TreeWAS – Variant ID: rs1569476

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	0.999	0.001	0.000
D68 Other coagulation defects	0.737	0.263	0.000
D68.6 Other Thrombophilia	0.630	0.370	0.000
D68.5 Primary Thrombophilia	0.583	0.417	0.000
D68.0 Von Willebrand's disease	0.573	0.427	0.000
D68.1 Hereditary factor XI deficiency	0.571	0.429	0.000
D68.8 Other specified coagulation defects	0.545	0.455	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.523	0.477	0.000
D68.4 Acquired coagulation factor deficiency	0.444	0.556	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.395	0.605	0.000
D68.9 Coagulation defect, unspecified	0.377	0.623	0.000
D66 Hereditary factor VIII deficiency	0.315	0.685	0.000
D67 Hereditary factor IX deficiency	0.290	0.709	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.253	0.747	0.000
D69 Purpura and other haemorrhagic conditions	0.246	0.754	0.000
D69.8 Other specified haemorrhagic conditions	0.203	0.797	0.000
D69.0 Allergic purpura	0.202	0.798	0.000
D69.5 Secondary thrombocytopenia	0.200	0.800	0.000
D69.2 Other nonthrombocytopenic purpura	0.195	0.805	0.000
D69.1 Qualitative platelet defects	0.179	0.820	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.178	0.822	0.000
D80-D89 Certain disorders involving the immune mechanism	0.175	0.825	0.000
D86 Sarcoidosis	0.173	0.827	0.000
D69.9 Haemorrhagic condition, unspecified	0.172	0.827	0.000
D86.0 Sarcoidosis of lung	0.161	0.839	0.000
D69.4 Other primary thrombocytopenia	0.160	0.839	0.000
D55-D59 Haemolytic anaemias	0.153	0.847	0.000
D83 Common variable immunodeficiency	0.149	0.851	0.000
D86.3 Sarcoidosis of skin	0.148	0.852	0.000
D86.8 Sarcoidosis of other and combined sites	0.141	0.859	0.000
D86.9 Sarcoidosis, unspecified	0.135	0.865	0.000
D59 Acquired haemolytic anaemia	0.134	0.866	0.000
D80 Immunodeficiency with predominantly antibody defects	0.133	0.867	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.130	0.870	0.000
D83.9 Common variable immunodeficiency, unspecified	0.130	0.870	0.000
D81 Combined immunodeficiencies	0.126	0.874	0.000
D59.1 Other autoimmune haemolytic anaemias	0.126	0.874	0.000
D82 Immunodeficiency associated with other major defects	0.122	0.877	0.000
D86.1 Sarcoidosis of lymph nodes	0.117	0.883	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.114	0.886	0.000
D56 Thalassaemia	0.114	0.886	0.000
D84 Other immunodeficiencies	0.113	0.887	0.000
D55 Anaemia due to enzyme disorders	0.110	0.890	0.000
D58 Other hereditary haemolytic anaemias	0.109	0.891	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.108	0.892	0.000
D83.8 Other common variable immunodeficiencies	0.107	0.893	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.107	0.893	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.107	0.893	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.107	0.893	0.000
D57 Sickle-cell disorders	0.105	0.895	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.103	0.897	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.102	0.898	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.097	0.903	0.000
D59.8 Other acquired haemolytic anaemias	0.096	0.903	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.096	0.903	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.096	0.903	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.096	0.903	0.000
D59.3 Haemolytic-uraemic syndrome	0.096	0.903	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.096	0.903	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.096	0.903	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.096	0.904	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.096	0.904	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.096	0.904	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.096	0.904	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.096	0.904	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.093	0.907	0.000
D81.9 Combined immunodeficiency, unspecified	0.090	0.909	0.000
D81.8 Other combined immunodeficiencies	0.090	0.909	0.000
D81.7 Major histocompatibility complex class II deficiency	0.090	0.909	0.000
D81.6 Major histocompatibility complex class I deficiency	0.090	0.909	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.090	0.909	0.000
D81.4 Nezelof's syndrome	0.090	0.909	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.090	0.909	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.090	0.909	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.090	0.909	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.090	0.909	0.000
D56.1 Beta thalassaemia	0.090	0.910	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.090	0.910	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.088	0.912	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.088	0.912	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.088	0.912	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.088	0.912	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.088	0.912	0.000
D82.2 Immunodeficiency with short-limbed stature	0.088	0.912	0.000
D82.0 Wiskott-Aldrich syndrome	0.088	0.912	0.000
D84.9 Immunodeficiency, unspecified	0.086	0.914	0.000
D82.1 Di George's syndrome	0.084	0.915	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.082	0.918	0.000
D89.3 Immune reconstitution syndrome	0.082	0.918	0.000
D56.9 Thalassaemia, unspecified	0.082	0.918	0.000
D56.8 Other thalassaemias	0.082	0.918	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.082	0.918	0.000
D56.2 Delta-beta thalassaemia	0.082	0.918	0.000
D56.0 Alpha thalassaemia	0.082	0.918	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.081	0.919	0.000
D58.2 Other haemoglobinopathies	0.081	0.919	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.079	0.921	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.079	0.921	0.000
D55.8 Other anaemias due to enzyme disorders	0.079	0.921	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.079	0.921	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.079	0.921	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.079	0.921	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.079	0.921	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.078	0.922	0.000
D58.1 Hereditary elliptocytosis	0.078	0.922	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.078	0.922	0.000
D89.1 Cryoglobulinaemia	0.077	0.922	0.000
D56.3 Thalassaemia trait	0.077	0.923	0.000
D58.0 Hereditary spherocytosis	0.077	0.923	0.000
D57.8 Other sickle-cell disorders	0.076	0.924	0.000
D57.3 Sickle-cell trait	0.076	0.924	0.000
D57.2 Double heterozygous sickling disorders	0.076	0.924	0.000
D57.0 Sickle-cell anaemia with crisis	0.076	0.924	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.075	0.925	0.000
D84.1 Defects in the complement system	0.075	0.925	0.000
D57.1 Sickle-cell anaemia without crisis	0.071	0.928	0.000
D84.8 Other specified immunodeficiencies	0.070	0.930	0.000
D50-D53 Nutritional anaemias	0.063	0.937	0.000
D53 Other nutritional anaemias	0.049	0.951	0.000
D52 Folate deficiency anaemia	0.039	0.961	0.000
D53.9 Nutritional anaemia, unspecified	0.037	0.963	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.037	0.963	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.036	0.964	0.000
D53.8 Other specified nutritional anaemias	0.035	0.965	0.000
D53.2 Scorbutic anaemia	0.035	0.965	0.000
D53.0 Protein deficiency anaemia	0.035	0.965	0.000
D60-D64 Aplastic and other anaemias	0.035	0.965	0.000
D51 Vitamin B12 deficiency anaemia	0.034	0.966	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.969	0.031
D73 Diseases of spleen	0.031	0.969	0.000
D52.8 Other folate deficiency anaemias	0.028	0.971	0.000
D52.1 Drug-induced folate deficiency anaemia	0.028	0.971	0.000
D52.0 Dietary folate deficiency anaemia	0.028	0.971	0.000
D73.0 Hyposplenism	0.027	0.973	0.000
F33 Recurrent depressive disorder	0.000	0.973	0.027
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.026	0.973	0.000
D74 Methaemoglobinaemia	0.026	0.974	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.026	0.974	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.026	0.974	0.000
D73.5 Infarction of spleen	0.026	0.974	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.025	0.975	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.975	0.025
D51.8 Other vitamin B12 deficiency anaemias	0.024	0.975	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.024	0.975	0.000
D51.2 Transcobalamin II deficiency	0.024	0.975	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.024	0.975	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.023	0.976	0.000
D69.6 Thrombocytopenia, unspecified	0.024	0.976	0.000
D73.3 Abscess of spleen	0.023	0.977	0.000
D73.4 Cyst of spleen	0.023	0.977	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.022	0.978	0.000
D73.2 Chronic congestive splenomegaly	0.022	0.978	0.000
D52.9 Folate deficiency anaemia, unspecified	0.022	0.978	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.022	0.978	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.979	0.021
D73.9 Disease of spleen, unspecified	0.021	0.979	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.979	0.021
D60.9 Acquired pure red cell aplasia, unspecified	0.020	0.980	0.000
D73.8 Other diseases of spleen	0.020	0.980	0.000
F33.8 Other recurrent depressive disorders	0.000	0.981	0.019
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.981	0.019
D60.8 Other acquired pure red cell aplasias	0.019	0.981	0.000
D60.1 Transient acquired pure red cell aplasia	0.019	0.981	0.000
D60.0 Chronic acquired pure red cell aplasia	0.019	0.981	0.000
D73.1 Hypersplenism	0.019	0.981	0.000
D63.0 Anaemia in neoplastic disease	0.019	0.981	0.000
D74.9 Methaemoglobinaemia, unspecified	0.019	0.981	0.000
D74.8 Other methaemoglobinaemias	0.019	0.981	0.000
D74.0 Congenital methaemoglobinaemia	0.019	0.981	0.000
D50 Iron deficiency anaemia	0.018	0.982	0.000
F30-F39 Mood [affective] disorders	0.000	0.983	0.017
D63.1 Anaemia in other chronic diseases classified elsewhere	0.016	0.984	0.000
D61 Other aplastic anaemias	0.016	0.984	0.000
D72 Other disorders of white blood cells	0.016	0.984	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.016	0.984	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.016	0.984	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.016	0.984	0.000
D75 Other diseases of blood and blood-forming organs	0.016	0.984	0.000
D50.1 Sideropenic dysphagia	0.016	0.984	0.000
D64 Other anaemias	0.016	0.984	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.015	0.985	0.000
I42.0 Dilated cardiomyopathy	0.014	0.986	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.987	0.013
F32 Depressive episode	0.000	0.987	0.013
F30 Manic episode	0.000	0.987	0.013
F31 Bipolar affective disorder	0.000	0.987	0.013
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.987	0.013
D64.0 Hereditary sideroblastic anaemia	0.013	0.987	0.000
F39 Unspecified mood [affective] disorder	0.000	0.987	0.012
F38 Other mood [affective] disorders	0.000	0.988	0.012
D76.3 Other histiocytosis syndromes	0.012	0.988	0.000
F34 Persistent mood [affective] disorders	0.000	0.988	0.012
D61.8 Other specified aplastic anaemias	0.012	0.988	0.000
D61.3 Idiopathic aplastic anaemia	0.012	0.988	0.000
D61.2 Aplastic anaemia due to other external agents	0.012	0.988	0.000
D62 Acute posthaemorrhagic anaemia	0.012	0.988	0.000
D72.9 Disorder of white blood cells, unspecified	0.012	0.988	0.000
D72.0 Genetic anomalies of leukocytes	0.012	0.988	0.000
D75.2 Essential thrombocytosis	0.012	0.988	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.012	0.988	0.000
F32.0 Mild depressive episode	0.000	0.988	0.012
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.988	0.012
F30.0 Hypomania	0.000	0.989	0.011
D64.4 Congenital dyserythropoietic anaemia	0.011	0.989	0.000
D64.3 Other sideroblastic anaemias	0.011	0.989	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.011	0.989	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.011	0.989	0.000
F32.1 Moderate depressive episode	0.000	0.989	0.011
F30.9 Manic episode, unspecified	0.000	0.989	0.011
D75.0 Familial erythrocytosis	0.011	0.989	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.989	0.011
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.989	0.011
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.011	0.989	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.989	0.011
D61.9 Aplastic anaemia, unspecified	0.010	0.990	0.000
D61.0 Constitutional aplastic anaemia	0.010	0.990	0.000
F30.8 Other manic episodes	0.000	0.990	0.010
I42.9 Cardiomyopathy, unspecified	0.010	0.990	0.000
D72.1 Eosinophilia	0.010	0.990	0.000
D61.1 Drug-induced aplastic anaemia	0.009	0.990	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.990	0.009
I42 Cardiomyopathy	0.010	0.990	0.000
D64.8 Other specified anaemias	0.009	0.991	0.000
N30.9 Cystitis, unspecified	0.000	0.991	0.009
F30.1 Mania without psychotic symptoms	0.000	0.991	0.009
F31.9 Bipolar affective disorder, unspecified	0.000	0.991	0.009
F38.8 Other specified mood [affective] disorders	0.000	0.991	0.009
F38.1 Other recurrent mood [affective] disorders	0.000	0.991	0.009
F38.0 Other single mood [affective] disorders	0.000	0.991	0.009
F31.7 Bipolar affective disorder, currently in remission	0.000	0.991	0.009
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.991	0.009
F34.8 Other persistent mood [affective] disorders	0.000	0.991	0.009
F34.0 Cyclothymia	0.000	0.991	0.009
F32.8 Other depressive episodes	0.000	0.991	0.009
I42.1 Obstructive hypertrophic cardiomyopathy	0.009	0.991	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.009	0.991	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.009	0.991	0.000
F34.1 Dysthymia	0.000	0.991	0.008
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.009	0.991	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.992	0.008
F31.8 Other bipolar affective disorders	0.000	0.992	0.008
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.992	0.008
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.008	0.992	0.000
D75.1 Secondary polycythaemia	0.008	0.992	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.993	0.007
I42.2 Other hypertrophic cardiomyopathy	0.007	0.993	0.000
D50.9 Iron deficiency anaemia, unspecified	0.007	0.993	0.000
I42.5 Other restrictive cardiomyopathy	0.007	0.993	0.000
I42.4 Endocardial fibroelastosis	0.007	0.993	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.007	0.993	0.000
Y44.2 Anticoagulants	0.007	0.993	0.000
F30.2 Mania with psychotic symptoms	0.000	0.993	0.007
S32.40 Fracture of acetabulum (closed)	0.007	0.993	0.000
Z56.6 Other physical and mental strain related to work	0.007	0.993	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.006	0.994	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.006	0.994	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.006	0.994	0.000
D72.8 Other specified disorders of white blood cells	0.006	0.994	0.000
L08 Other local infections of skin and subcutaneous tissue	0.006	0.994	0.000
S32.4 Fracture of acetabulum	0.006	0.994	0.000
Z56 Problems related to employment and unemployment	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
S32 Fracture of lumbar spine and pelvis	0.006	0.994	0.000
Z56.3 Stressful work schedule	0.005	0.995	0.000
D50.8 Other iron deficiency anaemias	0.005	0.995	0.000
K55.2 Angiodysplasia of colon	0.005	0.995	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.995	0.005
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
S32.3 Fracture of ilium	0.005	0.995	0.000
Z57.3 Occupational exposure to other air contaminants	0.005	0.995	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.005	0.995	0.000
N32.3 Diverticulum of bladder	0.005	0.995	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.005	0.995	0.000
S32.30 Fracture of ilium (closed)	0.005	0.995	0.000
I42.6 Alcoholic cardiomyopathy	0.005	0.995	0.000
S31.0 Open wound of lower back and pelvis	0.005	0.995	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.005	0.995	0.000
I42.8 Other cardiomyopathies	0.005	0.995	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.995	0.005
S32.1 Fracture of sacrum	0.005	0.995	0.000
Z56.0 Unemployment, unspecified	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
Z56.7 Other and unspecified problems related to employment	0.005	0.995	0.000
S31 Open wound of abdomen, lower back and pelvis	0.005	0.995	0.000
L08.1 Erythrasma	0.004	0.995	0.000
S30.1 Contusion of abdominal wall	0.005	0.995	0.000
S32.41 Fracture of acetabulum (open)	0.004	0.995	0.000
Z56.5 Uncongenial work	0.004	0.995	0.000
Z56.4 Discord with boss and workmates	0.004	0.995	0.000
Z56.2 Threat of job loss	0.004	0.995	0.000
Z56.1 Change of job	0.004	0.995	0.000
S36 Injury of intra-abdominal organs	0.005	0.995	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.005	0.995	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.004	0.996	0.000
S36.1 Injury of liver or gallbladder	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
S31.4 Open wound of vagina and vulva	0.004	0.996	0.000
Z63 Other problems related to primary support group, including family circumstances	0.004	0.996	0.000
K61.3 Ischiorectal abscess	0.004	0.996	0.000
S32.2 Fracture of coccyx	0.004	0.996	0.000
Z58 Problems related to physical environment	0.004	0.996	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.004	0.996	0.000
L08.0 Pyoderma	0.004	0.996	0.000
S32.10 Fracture of sacrum (closed)	0.004	0.996	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.004	0.996	0.000
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.004	0.996	0.000
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
Z57.7 Occupational exposure to vibration	0.004	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.004	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.004	0.996	0.000
Z57.1 Occupational exposure to radiation	0.004	0.996	0.000
Z57.0 Occupational exposure to noise	0.004	0.996	0.000
S32.31 Fracture of ilium (open)	0.004	0.996	0.000
Z58.8 Other problems related to physical environment	0.004	0.996	0.000
D22.0 Melanocytic naevi of lip	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.004	0.996	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S36.8 Injury of other intra-abdominal organs	0.004	0.996	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.004	0.996	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.004	0.996	0.000
X23.9 Unspecified place	0.000	0.996	0.004
S37 Injury of urinary and pelvic organs	0.004	0.996	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.004	0.996	0.000
Z62 Other problems related to upbringing	0.004	0.996	0.000
Z55 Problems related to education and literacy	0.004	0.996	0.000
Z59 Problems related to housing and economic circumstances	0.004	0.996	0.000
S32.11 Fracture of sacrum (open)	0.003	0.996	0.000
Z61 Problems related to negative life events in childhood	0.004	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.996	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.003	0.996	0.000
S31.3 Open wound of scrotum and testes	0.003	0.996	0.000
S31.5 Open wound of other and unspecified external genital organs	0.003	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.003	0.996	0.000
S36.7 Injury of multiple intra-abdominal organs	0.003	0.996	0.000
S36.6 Injury of rectum	0.003	0.996	0.000
S36.5 Injury of colon	0.003	0.996	0.000
S36.4 Injury of small intestine	0.003	0.996	0.000
S36.3 Injury of stomach	0.003	0.996	0.000
S36.2 Injury of pancreas	0.003	0.996	0.000
Z58.1 Exposure to air pollution	0.003	0.996	0.000
Z65 Problems related to other psychosocial circumstances	0.003	0.996	0.000
S31.2 Open wound of penis	0.003	0.997	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.003	0.997	0.000
U51 Admission status on psychiatric patients	0.000	0.997	0.003
Z64 Problems related to certain psychosocial circumstances	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
Z58.7 Exposure to tobacco smoke	0.003	0.997	0.000
Z63.9 Problem related to primary support group, unspecified	0.003	0.997	0.000
Z63.3 Absence of family member	0.003	0.997	0.000
Z63.2 Inadequate family support	0.003	0.997	0.000
Z63.1 Problems in relationship with parents and in-laws	0.003	0.997	0.000
Z58.9 Problem related to physical environment, unspecified	0.003	0.997	0.000
Z58.6 Inadequate drinking-water supply	0.003	0.997	0.000
Z58.4 Exposure to radiation	0.003	0.997	0.000
Z58.3 Exposure to soil pollution	0.003	0.997	0.000
Z58.2 Exposure to water pollution	0.003	0.997	0.000
Z58.0 Exposure to noise	0.003	0.997	0.000
S32.21 Fracture of coccyx (open)	0.003	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.003	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
X23.0 Home	0.000	0.997	0.003
S36.0 Injury of spleen	0.003	0.997	0.000
Z58.5 Exposure to other pollution	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
Z61.8 Other negative life events in childhood	0.003	0.997	0.000
Z63.6 Dependent relative needing care at home	0.003	0.997	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.003	0.997	0.000
S37.0 Injury of kidney	0.003	0.997	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.003	0.997	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.003	0.997	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.003	0.997	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.003	0.997	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.003	0.997	0.000
S33.5 Sprain and strain of lumbar spine	0.003	0.997	0.000
S33.4 Traumatic rupture of symphysis pubis	0.003	0.997	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.003	0.997	0.000
S33.1 Dislocation of lumbar vertebra	0.003	0.997	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.003	0.997	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.5 Injury of iliac blood vessels	0.003	0.997	0.000
S35.4 Injury of renal blood vessels	0.003	0.997	0.000
S35.3 Injury of portal or splenic vein	0.003	0.997	0.000
S35.2 Injury of coeliac or mesenteric artery	0.003	0.997	0.000
S35.1 Injury of inferior vena cava	0.003	0.997	0.000
S35.0 Injury of abdominal aorta	0.003	0.997	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.997	0.000
S38.2 Traumatic amputation of external genital organs	0.003	0.997	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.997	0.000
S38.0 Crushing injury of external genital organs	0.003	0.997	0.000
Z59.0 Homelessness	0.003	0.997	0.000
S37.9 Injury of unspecified pelvic organ	0.003	0.997	0.000
S37.8 Injury of other pelvic organs	0.003	0.997	0.000
S37.7 Injury of multiple pelvic organs	0.003	0.997	0.000
S37.6 Injury of uterus	0.003	0.997	0.000
S37.5 Injury of Fallopian tube	0.003	0.997	0.000
S37.4 Injury of ovary	0.003	0.997	0.000
S37.1 Injury of ureter	0.003	0.997	0.000
X23 Contact with hornets, wasps and bees	0.000	0.997	0.003
Z59.1 Inadequate housing	0.003	0.997	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.003	0.997	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.003	0.997	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.003	0.997	0.000
S34.4 Injury of lumbosacral plexus	0.003	0.997	0.000
S34.3 Injury of cauda equina	0.003	0.997	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.003	0.997	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.003	0.997	0.000
S37.2 Injury of bladder	0.003	0.997	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.003	0.997	0.000
Z55.8 Other problems relating to education and literacy	0.003	0.997	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.003	0.997	0.000
Z55.3 Underachievement in school	0.003	0.997	0.000
Z55.2 Failed examinations	0.003	0.997	0.000
Z55.1 Schooling unavailable and unattainable	0.003	0.997	0.000
Z55.0 Illiteracy and low-level literacy	0.003	0.997	0.000
Z59.7 Insufficient social insurance and welfare support	0.003	0.997	0.000
Z59.6 Low income	0.003	0.997	0.000
Z59.5 Extreme poverty	0.003	0.997	0.000
Z59.4 Lack of adequate food	0.003	0.997	0.000
Z59.3 Problems related to living in residential institution	0.003	0.997	0.000
Z62.9 Problem related to upbringing, unspecified	0.003	0.997	0.000
Z62.8 Other specified problems related to upbringing	0.003	0.997	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.003	0.997	0.000
Z62.5 Other problems related to neglect in upbringing	0.003	0.997	0.000
Z62.4 Emotional neglect of child	0.003	0.997	0.000
Z62.3 Hostility towards and scapegoating of child	0.003	0.997	0.000
Z62.2 Institutional upbringing	0.003	0.997	0.000
Z62.1 Parental overprotection	0.003	0.997	0.000
Z62.0 Inadequate parental supervision and control	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.003	0.997	0.000
J99.0 Rheumatoid lung disease	0.003	0.997	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.997	0.003
Z61.9 Negative life events in childhood, unspecified	0.003	0.997	0.000
Z61.7 Personal frightening experience in childhood	0.003	0.997	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.003	0.997	0.000
Z61.2 Altered pattern of family relationships in childhood	0.003	0.997	0.000
Z61.1 Removal from home in childhood	0.003	0.997	0.000
Z61.0 Loss of love relationship in childhood	0.003	0.997	0.000
S34.1 Other injury of lumbar spinal cord	0.003	0.997	0.000
S37.3 Injury of urethra	0.003	0.997	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.003	0.997	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.003	0.997	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.003	0.997	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.003	0.997	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.003	0.997	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.003	0.997	0.000
S36.51 Injury of colon (with open wound into cavity)	0.003	0.997	0.000
S36.50 Injury of colon (without open wound into cavity)	0.003	0.997	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.003	0.997	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.003	0.997	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.003	0.997	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.003	0.997	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.003	0.997	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.003	0.997	0.000
Z61.6 Problems related to alleged physical abuse of child	0.003	0.997	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
H21.4 Pupillary membranes	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.003	0.997	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.003	0.997	0.000
Z65.4 Victim of crime and terrorism	0.003	0.997	0.000
Z65.3 Problems related to other legal circumstances	0.003	0.997	0.000
Z65.2 Problems related to release from prison	0.003	0.997	0.000
Z65.1 Imprisonment and other incarceration	0.003	0.997	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.003	0.997	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.003	0.997	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.997	0.003
S32.51 Fracture of pubis (open)	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.997	0.000
Z64.4 Discord with counsellors	0.003	0.997	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.003	0.997	0.000
Z64.1 Problems related to multiparity	0.003	0.997	0.000
H21.0 Hyphaema	0.003	0.997	0.000
S31.1 Open wound of abdominal wall	0.002	0.997	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.997	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
K55.1 Chronic vascular disorders of intestine	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations