TreeWAS – Variant ID: rs1631486

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H18.5 Hereditary corneal dystrophies	1.000	0.000	0.000
H18 Other disorders of cornea	0.978	0.022	0.000
H18.2 Other corneal oedema	0.899	0.101	0.000
H18.8 Other specified disorders of cornea	0.896	0.104	0.000
H18.4 Corneal degeneration	0.887	0.113	0.000
H18.9 Disorder of cornea, unspecified	0.772	0.228	0.000
H18.3 Changes in corneal membranes	0.761	0.239	0.000
H18.1 Bullous keratopathy	0.724	0.276	0.000
H18.7 Other corneal deformities	0.719	0.281	0.000
H18.6 Keratoconus	0.651	0.349	0.000
H18.0 Corneal pigmentations and deposits	0.614	0.386	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.226	0.774	0.000
H16 Keratitis	0.204	0.796	0.000
H16.0 Corneal ulcer	0.186	0.814	0.000
H16.8 Other keratitis	0.177	0.823	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.823	0.177
H21 Other disorders of iris and ciliary body	0.163	0.837	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.161	0.839	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.155	0.844	0.000
H16.3 Interstitial and deep keratitis	0.153	0.847	0.000
H16.2 Keratoconjunctivitis	0.143	0.857	0.000
H16.4 Corneal neovascularisation	0.141	0.859	0.000
H21.0 Hyphaema	0.135	0.864	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.135	0.865	0.000
H16.9 Keratitis, unspecified	0.134	0.866	0.000
H15 Disorders of sclera	0.134	0.866	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.132	0.868	0.000
H17 Corneal scars and opacities	0.131	0.869	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.127	0.873	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.127	0.873	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.124	0.876	0.000
H21.4 Pupillary membranes	0.121	0.879	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.117	0.883	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.115	0.884	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.115	0.884	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.111	0.888	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.111	0.888	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.105	0.895	0.000
H21.2 Degeneration of iris and ciliary body	0.104	0.896	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.101	0.898	0.000
H15.9 Disorder of sclera, unspecified	0.099	0.900	0.000
H17.1 Other central corneal opacity	0.094	0.906	0.000
H17.0 Adherent leukoma	0.094	0.906	0.000
O47 False labour	0.000	0.909	0.091
H15.1 Episcleritis	0.088	0.912	0.000
H15.0 Scleritis	0.088	0.912	0.000
H17.9 Corneal scar and opacity, unspecified	0.087	0.913	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.916	0.084
H15.8 Other disorders of sclera	0.084	0.916	0.000
H17.8 Other corneal scars and opacities	0.073	0.927	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.071	0.929	0.001
H21.8 Other specified disorders of iris and ciliary body	0.067	0.932	0.000
R07.3 Other chest pain	0.050	0.950	0.000
H20 Iridocyclitis	0.039	0.961	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.036	0.964	0.000
O47.9 False labour, unspecified	0.000	0.969	0.031
H20.2 Lens-induced iridocyclitis	0.028	0.972	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.975	0.025
H20.1 Chronic iridocyclitis	0.021	0.979	0.001
H20.8 Other iridocyclitis	0.020	0.980	0.001
Z29.2 Other prophylactic chemotherapy	0.000	0.980	0.020
H20.0 Acute and subacute iridocyclitis	0.019	0.981	0.001
S68 Traumatic amputation of wrist and hand	0.019	0.981	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.018	0.982	0.000
Z29 Need for other prophylactic measures	0.000	0.983	0.017
S68.0 Traumatic amputation of thumb (complete)(partial)	0.016	0.983	0.000
Z29.0 Isolation	0.000	0.984	0.016
F33 Recurrent depressive disorder	0.015	0.985	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.985	0.015
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.014	0.986	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.014	0.986	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.014	0.986	0.000
S68.4 Traumatic amputation of hand at wrist level	0.014	0.986	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.014	0.986	0.000
H20.9 Iridocyclitis, unspecified	0.013	0.986	0.000
M43.1 Spondylolisthesis	0.000	0.987	0.013
Z29.9 Prophylactic measure, unspecified	0.000	0.987	0.012
F33.0 Recurrent depressive disorder, current episode mild	0.012	0.988	0.000
F33.8 Other recurrent depressive disorders	0.012	0.988	0.000
F33.9 Recurrent depressive disorder, unspecified	0.012	0.988	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.012	0.988	0.000
Z29.8 Other specified prophylactic measures	0.000	0.989	0.011
F33.4 Recurrent depressive disorder, currently in remission	0.011	0.989	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.011	0.989	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.011	0.989	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.990	0.010
R07 Pain in throat and chest	0.010	0.990	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.010	0.990	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.990	0.010
M19.98 Arthrosis, unspecified (Other)	0.010	0.990	0.000
R07.1 Chest pain on breathing	0.010	0.990	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.991	0.009
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.991	0.009
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.991	0.009
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.991	0.009
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.991	0.009
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.991	0.009
R25 Abnormal involuntary movements	0.009	0.991	0.000
M81.9 Osteoporosis, unspecified	0.009	0.991	0.000
M43.12 Spondylolisthesis (Cervical region)	0.000	0.992	0.008
R25.1 Tremor, unspecified	0.008	0.992	0.000
R07.4 Chest pain, unspecified	0.008	0.992	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.008	0.992	0.000
R25.2 Cramp and spasm	0.008	0.992	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.008	0.992	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.008	0.992	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.007	0.992	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.007	0.993	0.000
R25.3 Fasciculation	0.007	0.993	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.007	0.993	0.000
K91.4 Colostomy and enterostomy malfunction	0.007	0.993	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.007	0.993	0.000
L03.9 Cellulitis, unspecified	0.007	0.993	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.993	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.007	0.993	0.000
R25.0 Abnormal head movements	0.007	0.993	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.006	0.993	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.006	0.994	0.000
F39 Unspecified mood [affective] disorder	0.006	0.994	0.000
S00.8 Superficial injury of other parts of head	0.000	0.994	0.006
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
F30-F39 Mood [affective] disorders	0.006	0.994	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.994	0.006
M81.98 Osteoporosis, unspecified (Other)	0.006	0.994	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.005	0.994	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.994	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.005	0.994	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.994	0.000
F30 Manic episode	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
M43 Other deforming dorsopathies	0.000	0.995	0.005
M25.96 Joint disorder, unspecified (Lower leg)	0.005	0.995	0.000
Z99.1 Dependence on respirator	0.005	0.995	0.000
M43.6 Torticollis	0.000	0.995	0.005
F30.1 Mania without psychotic symptoms	0.005	0.995	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.995	0.005
M43.62 Torticollis-Cervical	0.000	0.995	0.005
F38 Other mood [affective] disorders	0.004	0.995	0.000
F34 Persistent mood [affective] disorders	0.005	0.995	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.995	0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
F30.0 Hypomania	0.004	0.995	0.000
Z24 Need for immunisation against certain single viral diseases	0.000	0.996	0.004
Z28 Immunisation not carried out	0.000	0.996	0.004
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.996	0.004
Z25 Need for immunisation against other single viral diseases	0.000	0.996	0.004
Z23 Need for immunisation against single bacterial diseases	0.000	0.996	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.000	0.996	0.004
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
G51.0 Bell's palsy	0.004	0.996	0.000
Z20 Contact with and exposure to communicable diseases	0.000	0.996	0.004
Z26 Need for immunisation against other single infectious diseases	0.000	0.996	0.004
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
F30.8 Other manic episodes	0.004	0.996	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
H01.0 Blepharitis	0.004	0.996	0.000
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.004	0.996	0.000
S51.0 Open wound of elbow	0.004	0.996	0.000
M43.5 Other recurrent vertebral subluxation	0.000	0.996	0.004
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.996	0.004
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.996	0.004
Z22 Carrier of infectious disease	0.000	0.996	0.004
F30.2 Mania with psychotic symptoms	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.004	0.996	0.000
D23.7 Skin of lower limb, including hip	0.000	0.996	0.004
M43.8 Other specified deforming dorsopathies	0.000	0.996	0.004
M43.69 Torticollis-Site unspe	0.000	0.996	0.003
M43.68 Torticollis-Sacral/sacrococ	0.000	0.996	0.003
M43.67 Torticollis-Lumbosacral	0.000	0.996	0.003
M43.66 Torticollis-Lumbar	0.000	0.996	0.003
M43.65 Torticollis-Thoracolumbar	0.000	0.996	0.003
M43.64 Torticollis-Thoracic	0.000	0.996	0.003
M43.63 Torticollis-Cervicothoracic	0.000	0.996	0.003
M43.61 Torticollis-Occipit-atl-axl	0.000	0.996	0.003
M43.60 Torticollis-Mult site	0.000	0.996	0.003
M25.9 Joint disorder, unspecified	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.004	0.996	0.000
F38.8 Other specified mood [affective] disorders	0.003	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.003	0.996	0.000
F38.0 Other single mood [affective] disorders	0.003	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.996	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.996	0.000
F34.0 Cyclothymia	0.003	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.996	0.000
T50.5 Appetite depressants	0.003	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.996	0.000
F34.1 Dysthymia	0.003	0.996	0.000
Z22.5 Carrier of viral hepatitis	0.000	0.996	0.004
M43.9 Deforming dorsopathy, unspecified	0.000	0.996	0.003
Z24.5 Need for immunisation against rubella alone	0.000	0.997	0.003
F30.9 Manic episode, unspecified	0.003	0.997	0.000
Z24.6 Need for immunisation against viral hepatitis	0.000	0.997	0.003
Z24.4 Need for immunisation against measles alone	0.000	0.997	0.003
Z24.3 Need for immunisation against yellow fever	0.000	0.997	0.003
Z24.2 Need for immunisation against rabies	0.000	0.997	0.003
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.000	0.997	0.003
Z24.0 Need for immunisation against poliomyelitis	0.000	0.997	0.003
Z23.8 Need for immunisation against other single bacterial diseases	0.000	0.997	0.003
Z23.7 Need for immunisation against pertussis alone	0.000	0.997	0.003
Z23.6 Need for immunisation against diphtheria alone	0.000	0.997	0.003
Z23.5 Need for immunisation against tetanus alone	0.000	0.997	0.003
Z23.4 Need for immunisation against tularaemia	0.000	0.997	0.003
Z23.3 Need for immunisation against plague	0.000	0.997	0.003
Z23.2 Need for immunisation against tuberculosis [BCG]	0.000	0.997	0.003
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.000	0.997	0.003
Z23.0 Need for immunisation against cholera alone	0.000	0.997	0.003
Z25.8 Need for immunisation against other specified single viral diseases	0.000	0.997	0.003
Z25.1 Need for immunisation against influenza	0.000	0.997	0.003
Z25.0 Need for immunisation against mumps alone	0.000	0.997	0.003
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.000	0.997	0.003
Z27.8 Need for immunisation against other combinations of infectious diseases	0.000	0.997	0.003
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.000	0.997	0.003
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.000	0.997	0.003
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.000	0.997	0.003
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.000	0.997	0.003
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.000	0.997	0.003
Z28.9 Immunisation not carried out for unspecified reason	0.000	0.997	0.003
Z28.8 Immunisation not carried out for other reasons	0.000	0.997	0.003
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.000	0.997	0.003
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.000	0.997	0.003
Z28.0 Immunisation not carried out because of contraindication	0.000	0.997	0.003
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
M43.2 Other fusion of spine	0.000	0.997	0.003
Z22.8 Carrier of other infectious diseases	0.000	0.997	0.003
T50.8 Diagnostic agents	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.000	0.997	0.003
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.000	0.997	0.003
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.000	0.997	0.003
Z20.5 Contact with and exposure to viral hepatitis	0.000	0.997	0.003
Z20.4 Contact with and exposure to rubella	0.000	0.997	0.003
Z20.3 Contact with and exposure to rabies	0.000	0.997	0.003
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.000	0.997	0.003
Z20.0 Contact with and exposure to intestinal infectious diseases	0.000	0.997	0.003
Z26.8 Need for immunisation against other specified single infectious diseases	0.000	0.997	0.003
Z26.0 Need for immunisation against leishmaniasis	0.000	0.997	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
Z20.1 Contact with and exposure to tuberculosis	0.000	0.997	0.003
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
H53.1 Subjective visual disturbances	0.000	0.997	0.003
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.000	0.997	0.003
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.000	0.997	0.003
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.000	0.997	0.003
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.000	0.997	0.003
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.000	0.997	0.003
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.000	0.997	0.003
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.000	0.997	0.003
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.000	0.997	0.003
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.000	0.997	0.003
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.000	0.997	0.003
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.000	0.997	0.003
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.000	0.997	0.003
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.000	0.997	0.003
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.000	0.997	0.003
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.000	0.997	0.003
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.000	0.997	0.003
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.000	0.997	0.003
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.000	0.997	0.003
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.000	0.997	0.003
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.000	0.997	0.003
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.000	0.997	0.003
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.000	0.997	0.003
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.000	0.997	0.003
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.000	0.997	0.003
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.000	0.997	0.003
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.000	0.997	0.003
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.000	0.997	0.003
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.000	0.997	0.003
R86.8 Other abnormal findings	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
Z22.9 Carrier of infectious disease, unspecified	0.000	0.997	0.003
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.997	0.003
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.997	0.003
Z22.2 Carrier of diphtheria	0.000	0.997	0.003
Z22.0 Carrier of typhoid	0.000	0.997	0.003
D50.8 Other iron deficiency anaemias	0.000	0.997	0.003
M25.94 Joint disorder, unspecified (Hand)	0.003	0.997	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.000	0.997	0.003
H47.3 Other disorders of optic disk	0.000	0.997	0.003
Z26.9 Need for immunisation against unspecified infectious disease	0.000	0.997	0.003
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.000	0.997	0.003
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.000	0.997	0.003
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.000	0.997	0.003
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.000	0.997	0.003
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.000	0.997	0.003
M43.82 Other specified deforming dorsopathies (Cervical region)	0.000	0.997	0.003
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.000	0.997	0.003
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.000	0.997	0.003
O21.0 Mild hyperemesis gravidarum	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M25.98 Joint disorder, unspecified (Other)	0.003	0.997	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.003	0.997	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.003	0.997	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.997	0.003
M05.19 Rheumatoid lung disease (Site unspecified)	0.003	0.997	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.003	0.997	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.003	0.997	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.000	0.997	0.002
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.000	0.997	0.002
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.000	0.997	0.002
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.000	0.997	0.002
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.000	0.997	0.002
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.000	0.997	0.002
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.002
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.000	0.997	0.002
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.000	0.997	0.002
M25.97 Joint disorder, unspecified (Ankle and foot)	0.003	0.997	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.997	0.003
F32 Depressive episode	0.003	0.997	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M43.27 Other fusion of spine (Lumbosacral region)	0.000	0.997	0.002
M43.26 Other fusion of spine (Lumbar region)	0.000	0.997	0.002
M43.25 Other fusion of spine (Thoracolumbar region)	0.000	0.997	0.002
M43.24 Other fusion of spine (Thoracic region)	0.000	0.997	0.002
M43.23 Other fusion of spine (Cervicothoracic region)	0.000	0.997	0.002
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.000	0.997	0.002
M43.20 Other fusion of spine (Multiple sites in spine)	0.000	0.997	0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.997	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.997	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.997	0.003
L89.1 Stage II decubitus ulcer	0.003	0.997	0.000
M05.18 Rheumatoid lung disease (Other)	0.002	0.997	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.997	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.997	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.997	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.997	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.997	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.997	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.997	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.997	0.000
M43.0 Spondylolysis	0.000	0.997	0.002
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
H01.1 Non-infectious dermatoses of eyelid	0.003	0.997	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.997	0.000
M05.08 Felty's syndrome (Other)	0.002	0.997	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.997	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.997	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.997	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.997	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.997	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.997	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.997	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.997	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.997	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.997	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.997	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.997	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.997	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.997	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.997	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.997	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.997	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.997	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.997	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.997	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.997	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.997	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.997	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.997	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.997	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.997	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M43.22 Other fusion of spine (Cervical region)	0.000	0.997	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.997	0.002
C18.3 Hepatic flexure	0.000	0.997	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.997	0.000
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
M43.29 Other fusion of spine (Site unspecified)	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.001	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
M13.93 Arthritis, unspecified (Forearm)	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.998	0.002
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.998	0.002
M43.04 Spondylolysis (Thoracic region)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations