TreeWAS – Variant ID: rs1665650

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.000	0.775	0.225
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.775	0.225
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.793	0.207
E20-E35 Disorders of other endocrine glands	0.000	0.801	0.199
E21.2 Other hyperparathyroidism	0.000	0.805	0.195
E21.3 Hyperparathyroidism, unspecified	0.000	0.810	0.190
E27 Other disorders of adrenal gland	0.000	0.815	0.185
E27.1 Primary adrenocortical insufficiency	0.000	0.825	0.175
E25 Adrenogenital disorders	0.000	0.828	0.172
E24 Cushing's syndrome	0.000	0.833	0.167
E27.2 Addisonian crisis	0.000	0.838	0.162
E26 Hyperaldosteronism	0.000	0.838	0.162
E31 Polyglandular dysfunction	0.000	0.840	0.160
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.842	0.158
E28 Ovarian dysfunction	0.000	0.843	0.157
E21.4 Other specified disorders of parathyroid gland	0.000	0.844	0.156
E34 Other endocrine disorders	0.000	0.847	0.153
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.847	0.153
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.857	0.143
E30 Disorders of puberty, not elsewhere classified	0.000	0.857	0.143
E29 Testicular dysfunction	0.000	0.858	0.142
E32 Diseases of thymus	0.000	0.859	0.141
E24.9 Cushing's syndrome, unspecified	0.000	0.862	0.138
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.863	0.137
E26.9 Hyperaldosteronism, unspecified	0.000	0.866	0.134
E27.5 Adrenomedullary hyperfunction	0.000	0.867	0.133
E27.0 Other adrenocortical overactivity	0.000	0.867	0.133
E31.0 Autoimmune polyglandular failure	0.000	0.867	0.133
E24.8 Other Cushing's syndrome	0.000	0.868	0.132
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.872	0.128
E24.0 Pituitary-dependent Cushing's disease	0.000	0.872	0.128
E28.2 Polycystic ovarian syndrome	0.000	0.873	0.127
E20 Hypoparathyroidism	0.000	0.874	0.126
E25.9 Adrenogenital disorder, unspecified	0.000	0.877	0.123
E25.8 Other adrenogenital disorders	0.000	0.877	0.123
E26.0 Primary hyperaldosteronism	0.000	0.879	0.121
E34.9 Endocrine disorder, unspecified	0.000	0.880	0.120
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.880	0.120
E24.3 Ectopic ACTH syndrome	0.000	0.880	0.120
E24.1 Nelson's syndrome	0.000	0.880	0.120
E34.8 Other specified endocrine disorders	0.000	0.881	0.119
E26.8 Other hyperaldosteronism	0.000	0.883	0.116
E26.1 Secondary hyperaldosteronism	0.000	0.883	0.116
E27.8 Other specified disorders of adrenal gland	0.000	0.884	0.116
E31.9 Polyglandular dysfunction, unspecified	0.000	0.885	0.115
E31.8 Other polyglandular dysfunction	0.000	0.885	0.115
E31.1 Polyglandular hyperfunction	0.000	0.885	0.115
E34.3 Short stature, not elsewhere classified	0.000	0.887	0.113
E28.9 Ovarian dysfunction, unspecified	0.000	0.887	0.113
E28.8 Other ovarian dysfunction	0.000	0.887	0.113
E28.1 Androgen excess	0.000	0.887	0.113
E28.0 Oestrogen excess	0.000	0.887	0.113
E28.3 Primary ovarian failure	0.000	0.888	0.112
E34.5 Androgen resistance syndrome	0.000	0.890	0.110
E34.4 Constitutional tall stature	0.000	0.890	0.110
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.890	0.110
E34.1 Other hypersecretion of intestinal hormones	0.000	0.890	0.110
E29.1 Testicular hypofunction	0.000	0.892	0.108
E24.2 Drug-induced Cushing's syndrome	0.000	0.892	0.108
E27.9 Disorder of adrenal gland, unspecified	0.000	0.894	0.106
E30.9 Disorder of puberty, unspecified	0.000	0.897	0.102
E30.8 Other disorders of puberty	0.000	0.897	0.102
E30.1 Precocious puberty	0.000	0.897	0.102
E30.0 Delayed puberty	0.000	0.897	0.102
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.897	0.102
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.897	0.102
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.897	0.102
E29.8 Other testicular dysfunction	0.000	0.898	0.102
E29.0 Testicular hyperfunction	0.000	0.898	0.102
E32.9 Disease of thymus, unspecified	0.000	0.899	0.101
E32.1 Abscess of thymus	0.000	0.899	0.101
E32.0 Persistent hyperplasia of thymus	0.000	0.899	0.101
E32.8 Other diseases of thymus	0.000	0.901	0.099
E29.9 Testicular dysfunction, unspecified	0.000	0.905	0.095
E34.0 Carcinoid syndrome	0.000	0.906	0.094
E23 Hypofunction and other disorders of pituitary gland	0.000	0.908	0.092
E20.8 Other hypoparathyroidism	0.000	0.909	0.090
E20.0 Idiopathic hypoparathyroidism	0.000	0.909	0.090
E22 Hyperfunction of pituitary gland	0.000	0.915	0.085
E20.9 Hypoparathyroidism, unspecified	0.000	0.916	0.084
E20.1 Pseudohypoparathyroidism	0.000	0.919	0.081
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.934	0.066
E23.1 Drug-induced hypopituitarism	0.000	0.934	0.066
E23.6 Other disorders of pituitary gland	0.000	0.935	0.065
E22.8 Other hyperfunction of pituitary gland	0.000	0.939	0.061
E23.2 Diabetes insipidus	0.000	0.939	0.061
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.939	0.061
E23.7 Disorder of pituitary gland, unspecified	0.000	0.941	0.059
E22.0 Acromegaly and pituitary gigantism	0.000	0.945	0.055
E22.1 Hyperprolactinaemia	0.000	0.947	0.053
E23.0 Hypopituitarism	0.000	0.955	0.045
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.963	0.037
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.984	0.016
N32.8 Other specified disorders of bladder	0.000	0.987	0.013
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.988	0.012
S80.8 Other superficial injuries of lower leg	0.000	0.989	0.011
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.989	0.011
F31.9 Bipolar affective disorder, unspecified	0.000	0.989	0.011
S80 Superficial injury of lower leg	0.000	0.989	0.011
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.990	0.010
M87.9 Osteonecrosis, unspecified	0.000	0.991	0.009
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.991	0.009
M65.34 Trigger finger-Hand	0.000	0.991	0.009
S81.8 Open wound of other parts of lower leg	0.000	0.991	0.009
M87 Osteonecrosis	0.000	0.991	0.009
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.991	0.009
S80.9 Superficial injury of lower leg, unspecified	0.000	0.991	0.009
S80.7 Multiple superficial injuries of lower leg	0.000	0.992	0.008
S80-S89 Injuries to the knee and lower leg	0.000	0.992	0.008
S80.0 Contusion of knee	0.000	0.992	0.008
M87.2 Osteonecrosis due to previous trauma	0.000	0.992	0.008
S81 Open wound of lower leg	0.000	0.992	0.008
M87.8 Other osteonecrosis	0.000	0.992	0.008
S83.3 Tear of articular cartilage of knee, current	0.000	0.992	0.008
S83.1 Dislocation of knee	0.000	0.992	0.007
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.993	0.007
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.993	0.007
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.993	0.007
S83.0 Dislocation of patella	0.000	0.993	0.007
F25.9 Schizoaffective disorder, unspecified	0.007	0.993	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.007	0.993	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.993	0.007
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.993	0.007
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.993	0.007
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.993	0.007
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.993	0.007
I26 Pulmonary embolism	0.000	0.993	0.007
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.993	0.007
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.993	0.007
M87.3 Other secondary osteonecrosis	0.000	0.993	0.007
F25 Schizoaffective disorders	0.007	0.993	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.993	0.007
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.993	0.006
I84.8 Unspecified haemorrhoids with other complications	0.000	0.993	0.007
M87.1 Osteonecrosis due to drugs	0.000	0.993	0.006
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.993	0.006
Z42.0 Follow-up care involving plastic surgery of head and neck	0.006	0.994	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.994	0.006
F25.1 Schizoaffective disorder, depressive type	0.006	0.994	0.000
S85 Injury of blood vessels at lower leg level	0.000	0.994	0.006
M86-M90 Other osteopathies	0.000	0.994	0.006
F25.0 Schizoaffective disorder, manic type	0.006	0.994	0.000
S88 Traumatic amputation of lower leg	0.000	0.994	0.006
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.994	0.006
S83.7 Injury to multiple structures of knee	0.000	0.994	0.006
S87 Crushing injury of lower leg	0.000	0.994	0.006
S84 Injury of nerves at lower leg level	0.000	0.994	0.006
M89 Other disorders of bone	0.000	0.994	0.006
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.994	0.006
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.994	0.006
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.994	0.006
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.994	0.006
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.994	0.006
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.994	0.006
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.994	0.006
M89.0 Algoneurodystrophy	0.000	0.994	0.006
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.994	0.006
M87.88 Other osteonecrosis (Other)	0.000	0.994	0.006
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.994	0.006
M87.84 Other osteonecrosis (Hand)	0.000	0.994	0.006
M87.83 Other osteonecrosis (Forearm)	0.000	0.994	0.006
M87.82 Other osteonecrosis (Upper arm)	0.000	0.994	0.006
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.994	0.006
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.994	0.006
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.994	0.006
S86 Injury of muscle and tendon at lower leg level	0.000	0.994	0.006
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.994	0.006
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.994	0.006
C91.1 Chronic lymphocytic leukaemia	0.000	0.994	0.006
M89.9 Disorder of bone, unspecified	0.000	0.994	0.006
M86 Osteomyelitis	0.000	0.994	0.006
M89.03 Algoneurodystrophy (Forearm)	0.000	0.995	0.005
M87.86 Other osteonecrosis (Lower leg)	0.000	0.995	0.005
C45.0 Mesothelioma of pleura	0.000	0.995	0.005
F25.2 Schizoaffective disorder, mixed type	0.005	0.995	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.000	0.995	0.005
N32.3 Diverticulum of bladder	0.000	0.995	0.005
M86.6 Other chronic osteomyelitis	0.000	0.995	0.005
M87.39 Other secondary osteonecrosis (Site unspecified)	0.000	0.995	0.005
M87.38 Other secondary osteonecrosis (Other)	0.000	0.995	0.005
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.000	0.995	0.005
M87.36 Other secondary osteonecrosis (Lower leg)	0.000	0.995	0.005
M87.34 Other secondary osteonecrosis (Hand)	0.000	0.995	0.005
M87.33 Other secondary osteonecrosis (Forearm)	0.000	0.995	0.005
M87.32 Other secondary osteonecrosis (Upper arm)	0.000	0.995	0.005
M87.31 Other secondary osteonecrosis (Shoulder region)	0.000	0.995	0.005
M87.30 Other secondary osteonecrosis (Multiple sites)	0.000	0.995	0.005
S81.0 Open wound of knee	0.000	0.995	0.005
F25.8 Other schizoaffective disorders	0.005	0.995	0.000
N32 Other disorders of bladder	0.000	0.995	0.005
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.000	0.995	0.005
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.000	0.995	0.005
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.000	0.995	0.005
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.000	0.995	0.005
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.000	0.995	0.005
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.000	0.995	0.005
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.000	0.995	0.005
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.000	0.995	0.005
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.000	0.995	0.005
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.000	0.995	0.005
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.000	0.995	0.005
M87.18 Osteonecrosis due to drugs (Other)	0.000	0.995	0.005
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.000	0.995	0.005
M87.16 Osteonecrosis due to drugs (Lower leg)	0.000	0.995	0.005
M87.14 Osteonecrosis due to drugs (Hand)	0.000	0.995	0.005
M87.13 Osteonecrosis due to drugs (Forearm)	0.000	0.995	0.005
M87.12 Osteonecrosis due to drugs (Upper arm)	0.000	0.995	0.005
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.000	0.995	0.005
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.000	0.995	0.005
M86.9 Osteomyelitis, unspecified	0.000	0.995	0.005
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.995	0.005
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.000	0.995	0.005
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.995	0.005
S89 Other and unspecified injuries of lower leg	0.000	0.995	0.005
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.995	0.005
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.995	0.005
C91.9 Lymphoid leukaemia, unspecified	0.000	0.995	0.005
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.995	0.005
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.995	0.005
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.995	0.005
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.995	0.005
S85.8 Injury of other blood vessels at lower leg level	0.000	0.995	0.005
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.995	0.005
S85.5 Injury of popliteal vein	0.000	0.995	0.005
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.995	0.005
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.995	0.005
S85.2 Injury of peroneal artery	0.000	0.995	0.005
S85.0 Injury of popliteal artery	0.000	0.995	0.005
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.995	0.005
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.995	0.004
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.995	0.004
S88.0 Traumatic amputation at knee level	0.000	0.995	0.004
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.995	0.005
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.995	0.005
C91 Lymphoid leukaemia	0.000	0.995	0.005
M89.6 Osteopathy after poliomyelitis	0.000	0.995	0.004
M89.2 Other disorders of bone development and growth	0.000	0.995	0.004
M89.1 Epiphyseal arrest	0.000	0.995	0.004
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.995	0.004
S84.8 Injury of other nerves at lower leg level	0.000	0.995	0.004
S84.7 Injury of multiple nerves at lower leg level	0.000	0.995	0.004
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.995	0.004
S84.0 Injury of tibial nerve at lower leg level	0.000	0.995	0.004
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.995	0.004
S87.0 Crushing injury of knee	0.000	0.995	0.004
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
M86.66 Other chronic osteomyelitis (Lower leg)	0.000	0.995	0.004
M89.04 Algoneurodystrophy (Hand)	0.000	0.995	0.004
M89.08 Algoneurodystrophy (Other)	0.000	0.995	0.004
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.995	0.004
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.995	0.004
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.995	0.004
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.000	0.995	0.004
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.995	0.004
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.996	0.004
M90 Osteopathies in diseases classified elsewhere	0.000	0.996	0.004
S86.0 Injury of Achilles tendon	0.000	0.996	0.004
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.996	0.004
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.996	0.004
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.996	0.004
M86.3 Chronic multifocal osteomyelitis	0.000	0.996	0.004
M86.2 Subacute osteomyelitis	0.000	0.996	0.004
M86.0 Acute haematogenous osteomyelitis	0.000	0.996	0.004
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.996	0.004
M65.3 Trigger finger	0.000	0.996	0.004
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.996	0.004
M89.5 Osteolysis	0.000	0.996	0.004
M86.69 Other chronic osteomyelitis (Site unspecified)	0.000	0.996	0.004
C45 Mesothelioma	0.000	0.996	0.004
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.996	0.004
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.996	0.004
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.996	0.004
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.996	0.004
N32.4 Rupture of bladder, nontraumatic	0.000	0.996	0.004
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.996	0.004
N32.9 Bladder disorder, unspecified	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.000	0.996	0.004
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
M86.1 Other acute osteomyelitis	0.000	0.996	0.004
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.996	0.004
C91.0 Acute lymphoblastic leukaemia	0.000	0.996	0.004
M86.64 Other chronic osteomyelitis (Hand)	0.000	0.996	0.004
M86.63 Other chronic osteomyelitis (Forearm)	0.000	0.996	0.004
M86.62 Other chronic osteomyelitis (Upper arm)	0.000	0.996	0.004
M86.61 Other chronic osteomyelitis (Shoulder region)	0.000	0.996	0.004
M86.60 Other chronic osteomyelitis (Multiple sites)	0.000	0.996	0.004
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.996	0.004
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.996	0.004
M86.68 Other chronic osteomyelitis (Other)	0.000	0.996	0.004
C92.0 Acute myeloid leukaemia	0.000	0.996	0.004
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.996	0.004
M86.8 Other osteomyelitis	0.000	0.996	0.004
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.996	0.004
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.996	0.004
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.996	0.004
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.996	0.004
M89.3 Hypertrophy of bone	0.000	0.996	0.004
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.996	0.004
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.996	0.004
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.996	0.004
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.996	0.004
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.996	0.004
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.996	0.004
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.996	0.004
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.996	0.004
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
S89.7 Multiple injuries of lower leg	0.000	0.996	0.004
S89.1 Other specified injuries of lower leg	0.000	0.996	0.004
S89.0 Multiple injuries of lower leg	0.000	0.996	0.004
S83.2 Tear of meniscus, current	0.000	0.996	0.004
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.996	0.004
M88 Paget's disease of bone [osteitis deformans]	0.000	0.996	0.004
C45.7 Mesothelioma of other sites	0.000	0.996	0.004
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.996	0.003
C91.7 Other lymphoid leukaemia	0.000	0.996	0.003
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.996	0.003
C91.3 Prolymphocytic leukaemia	0.000	0.996	0.003
C91.2 Subacute lymphocytic leukaemia	0.000	0.996	0.003
M90.7 Fracture of bone in neoplastic disease	0.000	0.996	0.004
M89.98 Disorder of bone, unspecified (Other)	0.000	0.996	0.003
C91.5 Adult T-cell leukaemia	0.000	0.996	0.003
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.996	0.003
M89.18 Epiphyseal arrest (Other)	0.000	0.996	0.003
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.996	0.003
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.996	0.003
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.996	0.003
M89.14 Epiphyseal arrest (Hand)	0.000	0.996	0.003
M89.13 Epiphyseal arrest (Forearm)	0.000	0.996	0.003
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.996	0.003
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.996	0.003
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.996	0.003
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.996	0.003
M89.28 Other disorders of bone development and growth (Other)	0.000	0.996	0.003
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.996	0.003
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.996	0.003
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.996	0.003
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.996	0.003
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.996	0.003
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.996	0.003
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.996	0.003
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.996	0.003
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.996	0.003
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.996	0.003
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.996	0.003
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.996	0.003
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.996	0.003
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.996	0.003
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.996	0.003
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.996	0.003
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.996	0.003
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.996	0.003
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.996	0.003
S89.9 Unspecified injury of lower leg	0.000	0.996	0.003
C92 Myeloid leukaemia	0.000	0.996	0.004
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.996	0.003
N32.2 Vesical fistula, not elsewhere classified	0.000	0.996	0.003
Z49.1 Extracorporeal dialysis	0.000	0.996	0.004
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
M90.5 Osteonecrosis in other diseases classified elsewhere	0.000	0.997	0.003
M90.4 Osteonecrosis due to heamoglobinopathy	0.000	0.997	0.003
M90.3 Osteonecrosis in caisson disease	0.000	0.997	0.003
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.000	0.997	0.003
M90.0 Tuberculosis of bone	0.000	0.997	0.003
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.997	0.003
S86.00 Unspecified injury of Achilles tendon	0.000	0.997	0.003
M90.8 Osteopathy in other diseases classified elsewhere	0.000	0.997	0.003
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.003
N32.1 Vesicointestinal fistula	0.000	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.997	0.003
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.08 Acute haematogenous osteomyelitis (Other)	0.000	0.997	0.003
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.000	0.997	0.003
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.000	0.997	0.003
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.04 Acute haematogenous osteomyelitis (Hand)	0.000	0.997	0.003
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.000	0.997	0.003
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.000	0.997	0.003
M86.29 Subacute osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.28 Subacute osteomyelitis (Other)	0.000	0.997	0.003
M86.27 Subacute osteomyelitis (Ankle and foot)	0.000	0.997	0.003
M86.26 Subacute osteomyelitis (Lower leg)	0.000	0.997	0.003
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.24 Subacute osteomyelitis (Hand)	0.000	0.997	0.003
M86.23 Subacute osteomyelitis (Forearm)	0.000	0.997	0.003
M86.22 Subacute osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.21 Subacute osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.20 Subacute osteomyelitis (Multiple sites)	0.000	0.997	0.003
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.38 Chronic multifocal osteomyelitis (Other)	0.000	0.997	0.003
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.000	0.997	0.003
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.000	0.997	0.003
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.34 Chronic multifocal osteomyelitis (Hand)	0.000	0.997	0.003
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.000	0.997	0.003
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.000	0.997	0.003
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.000	0.997	0.003
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.000	0.997	0.003
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.000	0.997	0.003
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.000	0.997	0.003
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.000	0.997	0.003
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.000	0.997	0.003
M25.46 Effusion of joint (Lower leg)	0.000	0.997	0.003
C92.1 Chronic myeloid leukaemia	0.000	0.997	0.003
M65.38 Trigger finger-Other	0.000	0.997	0.003
M65.37 Trigger finger-Ankle/foot	0.000	0.997	0.003
M65.36 Trigger finger-Lower leg	0.000	0.997	0.003
M65.35 Trigger finger-Pelvic/thigh	0.000	0.997	0.003
M65.33 Trigger finger-Forearm	0.000	0.997	0.003
M65.32 Trigger finger-Upper arm	0.000	0.997	0.003
M65.31 Trigger finger-Shldr region	0.000	0.997	0.003
M65.30 Trigger finger-Mult sites	0.000	0.997	0.003
M90.1 Periostitis in other infectious diseases classified elsewhere	0.000	0.997	0.003
M89.59 Osteolysis (Site unspecified)	0.000	0.997	0.003
M89.58 Osteolysis (Other)	0.000	0.997	0.003
M89.57 Osteolysis (Ankle and foot)	0.000	0.997	0.003
M89.54 Osteolysis (Hand)	0.000	0.997	0.003
M89.53 Osteolysis (Forearm)	0.000	0.997	0.003
M89.52 Osteolysis (Upper arm)	0.000	0.997	0.003
M89.51 Osteolysis (Shoulder region)	0.000	0.997	0.003
M89.50 Osteolysis (Multiple sites)	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
M90.6 Osteitis deformans in neoplastic disease	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
M86.19 Other acute osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.18 Other acute osteomyelitis (Other)	0.000	0.997	0.003
M86.16 Other acute osteomyelitis (Lower leg)	0.000	0.997	0.003
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.14 Other acute osteomyelitis (Hand)	0.000	0.997	0.003
M86.13 Other acute osteomyelitis (Forearm)	0.000	0.997	0.003
M86.12 Other acute osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.11 Other acute osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.10 Other acute osteomyelitis (Multiple sites)	0.000	0.997	0.003
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.997	0.003
C92.7 Other myeloid leukaemia	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.000	0.997	0.003
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.000	0.997	0.003
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.000	0.997	0.003
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.000	0.997	0.003
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.000	0.997	0.003
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.000	0.997	0.003
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.000	0.997	0.003
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.000	0.997	0.003
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.997	0.003
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
M89.56 Osteolysis (Lower leg)	0.000	0.997	0.003
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.997	0.003
F20.9 Schizophrenia, unspecified	0.003	0.997	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.88 Other osteomyelitis (Other)	0.000	0.997	0.003
M86.84 Other osteomyelitis (Hand)	0.000	0.997	0.003
M86.83 Other osteomyelitis (Forearm)	0.000	0.997	0.003
M86.82 Other osteomyelitis (Upper arm)	0.000	0.997	0.003
M86.81 Other osteomyelitis (Shoulder region)	0.000	0.997	0.003
M86.80 Other osteomyelitis (Multiple sites)	0.000	0.997	0.003
F20 Schizophrenia	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.997	0.003
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.997	0.003
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.997	0.003
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.997	0.003
M89.34 Hypertrophy of bone (Hand)	0.000	0.997	0.003
M89.33 Hypertrophy of bone (Forearm)	0.000	0.997	0.003
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.997	0.003
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.997	0.003
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.997	0.003
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.997	0.003
M88.8 Paget's disease of other bones	0.000	0.997	0.003
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
M86.17 Other acute osteomyelitis (Ankle and foot)	0.000	0.997	0.003
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.997	0.000
M65.39 Trigger finger-Site unspec	0.000	0.997	0.003
E40-E46 Malnutrition	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.997	0.003
M88.0 Paget's disease of skull	0.000	0.997	0.003
S89.8 Other specified injuries of lower leg	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.997	0.003
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations