TreeWAS – Variant ID: rs1656402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H52.1 Myopia	0.374	0.626	0.000
H52 Disorders of refraction and accommodation	0.186	0.814	0.000
H52.3 Anisometropia and aniseikonia	0.162	0.838	0.000
H52.7 Disorder of refraction, unspecified	0.141	0.859	0.000
H52.6 Other disorders of refraction	0.134	0.866	0.000
H52.5 Disorders of accommodation	0.134	0.866	0.000
H52.4 Presbyopia	0.134	0.866	0.000
H52.0 Hypermetropia	0.133	0.866	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.062	0.938	0.000
H51 Other disorders of binocular movement	0.051	0.949	0.000
H49 Paralytic strabismus	0.049	0.951	0.000
H52.2 Astigmatism	0.043	0.957	0.001
H51.2 Internuclear ophthalmoplegia	0.043	0.957	0.000
H49.1 Fourth [trochlear] nerve palsy	0.041	0.959	0.000
H49.9 Paralytic strabismus, unspecified	0.038	0.962	0.000
H51.9 Disorder of binocular movement, unspecified	0.037	0.963	0.000
H51.8 Other specified disorders of binocular movement	0.037	0.963	0.000
H51.1 Convergence insufficiency and excess	0.037	0.963	0.000
H51.0 Palsy of conjugate gaze	0.037	0.963	0.000
H49.2 Sixth [abducent] nerve palsy	0.036	0.963	0.000
H49.8 Other paralytic strabismus	0.035	0.965	0.000
H49.4 Progressive external ophthalmoplegia	0.035	0.965	0.000
H49.3 Total (external) ophthalmoplegia	0.035	0.965	0.000
H49.0 Third [oculomotor] nerve palsy	0.027	0.973	0.000
Y45.1 Salicylates	0.020	0.980	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.020	0.980	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.020	0.980	0.000
Y45.8 Other analgesics and antipyretics	0.019	0.981	0.000
I35.0 Aortic (valve) stenosis	0.000	0.984	0.016
Y45.0 Opioids and related analgesics	0.016	0.984	0.000
Y45.2 Propionic acid derivatives	0.015	0.985	0.000
Y45.5 4-Aminophenol derivatives	0.015	0.985	0.000
Y45.4 Antirheumatics	0.014	0.985	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.014	0.986	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.014	0.986	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.987	0.013
G40 Epilepsy	0.012	0.988	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.012	0.988	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.988	0.012
I35.8 Other aortic valve disorders	0.000	0.989	0.011
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.011	0.989	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.989	0.011
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.989	0.011
G40.8 Other epilepsy	0.010	0.990	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.990	0.010
G40.5 Special epileptic syndromes	0.010	0.990	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.010	0.990	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.009	0.991	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.009	0.991	0.000
M35.3 Polymyalgia rheumatica	0.000	0.991	0.009
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.991	0.009
Z90.3 Acquired absence of part of stomach	0.000	0.991	0.009
I35.1 Aortic (valve) insufficiency	0.000	0.992	0.008
C80.9 Malignant neoplasm, unspecified	0.008	0.992	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.008	0.992	0.000
Z99.8 Dependence on other enabling machines and devices	0.007	0.993	0.000
H50 Other strabismus	0.007	0.993	0.001
H50.0 Convergent concomitant strabismus	0.005	0.994	0.000
H50.6 Mechanical strabismus	0.005	0.995	0.001
H50.3 Intermittent heterotropia	0.005	0.995	0.001
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.005	0.995	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.995	0.005
H46 Optic neuritis	0.005	0.995	0.000
H50.8 Other specified strabismus	0.005	0.995	0.001
H50.5 Heterophoria	0.004	0.995	0.001
H50.4 Other and unspecified heterotropia	0.004	0.995	0.001
K91.3 Postoperative intestinal obstruction	0.005	0.995	0.000
C80 Malignant neoplasm without specification of site	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
H50.2 Vertical strabismus	0.003	0.996	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.996	0.004
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.996	0.004
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.996	0.004
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.996	0.004
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.996	0.004
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.004	0.996	0.000
H61.0 Perichondritis of external ear	0.004	0.996	0.000
H47.1 Papilloedema, unspecified	0.004	0.996	0.000
M35 Other systemic involvement of connective tissue	0.000	0.996	0.004
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.003	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
R90.0 Intracranial space-occupying lesion	0.003	0.997	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
Chapter VII Diseases of the eye and adnexa	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
Z73.3 Stress, not elsewhere classified	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
O16 Unspecified maternal hypertension	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
H11.0 Pterygium	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.997	0.003
M35.8 Other specified systemic involvement of connective tissue	0.000	0.997	0.003
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.997	0.003
M35.5 Multifocal fibrosclerosis	0.000	0.997	0.003
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.997	0.003
M35.2 Behcet's disease	0.000	0.997	0.003
M35.7 Hypermobility syndrome	0.000	0.997	0.003
H11.2 Conjunctival scars	0.003	0.997	0.000
H59.0 Vitreous syndrome following cataract surgery	0.003	0.997	0.000
J38.3 Other diseases of vocal cords	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
J81 Pulmonary oedema	0.000	0.997	0.003
H11.4 Other conjunctival vascular disorders and cysts	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
G70.0 Myasthenia gravis	0.000	0.997	0.003
H47.3 Other disorders of optic disk	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.997	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.997	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.997	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.000	0.997	0.003
M70.46 Prepatellar bursitis-Lower Leg	0.003	0.997	0.000
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.000	0.997	0.002
A08.4 Viral intestinal infection, unspecified	0.000	0.997	0.003
H11.9 Disorder of conjunctiva, unspecified	0.003	0.997	0.000
H11.1 Conjunctival degenerations and deposits	0.002	0.997	0.000
D12.2 Ascending colon	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.997	0.002
M35.1 Other overlap syndromes	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.000	0.998	0.002
Z94.1 Heart transplant status	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
G40.9 Epilepsy, unspecified	0.002	0.998	0.000
M21.2 Flexion deformity	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
H13 Disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.002	0.998	0.001
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
R79.9 Abnormal finding of blood chemistry, unspecified	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
S01.3 Open wound of ear	0.000	0.998	0.002
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
H40-H42 Glaucoma	0.001	0.998	0.001
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
M21.4 Flat foot [pes planus] (acquired)	0.000	0.998	0.002
M21.7 Unequal limb length (acquired)	0.000	0.998	0.002
J38.4 Oedema of larynx	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.998	0.002
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.001	0.998	0.001
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.998	0.002
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.998	0.002
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.998	0.002
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.998	0.002
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.998	0.002
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.998	0.002
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.998	0.002
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.998	0.002
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.998	0.002
H13.3 Ocular pemphigoid	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
H40 Glaucoma	0.000	0.998	0.002
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.998	0.002
H25.1 Senile nuclear cataract	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y84.0 Cardiac catheterisation	0.000	0.998	0.002
H42 Glaucoma in diseases classified elsewhere	0.001	0.998	0.001
H43-H45 Disorders of vitreous body and globe	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.002
H40.0 Glaucoma suspect	0.000	0.998	0.002
M21.8 Other specified acquired deformities of limbs	0.000	0.998	0.002
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.998	0.002
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.998	0.002
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.998	0.002
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.998	0.002
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.998	0.002
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.998	0.002
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.998	0.002
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.998	0.002
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.998	0.002
J38.7 Other diseases of larynx	0.002	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.998	0.002
X10.0 Home	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.998	0.002
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z94 Transplanted organ and tissue status	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.998	0.002
M21.78 Unequal limb length (acquired)-Other	0.000	0.998	0.002
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.998	0.002
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.998	0.002
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.998	0.002
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.998	0.002
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.001	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
Z94.4 Liver transplant status	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.998	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.998	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.998	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.998	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.998	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.998	0.002
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
H10 Conjunctivitis	0.002	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.001
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.001
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.001
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.998	0.001
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.001
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.001
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.001
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.001
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.998	0.001
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.001
H16.0 Corneal ulcer	0.002	0.998	0.000
H40.4 Glaucoma secondary to eye inflammation	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.998	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
R86.8 Other abnormal findings	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
Z30.8 Other contraceptive management	0.002	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.001	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.001	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.001	0.998	0.000
Z73.1 Accentuation of personality traits	0.001	0.998	0.000
Z73.0 Burn-out	0.001	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.000	0.998	0.002
H40.3 Glaucoma secondary to eye trauma	0.000	0.998	0.002
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
N75.0 Cyst of Bartholin's gland	0.000	0.998	0.002
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.998	0.000
L60.2 Onychogryphosis	0.002	0.998	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.998	0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
Z94.5 Skin transplant status	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.001
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
H42.8 Glaucoma in other diseases classified elsewhere	0.001	0.998	0.001
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.001	0.998	0.001
S06.8 Other intracranial injuries	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.001	0.998	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.001	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.998	0.001
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.998	0.001
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.998	0.001
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.998	0.001
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.998	0.001
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.998	0.001
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.998	0.001
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.998	0.001
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.001
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.001
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.001
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
G70.8 Other specified myoneural disorders	0.000	0.998	0.001
G70.2 Congenital and developmental myasthenia	0.000	0.998	0.001
G70.1 Toxic myoneural disorders	0.000	0.998	0.001
O42 Premature rupture of membranes	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.001
H18.0 Corneal pigmentations and deposits	0.001	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.001	0.998	0.000
Z94.6 Bone transplant status	0.001	0.998	0.000
Z94.3 Heart and lungs transplant status	0.001	0.998	0.000
H25-H28 Disorders of lens	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.001
C75.9 Endocrine gland, unspecified	0.001	0.998	0.000
H10.8 Other conjunctivitis	0.001	0.998	0.000
H10.5 Blepharoconjunctivitis	0.001	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.001	0.998	0.000
H10.2 Other acute conjunctivitis	0.001	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.001	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.001	0.998	0.000
H21.4 Pupillary membranes	0.001	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.001
H16.3 Interstitial and deep keratitis	0.001	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.998	0.000
H16.9 Keratitis, unspecified	0.001	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.001	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.999	0.001
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.999	0.001
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.999	0.001
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.999	0.001
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.999	0.001
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.999	0.001
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.999	0.001
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.999	0.001
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.999	0.001
T45.2 Vitamins, not elsewhere classified	0.001	0.999	0.000
Z01.7 Laboratory examination	0.000	0.999	0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.999	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.999	0.001
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
H61.3 Acquired stenosis of external ear canal	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.999	0.000
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.999	0.001
Z94.2 Lung transplant status	0.001	0.999	0.000
H43 Disorders of vitreous body	0.001	0.999	0.000
M23.5 Chronic instability of knee	0.001	0.999	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
Z52.4 Kidney donor	0.000	0.999	0.001
H57 Other disorders of eye and adnexa	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.001	0.999	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.001	0.999	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.001	0.999	0.000
K91.5 Postcholecystectomy syndrome	0.001	0.999	0.000
O12.1 Gestational proteinuria	0.001	0.999	0.000
T50.8 Diagnostic agents	0.001	0.999	0.000
H61 Other disorders of external ear	0.001	0.999	0.000
H16.8 Other keratitis	0.001	0.999	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.001	0.999	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.999	0.000
D75.1 Secondary polycythaemia	0.000	0.999	0.001
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
M70.4 Prepatellar bursitis	0.001	0.999	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
H18 Other disorders of cornea	0.001	0.999	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
H10.4 Chronic conjunctivitis	0.001	0.999	0.000
H43.8 Other disorders of vitreous body	0.001	0.999	0.000
Z73.8 Other problems related to life-management difficulty	0.001	0.999	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.999	0.001
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
R22.2 Localised swelling, mass and lump, trunk	0.001	0.999	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.001	0.999	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.4 Other laxatives	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
T47.2 Stimulant laxatives	0.001	0.999	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.999	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
T50.5 Appetite depressants	0.001	0.999	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.999	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.999	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.999	0.000
H27 Other disorders of lens	0.001	0.999	0.000
G83.4 Cauda equina syndrome	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
H40.1 Primary open-angle glaucoma	0.000	0.999	0.001
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
R86.7 Abnormal histological findings	0.001	0.999	0.000
T49.9 Topical agent, unspecified	0.001	0.999	0.000
T49.8 Other topical agents	0.001	0.999	0.000
T49.7 Dental drugs, topically applied	0.001	0.999	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.999	0.000
T49.2 Local astringents and local detergents	0.001	0.999	0.000
T49.1 Antipruritics	0.001	0.999	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M23.57 Chronic instability of knee (Capsular ligament)	0.001	0.999	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.001	0.999	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.001	0.999	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations