TreeWAS – Variant ID: rs16907840

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06 Other rheumatoid arthritis	0.896	0.104	0.000
M05-M14 Inflammatory polyarthropathies	0.890	0.110	0.000
M06.9 Rheumatoid arthritis, unspecified	0.875	0.125	0.000
M05 Seropositive rheumatoid arthritis	0.869	0.131	0.000
M06.0 Seronegative rheumatoid arthritis	0.863	0.137	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.833	0.167	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.820	0.180	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.797	0.203	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.786	0.214	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.785	0.215	0.000
M06.4 Inflammatory polyarthropathy	0.782	0.218	0.000
M06.3 Rheumatoid nodule	0.780	0.220	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.774	0.226	0.000
M60-M63 Disorders of muscles	0.763	0.237	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.761	0.239	0.000
M86-M90 Other osteopathies	0.748	0.252	0.000
M62 Other disorders of muscle	0.748	0.252	0.000
M07 Psoriatic and enteropathic arthropathies	0.742	0.258	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.741	0.259	0.000
M05.2 Rheumatoid vasculitis	0.734	0.266	0.000
M62.8 Other specified disorders of muscle	0.728	0.272	0.000
M12 Other specific arthropathies	0.725	0.275	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.720	0.280	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.699	0.301	0.000
M13 Other arthritis	0.698	0.301	0.000
M62.88 Other specified disorders of muscle (Other)	0.698	0.302	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.691	0.309	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.686	0.314	0.000
M05.8 Other seropositive rheumatoid arthritis	0.676	0.324	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.675	0.325	0.000
M08 Juvenile arthritis	0.674	0.326	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.673	0.326	0.000
M86 Osteomyelitis	0.673	0.327	0.000
M50-M54 Other dorsopathies	0.668	0.332	0.000
M90 Osteopathies in diseases classified elsewhere	0.656	0.343	0.000
M00-M03 Infectious arthropathies	0.655	0.345	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.653	0.347	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.647	0.353	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.645	0.355	0.000
M06.8 Other specified rheumatoid arthritis	0.642	0.358	0.000
M06.2 Rheumatoid bursitis	0.642	0.358	0.000
M06.1 Adult-onset Still's disease	0.642	0.358	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.640	0.360	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.638	0.362	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.638	0.362	0.000
M13.0 Polyarthritis, unspecified	0.637	0.363	0.000
M07.3 Other psoriatic arthropathies	0.636	0.364	0.000
M06.34 Rheumatoid nodule (Hand)	0.634	0.366	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.629	0.371	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.627	0.373	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.627	0.373	0.000
M12.3 Palindromic rheumatism	0.625	0.375	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.623	0.377	0.000
M05.1 Rheumatoid lung disease	0.623	0.377	0.000
M05.0 Felty's syndrome	0.623	0.377	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.622	0.378	0.000
M50 Cervical disk disorders	0.621	0.379	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.619	0.381	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.619	0.381	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.619	0.381	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.619	0.381	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.619	0.381	0.000
M14 Arthropathies in other diseases classified elsewhere	0.616	0.384	0.000
M99 Biomechanical lesions, not elsewhere classified	0.615	0.385	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.606	0.394	0.000
M62.9 Disorder of muscle, unspecified	0.602	0.398	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.600	0.400	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.598	0.402	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.597	0.403	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.597	0.403	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.597	0.403	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.597	0.403	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.597	0.403	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.597	0.403	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.595	0.405	0.000
M11 Other crystal arthropathies	0.594	0.405	0.001
M65-M68 Disorders of synovium and tendon	0.592	0.408	0.000
M50.0 Cervical disk disorder with myelopathy	0.590	0.410	0.000
M90.7 Fracture of bone in neoplastic disease	0.589	0.411	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.588	0.412	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.582	0.418	0.000
M87 Osteonecrosis	0.581	0.419	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.579	0.421	0.000
M86.9 Osteomyelitis, unspecified	0.575	0.425	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.565	0.435	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.564	0.436	0.000
M20-M25 Other joint disorders	0.564	0.436	0.000
M86.6 Other chronic osteomyelitis	0.563	0.437	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.561	0.439	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.561	0.439	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.561	0.439	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.561	0.439	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.561	0.439	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.561	0.439	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.561	0.439	0.000
M62.6 Muscle strain	0.559	0.441	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.559	0.441	0.000
M06.38 Rheumatoid nodule (Other)	0.559	0.441	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.559	0.441	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.559	0.441	0.000
M06.33 Rheumatoid nodule (Forearm)	0.559	0.441	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.559	0.441	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.559	0.441	0.000
M89 Other disorders of bone	0.559	0.441	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.559	0.441	0.000
M45-M49 Spondylopathies	0.559	0.441	0.000
M13.8 Other specified arthritis	0.552	0.448	0.000
M50.9 Cervical disk disorder, unspecified	0.552	0.448	0.000
M00 Pyogenic arthritis	0.548	0.452	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.547	0.453	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.547	0.453	0.000
M61 Calcification and ossification of muscle	0.547	0.453	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.546	0.454	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.541	0.459	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.539	0.461	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.539	0.461	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.538	0.462	0.000
M62.4 Contracture of muscle	0.536	0.464	0.000
M62.3 Immobility syndrome (paraplegic)	0.536	0.464	0.000
M62.2 Ischaemic infarction of muscle	0.536	0.464	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.536	0.464	0.000
M62.0 Diastasis of muscle	0.536	0.464	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.533	0.467	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.533	0.467	0.000
M62.84 Other specified disorders of muscle (Hand)	0.532	0.468	0.000
M07.6 Other enteropathic arthropathies	0.532	0.468	0.000
M07.5 Arthropathy in ulcerative colitis	0.532	0.468	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.532	0.468	0.000
M07.2 Psoriatic spondylitis	0.532	0.468	0.000
M07.1 Arthritis mutilans	0.532	0.468	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.532	0.468	0.000
M13.1 Monoarthritis, not elsewhere classified	0.529	0.471	0.000
M05.28 Rheumatoid vasculitis (Other)	0.526	0.473	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.526	0.473	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.526	0.473	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.526	0.473	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.526	0.473	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.526	0.473	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.526	0.473	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.526	0.473	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.525	0.475	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.522	0.478	0.000
M60 Myositis	0.520	0.480	0.000
M08.0 Juvenile rheumatoid arthritis	0.520	0.480	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.519	0.480	0.000
M12.5 Traumatic arthropathy	0.519	0.480	0.000
M12.4 Intermittent hydrarthrosis	0.519	0.480	0.000
M12.1 Kaschin-Beck disease	0.519	0.480	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.519	0.480	0.000
M24 Other specific joint derangements	0.516	0.484	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.507	0.493	0.000
M53 Other dorsopathies, not elsewhere classified	0.506	0.494	0.000
M21 Other acquired deformities of limbs	0.505	0.495	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.503	0.497	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.502	0.498	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.498	0.502	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.496	0.504	0.000
M88 Paget's disease of bone [osteitis deformans]	0.494	0.505	0.000
M02 Reactive arthropathies	0.494	0.506	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.494	0.506	0.000
M22 Disorders of patella	0.493	0.507	0.000
M86.8 Other osteomyelitis	0.493	0.507	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.489	0.511	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.489	0.511	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.485	0.514	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.484	0.515	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.484	0.515	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.484	0.515	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.484	0.515	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.484	0.515	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.484	0.515	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.484	0.515	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.484	0.515	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.484	0.515	0.000
M08.9 Juvenile arthritis, unspecified	0.483	0.516	0.000
M08.8 Other juvenile arthritis	0.483	0.516	0.000
M08.4 Pauciarticular juvenile arthritis	0.483	0.516	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.483	0.516	0.000
M08.2 Juvenile arthritis with systemic onset	0.483	0.516	0.000
M08.1 Juvenile ankylosing spondylitis	0.483	0.516	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.483	0.517	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.483	0.517	0.000
M86.3 Chronic multifocal osteomyelitis	0.483	0.517	0.000
M86.2 Subacute osteomyelitis	0.483	0.517	0.000
M86.1 Other acute osteomyelitis	0.483	0.517	0.000
M86.0 Acute haematogenous osteomyelitis	0.483	0.517	0.000
M50.1 Cervical disk disorder with radiculopathy	0.483	0.517	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.482	0.518	0.000
M31 Other necrotising vasculopathies	0.481	0.519	0.000
M12.2 Villonodular synovitis (pigmented)	0.480	0.520	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.477	0.523	0.000
M89.3 Hypertrophy of bone	0.476	0.524	0.000
M11.8 Other specified crystal arthropathies	0.475	0.524	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.475	0.525	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.474	0.526	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.474	0.526	0.000
M10 Gout	0.472	0.528	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.471	0.529	0.000
M90.6 Osteitis deformans in neoplastic disease	0.471	0.529	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.471	0.529	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.471	0.529	0.000
M90.3 Osteonecrosis in caisson disease	0.471	0.529	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.471	0.529	0.000
M90.0 Tuberculosis of bone	0.471	0.529	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.470	0.530	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.470	0.530	0.000
M66 Spontaneous rupture of synovium and tendon	0.467	0.532	0.000
M87.1 Osteonecrosis due to drugs	0.467	0.533	0.000
M21.0 Valgus deformity, not elsewhere classified	0.466	0.534	0.000
M65 Synovitis and tenosynovitis	0.463	0.537	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.463	0.537	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.462	0.537	0.000
M46 Other inflammatory spondylopathies	0.463	0.537	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.460	0.539	0.000
M06.18 Adult-onset Still's disease (Other)	0.460	0.539	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.460	0.539	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.460	0.539	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.460	0.539	0.000
M06.14 Adult-onset Still's disease (Hand)	0.460	0.539	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.460	0.539	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.460	0.539	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.460	0.539	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.460	0.539	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.460	0.539	0.000
M06.28 Rheumatoid bursitis (Other)	0.460	0.539	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.460	0.539	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.460	0.539	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.460	0.539	0.000
M06.24 Rheumatoid bursitis (Hand)	0.460	0.539	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.460	0.539	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.460	0.539	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.460	0.539	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.460	0.539	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.460	0.539	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.460	0.539	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.460	0.539	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.460	0.539	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.460	0.539	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.460	0.539	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.460	0.539	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.460	0.539	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.460	0.539	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.460	0.539	0.000
M47 Spondylosis	0.460	0.540	0.000
M89.0 Algoneurodystrophy	0.458	0.541	0.000
M50.8 Other cervical disk disorders	0.458	0.542	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.457	0.542	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.457	0.542	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.457	0.542	0.000
M09.0 Juvenile arthritis in psoriasis	0.457	0.542	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.457	0.542	0.000
M96.5 Postradiation scoliosis	0.457	0.542	0.000
M96.4 Postsurgical lordosis	0.457	0.542	0.000
M96.3 Postlaminectomy kyphosis	0.457	0.542	0.000
M96.2 Postradiation kyphosis	0.457	0.542	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.457	0.543	0.000
M13.08 Polyarthritis, unspecified (Other)	0.457	0.543	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.457	0.543	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.457	0.543	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.457	0.543	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.457	0.543	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.457	0.543	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.457	0.543	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.457	0.543	0.000
M34 Systemic sclerosis	0.457	0.543	0.000
M07.38 Other psoriatic arthropathies (Other)	0.456	0.544	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.456	0.544	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.456	0.544	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.456	0.544	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.456	0.544	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.455	0.545	0.000
M00.9 Pyogenic arthritis, unspecified	0.455	0.545	0.000
M12.38 Palindromic rheumatism (Other)	0.448	0.552	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.448	0.552	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.448	0.552	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.448	0.552	0.000
M12.34 Palindromic rheumatism (Hand)	0.448	0.552	0.000
M12.33 Palindromic rheumatism (Forearm)	0.448	0.552	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.448	0.552	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.448	0.552	0.000
M13.89 Other specified arthritis (Site unspecified)	0.447	0.553	0.000
M05.09 Felty's syndrome (Site unspecified)	0.446	0.553	0.000
M05.08 Felty's syndrome (Other)	0.446	0.553	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.446	0.553	0.000
M05.06 Felty's syndrome (Lower leg)	0.446	0.553	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.446	0.553	0.000
M05.04 Felty's syndrome (Hand)	0.446	0.553	0.000
M05.03 Felty's syndrome (Forearm)	0.446	0.553	0.000
M05.02 Felty's syndrome (Upper arm)	0.446	0.553	0.000
M05.01 Felty's syndrome (Shoulder region)	0.446	0.553	0.000
M05.00 Felty's syndrome (Multiple sites)	0.446	0.553	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.446	0.553	0.000
M05.18 Rheumatoid lung disease (Other)	0.446	0.553	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.446	0.553	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.446	0.553	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.446	0.553	0.000
M05.14 Rheumatoid lung disease (Hand)	0.446	0.553	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.446	0.553	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.446	0.553	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.446	0.553	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.446	0.553	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.446	0.553	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.446	0.553	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.446	0.553	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.446	0.553	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.446	0.553	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.446	0.553	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.446	0.553	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.446	0.553	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.446	0.553	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.446	0.553	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.446	0.554	0.000
M40-M43 Deforming dorsopathies	0.446	0.554	0.000
M89.5 Osteolysis	0.445	0.555	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.442	0.558	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.442	0.558	0.000
M14.4 Arthropathy in amyloidosis	0.442	0.558	0.000
M14.3 Lipoid dermatoarthritis	0.442	0.558	0.000
M14.2 Diabetic arthropathy	0.442	0.558	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.442	0.558	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.442	0.558	0.000
M99.9 Biomechanical lesion, unspecified	0.441	0.559	0.000
M99.8 Other biomechanical lesions	0.441	0.559	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.441	0.559	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.441	0.559	0.000
M99.4 Connective tissue stenosis of neural canal	0.441	0.559	0.000
M99.3 Osseous stenosis of neural canal	0.441	0.559	0.000
M99.2 Subluxation stenosis of neural canal	0.441	0.559	0.000
M99.1 Subluxation complex (vertebral)	0.441	0.559	0.000
M99.0 Segmental and somatic dysfunction	0.441	0.559	0.000
M11.9 Crystal arthropathy, unspecified	0.440	0.560	0.001
M91-M94 Chondropathies	0.440	0.560	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.438	0.562	0.000
M24.0 Loose body in joint	0.438	0.562	0.000
M32 Systemic lupus erythematosus	0.438	0.562	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.437	0.563	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.435	0.565	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.431	0.568	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.431	0.568	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.431	0.568	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.431	0.568	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.431	0.568	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.431	0.568	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.431	0.568	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.431	0.568	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.430	0.570	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.427	0.573	0.000
M11.1 Familial chondrocalcinosis	0.426	0.573	0.001
M11.0 Hydroxyapatite deposition disease	0.426	0.573	0.001
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.424	0.576	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.424	0.576	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.422	0.578	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.422	0.578	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.422	0.578	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.422	0.578	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.422	0.578	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.422	0.578	0.000
M54 Dorsalgia	0.422	0.578	0.000
M65.8 Other synovitis and tenosynovitis	0.422	0.578	0.000
M87.8 Other osteonecrosis	0.421	0.579	0.000
M14.6 Neuropathic arthropathy	0.420	0.580	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.419	0.581	0.000
M22.2 Patellofemoral disorders	0.418	0.582	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.416	0.583	0.000
M87.3 Other secondary osteonecrosis	0.416	0.584	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.416	0.584	0.000
M46.4 Discitis, unspecified	0.416	0.584	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.416	0.584	0.000
M87.9 Osteonecrosis, unspecified	0.414	0.586	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.412	0.587	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.412	0.587	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.412	0.587	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.412	0.587	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.412	0.588	0.000
M13.86 Other specified arthritis (Lower leg)	0.411	0.589	0.000
M22.9 Disorder of patella, unspecified	0.409	0.590	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.409	0.591	0.000
M24.5 Contracture of joint	0.409	0.591	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.407	0.593	0.000
M87.2 Osteonecrosis due to previous trauma	0.405	0.595	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.405	0.595	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.405	0.595	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.405	0.595	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.405	0.595	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.405	0.595	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.405	0.595	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.405	0.595	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.405	0.595	0.000
M21.2 Flexion deformity	0.405	0.595	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.405	0.595	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.404	0.596	0.000
M86.68 Other chronic osteomyelitis (Other)	0.404	0.596	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.404	0.596	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.404	0.596	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.404	0.596	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.404	0.596	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.404	0.596	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.404	0.596	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.404	0.596	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.403	0.596	0.000
M62.69 Muscle strain (Site unspecified)	0.401	0.599	0.000
M62.68 Muscle strain (Other)	0.401	0.599	0.000
M62.67 Muscle strain (Ankle and foot)	0.401	0.599	0.000
M62.66 Muscle strain (Lower leg)	0.401	0.599	0.000
M62.64 Muscle strain (Hand)	0.401	0.599	0.000
M62.63 Muscle strain (Forearm)	0.401	0.599	0.000
M62.62 Muscle strain (Upper arm)	0.401	0.599	0.000
M62.61 Muscle strain (Shoulder region)	0.401	0.599	0.000
M62.60 Muscle strain (Multiple sites)	0.401	0.599	0.000
M89.6 Osteopathy after poliomyelitis	0.401	0.599	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.401	0.599	0.000
M89.2 Other disorders of bone development and growth	0.401	0.599	0.000
M89.1 Epiphyseal arrest	0.401	0.599	0.000
M35 Other systemic involvement of connective tissue	0.401	0.599	0.000
M54.2 Cervicalgia	0.401	0.599	0.000
M31.7 Microscopic polyangiitis	0.398	0.602	0.000
M31.1 Thrombotic microangiopathy	0.397	0.603	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.397	0.603	0.000
M13.88 Other specified arthritis (Other)	0.396	0.604	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.396	0.604	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.396	0.604	0.000
M13.84 Other specified arthritis (Hand)	0.396	0.604	0.000
M13.83 Other specified arthritis (Forearm)	0.396	0.604	0.000
M13.82 Other specified arthritis (Upper arm)	0.396	0.604	0.000
M13.81 Other specified arthritis (Shoulder region)	0.396	0.604	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.394	0.606	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.393	0.607	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.393	0.607	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.393	0.607	0.000
M61.9 Calcification and ossification of muscle, unspecified	0.392	0.608	0.000
M61.5 Other ossification of muscle	0.392	0.608	0.000
M61.4 Other calcification of muscle	0.392	0.608	0.000
M61.3 Calcification and ossification of muscles associated with burns	0.392	0.608	0.000
M61.2 Paralytic calcification and ossification of muscle	0.392	0.608	0.000
M61.1 Myositis ossificans progressiva	0.392	0.608	0.000
M61.0 Myositis ossificans traumatica	0.392	0.608	0.000
M63.8 Other disorders of muscle in diseases classified elsewhere	0.392	0.608	0.000
M63.3 Myositis in sarcoidosis	0.392	0.608	0.000
M63.2 Myositis in other infectious diseases classified elsewhere	0.392	0.608	0.000
M63.1 Myositis in protozoal and parasitic infections classified elsewhere	0.392	0.608	0.000
M63.0 Myositis in bacterial diseases classified elsewhere	0.392	0.608	0.000
M21.6 Other acquired deformities of ankle and foot	0.392	0.608	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.392	0.608	0.000
M54.3 Sciatica	0.391	0.609	0.000
M11.86 Other specified crystal arthropathies (Lower leg)	0.390	0.610	0.000
M24.7 Protrusio acetabuli	0.389	0.611	0.000
M24.6 Ankylosis of joint	0.389	0.611	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.387	0.613	0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.387	0.613	0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.387	0.613	0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.387	0.613	0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.387	0.613	0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.387	0.613	0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.387	0.613	0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.387	0.613	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.387	0.613	0.000
M49 Spondylopathies in diseases classified elsewhere	0.385	0.614	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.385	0.615	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.384	0.615	0.000
M62.08 Diastasis of muscle (Other)	0.384	0.615	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.384	0.615	0.000
M62.06 Diastasis of muscle (Lower leg)	0.384	0.615	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.384	0.615	0.000
M62.04 Diastasis of muscle (Hand)	0.384	0.615	0.000
M62.03 Diastasis of muscle (Forearm)	0.384	0.615	0.000
M62.02 Diastasis of muscle (Upper arm)	0.384	0.615	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.384	0.615	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.384	0.615	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.384	0.615	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.384	0.615	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.384	0.615	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.384	0.615	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.384	0.615	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.384	0.615	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.384	0.615	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.384	0.615	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.384	0.615	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.384	0.615	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.384	0.615	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.384	0.615	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.384	0.615	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.384	0.615	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.384	0.615	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.384	0.615	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.384	0.615	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.384	0.615	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.384	0.615	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.384	0.615	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.384	0.615	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.384	0.615	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.384	0.615	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.384	0.615	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.384	0.615	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.384	0.615	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.384	0.615	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.384	0.615	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.384	0.615	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.384	0.615	0.000
M62.49 Contracture of muscle (Site unspecified)	0.384	0.615	0.000
M62.48 Contracture of muscle (Other)	0.384	0.615	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations