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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs164368
log Bayes Factor = <0.0001
Chromosome 5   position 160,624,458  (GRCh37) Explore rs164368 on Ensembl!
Variant rs164368 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.957 0.043
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.959 0.041
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.962 0.038
T43.2 Other and unspecified antidepressants
0.000 0.962 0.038
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.964 0.036
T43.9 Psychotropic drug, unspecified
0.000 0.968 0.032
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.970 0.030
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.970 0.030
T43.6 Psychostimulants with abuse potential
0.000 0.970 0.030
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.973 0.027
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.019 0.981 0.000
M89.9 Disorder of bone, unspecified
0.018 0.982 0.000
M89 Other disorders of bone
0.016 0.984 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.015 0.985 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.015 0.985 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.014 0.985 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.014 0.986 0.000
M86-M90 Other osteopathies
0.014 0.986 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.986 0.014
M89.0 Algoneurodystrophy
0.013 0.986 0.000
M90 Osteopathies in diseases classified elsewhere
0.013 0.987 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.013 0.987 0.000
M88 Paget's disease of bone [osteitis deformans]
0.013 0.987 0.000
M89.98 Disorder of bone, unspecified (Other)
0.013 0.987 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.013 0.987 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.987 0.013
M88.9 Paget's disease of bone, unspecified
0.013 0.987 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.013 0.987 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.013 0.987 0.000
M90.7 Fracture of bone in neoplastic disease
0.013 0.987 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.988 0.012
T36 Poisoning by systemic antibiotics
0.000 0.988 0.012
M89.5 Osteolysis
0.012 0.988 0.000
M89.8 Other specified disorders of bone
0.012 0.988 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.012 0.988 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.012 0.988 0.000
M89.6 Osteopathy after poliomyelitis
0.012 0.988 0.000
M89.2 Other disorders of bone development and growth
0.012 0.988 0.000
M89.1 Epiphyseal arrest
0.012 0.988 0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.012 0.988 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.989 0.011
C67.2 Lateral wall of bladder
0.000 0.989 0.011
M90.78 Fracture of bone in neoplastic disease (Other)
0.011 0.989 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.011 0.989 0.000
T36.0 Penicillins
0.000 0.989 0.011
M89.07 Algoneurodystrophy (Ankle and foot)
0.011 0.989 0.000
M87 Osteonecrosis
0.011 0.989 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.989 0.011
M90.6 Osteitis deformans in neoplastic disease
0.011 0.989 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.011 0.989 0.000
M89.88 Other specified disorders of bone (Other)
0.010 0.990 0.000
M89.3 Hypertrophy of bone
0.010 0.990 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.010 0.990 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.990 0.010
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.990 0.010
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.990 0.010
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.010 0.990 0.000
T50.4 Drugs affecting uric acid metabolism
0.000 0.990 0.010
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.990 0.010
M89.08 Algoneurodystrophy (Other)
0.010 0.990 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.010 0.990 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.010 0.990 0.000
M89.03 Algoneurodystrophy (Forearm)
0.010 0.990 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.010 0.990 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.990 0.010
M90.5 Osteonecrosis in other diseases classified elsewhere
0.010 0.990 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.010 0.990 0.000
M90.3 Osteonecrosis in caisson disease
0.010 0.990 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.010 0.990 0.000
M90.0 Tuberculosis of bone
0.010 0.990 0.000
T36.3 Macrolides
0.000 0.990 0.010
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.990 0.010
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.010 0.990 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.010 0.990 0.000
T50.8 Diagnostic agents
0.000 0.990 0.010
M89.94 Disorder of bone, unspecified (Hand)
0.010 0.990 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.990 0.010
M88.0 Paget's disease of skull
0.009 0.990 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.990 0.009
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.009 0.990 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.990 0.009
T50.5 Appetite depressants
0.000 0.990 0.009
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.990 0.009
T50.0 Mineralocorticoids and their antagonists
0.000 0.990 0.009
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.009 0.990 0.000
M88.98 Paget's disease of bone, unspecified (Other)
0.009 0.990 0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)
0.009 0.990 0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)
0.009 0.990 0.000
M88.94 Paget's disease of bone, unspecified (Hand)
0.009 0.990 0.000
M88.93 Paget's disease of bone, unspecified (Forearm)
0.009 0.990 0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)
0.009 0.990 0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)
0.009 0.990 0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.009 0.991 0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.009 0.991 0.000
M90.74 Fracture of bone in neoplastic disease (Hand)
0.009 0.991 0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.009 0.991 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.009 0.991 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.991 0.009
M88.8 Paget's disease of other bones
0.009 0.991 0.000
M89.83 Other specified disorders of bone (Forearm)
0.009 0.991 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.991 0.009
M87.2 Osteonecrosis due to previous trauma
0.009 0.991 0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)
0.009 0.991 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.991 0.009
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.991 0.009
T36.9 Systemic antibiotic, unspecified
0.000 0.991 0.009
T36.7 Antifungal antibiotics, systemically used
0.000 0.991 0.009
T36.6 Rifamycins
0.000 0.991 0.009
T36.5 Aminoglycosides
0.000 0.991 0.009
T36.2 Chloramphenicol group
0.000 0.991 0.009
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.991 0.009
T45.0 Antiallergic and antiemetic drugs
0.000 0.991 0.009
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)
0.009 0.991 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.009 0.991 0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.009 0.991 0.000
T50.1 Loop [high-ceiling] diuretics
0.000 0.991 0.009
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.009 0.991 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.009 0.991 0.000
T47.0 Histamine H(2)-receptor antagonists
0.000 0.991 0.009
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.991 0.009
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.009 0.991 0.000
T36.8 Other systemic antibiotics
0.000 0.991 0.009
M89.59 Osteolysis (Site unspecified)
0.009 0.991 0.000
M89.58 Osteolysis (Other)
0.009 0.991 0.000
M89.57 Osteolysis (Ankle and foot)
0.009 0.991 0.000
M89.56 Osteolysis (Lower leg)
0.009 0.991 0.000
M89.54 Osteolysis (Hand)
0.009 0.991 0.000
M89.53 Osteolysis (Forearm)
0.009 0.991 0.000
M89.52 Osteolysis (Upper arm)
0.009 0.991 0.000
M89.51 Osteolysis (Shoulder region)
0.009 0.991 0.000
M89.50 Osteolysis (Multiple sites)
0.009 0.991 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.009 0.991 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.009 0.991 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.009 0.991 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.009 0.991 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.009 0.991 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.009 0.991 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.009 0.991 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.009 0.991 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.009 0.991 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.009 0.991 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.009 0.991 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.009 0.991 0.000
T36.4 Tetracyclines
0.000 0.991 0.009
M89.19 Epiphyseal arrest (Site unspecified)
0.008 0.991 0.000
M89.18 Epiphyseal arrest (Other)
0.008 0.991 0.000
M89.17 Epiphyseal arrest (Ankle and foot)
0.008 0.991 0.000
M89.16 Epiphyseal arrest (Lower leg)
0.008 0.991 0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.008 0.991 0.000
M89.14 Epiphyseal arrest (Hand)
0.008 0.991 0.000
M89.13 Epiphyseal arrest (Forearm)
0.008 0.991 0.000
M89.12 Epiphyseal arrest (Upper arm)
0.008 0.991 0.000
M89.11 Epiphyseal arrest (Shoulder region)
0.008 0.991 0.000
M89.10 Epiphyseal arrest (Multiple sites)
0.008 0.991 0.000
M89.29 Other disorders of bone development and growth (Site unspecified)
0.008 0.991 0.000
M89.28 Other disorders of bone development and growth (Other)
0.008 0.991 0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.008 0.991 0.000
M89.26 Other disorders of bone development and growth (Lower leg)
0.008 0.991 0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.008 0.991 0.000
M89.24 Other disorders of bone development and growth (Hand)
0.008 0.991 0.000
M89.23 Other disorders of bone development and growth (Forearm)
0.008 0.991 0.000
M89.22 Other disorders of bone development and growth (Upper arm)
0.008 0.991 0.000
M89.21 Other disorders of bone development and growth (Shoulder region)
0.008 0.991 0.000
M89.20 Other disorders of bone development and growth (Multiple sites)
0.008 0.991 0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.008 0.991 0.000
M89.68 Osteopathy after poliomyelitis (Other)
0.008 0.991 0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.008 0.991 0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.008 0.991 0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.008 0.991 0.000
M89.64 Osteopathy after poliomyelitis (Hand)
0.008 0.991 0.000
M89.63 Osteopathy after poliomyelitis (Forearm)
0.008 0.991 0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.008 0.991 0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.008 0.991 0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.008 0.991 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.008 0.991 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.008 0.991 0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)
0.008 0.991 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.992 0.008
T45.8 Other primarily systemic and haematological agents
0.000 0.992 0.008
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.992 0.008
T45.6 Fibrinolysis-affecting drugs
0.000 0.992 0.008
T45.4 Iron and its compounds
0.000 0.992 0.008
T45.3 Enzymes, not elsewhere classified
0.000 0.992 0.008
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.992 0.008
M87.3 Other secondary osteonecrosis
0.008 0.992 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.992 0.008
M89.81 Other specified disorders of bone (Shoulder region)
0.008 0.992 0.000
T47.2 Stimulant laxatives
0.000 0.992 0.008
M90.89 Osteopathy in other diseases classified elsewhere (Site unspecified)
0.008 0.992 0.000
M90.88 Osteopathy in other diseases classified elsewhere (Other)
0.008 0.992 0.000
M90.87 Osteopathy in other diseases classified elsewhere (Ankle and foot)
0.008 0.992 0.000
M90.86 Osteopathy in other diseases classified elsewhere (Lower leg)
0.008 0.992 0.000
M90.85 Osteopathy in other diseases classified elsewhere (Pelvic region and thigh)
0.008 0.992 0.000
M90.83 Osteopathy in other diseases classified elsewhere (Forearm)
0.008 0.992 0.000
M90.82 Osteopathy in other diseases classified elsewhere (Upper arm)
0.008 0.992 0.000
M90.81 Osteopathy in other diseases classified elsewhere (Shoulder region)
0.008 0.992 0.000
M87.1 Osteonecrosis due to drugs
0.008 0.992 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.008 0.992 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.992 0.008
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.992 0.008
T47.7 Emetics
0.000 0.992 0.008
T47.5 Digestants
0.000 0.992 0.008
T47.3 Saline and osmotic laxatives
0.000 0.992 0.008
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)
0.008 0.992 0.000
M90.68 Osteitis deformans in neoplastic disease (Other)
0.008 0.992 0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)
0.008 0.992 0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)
0.008 0.992 0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)
0.008 0.992 0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)
0.008 0.992 0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)
0.008 0.992 0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)
0.008 0.992 0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)
0.008 0.992 0.000
T47.6 Antidiarrhoeal drugs
0.000 0.992 0.008
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.992 0.008
M89.86 Other specified disorders of bone (Lower leg)
0.008 0.992 0.000
R53 Malaise and fatigue
0.000 0.992 0.008
T45.2 Vitamins, not elsewhere classified
0.000 0.992 0.008
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.992 0.008
M87.9 Osteonecrosis, unspecified
0.008 0.992 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.008 0.992 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.008 0.992 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.008 0.992 0.000
M89.34 Hypertrophy of bone (Hand)
0.008 0.992 0.000
M89.33 Hypertrophy of bone (Forearm)
0.008 0.992 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.008 0.992 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.008 0.992 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.008 0.992 0.000
M89.84 Other specified disorders of bone (Hand)
0.008 0.992 0.000
M89.04 Algoneurodystrophy (Hand)
0.007 0.992 0.000
M86 Osteomyelitis
0.008 0.992 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.008 0.992 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.992 0.007
T37.5 Antiviral drugs
0.000 0.992 0.007
T37.4 Anthelminthics
0.000 0.992 0.007
T37.3 Other antiprotozoal drugs
0.000 0.992 0.007
T37.1 Antimycobacterial drugs
0.000 0.992 0.007
T37.0 Sulphonamides
0.000 0.992 0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.992 0.007
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.992 0.007
T46.7 Peripheral vasodilators
0.000 0.992 0.007
T38.1 Thyroid hormones and substitutes
0.000 0.992 0.007
T47.4 Other laxatives
0.000 0.992 0.007
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.993 0.007
M89.37 Hypertrophy of bone (Ankle and foot)
0.007 0.993 0.000
T39.1 4-Aminophenol derivatives
0.000 0.993 0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.993 0.007
M90.09 Tuberculosis of bone (Site unspecified)
0.007 0.993 0.000
M90.08 Tuberculosis of bone (Other)
0.007 0.993 0.000
M90.07 Tuberculosis of bone (Ankle and foot)
0.007 0.993 0.000
M90.06 Tuberculosis of bone (Lower leg)
0.007 0.993 0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)
0.007 0.993 0.000
M90.04 Tuberculosis of bone (Hand)
0.007 0.993 0.000
M90.03 Tuberculosis of bone (Forearm)
0.007 0.993 0.000
M90.02 Tuberculosis of bone (Upper arm)
0.007 0.993 0.000
M90.01 Tuberculosis of bone (Shoulder region)
0.007 0.993 0.000
M90.00 Tuberculosis of bone (Multiple sites)
0.007 0.993 0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)
0.007 0.993 0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)
0.007 0.993 0.000
M90.27 Osteopathy in other infectious diseases classified elsewhere (Ankle and foot)
0.007 0.993 0.000
M90.26 Osteopathy in other infectious diseases classified elsewhere (Lower leg)
0.007 0.993 0.000
M90.25 Osteopathy in other infectious diseases classified elsewhere (Pelvic region and thigh)
0.007 0.993 0.000
M90.24 Osteopathy in other infectious diseases classified elsewhere (Hand)
0.007 0.993 0.000
M90.23 Osteopathy in other infectious diseases classified elsewhere (Forearm)
0.007 0.993 0.000
M90.22 Osteopathy in other infectious diseases classified elsewhere (Upper arm)
0.007 0.993 0.000
M90.21 Osteopathy in other infectious diseases classified elsewhere (Shoulder region)
0.007 0.993 0.000
M90.20 Osteopathy in other infectious diseases classified elsewhere (Multiple sites)
0.007 0.993 0.000
M90.39 Osteonecrosis in caisson disease (Site unspecified)
0.007 0.993 0.000
M90.38 Osteonecrosis in caisson disease (Other)
0.007 0.993 0.000
M90.37 Osteonecrosis in caisson disease (Ankle and foot)
0.007 0.993 0.000
M90.36 Osteonecrosis in caisson disease (Lower leg)
0.007 0.993 0.000
M90.35 Osteonecrosis in caisson disease (Pelvic region and thigh)
0.007 0.993 0.000
M90.34 Osteonecrosis in caisson disease (Hand)
0.007 0.993 0.000
M90.33 Osteonecrosis in caisson disease (Forearm)
0.007 0.993 0.000
M90.32 Osteonecrosis in caisson disease (Upper arm)
0.007 0.993 0.000
M90.31 Osteonecrosis in caisson disease (Shoulder region)
0.007 0.993 0.000
M90.30 Osteonecrosis in caisson disease (Multiple sites)
0.007 0.993 0.000
M90.49 Osteonecrosis due to haemoglobinopathy (Site unspecified)
0.007 0.993 0.000
M90.48 Osteonecrosis due to haemoglobinopathy (Other)
0.007 0.993 0.000
M90.47 Osteonecrosis due to haemoglobinopathy (Ankle and foot)
0.007 0.993 0.000
M90.46 Osteonecrosis due to haemoglobinopathy (Lower leg)
0.007 0.993 0.000
M90.45 Osteonecrosis due to haemoglobinopathy (Pelvic region and thigh)
0.007 0.993 0.000
M90.44 Osteonecrosis due to haemoglobinopathy (Hand)
0.007 0.993 0.000
M90.43 Osteonecrosis due to haemoglobinopathy (Forearm)
0.007 0.993 0.000
M90.42 Osteonecrosis due to haemoglobinopathy (Upper arm)
0.007 0.993 0.000
M90.41 Osteonecrosis due to haemoglobinopathy (Shoulder region)
0.007 0.993 0.000
M90.40 Osteonecrosis due to haemoglobinopathy (Multiple sites)
0.007 0.993 0.000
M90.59 Osteonecrosis in other diseases classified elsewhere (Site unspecified)
0.007 0.993 0.000
M90.58 Osteonecrosis in other diseases classified elsewhere (Other)
0.007 0.993 0.000
M90.57 Osteonecrosis in other diseases classified elsewhere (Ankle and foot)
0.007 0.993 0.000
M90.56 Osteonecrosis in other diseases classified elsewhere (Lower leg)
0.007 0.993 0.000
M90.55 Osteonecrosis in other diseases classified elsewhere (Pelvic region and thigh)
0.007 0.993 0.000
M90.54 Osteonecrosis in other diseases classified elsewhere (Hand)
0.007 0.993 0.000
M90.53 Osteonecrosis in other diseases classified elsewhere (Forearm)
0.007 0.993 0.000
M90.52 Osteonecrosis in other diseases classified elsewhere (Upper arm)
0.007 0.993 0.000
M90.51 Osteonecrosis in other diseases classified elsewhere (Shoulder region)
0.007 0.993 0.000
M90.50 Osteonecrosis in other diseases classified elsewhere (Multiple sites)
0.007 0.993 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.993 0.007
T48.4 Expectorants
0.000 0.993 0.007
T48.3 Antitussives
0.000 0.993 0.007
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.993 0.007
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.993 0.007
T48.0 Oxytocic drugs
0.000 0.993 0.007
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.007 0.993 0.000
T41.5 Therapeutic gases
0.000 0.993 0.007
T41.4 Anaesthetic, unspecified
0.000 0.993 0.007
T41.3 Local anaesthetics
0.000 0.993 0.007
T41.1 Intravenous anaesthetics
0.000 0.993 0.007
T41.0 Inhaled anaesthetics
0.000 0.993 0.007
M88.09 Paget's disease of skull-Site unspec
0.007 0.993 0.000
M88.08 Paget's disease of skull-Other
0.007 0.993 0.000
M88.07 Paget's disease of skull-Ankle/Foot
0.007 0.993 0.000
M88.06 Paget's disease of skull-Lower Leg
0.007 0.993 0.000
M88.05 Paget's disease of skull-Pelvic/Thigh
0.007 0.993 0.000
M88.04 Paget's disease of skull-Hand
0.007 0.993 0.000
M88.03 Paget's disease of skull-Forearm
0.007 0.993 0.000
M88.02 Paget's disease of skull-Upper arm
0.007 0.993 0.000
M88.01 Paget's disease of skull-Shldr region
0.007 0.993 0.000
M88.00 Paget's disease of skull-Mult sites
0.007 0.993 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.007 0.993 0.001
T40.1 Heroin
0.000 0.993 0.007
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.993 0.007
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.993 0.007
T38.9 Other and unspecified hormone antagonists
0.000 0.993 0.007
T38.7 Androgens and anabolic congeners
0.000 0.993 0.007
T38.5 Other oestrogens and progestogens
0.000 0.993 0.007
T38.4 Oral contraceptives
0.000 0.993 0.007
T38.2 Antithyroid drugs
0.000 0.993 0.007
T48.5 Anti-common-cold drugs
0.000 0.993 0.007
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)
0.007 0.993 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.007 0.993 0.000
M88.89 Paget's disease of other bones (Site unspecified)
0.007 0.993 0.000
M88.87 Paget's disease of other bones (Ankle and foot)
0.007 0.993 0.000
M88.86 Paget's disease of other bones (Lower leg)
0.007 0.993 0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)
0.007 0.993 0.000
M88.84 Paget's disease of other bones (Hand)
0.007 0.993 0.000
M88.83 Paget's disease of other bones (Forearm)
0.007 0.993 0.000
M88.82 Paget's disease of other bones (Upper arm)
0.007 0.993 0.000
M88.81 Paget's disease of other bones (Shoulder region)
0.007 0.993 0.000
M88.80 Paget's disease of other bones (Multiple sites)
0.007 0.993 0.000
M87.8 Other osteonecrosis
0.007 0.993 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.993 0.007
T49.9 Topical agent, unspecified
0.000 0.993 0.007
T49.8 Other topical agents
0.000 0.993 0.007
T49.7 Dental drugs, topically applied
0.000 0.993 0.007
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.993 0.007
T49.5 Ophthalmological drugs and preparations
0.000 0.993 0.007
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.993 0.007
T49.3 Emollients, demulcents and protectants
0.000 0.993 0.007
T49.2 Local astringents and local detergents
0.000 0.993 0.007
T49.1 Antipruritics
0.000 0.993 0.007
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.007 0.993 0.000
M87.28 Osteonecrosis due to previous trauma (Other)
0.007 0.993 0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.007 0.993 0.000
M87.24 Osteonecrosis due to previous trauma (Hand)
0.007 0.993 0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.007 0.993 0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.007 0.993 0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.007 0.993 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.993 0.007
M89.38 Hypertrophy of bone (Other)
0.007 0.993 0.000
T40.5 Cocaine
0.000 0.993 0.007
T40.2 Other opioids
0.000 0.993 0.007
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.993 0.007
T40.8 Lysergide [LSD]
0.000 0.993 0.007
T40.7 Cannabis (derivatives)
0.000 0.993 0.007
T40.3 Methadone
0.000 0.993 0.007
T40.0 Opium
0.000 0.993 0.007
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.993 0.007
T39.4 Antirheumatics, not elsewhere classified
0.000 0.993 0.007
T39.2 Pyrazolone derivatives
0.000 0.993 0.007
T41.2 Other and unspecified general anaesthetics
0.000 0.993 0.006
T38.0 Glucocorticoids and synthetic analogues
0.000 0.993 0.006
M88.88 Paget's disease of other bones (Other)
0.006 0.993 0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)
0.006 0.993 0.000
M90.19 Periostitis in other infectious diseases classified elsewhere (Site unspecified)
0.006 0.994 0.000
M90.18 Periostitis in other infectious diseases classified elsewhere (Other)
0.006 0.994 0.000
M90.17 Periostitis in other infectious diseases classified elsewhere (Ankle and foot)
0.006 0.994 0.000
M90.16 Periostitis in other infectious diseases classified elsewhere (Lower leg)
0.006 0.994 0.000
M90.15 Periostitis in other infectious diseases classified elsewhere (Pelvic region and thigh)
0.006 0.994 0.000
M90.14 Periostitis in other infectious diseases classified elsewhere (Hand)
0.006 0.994 0.000
M90.13 Periostitis in other infectious diseases classified elsewhere (Forearm)
0.006 0.994 0.000
M90.12 Periostitis in other infectious diseases classified elsewhere (Upper arm)
0.006 0.994 0.000
M90.11 Periostitis in other infectious diseases classified elsewhere (Shoulder region)
0.006 0.994 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.994 0.006
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)
0.006 0.994 0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)
0.006 0.994 0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)
0.006 0.994 0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)
0.006 0.994 0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)
0.006 0.994 0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)
0.006 0.994 0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)
0.006 0.994 0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)
0.006 0.994 0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)
0.006 0.994 0.000
T45.5 Anticoagulants
0.000 0.994 0.006
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.994 0.006
M87.39 Other secondary osteonecrosis (Site unspecified)
0.006 0.994 0.000
M87.38 Other secondary osteonecrosis (Other)
0.006 0.994 0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)
0.006 0.994 0.000
M87.36 Other secondary osteonecrosis (Lower leg)
0.006 0.994 0.000
M87.34 Other secondary osteonecrosis (Hand)
0.006 0.994 0.000
M87.33 Other secondary osteonecrosis (Forearm)
0.006 0.994 0.000
M87.32 Other secondary osteonecrosis (Upper arm)
0.006 0.994 0.000
M87.31 Other secondary osteonecrosis (Shoulder region)
0.006 0.994 0.000
M87.30 Other secondary osteonecrosis (Multiple sites)
0.006 0.994 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.994 0.006
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.006 0.994 0.000
T40.4 Other synthetic narcotics
0.000 0.994 0.006
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)
0.006 0.994 0.000
A08.4 Viral intestinal infection, unspecified
0.006 0.994 0.000
S52.6 Fracture of lower end of both ulna and radius
0.006 0.994 0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)
0.006 0.994 0.000
M87.18 Osteonecrosis due to drugs (Other)
0.006 0.994 0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)
0.006 0.994 0.000
M87.16 Osteonecrosis due to drugs (Lower leg)
0.006 0.994 0.000
M87.14 Osteonecrosis due to drugs (Hand)
0.006 0.994 0.000
M87.13 Osteonecrosis due to drugs (Forearm)
0.006 0.994 0.000
M87.12 Osteonecrosis due to drugs (Upper arm)
0.006 0.994 0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)
0.006 0.994 0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)
0.006 0.994 0.000
M86.8 Other osteomyelitis
0.006 0.994 0.000
M86.6 Other chronic osteomyelitis
0.006 0.994 0.000
L43.9 Lichen planus, unspecified
0.006 0.994 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.006 0.994 0.000
M86.1 Other acute osteomyelitis
0.006 0.994 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.994 0.006
J69.0 Pneumonitis due to food and vomit
0.000 0.994 0.006
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.006 0.994 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.006 0.994 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.006 0.994 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.006 0.994 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.006 0.994 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.006 0.994 0.000
M86.3 Chronic multifocal osteomyelitis
0.006 0.994 0.000
M86.2 Subacute osteomyelitis
0.006 0.994 0.000
M86.0 Acute haematogenous osteomyelitis
0.006 0.994 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.994 0.006
T40.6 Other and unspecified narcotics
0.000 0.994 0.006
M87.96 Osteonecrosis, unspecified (Lower leg)
0.006 0.994 0.000
T46.1 Calcium-channel blockers
0.000 0.994 0.005
E66.8 Other obesity
0.000 0.994 0.006
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.994 0.005
S52.61 Fracture of lower end of both ulna and radius (open)
0.005 0.994 0.000
M87.86 Other osteonecrosis (Lower leg)
0.005 0.994 0.000
M47.86 Other spondylosis (Lumbar region)
0.000 0.995 0.005
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.005 0.995 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.005 0.995 0.000
M87.89 Other osteonecrosis (Site unspecified)
0.005 0.995 0.000
M87.88 Other osteonecrosis (Other)
0.005 0.995 0.000
M87.87 Other osteonecrosis (Ankle and foot)
0.005 0.995 0.000
M87.84 Other osteonecrosis (Hand)
0.005 0.995 0.000
M87.83 Other osteonecrosis (Forearm)
0.005 0.995 0.000
M87.82 Other osteonecrosis (Upper arm)
0.005 0.995 0.000
M87.81 Other osteonecrosis (Shoulder region)
0.005 0.995 0.000
M87.80 Other osteonecrosis (Multiple sites)
0.005 0.995 0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)
0.005 0.995 0.000
M86.68 Other chronic osteomyelitis (Other)
0.005 0.995 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.005 0.995 0.000
M86.87 Other osteomyelitis (Ankle and foot)
0.005 0.995 0.000
B34.9 Viral infection, unspecified
0.005 0.995 0.000
C67 Malignant neoplasm of bladder
0.000 0.995 0.005
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.005 0.995 0.000
C67.4 Posterior wall of bladder
0.000 0.995 0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.995 0.004
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.995 0.004
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.995 0.004
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.995 0.004
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.995 0.004
T44.0 Anticholinesterase agents
0.000 0.995 0.004
M86.17 Other acute osteomyelitis (Ankle and foot)
0.004 0.995 0.000
M86.86 Other osteomyelitis (Lower leg)
0.004 0.995 0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)
0.004 0.995 0.000
M86.89 Other osteomyelitis (Site unspecified)
0.004 0.995 0.000
M86.88 Other osteomyelitis (Other)
0.004 0.995 0.000
M86.84 Other osteomyelitis (Hand)
0.004 0.995 0.000
M86.83 Other osteomyelitis (Forearm)
0.004 0.995 0.000
M86.82 Other osteomyelitis (Upper arm)
0.004 0.995 0.000
M86.81 Other osteomyelitis (Shoulder region)
0.004 0.995 0.000
M86.80 Other osteomyelitis (Multiple sites)
0.004 0.995 0.000
M86.64 Other chronic osteomyelitis (Hand)
0.004 0.995 0.000
M86.63 Other chronic osteomyelitis (Forearm)
0.004 0.995 0.000
M86.62 Other chronic osteomyelitis (Upper arm)
0.004 0.995 0.000
M86.61 Other chronic osteomyelitis (Shoulder region)
0.004 0.995 0.000
M86.60 Other chronic osteomyelitis (Multiple sites)
0.004 0.995 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.995 0.004
M86.69 Other chronic osteomyelitis (Site unspecified)
0.004 0.995 0.000
L43.8 Other lichen planus
0.005 0.995 0.000
M86.19 Other acute osteomyelitis (Site unspecified)
0.004 0.995 0.000
M86.18 Other acute osteomyelitis (Other)
0.004 0.995 0.000
M86.16 Other acute osteomyelitis (Lower leg)
0.004 0.995 0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)
0.004 0.995 0.000
M86.14 Other acute osteomyelitis (Hand)
0.004 0.995 0.000
M86.13 Other acute osteomyelitis (Forearm)
0.004 0.995 0.000
M86.12 Other acute osteomyelitis (Upper arm)
0.004 0.995 0.000
M86.11 Other acute osteomyelitis (Shoulder region)
0.004 0.995 0.000
M86.10 Other acute osteomyelitis (Multiple sites)
0.004 0.995 0.000
C67.8 Overlapping lesion of bladder
0.000 0.995 0.004
E66 Obesity
0.000 0.995 0.005
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.004 0.996 0.000
M86.08 Acute haematogenous osteomyelitis (Other)
0.004 0.996 0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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