TreeWAS – Variant ID: rs1585518

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I42 Cardiomyopathy	0.000	0.781	0.219
I42.0 Dilated cardiomyopathy	0.000	0.787	0.213
I42.9 Cardiomyopathy, unspecified	0.000	0.795	0.205
I42.8 Other cardiomyopathies	0.000	0.800	0.200
I51 Complications and ill-defined descriptions of heart disease	0.000	0.802	0.198
I30-I52 Other forms of heart disease	0.000	0.807	0.193
I51.8 Other ill-defined heart diseases	0.000	0.809	0.191
I51.9 Heart disease, unspecified	0.000	0.823	0.177
I42.2 Other hypertrophic cardiomyopathy	0.000	0.828	0.172
I42.6 Alcoholic cardiomyopathy	0.000	0.830	0.169
I34 Nonrheumatic mitral valve disorders	0.000	0.831	0.169
I31 Other diseases of pericardium	0.000	0.833	0.167
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.834	0.166
I31.9 Disease of pericardium, unspecified	0.000	0.839	0.161
I33 Acute and subacute endocarditis	0.000	0.839	0.161
I51.0 Cardiac septal defect, acquired	0.000	0.840	0.160
I51.7 Cardiomegaly	0.000	0.842	0.158
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.843	0.157
I42.5 Other restrictive cardiomyopathy	0.000	0.843	0.157
I42.4 Endocardial fibroelastosis	0.000	0.843	0.157
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.843	0.157
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.843	0.157
I51.4 Myocarditis, unspecified	0.000	0.847	0.153
I34.1 Mitral (valve) prolapse	0.000	0.851	0.149
I44 Atrioventricular and left bundle-branch block	0.000	0.852	0.148
I44.7 Left bundle-branch block, unspecified	0.000	0.853	0.147
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.854	0.146
I35 Nonrheumatic aortic valve disorders	0.000	0.854	0.146
I30 Acute pericarditis	0.000	0.855	0.145
I51.5 Myocardial degeneration	0.000	0.858	0.142
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.858	0.142
I52 Other heart disorders in diseases classified elsewhere	0.000	0.861	0.139
I48 Atrial fibrillation and flutter	0.000	0.861	0.139
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.861	0.139
I41 Myocarditis in diseases classified elsewhere	0.000	0.861	0.139
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.861	0.139
I32 Pericarditis in diseases classified elsewhere	0.000	0.861	0.139
I33.0 Acute and subacute infective endocarditis	0.000	0.862	0.138
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.863	0.137
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.864	0.136
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.867	0.133
I37 Pulmonary valve disorders	0.000	0.872	0.128
I51.6 Cardiovascular disease, unspecified	0.000	0.872	0.127
I46 Cardiac arrest	0.000	0.874	0.126
I49 Other cardiac arrhythmias	0.000	0.878	0.122
I49.9 Cardiac arrhythmia, unspecified	0.000	0.878	0.122
I45 Other conduction disorders	0.000	0.878	0.122
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.878	0.122
I31.8 Other specified diseases of pericardium	0.000	0.880	0.120
I31.2 Haemopericardium, not elsewhere classified	0.000	0.880	0.120
I31.1 Chronic constrictive pericarditis	0.000	0.880	0.120
I31.0 Chronic adhesive pericarditis	0.000	0.880	0.120
I40 Acute myocarditis	0.000	0.883	0.117
I33.9 Acute endocarditis, unspecified	0.000	0.885	0.115
I30.9 Acute pericarditis, unspecified	0.000	0.887	0.113
I35.0 Aortic (valve) stenosis	0.000	0.891	0.109
I44.5 Left posterior fascicular block	0.000	0.894	0.106
I44.4 Left anterior fascicular block	0.000	0.894	0.106
I46.0 Cardiac arrest with successful resuscitation	0.000	0.895	0.105
I30.8 Other forms of acute pericarditis	0.000	0.896	0.104
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.896	0.104
I36 Nonrheumatic tricuspid valve disorders	0.000	0.897	0.102
I45.1 Other and unspecified right bundle-branch block	0.000	0.898	0.102
I30.1 Infective pericarditis	0.000	0.899	0.101
I49.1 Atrial premature depolarisation	0.000	0.899	0.101
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.900	0.099
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.900	0.099
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.900	0.099
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.900	0.099
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.900	0.099
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.900	0.099
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.900	0.099
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.900	0.099
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.900	0.099
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.900	0.099
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.900	0.099
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.900	0.099
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.900	0.099
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.900	0.099
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.900	0.099
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.900	0.099
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.900	0.099
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.900	0.099
I48.4 Atypical atrial flutter	0.000	0.900	0.099
I48.3 Typical atrial flutter	0.000	0.900	0.099
I48.2 Chronic atrial fibrillation	0.000	0.900	0.099
I48.1 Persistent atrial fibrillation	0.000	0.900	0.099
I48.0 Paroxysmal atrial fibrillation	0.000	0.900	0.099
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.900	0.099
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.900	0.099
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.900	0.099
I44.2 Atrioventricular block, complete	0.000	0.903	0.097
I44.6 Other and unspecified fascicular block	0.000	0.904	0.096
I45.4 Nonspecific intraventricular block	0.000	0.906	0.094
I50 Heart failure	0.000	0.906	0.094
I44.3 Other and unspecified atrioventricular block	0.000	0.906	0.093
I45.2 Bifascicular block	0.000	0.907	0.093
I34.0 Mitral (valve) insufficiency	0.000	0.908	0.092
I37.9 Pulmonary valve disorder, unspecified	0.000	0.908	0.092
I37.8 Other pulmonary valve disorders	0.000	0.908	0.092
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.908	0.092
I37.0 Pulmonary valve stenosis	0.000	0.908	0.092
I46.1 Sudden cardiac death, so described	0.000	0.909	0.091
I35.8 Other aortic valve disorders	0.000	0.910	0.090
I45.3 Trifascicular block	0.000	0.911	0.089
I49.2 Junctional premature depolarisation	0.000	0.912	0.088
I45.0 Right fascicular block	0.000	0.912	0.087
I45.9 Conduction disorder, unspecified	0.000	0.914	0.086
I49.4 Other and unspecified premature depolarisation	0.000	0.915	0.085
I40.9 Acute myocarditis, unspecified	0.000	0.916	0.084
I40.8 Other acute myocarditis	0.000	0.916	0.084
I40.1 Isolated myocarditis	0.000	0.916	0.084
I37.1 Pulmonary valve insufficiency	0.000	0.918	0.081
I38 Endocarditis, valve unspecified	0.000	0.920	0.079
I35.9 Aortic valve disorder, unspecified	0.000	0.922	0.078
I35.1 Aortic (valve) insufficiency	0.000	0.922	0.078
I45.8 Other specified conduction disorders	0.000	0.922	0.077
I50.0 Congestive heart failure	0.000	0.925	0.075
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.001	0.926	0.073
I36.8 Other nonrheumatic tricuspid valve disorders	0.001	0.926	0.073
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.001	0.926	0.073
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.001	0.926	0.073
I47 Paroxysmal tachycardia	0.000	0.928	0.072
I45.6 Preexcitation syndrome	0.000	0.934	0.065
I40.0 Infective myocarditis	0.001	0.937	0.063
I45.5 Other specified heart block	0.000	0.940	0.059
I44.0 Atrioventricular block, first degree	0.000	0.947	0.053
I47.1 Supraventricular tachycardia	0.000	0.948	0.052
I50.9 Heart failure, unspecified	0.000	0.948	0.052
I47.0 Reentry ventricular arrhythmia	0.000	0.949	0.051
I49.5 Sick sinus syndrome	0.000	0.950	0.050
I49.8 Other specified cardiac arrhythmias	0.000	0.950	0.050
I46.9 Cardiac arrest, unspecified	0.000	0.953	0.047
I31.3 Pericardial effusion (noninflammatory)	0.000	0.954	0.046
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.955	0.045
I44.1 Atrioventricular block, second degree	0.000	0.962	0.038
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.001	0.962	0.037
I49.0 Ventricular fibrillation and flutter	0.000	0.963	0.037
I50.1 Left ventricular failure	0.000	0.970	0.030
I49.3 Ventricular premature depolarisation	0.000	0.972	0.028
F31 Bipolar affective disorder	0.015	0.985	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.014	0.986	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.013	0.987	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.013	0.987	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.013	0.987	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.988	0.012
F31.7 Bipolar affective disorder, currently in remission	0.012	0.988	0.000
F31.8 Other bipolar affective disorders	0.012	0.988	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.012	0.988	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.012	0.988	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.012	0.988	0.000
M06.9 Rheumatoid arthritis, unspecified	0.009	0.991	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.009	0.991	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.991	0.009
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.009	0.991	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.991	0.009
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.008	0.992	0.000
I47.2 Ventricular tachycardia	0.001	0.992	0.008
F31.9 Bipolar affective disorder, unspecified	0.008	0.992	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.008	0.992	0.000
C67.9 Bladder, unspecified	0.000	0.992	0.008
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.007	0.993	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.007	0.993	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.007	0.993	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
C67.4 Posterior wall of bladder	0.000	0.993	0.007
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.007	0.993	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
C85.0 Lymphosarcoma	0.000	0.994	0.006
C67 Malignant neoplasm of bladder	0.000	0.994	0.006
K60.3 Anal fistula	0.000	0.994	0.006
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.006	0.994	0.000
C67.5 Bladder neck	0.000	0.994	0.006
K60.1 Chronic anal fissure	0.000	0.994	0.006
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.994	0.005
C67.1 Dome of bladder	0.000	0.995	0.005
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.995	0.005
C67.3 Anterior wall of bladder	0.000	0.995	0.005
C09.9 Tonsil, unspecified	0.005	0.995	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.995	0.005
C67.7 Urachus	0.000	0.995	0.005
C67.0 Trigone of bladder	0.000	0.995	0.005
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
C67.8 Overlapping lesion of bladder	0.000	0.995	0.004
K56.6 Other and unspecified intestinal obstruction	0.000	0.995	0.005
K60.5 Anorectal fistula	0.000	0.996	0.004
M06 Other rheumatoid arthritis	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.004	0.996	0.000
J15.2 Pneumonia due to staphylococcus	0.004	0.996	0.000
C67.6 Ureteric orifice	0.000	0.996	0.004
C09 Malignant neoplasm of tonsil	0.004	0.996	0.000
K60.2 Anal fissure, unspecified	0.000	0.996	0.004
J15 Bacterial pneumonia, not elsewhere classified	0.004	0.996	0.000
K85.9 Acute pancreatitis, unspecified	0.004	0.996	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.004	0.996	0.000
M06.3 Rheumatoid nodule	0.003	0.996	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.997	0.000
M06.2 Rheumatoid bursitis	0.003	0.997	0.000
M06.1 Adult-onset Still's disease	0.003	0.997	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
C02.1 Border of tongue	0.003	0.997	0.000
K60.4 Rectal fistula	0.000	0.997	0.003
C02 Malignant neoplasm of other and unspecified parts of tongue	0.003	0.997	0.000
J15.1 Pneumonia due to Pseudomonas	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.000	0.997	0.003
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
J15.8 Other bacterial pneumonia	0.003	0.997	0.000
J15.5 Pneumonia due to Escherichia coli	0.003	0.997	0.000
M06.4 Inflammatory polyarthropathy	0.003	0.997	0.000
C02.2 Ventral surface of tongue	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
C09.8 Overlapping lesion of tonsil	0.003	0.997	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.003	0.997	0.000
C09.0 Tonsillar fossa	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
J15.9 Bacterial pneumonia, unspecified	0.003	0.997	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.003	0.997	0.000
J15.3 Pneumonia due to streptococcus, group B	0.003	0.997	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
J15.4 Pneumonia due to other streptococci	0.003	0.997	0.000
K60.0 Acute anal fissure	0.000	0.997	0.003
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.997	0.003
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.003	0.997	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.997	0.003
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.997	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.997	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.997	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.997	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.997	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.997	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.997	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.997	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.997	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.002	0.997	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.997	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.997	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.997	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.997	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.997	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.997	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.997	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.997	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.997	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.997	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.997	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.997	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.997	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.997	0.003
C02.8 Overlapping lesion of tongue	0.002	0.997	0.000
C02.4 Lingual tonsil	0.002	0.997	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.002	0.997	0.000
C02.0 Dorsal surface of tongue	0.002	0.997	0.000
C43.5 Malignant melanoma of trunk	0.000	0.997	0.003
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.997	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.997	0.000
L89 Decubitus ulcer	0.003	0.997	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.003	0.997	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.997	0.000
M54.22 Cervicalgia (Cervical region)	0.002	0.997	0.000
J18.9 Pneumonia, unspecified	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
L89.3 Stage IV decubitus ulcer	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.002	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.002	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.002	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.002	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.002	0.998	0.000
D13.1 Stomach	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.002	0.998	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
C11 Malignant neoplasm of nasopharynx	0.002	0.998	0.000
C05 Malignant neoplasm of palate	0.002	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.002	0.998	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.002	0.998	0.000
C03 Malignant neoplasm of gum	0.002	0.998	0.000
C00 Malignant neoplasm of lip	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
J18 Pneumonia, organism unspecified	0.002	0.998	0.000
D41.0 Kidney	0.000	0.998	0.002
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
Z81.8 Family history of other mental and behavioural disorders	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
C08.9 Major salivary gland, unspecified	0.002	0.998	0.000
F34.1 Dysthymia	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
C08.8 Overlapping lesion of major salivary glands	0.002	0.998	0.000
C08.1 Sublingual gland	0.002	0.998	0.000
C08.0 Submandibular gland	0.002	0.998	0.000
C11.9 Nasopharynx, unspecified	0.002	0.998	0.000
H26.4 After-cataract	0.000	0.998	0.002
I85 Oesophageal varices	0.000	0.998	0.002
F30.8 Other manic episodes	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
C11.8 Overlapping lesion of nasopharynx	0.002	0.998	0.000
C11.3 Anterior wall of nasopharynx	0.002	0.998	0.000
C11.2 Lateral wall of nasopharynx	0.002	0.998	0.000
C11.1 Posterior wall of nasopharynx	0.002	0.998	0.000
C11.0 Superior wall of nasopharynx	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
C05.9 Palate, unspecified	0.002	0.998	0.000
C05.8 Overlapping lesion of palate	0.002	0.998	0.000
C05.2 Uvula	0.002	0.998	0.000
C05.1 Soft palate	0.002	0.998	0.000
C05.0 Hard palate	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
C00.9 Lip, unspecified	0.002	0.998	0.000
C00.8 Overlapping lesion of lip	0.002	0.998	0.000
C00.6 Commissure of lip	0.002	0.998	0.000
C00.5 Lip, unspecified, inner aspect	0.002	0.998	0.000
C00.4 Lower lip, inner aspect	0.002	0.998	0.000
C00.3 Upper lip, inner aspect	0.002	0.998	0.000
C00.2 External lip, unspecified	0.002	0.998	0.000
C00.1 External lower lip	0.002	0.998	0.000
C00.0 External upper lip	0.002	0.998	0.000
C03.9 Gum, unspecified	0.002	0.998	0.000
C03.1 Lower gum	0.002	0.998	0.000
C03.0 Upper gum	0.002	0.998	0.000
C06.9 Mouth, unspecified	0.002	0.998	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.002	0.998	0.000
C06.2 Retromolar area	0.002	0.998	0.000
C06.1 Vestibule of mouth	0.002	0.998	0.000
C06.0 Cheek mucosa	0.002	0.998	0.000
C13.9 Hypopharynx, unspecified	0.002	0.998	0.000
C13.8 Overlapping lesion of hypopharynx	0.002	0.998	0.000
C13.2 Posterior wall of hypopharynx	0.002	0.998	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.002	0.998	0.000
C13.0 Postcricoid region	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.001	0.998	0.001
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
C04.8 Overlapping lesion of floor of mouth	0.002	0.998	0.000
C04.1 Lateral floor of mouth	0.002	0.998	0.000
C04.0 Anterior floor of mouth	0.002	0.998	0.000
J09-J18 Influenza and pneumonia	0.002	0.998	0.000
J12 Viral pneumonia, not elsewhere classified	0.002	0.998	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.001
J18.8 Other pneumonia, organism unspecified	0.002	0.998	0.000
J18.2 Hypostatic pneumonia, unspecified	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
C10.8 Overlapping lesion of oropharynx	0.001	0.998	0.000
C10.4 Branchial cleft	0.001	0.998	0.000
C10.3 Posterior wall of oropharynx	0.001	0.998	0.000
C10.2 Lateral wall of oropharynx	0.001	0.998	0.000
C10.1 Anterior surface of epiglottis	0.001	0.998	0.000
C10.0 Vallecula	0.001	0.998	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.001	0.998	0.000
C14.2 Waldeyer's ring	0.001	0.998	0.000
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
J12.2 Parainfluenza virus pneumonia	0.002	0.998	0.000
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
M79.79 Fibromyalgia (Site unspecified)	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
J12.9 Viral pneumonia, unspecified	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
J11 Influenza, virus not identified	0.001	0.998	0.001
J17.1 Pneumonia in viral diseases classified elsewhere	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
L89.2 Stage III decubitus ulcer	0.001	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.002	0.998	0.000
J12.8 Other viral pneumonia	0.001	0.998	0.000
J12.3 Human metapneumovirus pneumonia	0.001	0.998	0.000
J12.1 Respiratory syncytial virus pneumonia	0.001	0.998	0.000
J12.0 Adenoviral pneumonia	0.001	0.998	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.001	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.001	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
C14.0 Pharynx, unspecified	0.001	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.998	0.001
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.001	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.998	0.002
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.001	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.998	0.000
J11.0 Influenza with pneumonia, virus not identified	0.001	0.998	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.001	0.998	0.000
L72.1 Trichilemmal cyst	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.998	0.000
S91.0 Open wound of ankle	0.001	0.998	0.000
J14 Pneumonia due to Haemophilus influenzae	0.001	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
C10.9 Oropharynx, unspecified	0.001	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.001	0.998	0.000
M25.52 Pain in joint (Upper arm)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations