TreeWAS – Variant ID: rs16850360

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M31.6 Other giant cell arteritis	0.013	0.987	0.000
M31 Other necrotising vasculopathies	0.011	0.989	0.000
N84.1 Polyp of cervix uteri	0.000	0.989	0.011
M31.3 Wegener's granulomatosis	0.010	0.990	0.000
K82.8 Other specified diseases of gallbladder	0.009	0.991	0.000
Z96.0 Presence of urogenital implants	0.008	0.992	0.000
N84 Polyp of female genital tract	0.000	0.992	0.008
N84.0 Polyp of corpus uteri	0.000	0.992	0.008
M31.9 Necrotising vasculopathy, unspecified	0.008	0.992	0.000
M31.8 Other specified necrotising vasculopathies	0.008	0.992	0.000
M31.7 Microscopic polyangiitis	0.008	0.992	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.008	0.992	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.008	0.992	0.000
M31.2 Lethal midline granuloma	0.008	0.992	0.000
M31.1 Thrombotic microangiopathy	0.008	0.992	0.000
M31.0 Hypersensitivity angiitis	0.008	0.992	0.000
K82 Other diseases of gallbladder	0.008	0.992	0.000
L40.5 Arthropathic psoriasis	0.000	0.993	0.007
M25.46 Effusion of joint (Lower leg)	0.007	0.993	0.000
N84.2 Polyp of vagina	0.000	0.993	0.007
K82.4 Cholesterolosis of gallbladder	0.007	0.993	0.000
M25 Other joint disorders, not elsewhere classified	0.007	0.993	0.000
M20-M25 Other joint disorders	0.007	0.993	0.000
K82.1 Hydrops of gallbladder	0.007	0.993	0.000
M25.4 Effusion of joint	0.007	0.993	0.000
M25.5 Pain in joint	0.007	0.993	0.000
M24 Other specific joint derangements	0.006	0.994	0.000
M20.2 Hallux rigidus	0.006	0.994	0.000
N84.9 Polyp of female genital tract, unspecified	0.000	0.994	0.006
N84.8 Polyp of other parts of female genital tract	0.000	0.994	0.006
N84.3 Polyp of vulva	0.000	0.994	0.006
M25.3 Other instability of joint	0.006	0.994	0.000
M25.37 Other instability of joint (Ankle and foot)	0.006	0.994	0.000
M25.57 Pain in joint (Ankle and foot)	0.006	0.994	0.000
K82.9 Disease of gallbladder, unspecified	0.006	0.994	0.000
L40 Psoriasis	0.000	0.994	0.006
L40.9 Psoriasis, unspecified	0.000	0.994	0.006
M33 Dermatopolymyositis	0.006	0.994	0.000
K82.3 Fistula of gallbladder	0.006	0.994	0.000
K82.2 Perforation of gallbladder	0.006	0.994	0.000
K82.0 Obstruction of gallbladder	0.006	0.994	0.000
M20 Acquired deformities of fingers and toes	0.006	0.994	0.000
M25.40 Effusion of joint (Multiple sites)	0.006	0.994	0.000
M25.56 Pain in joint (Lower leg)	0.006	0.994	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.006	0.994	0.000
M25.9 Joint disorder, unspecified	0.005	0.994	0.000
M25.59 Pain in joint (Site unspecified)	0.005	0.994	0.000
M25.51 Pain in joint (Shoulder region)	0.005	0.994	0.000
M34 Systemic sclerosis	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
M24.0 Loose body in joint	0.005	0.995	0.000
M25.54 Pain in joint (Hand)	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
M30 Polyarteritis nodosa and related conditions	0.005	0.995	0.000
M25.2 Flail joint	0.005	0.995	0.000
M25.1 Fistula of joint	0.005	0.995	0.000
M25.0 Haemarthrosis	0.005	0.995	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.005	0.995	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.005	0.995	0.000
M32 Systemic lupus erythematosus	0.005	0.995	0.000
K83.8 Other specified diseases of biliary tract	0.005	0.995	0.000
M21 Other acquired deformities of limbs	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
M25.49 Effusion of joint (Site unspecified)	0.005	0.995	0.000
M25.48 Effusion of joint (Other)	0.005	0.995	0.000
M25.44 Effusion of joint (Hand)	0.005	0.995	0.000
M25.43 Effusion of joint (Forearm)	0.005	0.995	0.000
M25.42 Effusion of joint (Upper arm)	0.005	0.995	0.000
M25.41 Effusion of joint (Shoulder region)	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
M20.0 Deformity of finger(s)	0.005	0.995	0.000
M25.53 Pain in joint (Forearm)	0.005	0.995	0.000
M25.58 Pain in joint (Other)	0.005	0.995	0.000
M25.50 Pain in joint (Multiple sites)	0.005	0.995	0.000
M33.1 Other dermatomyositis	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M25.52 Pain in joint (Upper arm)	0.005	0.995	0.000
M24.9 Joint derangement, unspecified	0.005	0.995	0.000
M24.7 Protrusio acetabuli	0.005	0.995	0.000
M24.6 Ankylosis of joint	0.005	0.995	0.000
M24.5 Contracture of joint	0.005	0.995	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.005	0.995	0.000
M24.07 Loose body in joint (Ankle and foot)	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
M25.39 Other instability of joint (Site unspecified)	0.005	0.995	0.000
M25.38 Other instability of joint (Other)	0.005	0.995	0.000
M25.36 Other instability of joint (Lower leg)	0.005	0.995	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.005	0.995	0.000
M25.34 Other instability of joint (Hand)	0.005	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.005	0.995	0.000
M25.32 Other instability of joint (Upper arm)	0.005	0.995	0.000
M25.30 Other instability of joint (Multiple sites)	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
M20.5 Other deformities of toe(s) (acquired)	0.005	0.995	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
M25.8 Other specified joint disorders	0.004	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.005	0.995	0.000
M25.31 Other instability of joint (Shoulder region)	0.004	0.995	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.004	0.995	0.000
M34.9 Systemic sclerosis, unspecified	0.004	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
L40.8 Other psoriasis	0.000	0.996	0.004
L40.4 Guttate psoriasis	0.000	0.996	0.004
L40.3 Pustulosis palmaris et plantaris	0.000	0.996	0.004
L40.2 Acrodermatitis continua	0.000	0.996	0.004
L40.1 Generalised pustular psoriasis	0.000	0.996	0.004
L40.0 Psoriasis vulgaris	0.000	0.996	0.004
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
M33.9 Dermatopolymyositis, unspecified	0.004	0.996	0.000
M33.2 Polymyositis	0.004	0.996	0.000
M33.0 Juvenile dermatomyositis	0.004	0.996	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.004	0.996	0.000
M25.98 Joint disorder, unspecified (Other)	0.004	0.996	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.996	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M25.94 Joint disorder, unspecified (Hand)	0.004	0.996	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.996	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.004	0.996	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.004	0.996	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
M20.3 Other deformity of hallux (acquired)	0.004	0.996	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.004	0.996	0.000
M34.8 Other forms of systemic sclerosis	0.004	0.996	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.004	0.996	0.000
M34.0 Progressive systemic sclerosis	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.004	0.996	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.004	0.996	0.000
M24.08 Loose body in joint (Other)	0.004	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.996	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.04 Loose body in joint (Hand)	0.004	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.996	0.000
M24.01 Loose body in joint (Shoulder region)	0.004	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.004	0.996	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.004	0.996	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.004	0.996	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.004	0.996	0.000
M30.2 Juvenile polyarteritis	0.004	0.996	0.000
M30.0 Polyarteritis nodosa	0.004	0.996	0.000
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
M25.09 Haemarthrosis (Site unspecified)	0.004	0.996	0.000
M25.08 Haemarthrosis (Other)	0.004	0.996	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.004	0.996	0.000
M25.06 Haemarthrosis (Lower leg)	0.004	0.996	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M25.04 Haemarthrosis (Hand)	0.004	0.996	0.000
M25.03 Haemarthrosis (Forearm)	0.004	0.996	0.000
M25.02 Haemarthrosis (Upper arm)	0.004	0.996	0.000
M25.01 Haemarthrosis (Shoulder region)	0.004	0.996	0.000
M25.00 Haemarthrosis (Multiple sites)	0.004	0.996	0.000
M25.19 Fistula of joint (Site unspecified)	0.004	0.996	0.000
M25.18 Fistula of joint (Other)	0.004	0.996	0.000
M25.17 Fistula of joint (Ankle and foot)	0.004	0.996	0.000
M25.16 Fistula of joint (Lower leg)	0.004	0.996	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.14 Fistula of joint (Hand)	0.004	0.996	0.000
M25.13 Fistula of joint (Forearm)	0.004	0.996	0.000
M25.12 Fistula of joint (Upper arm)	0.004	0.996	0.000
M25.11 Fistula of joint (Shoulder region)	0.004	0.996	0.000
M25.10 Fistula of joint (Multiple sites)	0.004	0.996	0.000
M25.29 Flail joint (Site unspecified)	0.004	0.996	0.000
M25.28 Flail joint (Other)	0.004	0.996	0.000
M25.27 Flail joint (Ankle and foot)	0.004	0.996	0.000
M25.26 Flail joint (Lower leg)	0.004	0.996	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.24 Flail joint (Hand)	0.004	0.996	0.000
M25.23 Flail joint (Forearm)	0.004	0.996	0.000
M25.22 Flail joint (Upper arm)	0.004	0.996	0.000
M25.21 Flail joint (Shoulder region)	0.004	0.996	0.000
M25.20 Flail joint (Multiple sites)	0.004	0.996	0.000
M21.2 Flexion deformity	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.004	0.996	0.000
M32.8 Other forms of systemic lupus erythematosus	0.004	0.996	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.004	0.996	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.004	0.996	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.004	0.996	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.004	0.996	0.000
M36.3 Arthropathy in other blood disorders	0.004	0.996	0.000
M36.2 Haemophilic arthropathy	0.004	0.996	0.000
M36.1 Arthropathy in neoplastic disease	0.004	0.996	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.004	0.996	0.000
M21.9 Acquired deformity of limb, unspecified	0.004	0.996	0.000
M21.8 Other specified acquired deformities of limbs	0.004	0.996	0.000
M21.7 Unequal limb length (acquired)	0.004	0.996	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.996	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.004	0.996	0.000
M21.4 Flat foot [pes planus] (acquired)	0.004	0.996	0.000
M21.1 Varus deformity, not elsewhere classified	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
M22 Disorders of patella	0.004	0.996	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.996	0.004
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.996	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.996	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.996	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.996	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.996	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.996	0.000
M24.58 Contracture of joint (Other)	0.003	0.996	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.996	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.54 Contracture of joint (Hand)	0.003	0.996	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.996	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.996	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.996	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.996	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.996	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.996	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.996	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.996	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.996	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.996	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.996	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.996	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.996	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.996	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.996	0.000
M25.47 Effusion of joint (Ankle and foot)	0.003	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.996	0.000
T42.3 Barbiturates	0.003	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.996	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.996	0.000
T45.5 Anticoagulants	0.003	0.996	0.000
T45.4 Iron and its compounds	0.003	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.996	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.996	0.000
M25.88 Other specified joint disorders (Other)	0.003	0.996	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.996	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.996	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.996	0.000
M25.86 Other specified joint disorders (Lower leg)	0.003	0.996	0.000
K83 Other diseases of biliary tract	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
M25.7 Osteophyte	0.003	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
Z13.9 Special screening examination, unspecified	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.997	0.003
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.003	0.997	0.000
M21.28 Flexion deformity (Other)	0.003	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.003	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.003	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.003	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.003	0.997	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.003	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.003	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.003	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.003	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.003	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.003	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.003	0.997	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.003	0.997	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.003	0.997	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.003	0.997	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.003	0.997	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.003	0.997	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.003	0.997	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.003	0.997	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.003	0.997	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.997	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.997	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.003	0.997	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.997	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.997	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.997	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations