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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16899207
log Bayes Factor = 43.7938
Chromosome 6   position 31,266,387  (GRCh37) Explore rs16899207 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
M45 Ankylosing spondylitis
0.000 0.035 0.965
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.059 0.941
L40.0 Psoriasis vulgaris
0.000 0.068 0.932
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.109 0.891
L40.8 Other psoriasis
0.000 0.204 0.796
L40.3 Pustulosis palmaris et plantaris
0.000 0.246 0.754
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.308 0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.308 0.692
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.308 0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.308 0.692
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.308 0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.308 0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.308 0.692
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.343 0.657
E03 Other hypothyroidism
0.000 0.357 0.643
M07.3 Other psoriatic arthropathies
0.000 0.368 0.632
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.378 0.622
E03.8 Other specified hypothyroidism
0.000 0.448 0.552
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.453 0.547
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.512 0.487
E03.5 Myxoedema coma
0.000 0.539 0.461
E03.4 Atrophy of thyroid (acquired)
0.000 0.539 0.461
E03.3 Postinfectious hypothyroidism
0.000 0.539 0.461
M07.38 Other psoriatic arthropathies (Other)
0.000 0.547 0.453
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.547 0.453
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.547 0.453
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.547 0.453
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.547 0.453
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.547 0.453
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.555 0.445
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.582 0.418
E03.1 Congenital hypothyroidism without goitre
0.000 0.596 0.404
M07 Psoriatic and enteropathic arthropathies
0.001 0.733 0.266
K90 Intestinal malabsorption
0.000 0.764 0.236
L40-L45 Papulosquamous disorders
0.000 0.785 0.215
G35 Multiple sclerosis
0.000 0.807 0.193
M07.6 Other enteropathic arthropathies
0.001 0.808 0.191
M07.5 Arthropathy in ulcerative colitis
0.001 0.808 0.191
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.808 0.191
M07.2 Psoriatic spondylitis
0.001 0.808 0.191
M07.1 Arthritis mutilans
0.001 0.808 0.191
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.808 0.191
K90.3 Pancreatic steatorrhoea
0.000 0.831 0.169
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.831 0.169
K90.1 Tropical sprue
0.000 0.831 0.169
K90.8 Other intestinal malabsorption
0.000 0.835 0.165
L44 Other papulosquamous disorders
0.000 0.845 0.154
L41 Parapsoriasis
0.000 0.845 0.154
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.845 0.154
L42 Pityriasis rosea
0.000 0.851 0.149
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.861 0.139
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.862 0.137
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.862 0.137
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.862 0.137
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.862 0.137
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.862 0.137
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.862 0.137
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.862 0.137
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.862 0.137
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.862 0.137
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.862 0.137
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.862 0.137
M07.18 Arthritis mutilans (Other)
0.001 0.862 0.137
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.862 0.137
M07.16 Arthritis mutilans (Lower leg)
0.001 0.862 0.137
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.862 0.137
M07.14 Arthritis mutilans (Hand)
0.001 0.862 0.137
M07.13 Arthritis mutilans (Forearm)
0.001 0.862 0.137
M07.12 Arthritis mutilans (Upper arm)
0.001 0.862 0.137
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.862 0.137
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.862 0.137
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.862 0.137
M07.28 Psoriatic spondylitis (Other)
0.001 0.862 0.137
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.862 0.137
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.862 0.137
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.862 0.137
M07.24 Psoriatic spondylitis (Hand)
0.001 0.862 0.137
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.862 0.137
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.862 0.137
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.862 0.137
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.862 0.137
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.862 0.137
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.862 0.137
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.862 0.137
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.862 0.137
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.862 0.137
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.862 0.137
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.862 0.137
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.862 0.137
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.862 0.137
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.862 0.137
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.862 0.137
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.862 0.137
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.862 0.137
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.862 0.137
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.862 0.137
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.862 0.137
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.862 0.137
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.862 0.137
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.862 0.137
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.862 0.137
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.862 0.137
M07.68 Other enteropathic arthropathies (Other)
0.001 0.862 0.137
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.862 0.137
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.862 0.137
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.862 0.137
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.862 0.137
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.862 0.137
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.862 0.137
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.862 0.137
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.862 0.137
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.871 0.129
K90.9 Intestinal malabsorption, unspecified
0.000 0.874 0.125
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.877 0.123
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.878 0.122
G30-G32 Other degenerative diseases of the nervous system
0.000 0.878 0.121
G31.8 Other specified degenerative diseases of nervous system
0.000 0.883 0.117
R31 Unspecified haematuria
0.116 0.884 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.886 0.114
L41.9 Parapsoriasis, unspecified
0.000 0.889 0.111
L41.8 Other parapsoriasis
0.000 0.889 0.111
L41.5 Retiform parapsoriasis
0.000 0.889 0.111
L41.4 Large plaque parapsoriasis
0.000 0.889 0.111
L41.3 Small plaque parapsoriasis
0.000 0.889 0.111
L41.2 Lymphomatoid papulosis
0.000 0.889 0.111
L41.1 Pityriasis lichenoides chronica
0.000 0.889 0.111
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.889 0.111
L44.9 Papulosquamous disorder, unspecified
0.000 0.889 0.111
L44.8 Other specified papulosquamous disorders
0.000 0.889 0.111
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.889 0.111
L44.3 Lichen ruber moniliformis
0.000 0.889 0.111
L44.2 Lichen striatus
0.000 0.889 0.111
L44.1 Lichen nitidus
0.000 0.889 0.111
L44.0 Pityriasis rubra pilaris
0.000 0.889 0.111
G30 Alzheimer's disease
0.000 0.890 0.110
G31.0 Circumscribed brain atrophy
0.000 0.895 0.105
Chapter VI Diseases of the nervous system
0.000 0.899 0.101
G30.9 Alzheimer's disease, unspecified
0.000 0.900 0.100
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.907 0.093
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.907 0.092
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.908 0.092
K75 Other inflammatory liver diseases
0.000 0.910 0.090
K75.8 Other specified inflammatory liver diseases
0.000 0.912 0.088
K75.0 Abscess of liver
0.000 0.914 0.086
G30.1 Alzheimer's disease with late onset
0.000 0.915 0.085
K75.4 Autoimmune hepatitis
0.000 0.915 0.085
G62 Other polyneuropathies
0.000 0.915 0.085
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.916 0.084
K70 Alcoholic liver disease
0.000 0.917 0.083
K70-K77 Diseases of liver
0.000 0.918 0.082
G30.0 Alzheimer's disease with early onset
0.000 0.918 0.082
G36 Other acute disseminated demyelination
0.000 0.919 0.081
G62.9 Polyneuropathy, unspecified
0.000 0.919 0.081
G70-G73 Diseases of myoneural junction and muscle
0.000 0.920 0.080
M45-M49 Spondylopathies
0.000 0.922 0.078
K70.1 Alcoholic hepatitis
0.000 0.922 0.078
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.922 0.078
G30.8 Other Alzheimer's disease
0.000 0.922 0.078
N39.3 Stress incontinence
0.077 0.923 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.924 0.076
K73 Chronic hepatitis, not elsewhere classified
0.000 0.925 0.075
K70.4 Alcoholic hepatic failure
0.000 0.926 0.074
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.927 0.073
D64.9 Anaemia, unspecified
0.000 0.927 0.073
K70.0 Alcoholic fatty liver
0.000 0.927 0.073
G61 Inflammatory polyneuropathy
0.000 0.928 0.072
G83 Other paralytic syndromes
0.000 0.930 0.070
G60 Hereditary and idiopathic neuropathy
0.000 0.930 0.070
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.931 0.069
G03 Meningitis due to other and unspecified causes
0.000 0.931 0.069
D64 Other anaemias
0.000 0.932 0.068
K72.9 Hepatic failure, unspecified
0.000 0.932 0.068
G00 Bacterial meningitis, not elsewhere classified
0.000 0.933 0.067
G62.1 Alcoholic polyneuropathy
0.000 0.933 0.067
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.933 0.067
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.933 0.067
G64 Other disorders of peripheral nervous system
0.000 0.934 0.066
K72.0 Acute and subacute hepatic failure
0.000 0.934 0.066
K75.2 Nonspecific reactive hepatitis
0.000 0.935 0.065
K75.1 Phlebitis of portal vein
0.000 0.935 0.065
G83.4 Cauda equina syndrome
0.000 0.935 0.065
G71 Primary disorders of muscles
0.000 0.936 0.064
K73.9 Chronic hepatitis, unspecified
0.000 0.936 0.064
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.936 0.064
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.937 0.063
G61.8 Other inflammatory polyneuropathies
0.000 0.937 0.063
L43 Lichen planus
0.001 0.937 0.062
D60-D64 Aplastic and other anaemias
0.000 0.938 0.062
D61.9 Aplastic anaemia, unspecified
0.000 0.938 0.062
G62.2 Polyneuropathy due to other toxic agents
0.000 0.939 0.061
D61 Other aplastic anaemias
0.000 0.939 0.061
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.939 0.061
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.940 0.060
G83.9 Paralytic syndrome, unspecified
0.000 0.940 0.060
K70.9 Alcoholic liver disease, unspecified
0.000 0.940 0.060
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.940 0.060
K77 Liver disorders in diseases classified elsewhere
0.000 0.941 0.059
D50 Iron deficiency anaemia
0.000 0.941 0.059
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.941 0.059
G36.9 Acute disseminated demyelination, unspecified
0.000 0.941 0.058
G36.8 Other specified acute disseminated demyelination
0.000 0.941 0.058
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.941 0.058
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.941 0.058
D50.9 Iron deficiency anaemia, unspecified
0.000 0.942 0.058
D50-D53 Nutritional anaemias
0.000 0.942 0.058
G72 Other myopathies
0.000 0.942 0.058
G03.9 Meningitis, unspecified
0.000 0.942 0.057
D64.8 Other specified anaemias
0.000 0.942 0.057
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.943 0.057
G62.8 Other specified polyneuropathies
0.000 0.943 0.057
G60.0 Hereditary motor and sensory neuropathy
0.000 0.943 0.057
G81 Hemiplegia
0.000 0.943 0.057
G70 Myasthenia gravis and other myoneural disorders
0.000 0.943 0.057
M46 Other inflammatory spondylopathies
0.000 0.943 0.057
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.944 0.056
G06.0 Intracranial abscess and granuloma
0.000 0.944 0.056
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.945 0.055
G06.1 Intraspinal abscess and granuloma
0.000 0.945 0.055
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.945 0.055
G00.1 Pneumococcal meningitis
0.000 0.945 0.054
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.946 0.054
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.946 0.054
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.946 0.053
D50.8 Other iron deficiency anaemias
0.000 0.946 0.054
G36.0 Neuromyelitis optica [Devic]
0.000 0.947 0.052
K71 Toxic liver disease
0.000 0.947 0.052
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.948 0.052
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.948 0.052
G61.1 Serum neuropathy
0.000 0.948 0.052
G83.1 Monoplegia of lower limb
0.000 0.948 0.052
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.949 0.051
K70.3 Alcoholic cirrhosis of liver
0.000 0.949 0.051
K72.1 Chronic hepatic failure
0.000 0.949 0.051
G83.5 Locked-in syndrome
0.000 0.950 0.050
G83.3 Monoplegia, unspecified
0.000 0.950 0.050
G83.0 Diplegia of upper limbs
0.000 0.950 0.050
G60.3 Idiopathic progressive neuropathy
0.000 0.950 0.050
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.950 0.050
G60.1 Refsum's disease
0.000 0.950 0.050
G00.9 Bacterial meningitis, unspecified
0.000 0.950 0.050
G37 Other demyelinating diseases of central nervous system
0.000 0.950 0.049
G03.8 Meningitis due to other specified causes
0.000 0.950 0.049
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.950 0.049
G03.1 Chronic meningitis
0.000 0.950 0.049
G03.0 Nonpyogenic meningitis
0.000 0.950 0.049
D80-D89 Certain disorders involving the immune mechanism
0.000 0.951 0.049
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.951 0.049
D64.4 Congenital dyserythropoietic anaemia
0.000 0.951 0.049
D64.3 Other sideroblastic anaemias
0.000 0.951 0.049
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.951 0.049
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.951 0.049
D64.0 Hereditary sideroblastic anaemia
0.000 0.951 0.049
M49 Spondylopathies in diseases classified elsewhere
0.000 0.951 0.049
G00.8 Other bacterial meningitis
0.000 0.951 0.048
G00.3 Staphylococcal meningitis
0.000 0.951 0.048
G00.2 Streptococcal meningitis
0.000 0.951 0.048
G00.0 Haemophilus meningitis
0.000 0.951 0.048
G06.2 Extradural and subdural abscess, unspecified
0.000 0.951 0.048
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.951 0.048
D51 Vitamin B12 deficiency anaemia
0.000 0.952 0.048
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.952 0.048
D52 Folate deficiency anaemia
0.000 0.952 0.048
G62.0 Drug-induced polyneuropathy
0.000 0.952 0.048
G61.0 Guillain-Barre syndrome
0.000 0.953 0.047
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.953 0.047
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.953 0.047
G81.1 Spastic hemiplegia
0.000 0.953 0.047
G71.9 Primary disorder of muscle, unspecified
0.000 0.953 0.046
G71.8 Other primary disorders of muscles
0.000 0.953 0.046
G71.2 Congenital myopathies
0.000 0.953 0.046
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.954 0.046
G71.1 Myotonic disorders
0.000 0.954 0.046
G82 Paraplegia and tetraplegia
0.000 0.954 0.046
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.954 0.046
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.954 0.046
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.954 0.046
E00-E07 Disorders of thyroid gland
0.000 0.954 0.046
L43.3 Subacute (active) lichen planus
0.001 0.955 0.044
L43.2 Lichenoid drug reaction
0.001 0.955 0.044
L43.1 Bullous lichen planus
0.001 0.955 0.044
L43.0 Hypertrophic lichen planus
0.001 0.955 0.044
G83.8 Other specified paralytic syndromes
0.000 0.955 0.045
G80 Infantile cerebral palsy
0.000 0.955 0.045
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.955 0.045
D80 Immunodeficiency with predominantly antibody defects
0.000 0.956 0.044
G72.9 Myopathy, unspecified
0.000 0.956 0.044
D61.8 Other specified aplastic anaemias
0.000 0.956 0.044
D61.3 Idiopathic aplastic anaemia
0.000 0.956 0.044
D61.2 Aplastic anaemia due to other external agents
0.000 0.956 0.044
G70.0 Myasthenia gravis
0.000 0.956 0.044
M46.0 Spinal enthesopathy
0.000 0.957 0.043
D53 Other nutritional anaemias
0.000 0.957 0.043
G12 Spinal muscular atrophy and related syndromes
0.000 0.957 0.043
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.957 0.043
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.957 0.043
D50.1 Sideropenic dysphagia
0.000 0.957 0.043
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.958 0.042
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.958 0.042
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.958 0.042
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.958 0.042
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.958 0.042
G63.1 Polyneuropathy in neoplastic disease
0.000 0.958 0.042
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.958 0.042
G72.8 Other specified myopathies
0.000 0.958 0.042
G72.0 Drug-induced myopathy
0.000 0.958 0.042
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.958 0.042
G72.3 Periodic paralysis
0.000 0.958 0.042
G72.2 Myopathy due to other toxic agents
0.000 0.958 0.042
G72.1 Alcoholic myopathy
0.000 0.958 0.042
G71.0 Muscular dystrophy
0.000 0.958 0.041
G73.7 Myopathy other diseases classified elsewhere
0.000 0.959 0.041
G73.6 Myopathy in metabolic diseases
0.000 0.959 0.041
G73.5 Myopathy in endocrine diseases
0.000 0.959 0.041
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.959 0.041
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.959 0.041
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.959 0.041
G73.1 Eaton-Lambert syndrome
0.000 0.959 0.041
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.959 0.041
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.959 0.041
G81.0 Flaccid hemiplegia
0.000 0.959 0.041
D61.0 Constitutional aplastic anaemia
0.000 0.959 0.041
M46.2 Osteomyelitis of vertebra
0.000 0.959 0.041
G70.8 Other specified myoneural disorders
0.000 0.959 0.041
G70.2 Congenital and developmental myasthenia
0.000 0.959 0.041
G70.1 Toxic myoneural disorders
0.000 0.959 0.041
M46.8 Other specified inflammatory spondylopathies
0.000 0.959 0.041
M46.5 Other infective spondylopathies
0.000 0.959 0.041
D52.9 Folate deficiency anaemia, unspecified
0.000 0.959 0.041
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.959 0.040
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.960 0.040
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.960 0.040
D61.1 Drug-induced aplastic anaemia
0.000 0.960 0.040
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.961 0.039
D55-D59 Haemolytic anaemias
0.000 0.961 0.039
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.961 0.039
M46.3 Infection of intervertebral disk (pyogenic)
0.000 0.961 0.039
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.961 0.038
G02.1 Meningitis in mycoses
0.000 0.961 0.038
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.961 0.038
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.962 0.038
G82.1 Spastic paraplegia
0.000 0.962 0.038
K71.9 Toxic liver disease, unspecified
0.000 0.962 0.038
K71.8 Toxic liver disease with other disorders of liver
0.000 0.962 0.038
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.962 0.038
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.962 0.038
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.962 0.038
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.962 0.038
K71.2 Toxic liver disease with acute hepatitis
0.000 0.962 0.038
K71.0 Toxic liver disease with cholestasis
0.000 0.962 0.038
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.962 0.038
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.962 0.038
G04.1 Tropical spastic paraplegia
0.000 0.962 0.038
G70.9 Myoneural disorder, unspecified
0.000 0.963 0.037
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.963 0.036
G83.2 Monoplegia of upper limb
0.000 0.963 0.036
G11 Hereditary ataxia
0.000 0.963 0.037
D83 Common variable immunodeficiency
0.000 0.964 0.036
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.964 0.036
E07 Other disorders of thyroid
0.000 0.964 0.036
D86 Sarcoidosis
0.000 0.964 0.036
K75.9 Inflammatory liver disease, unspecified
0.000 0.964 0.036
G37.5 Concentric sclerosis [Balo]
0.000 0.964 0.035
G37.4 Subacute necrotising myelitis
0.000 0.964 0.035
G37.2 Central pontine myelinolysis
0.000 0.964 0.035
G37.1 Central demyelination of corpus callosum
0.000 0.964 0.035
G37.0 Diffuse sclerosis
0.000 0.964 0.035
D81 Combined immunodeficiencies
0.000 0.964 0.036
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.964 0.036
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.965 0.035
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.965 0.035
M49.4 Neuropathic spondylopathy
0.000 0.965 0.035
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.965 0.035
M49.2 Enterobacterial spondylitis
0.000 0.965 0.035
M49.1 Brucella spondylitis
0.000 0.965 0.035
M49.0 Tuberculosis of spine
0.000 0.965 0.035
D51.2 Transcobalamin II deficiency
0.000 0.965 0.035
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.965 0.035
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.965 0.035
G14 Postpolio syndrome
0.000 0.965 0.035
D84 Other immunodeficiencies
0.000 0.965 0.035
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.965 0.035
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.965 0.035
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.965 0.035
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.965 0.035
D52.8 Other folate deficiency anaemias
0.000 0.965 0.035
D52.1 Drug-induced folate deficiency anaemia
0.000 0.965 0.035
D52.0 Dietary folate deficiency anaemia
0.000 0.965 0.035
G63.2 Diabetic polyneuropathy
0.000 0.965 0.035
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.965 0.034
G80.2 Infantile hemiplegia
0.000 0.966 0.034
M48 Other spondylopathies
0.000 0.966 0.034
G12.2 Motor neuron disease
0.000 0.966 0.034
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.966 0.034
M46.06 Spinal enthesopathy (Lumbar region)
0.000 0.966 0.034
G81.9 Hemiplegia, unspecified
0.000 0.966 0.034
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.966 0.034
G80.0 Spastic cerebral palsy
0.000 0.966 0.033
G82.3 Flaccid tetraplegia
0.000 0.967 0.033
G82.0 Flaccid paraplegia
0.000 0.967 0.033
E07.8 Other specified disorders of thyroid
0.000 0.967 0.033
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.967 0.033
E00 Congenital iodine-deficiency syndrome
0.000 0.967 0.033
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.967 0.033
G80.8 Other infantile cerebral palsy
0.000 0.967 0.032
G80.4 Ataxic cerebral palsy
0.000 0.967 0.032
G80.3 Dyskinetic cerebral palsy
0.000 0.967 0.032
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.968 0.032
D60.8 Other acquired pure red cell aplasias
0.000 0.968 0.032
D60.1 Transient acquired pure red cell aplasia
0.000 0.968 0.032
D60.0 Chronic acquired pure red cell aplasia
0.000 0.968 0.032
D53.9 Nutritional anaemia, unspecified
0.000 0.968 0.032
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.968 0.032
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.968 0.032
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.968 0.032
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.968 0.032
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.968 0.032
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.968 0.032
D86.3 Sarcoidosis of skin
0.000 0.968 0.032
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.968 0.032
G82.5 Tetraplegia, unspecified
0.000 0.968 0.032
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.968 0.032
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.968 0.031
D86.0 Sarcoidosis of lung
0.000 0.968 0.032
D82 Immunodeficiency associated with other major defects
0.000 0.968 0.031
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.968 0.031
M46.09 Spinal enthesopathy (Site unspecified)
0.000 0.969 0.031
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.000 0.969 0.031
M46.07 Spinal enthesopathy (Lumbosacral region)
0.000 0.969 0.031
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.000 0.969 0.031
M46.04 Spinal enthesopathy (Thoracic region)
0.000 0.969 0.031
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.000 0.969 0.031
M46.02 Spinal enthesopathy (Cervical region)
0.000 0.969 0.031
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.000 0.969 0.031
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.000 0.969 0.031
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.969 0.031
G82.4 Spastic tetraplegia
0.000 0.969 0.031
D53.8 Other specified nutritional anaemias
0.000 0.969 0.031
D53.2 Scorbutic anaemia
0.000 0.969 0.031
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.969 0.031
D53.0 Protein deficiency anaemia
0.000 0.969 0.031
G12.9 Spinal muscular atrophy, unspecified
0.000 0.969 0.031
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.969 0.031
G12.1 Other inherited spinal muscular atrophy
0.000 0.969 0.031
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.969 0.031
G04.0 Acute disseminated encephalitis
0.000 0.969 0.031
D89.1 Cryoglobulinaemia
0.000 0.969 0.031
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.969 0.030
D59 Acquired haemolytic anaemia
0.000 0.970 0.030
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.970 0.030
D89.3 Immune reconstitution syndrome
0.000 0.970 0.030
G10 Huntington's disease
0.000 0.970 0.030
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.000 0.970 0.030
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.000 0.970 0.029
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.000 0.970 0.029
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.000 0.970 0.029
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.000 0.970 0.029
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.000 0.970 0.029
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.000 0.970 0.029
M46.22 Osteomyelitis of vertebra (Cervical region)
0.000 0.970 0.029
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.000 0.970 0.029
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.000 0.970 0.029
M46.59 Other infective spondylopathies (Site unspecified)
0.000 0.970 0.029
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.000 0.970 0.029
M46.57 Other infective spondylopathies (Lumbosacral region)
0.000 0.970 0.029
M46.56 Other infective spondylopathies (Lumbar region)
0.000 0.970 0.029
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.000 0.970 0.029
M46.54 Other infective spondylopathies (Thoracic region)
0.000 0.970 0.029
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.000 0.970 0.029
M46.52 Other infective spondylopathies (Cervical region)
0.000 0.970 0.029
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.000 0.970 0.029
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.000 0.970 0.029
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.000 0.970 0.029
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.000 0.970 0.029
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.000 0.970 0.029
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.000 0.970 0.029
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.000 0.970 0.029
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.000 0.970 0.029
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.000 0.970 0.029
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.000 0.970 0.029
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.000 0.970 0.029
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.000 0.970 0.029
D62 Acute posthaemorrhagic anaemia
0.000 0.971 0.029
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.000 0.971 0.029
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.000 0.971 0.029
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.000 0.971 0.029
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.000 0.971 0.029
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.000 0.971 0.029
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.000 0.971 0.029
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.000 0.971 0.029
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.000 0.971 0.029
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.000 0.971 0.029

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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