenile arthritis in psoriasis (Lower leg)
0.006 0.994 0.000
M09.05 Juvenile arthritis in psoriasis (Pelvic region and thigh)
0.006 0.994 0.000
M09.04 Juvenile arthritis in psoriasis (Hand)
0.006 0.994 0.000
M09.03 Juvenile arthritis in psoriasis (Forearm)
0.006 0.994 0.000
M09.02 Juvenile arthritis in psoriasis (Upper arm)
0.006 0.994 0.000
M09.01 Juvenile arthritis in psoriasis (Shoulder region)
0.006 0.994 0.000
M09.00 Juvenile arthritis in psoriasis (Multiple sites)
0.006 0.994 0.000
M09.19 Juvenile arthritis in Crohn's disease [regional enteritis] (Site unspecified)
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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