TreeWAS – Variant ID: rs16861846

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	1.000	0.000	0.000
D68 Other coagulation defects	0.998	0.002	0.000
D68.5 Primary Thrombophilia	0.969	0.031	0.000
D68.8 Other specified coagulation defects	0.919	0.081	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.872	0.128	0.000
D68.6 Other Thrombophilia	0.850	0.150	0.000
D68.9 Coagulation defect, unspecified	0.835	0.165	0.000
D68.4 Acquired coagulation factor deficiency	0.715	0.285	0.000
D68.1 Hereditary factor XI deficiency	0.710	0.290	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.652	0.348	0.000
D68.0 Von Willebrand's disease	0.621	0.379	0.000
D69 Purpura and other haemorrhagic conditions	0.578	0.422	0.000
D69.6 Thrombocytopenia, unspecified	0.537	0.463	0.000
D69.5 Secondary thrombocytopenia	0.506	0.494	0.000
D67 Hereditary factor IX deficiency	0.468	0.532	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.468	0.532	0.000
D66 Hereditary factor VIII deficiency	0.467	0.533	0.000
D69.9 Haemorrhagic condition, unspecified	0.466	0.534	0.000
D69.2 Other nonthrombocytopenic purpura	0.434	0.566	0.000
D69.8 Other specified haemorrhagic conditions	0.415	0.585	0.000
D69.1 Qualitative platelet defects	0.415	0.585	0.000
D69.0 Allergic purpura	0.355	0.645	0.000
D69.4 Other primary thrombocytopenia	0.351	0.649	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.176	0.823	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.106	0.894	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.037	0.963	0.000
D55-D59 Haemolytic anaemias	0.028	0.972	0.000
D80-D89 Certain disorders involving the immune mechanism	0.024	0.976	0.000
D59 Acquired haemolytic anaemia	0.022	0.977	0.000
D50-D53 Nutritional anaemias	0.021	0.979	0.000
D57 Sickle-cell disorders	0.020	0.980	0.000
D56 Thalassaemia	0.020	0.980	0.000
D55 Anaemia due to enzyme disorders	0.020	0.980	0.000
D83 Common variable immunodeficiency	0.019	0.981	0.000
D59.1 Other autoimmune haemolytic anaemias	0.019	0.981	0.000
D84 Other immunodeficiencies	0.019	0.981	0.000
D51 Vitamin B12 deficiency anaemia	0.018	0.981	0.000
D58 Other hereditary haemolytic anaemias	0.018	0.982	0.000
D82 Immunodeficiency associated with other major defects	0.017	0.983	0.000
D81 Combined immunodeficiencies	0.017	0.983	0.000
D59.8 Other acquired haemolytic anaemias	0.016	0.984	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.016	0.984	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.016	0.984	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.016	0.984	0.000
D59.3 Haemolytic-uraemic syndrome	0.016	0.984	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.016	0.984	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.016	0.984	0.000
D80 Immunodeficiency with predominantly antibody defects	0.016	0.984	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.016	0.984	0.000
D83.9 Common variable immunodeficiency, unspecified	0.016	0.984	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.016	0.984	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.016	0.984	0.000
D84.9 Immunodeficiency, unspecified	0.015	0.985	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.015	0.985	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.015	0.985	0.000
D55.8 Other anaemias due to enzyme disorders	0.015	0.985	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.015	0.985	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.015	0.985	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.015	0.985	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.015	0.985	0.000
D56.9 Thalassaemia, unspecified	0.015	0.985	0.000
D56.8 Other thalassaemias	0.015	0.985	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.015	0.985	0.000
D56.3 Thalassaemia trait	0.015	0.985	0.000
D56.2 Delta-beta thalassaemia	0.015	0.985	0.000
D56.1 Beta thalassaemia	0.015	0.985	0.000
D56.0 Alpha thalassaemia	0.015	0.985	0.000
D57.8 Other sickle-cell disorders	0.015	0.985	0.000
D57.3 Sickle-cell trait	0.015	0.985	0.000
D57.2 Double heterozygous sickling disorders	0.015	0.985	0.000
D57.1 Sickle-cell anaemia without crisis	0.015	0.985	0.000
D57.0 Sickle-cell anaemia with crisis	0.015	0.985	0.000
D83.8 Other common variable immunodeficiencies	0.014	0.986	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.014	0.986	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.014	0.986	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.014	0.986	0.000
D53 Other nutritional anaemias	0.014	0.986	0.000
D84.8 Other specified immunodeficiencies	0.014	0.986	0.000
D84.1 Defects in the complement system	0.014	0.986	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.014	0.986	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.013	0.986	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.013	0.986	0.000
D51.2 Transcobalamin II deficiency	0.013	0.986	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.013	0.986	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.013	0.987	0.000
D58.2 Other haemoglobinopathies	0.013	0.987	0.000
D58.1 Hereditary elliptocytosis	0.013	0.987	0.000
D58.0 Hereditary spherocytosis	0.013	0.987	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.013	0.987	0.000
D81.9 Combined immunodeficiency, unspecified	0.012	0.987	0.000
D81.8 Other combined immunodeficiencies	0.012	0.987	0.000
D81.7 Major histocompatibility complex class II deficiency	0.012	0.987	0.000
D81.6 Major histocompatibility complex class I deficiency	0.012	0.987	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.012	0.987	0.000
D81.4 Nezelof's syndrome	0.012	0.987	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.012	0.987	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.012	0.987	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.012	0.987	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.012	0.987	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.987	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.987	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.987	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.012	0.987	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.987	0.000
D82.1 Di George's syndrome	0.012	0.987	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.987	0.000
I80 Phlebitis and thrombophlebitis	0.013	0.987	0.000
D60-D64 Aplastic and other anaemias	0.012	0.988	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.012	0.988	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.012	0.988	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.012	0.988	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.012	0.988	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.012	0.988	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.012	0.988	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.012	0.988	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.012	0.988	0.000
D52 Folate deficiency anaemia	0.012	0.988	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.012	0.988	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.011	0.988	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.011	0.988	0.000
D89.3 Immune reconstitution syndrome	0.011	0.988	0.000
D89.1 Cryoglobulinaemia	0.011	0.988	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.011	0.988	0.000
D53.8 Other specified nutritional anaemias	0.010	0.990	0.000
D53.2 Scorbutic anaemia	0.010	0.990	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.010	0.990	0.000
D53.0 Protein deficiency anaemia	0.010	0.990	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.010	0.990	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.010	0.990	0.000
D86 Sarcoidosis	0.010	0.990	0.000
D53.9 Nutritional anaemia, unspecified	0.009	0.991	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.009	0.991	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.009	0.991	0.000
D52.8 Other folate deficiency anaemias	0.009	0.991	0.000
D52.1 Drug-induced folate deficiency anaemia	0.009	0.991	0.000
D52.0 Dietary folate deficiency anaemia	0.009	0.991	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.009	0.991	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.008	0.992	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.008	0.992	0.000
D63.0 Anaemia in neoplastic disease	0.008	0.992	0.000
D86.3 Sarcoidosis of skin	0.007	0.992	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.007	0.992	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.007	0.993	0.000
D61 Other aplastic anaemias	0.007	0.993	0.000
D86.1 Sarcoidosis of lymph nodes	0.007	0.993	0.000
D86.8 Sarcoidosis of other and combined sites	0.007	0.993	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.007	0.993	0.000
D60.8 Other acquired pure red cell aplasias	0.007	0.993	0.000
D60.1 Transient acquired pure red cell aplasia	0.007	0.993	0.000
D60.0 Chronic acquired pure red cell aplasia	0.007	0.993	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.007	0.993	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.993	0.007
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.007	0.993	0.000
D73 Diseases of spleen	0.007	0.993	0.000
D64 Other anaemias	0.006	0.993	0.000
D74 Methaemoglobinaemia	0.006	0.994	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.006	0.994	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.006	0.994	0.000
D50 Iron deficiency anaemia	0.006	0.994	0.000
D73.8 Other diseases of spleen	0.006	0.994	0.000
T42.4 Benzodiazepines	0.000	0.994	0.006
D52.9 Folate deficiency anaemia, unspecified	0.005	0.994	0.000
D62 Acute posthaemorrhagic anaemia	0.005	0.994	0.000
D76.3 Other histiocytosis syndromes	0.005	0.994	0.000
H20.8 Other iridocyclitis	0.006	0.994	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.006	0.994	0.000
D61.8 Other specified aplastic anaemias	0.005	0.995	0.000
D61.3 Idiopathic aplastic anaemia	0.005	0.995	0.000
D61.2 Aplastic anaemia due to other external agents	0.005	0.995	0.000
D61.1 Drug-induced aplastic anaemia	0.005	0.995	0.000
D61.0 Constitutional aplastic anaemia	0.005	0.995	0.000
D73.5 Infarction of spleen	0.005	0.995	0.000
H20.9 Iridocyclitis, unspecified	0.005	0.995	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
D73.9 Disease of spleen, unspecified	0.005	0.995	0.000
D73.4 Cyst of spleen	0.005	0.995	0.000
D73.3 Abscess of spleen	0.005	0.995	0.000
D73.2 Chronic congestive splenomegaly	0.005	0.995	0.000
D73.1 Hypersplenism	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
H20 Iridocyclitis	0.005	0.995	0.000
D64.4 Congenital dyserythropoietic anaemia	0.005	0.995	0.000
D64.3 Other sideroblastic anaemias	0.005	0.995	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.005	0.995	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.005	0.995	0.000
D64.0 Hereditary sideroblastic anaemia	0.005	0.995	0.000
D64.8 Other specified anaemias	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.005	0.995	0.000
D74.8 Other methaemoglobinaemias	0.005	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.995	0.005
D50.1 Sideropenic dysphagia	0.004	0.995	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
D50.9 Iron deficiency anaemia, unspecified	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
H25.9 Senile cataract, unspecified	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
H20.2 Lens-induced iridocyclitis	0.004	0.996	0.000
H20.1 Chronic iridocyclitis	0.004	0.996	0.000
H20.0 Acute and subacute iridocyclitis	0.004	0.996	0.000
D72 Other disorders of white blood cells	0.003	0.996	0.001
J33.0 Polyp of nasal cavity	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
Z98.8 Other specified postsurgical states	0.004	0.996	0.000
T42.1 Iminostilbenes	0.000	0.996	0.003
F05.9 Delirium, unspecified	0.004	0.996	0.000
Z88.2 Personal history of allergy to sulphonamides	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.003	0.996	0.000
D73.0 Hyposplenism	0.003	0.996	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
Z88.5 Personal history of allergy to narcotic agent	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
S20.1 Other and unspecified superficial injuries of breast	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
Y42.5 Other oestrogens and progestogens	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
D72.9 Disorder of white blood cells, unspecified	0.002	0.997	0.001
D72.0 Genetic anomalies of leukocytes	0.002	0.997	0.001
A04.7 Enterocolitis due to Clostridium difficile	0.003	0.997	0.000
T39.0 Salicylates	0.000	0.997	0.003
S20.3 Other superficial injuries of front wall of thorax	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
T50.8 Diagnostic agents	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
S20.7 Multiple superficial injuries of thorax	0.003	0.997	0.000
S20.4 Other superficial injuries of back wall of thorax	0.003	0.997	0.000
S20.0 Contusion of breast	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
D75.2 Essential thrombocytosis	0.002	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
T45.5 Anticoagulants	0.000	0.997	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.002
T47.7 Emetics	0.000	0.997	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.002
T47.5 Digestants	0.000	0.997	0.002
T47.4 Other laxatives	0.000	0.997	0.002
T47.3 Saline and osmotic laxatives	0.000	0.997	0.002
T47.2 Stimulant laxatives	0.000	0.997	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.002
H16 Keratitis	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.000	0.997	0.003
H16.9 Keratitis, unspecified	0.003	0.997	0.000
K43 Ventral hernia	0.000	0.997	0.003
D72.1 Eosinophilia	0.002	0.997	0.001
S20.2 Contusion of thorax	0.002	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.002
T37.5 Antiviral drugs	0.000	0.997	0.002
T37.4 Anthelminthics	0.000	0.997	0.002
T37.3 Other antiprotozoal drugs	0.000	0.997	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.002
T37.1 Antimycobacterial drugs	0.000	0.997	0.002
T37.0 Sulphonamides	0.000	0.997	0.002
T41.5 Therapeutic gases	0.000	0.997	0.002
T41.4 Anaesthetic, unspecified	0.000	0.997	0.002
T41.3 Local anaesthetics	0.000	0.997	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.002
T41.1 Intravenous anaesthetics	0.000	0.997	0.002
T41.0 Inhaled anaesthetics	0.000	0.997	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.002
T48.5 Anti-common-cold drugs	0.000	0.997	0.002
T48.4 Expectorants	0.000	0.997	0.002
T48.3 Antitussives	0.000	0.997	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.002
T48.0 Oxytocic drugs	0.000	0.997	0.002
T49.9 Topical agent, unspecified	0.000	0.997	0.002
T49.8 Other topical agents	0.000	0.997	0.002
T49.7 Dental drugs, topically applied	0.000	0.997	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.002
T49.2 Local astringents and local detergents	0.000	0.997	0.002
T49.1 Antipruritics	0.000	0.997	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.997	0.002
T46.1 Calcium-channel blockers	0.000	0.997	0.002
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.998	0.002
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
T40.2 Other opioids	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
H16.8 Other keratitis	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
R40.0 Somnolence	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
D64.9 Anaemia, unspecified	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.998	0.002
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.998	0.002
K43.4 Parastomal hernia with gangrene	0.000	0.998	0.002
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.998	0.002
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.998	0.002
K43.1 Ventral hernia with gangrene	0.000	0.998	0.002
S09.9 Unspecified injury of head	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
R68.8 Other specified general symptoms and signs	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.001	0.998	0.001
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
T36.0 Penicillins	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
C21.0 Anus, unspecified	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
X50.4 Street and highway	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
M16.1 Other primary coxarthrosis	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H17 Corneal scars and opacities	0.001	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.001	0.998	0.000
H15.1 Episcleritis	0.001	0.998	0.000
N84.0 Polyp of corpus uteri	0.000	0.998	0.002
R30.0 Dysuria	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.001
Y42.4 Oral contraceptives	0.000	0.998	0.001
Y42.2 Antithyroid drugs	0.000	0.998	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.001
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
G44.0 Cluster headache syndrome	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.001	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.001	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.998	0.000
H21.4 Pupillary membranes	0.001	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.001	0.998	0.000
H17.1 Other central corneal opacity	0.001	0.998	0.000
H17.0 Adherent leukoma	0.001	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.001	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.001	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.999	0.000
Z45.2 Adjustment and management of vascular access device	0.001	0.999	0.000
K59.1 Functional diarrhoea	0.001	0.999	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
M25.06 Haemarthrosis (Lower leg)	0.001	0.999	0.000
N84.1 Polyp of cervix uteri	0.000	0.999	0.001
L03.8 Cellulitis of other sites	0.000	0.999	0.001
Z54.0 Convalescence following surgery	0.001	0.999	0.000
H21.8 Other specified disorders of iris and ciliary body	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.001	0.999	0.000
J03 Acute tonsillitis	0.001	0.999	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
J98.4 Other disorders of lung	0.001	0.999	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.999	0.001
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
T23.7 Corrosion of third degree of wrist and hand	0.001	0.999	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.999	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.999	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations