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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1690791
log Bayes Factor = 2.86478
Chromosome 1   position 218,645,322  (GRCh37) Explore rs1690791 on Ensembl!
Variant rs1690791 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E04.2 Non-toxic multinodular goitre
0.997 0.003 0.000
E04 Other non-toxic goitre
0.985 0.015 0.000
E00-E07 Disorders of thyroid gland
0.935 0.065 0.000
E03 Other hypothyroidism
0.918 0.082 0.000
E03.9 Hypothyroidism, unspecified
0.899 0.101 0.000
E04.1 Non-toxic single thyroid nodule
0.877 0.123 0.000
E04.0 Non-toxic diffuse goitre
0.842 0.158 0.000
E03.8 Other specified hypothyroidism
0.787 0.213 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.785 0.215 0.000
E06 Thyroiditis
0.769 0.231 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.754 0.246 0.000
E04.9 Non-toxic goitre, unspecified
0.726 0.274 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.715 0.284 0.000
E04.8 Other specified non-toxic goitre
0.706 0.294 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.670 0.330 0.000
E00 Congenital iodine-deficiency syndrome
0.670 0.330 0.000
E03.1 Congenital hypothyroidism without goitre
0.669 0.331 0.000
E03.5 Myxoedema coma
0.658 0.342 0.000
E03.4 Atrophy of thyroid (acquired)
0.658 0.342 0.000
E03.3 Postinfectious hypothyroidism
0.658 0.342 0.000
E06.3 Autoimmune thyroiditis
0.656 0.344 0.000
E05.8 Other thyrotoxicosis
0.649 0.351 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.638 0.362 0.000
E06.9 Thyroiditis, unspecified
0.615 0.385 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.574 0.425 0.000
E05.5 Thyroid crisis or storm
0.563 0.437 0.000
E05.4 Thyrotoxicosis factitia
0.563 0.437 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.563 0.437 0.000
E06.4 Drug-induced thyroiditis
0.551 0.449 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.551 0.449 0.000
E06.0 Acute thyroiditis
0.551 0.449 0.000
E07 Other disorders of thyroid
0.545 0.455 0.000
E06.5 Other chronic thyroiditis
0.535 0.465 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.481 0.519 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.481 0.519 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.481 0.519 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.481 0.519 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.481 0.519 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.481 0.519 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.481 0.519 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.481 0.519 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.481 0.519 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.480 0.520 0.000
E06.1 Subacute thyroiditis
0.466 0.533 0.000
C91 Lymphoid leukaemia
0.466 0.534 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.462 0.538 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.454 0.546 0.000
C91.1 Chronic lymphocytic leukaemia
0.447 0.553 0.000
C90.0 Multiple myeloma
0.446 0.554 0.000
C90.2 Plasmacytoma, extramedullary
0.444 0.556 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.438 0.562 0.000
E07.8 Other specified disorders of thyroid
0.431 0.569 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.428 0.572 0.000
C92 Myeloid leukaemia
0.424 0.576 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.416 0.584 0.000
C90.1 Plasma cell leukaemia
0.415 0.585 0.000
C95 Leukaemia of unspecified cell type
0.406 0.594 0.000
E07.1 Dyshormogenetic goitre
0.391 0.609 0.000
E07.0 Hypersecretion of calcitonin
0.391 0.609 0.000
C92.1 Chronic myeloid leukaemia
0.385 0.615 0.000
C94 Other leukaemias of specified cell type
0.382 0.618 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.376 0.624 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.375 0.625 0.000
C91.9 Lymphoid leukaemia, unspecified
0.374 0.626 0.000
C93 Monocytic leukaemia
0.373 0.627 0.000
C91.5 Adult T-cell leukaemia
0.373 0.627 0.000
C90.3 Solitary plasmacytoma
0.371 0.629 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.353 0.647 0.000
C91.4 Hairy-cell leukaemia
0.351 0.649 0.000
C82.2 Large cell, follicular
0.348 0.652 0.000
C86 Other specified types of T/NK-cell lymphoma
0.347 0.653 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.345 0.655 0.000
C82.4 Follicular lymphoma grade IIIb
0.335 0.665 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.334 0.665 0.000
C91.7 Other lymphoid leukaemia
0.334 0.665 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.334 0.665 0.000
C91.3 Prolymphocytic leukaemia
0.334 0.665 0.000
C91.2 Subacute lymphocytic leukaemia
0.334 0.665 0.000
C82.0 Small cleaved cell, follicular
0.334 0.666 0.000
C95.9 Leukaemia, unspecified
0.333 0.667 0.000
C82.6 Cutaneous follicle centre lymphoma
0.331 0.668 0.000
C82.5 Diffuse follicle centre lymphoma
0.331 0.668 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.330 0.670 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.325 0.675 0.000
C92.5 Acute myelomonocytic leukaemia
0.322 0.678 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.318 0.682 0.000
C88 Malignant immunoproliferative diseases
0.315 0.685 0.000
C85.0 Lymphosarcoma
0.314 0.686 0.000
C82.3 Follicular lymphoma grade IIIa
0.313 0.687 0.000
C94.4 Acute panmyelosis
0.310 0.690 0.000
C92.9 Myeloid leukaemia, unspecified
0.309 0.691 0.000
C92.7 Other myeloid leukaemia
0.306 0.694 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.304 0.696 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.304 0.696 0.000
C92.3 Myeloid sarcoma
0.304 0.696 0.000
C92.2 Subacute myeloid leukaemia
0.304 0.696 0.000
C93.1 Chronic monocytic leukaemia
0.296 0.704 0.000
C91.0 Acute lymphoblastic leukaemia
0.292 0.708 0.000
C92.0 Acute myeloid leukaemia
0.291 0.709 0.000
C95.7 Other leukaemia of unspecified cell type
0.291 0.709 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.291 0.709 0.000
C95.0 Acute leukaemia of unspecified cell type
0.283 0.716 0.000
C92.4 Acute promyelocytic leukaemia
0.279 0.721 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.275 0.724 0.000
C94.7 Other specified leukaemias
0.274 0.726 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.274 0.726 0.000
C94.5 Acute myelofibrosis
0.274 0.726 0.000
C94.3 Mast cell leukaemia
0.274 0.726 0.000
C94.2 Acute megakaryoblastic leukaemia
0.274 0.726 0.000
C94.1 Chronic erythraemia
0.274 0.726 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.274 0.726 0.000
C84.5 Other and unspecified T-cell lymphomas
0.268 0.732 0.000
C93.9 Monocytic leukaemia, unspecified
0.268 0.732 0.000
C93.7 Other monocytic leukaemia
0.268 0.732 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.268 0.732 0.000
C93.2 Subacute monocytic leukaemia
0.268 0.732 0.000
C93.0 Acute monocytic leukaemia
0.268 0.732 0.000
E05.9 Thyrotoxicosis, unspecified
0.260 0.740 0.000
C81 Hodgkin's disease
0.256 0.744 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.253 0.746 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.253 0.746 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.253 0.746 0.000
C84.3 Lymphoepithelioid lymphoma
0.253 0.746 0.000
C84.2 T-zone lymphoma
0.253 0.746 0.000
C84.1 Sezary's diease
0.253 0.746 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.251 0.749 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.249 0.751 0.000
C86.4 Blastic NK-cell lymphoma
0.249 0.751 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.249 0.751 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.249 0.751 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.249 0.751 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.249 0.751 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.248 0.752 0.000
C96.8 Histiocytic sarcoma
0.248 0.752 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.248 0.752 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.248 0.752 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.248 0.752 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.248 0.752 0.000
C96.3 True histiocytic lymphoma
0.248 0.752 0.000
C96.2 Malignant mast cell tumour
0.248 0.752 0.000
C96.1 Malignant histiocytosis
0.248 0.752 0.000
C96.0 Letterer-Siwe disease
0.248 0.752 0.000
C84.4 Peripheral T-cell lymphoma
0.242 0.758 0.000
C85.1 B-cell lymphoma, unspecified
0.235 0.765 0.000
C84.0 Mycosis fungoides
0.229 0.771 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.226 0.774 0.000
C88.7 Other malignant immunoproliferative diseases
0.226 0.774 0.000
C88.3 Immunoproliferative small intestinal disease
0.226 0.774 0.000
C88.2 Gamma heavy chain disease
0.226 0.774 0.000
C88.1 Alpha heavy chain disease
0.226 0.774 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.225 0.775 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.214 0.786 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.210 0.790 0.000
C81.0 Lymphocytic predominance
0.209 0.791 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.183 0.816 0.000
C81.3 Lymphocytic depletion
0.183 0.816 0.000
C81.2 Mixed cellularity
0.168 0.832 0.000
E07.9 Disorder of thyroid, unspecified
0.165 0.835 0.000
K86 Other diseases of pancreas
0.157 0.843 0.000
C81.7 Other Hodgkin's disease
0.155 0.845 0.000
C81.1 Nodular sclerosis
0.154 0.846 0.000
K86.2 Cyst of pancreas
0.153 0.847 0.000
K86.1 Other chronic pancreatitis
0.152 0.848 0.000
C81.9 Hodgkin's disease, unspecified
0.151 0.848 0.000
K86.8 Other specified diseases of pancreas
0.142 0.858 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.142 0.858 0.000
K86.9 Disease of pancreas, unspecified
0.137 0.863 0.000
K86.3 Pseudocyst of pancreas
0.113 0.886 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.069 0.930 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.053 0.946 0.000
C83.7 Burkitt's tumour
0.053 0.947 0.000
C83.6 Undifferentiated (diffuse)
0.050 0.950 0.000
C83.5 Lymphoblastic (diffuse)
0.050 0.950 0.000
C83.4 Immunoblastic (diffuse)
0.050 0.950 0.000
C83.2 Mixed small and large cell (diffuse)
0.050 0.950 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.037 0.963 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.036 0.963 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.035 0.965 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.035 0.965 0.000
N00-N08 Glomerular diseases
0.031 0.969 0.000
N02 Recurrent and persistent haematuria
0.031 0.969 0.000
C83.1 Small cleaved cell (diffuse)
0.030 0.970 0.001
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.030 0.970 0.000
N02.8 Other
0.030 0.970 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.029 0.971 0.000
C83.0 Small cell (diffuse)
0.028 0.972 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.026 0.974 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.026 0.974 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.026 0.974 0.000
N02.2 Diffuse membranous glomerulonephritis
0.025 0.975 0.000
N02.1 Focal and segmental glomerular lesions
0.025 0.975 0.000
N05 Unspecified nephritic syndrome
0.025 0.975 0.000
N02.9 Unspecified
0.024 0.976 0.000
N03 Chronic nephritic syndrome
0.024 0.976 0.000
N02.0 Minor glomerular abnormality
0.023 0.976 0.000
N00 Acute nephritic syndrome
0.023 0.977 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.022 0.978 0.000
N06 Isolated proteinuria with specified morphological lesion
0.022 0.978 0.000
N01 Rapidly progressive nephritic syndrome
0.022 0.978 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.022 0.978 0.000
N02.6 Dense deposit disease
0.022 0.978 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.022 0.978 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.022 0.978 0.000
N05.9 Unspecified
0.022 0.978 0.000
N05.2 Diffuse membranous glomerulonephritis
0.021 0.979 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.020 0.980 0.000
N03.1 Focal and segmental glomerular lesions
0.019 0.981 0.000
N05.8 Other
0.018 0.982 0.000
N03.8 Other
0.018 0.982 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.018 0.982 0.000
N00.9 Unspecified
0.018 0.982 0.000
N05.6 Dense deposit disease
0.018 0.982 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.018 0.982 0.000
N05.0 Minor glomerular abnormality
0.018 0.982 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.018 0.982 0.000
N03.2 Diffuse membranous glomerulonephritis
0.018 0.982 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.017 0.983 0.000
N03.6 Dense deposit disease
0.017 0.983 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.017 0.983 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.017 0.983 0.000
N03.0 Minor glomerular abnormality
0.017 0.983 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.017 0.983 0.000
N00.8 Other
0.017 0.983 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.017 0.983 0.000
N00.6 Dense deposit disease
0.017 0.983 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.017 0.983 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.017 0.983 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.017 0.983 0.000
N00.2 Diffuse membranous glomerulonephritis
0.017 0.983 0.000
N00.1 Focal and segmental glomerular lesions
0.017 0.983 0.000
N00.0 Minor glomerular abnormality
0.017 0.983 0.000
N04 Nephrotic syndrome
0.017 0.983 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.016 0.984 0.000
N01.9 Unspecified
0.016 0.984 0.000
N01.8 Other
0.016 0.984 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.016 0.984 0.000
N01.6 Dense deposit disease
0.016 0.984 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.016 0.984 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.016 0.984 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.016 0.984 0.000
N01.2 Diffuse membranous glomerulonephritis
0.016 0.984 0.000
N01.1 Focal and segmental glomerular lesions
0.016 0.984 0.000
N01.0 Minor glomerular abnormality
0.016 0.984 0.000
N06.9 Unspecified
0.016 0.984 0.000
N06.8 Other
0.016 0.984 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.016 0.984 0.000
N06.6 Dense deposit disease
0.016 0.984 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.016 0.984 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.016 0.984 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.016 0.984 0.000
N06.2 Diffuse membranous glomerulonephritis
0.016 0.984 0.000
N06.1 Focal and segmental glomerular lesions
0.016 0.984 0.000
N06.0 Minor glomerular abnormality
0.016 0.984 0.000
N07.9 Unspecified
0.016 0.984 0.000
N07.8 Other
0.016 0.984 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.016 0.984 0.000
N07.6 Dense deposit disease
0.016 0.984 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.016 0.984 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.016 0.984 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.016 0.984 0.000
N07.2 Diffuse membranous glomerulonephritis
0.016 0.984 0.000
N07.1 Focal and segmental glomerular lesions
0.016 0.984 0.000
N07.0 Minor glomerular abnormality
0.016 0.984 0.000
E89.0 Postprocedural hypothyroidism
0.016 0.984 0.000
N04.0 Minor glomerular abnormality
0.013 0.987 0.000
N03.9 Unspecified
0.013 0.987 0.000
N04.2 Diffuse membranous glomerulonephritis
0.012 0.988 0.000
N04.8 Other
0.012 0.988 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.012 0.988 0.000
N04.6 Dense deposit disease
0.012 0.988 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.012 0.988 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.012 0.988 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.012 0.988 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.988 0.012
Chapter IV Endocrine, nutritional and metabolic diseases
0.011 0.989 0.000
N05.1 Focal and segmental glomerular lesions
0.009 0.990 0.001
C83.3 Large cell (diffuse)
0.010 0.990 0.000
N04.1 Focal and segmental glomerular lesions
0.009 0.990 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.990 0.010
K09.9 Cyst of oral region, unspecified
0.008 0.992 0.000
J43.9 Emphysema, unspecified
0.008 0.992 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.008 0.992 0.000
K09 Cysts of oral region, not elsewhere classified
0.008 0.992 0.000
N04.9 Unspecified
0.008 0.992 0.000
R40.2 Coma, unspecified
0.008 0.992 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.008 0.992 0.000
E50-E64 Other nutritional deficiencies
0.008 0.992 0.000
R13 Dysphagia
0.007 0.993 0.000
M07.3 Other psoriatic arthropathies
0.000 0.993 0.007
E40-E46 Malnutrition
0.007 0.993 0.000
E89.1 Postprocedural hypoinsulinaemia
0.007 0.993 0.000
K09.2 Other cysts of jaw
0.007 0.993 0.000
C77.5 Intrapelvic lymph nodes
0.000 0.993 0.007
C78.7 Secondary malignant neoplasm of liver
0.000 0.993 0.007
K09.0 Developmental odontogenic cysts
0.007 0.993 0.000
R68.8 Other specified general symptoms and signs
0.000 0.993 0.007
K09.1 Developmental (nonodontogenic) cysts of oral region
0.007 0.993 0.000
E61.2 Magnesium deficiency
0.007 0.993 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.993 0.007
T84.2 Mechanical complication of internal fixation device of other bones
0.007 0.993 0.000
E61 Deficiency of other nutrient elements
0.007 0.993 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.006 0.994 0.000
E51 Thiamine deficiency
0.006 0.994 0.000
E65-E68 Obesity and other hyperalimentation
0.006 0.994 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.994 0.006
E63 Other nutritional deficiencies
0.006 0.994 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.006 0.994 0.000
E89.4 Postprocedural ovarian failure
0.006 0.994 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.994 0.006
E89.5 Postprocedural testicular hypofunction
0.006 0.994 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.006 0.994 0.000
E54 Ascorbic acid deficiency
0.006 0.994 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.994 0.006
I34.1 Mitral (valve) prolapse
0.000 0.994 0.006
E64 Sequelae of malnutrition and other nutritional deficiencies
0.006 0.994 0.000
E50 Vitamin A deficiency
0.006 0.994 0.000
E60 Dietary zinc deficiency
0.006 0.994 0.000
E59 Dietary selenium deficiency
0.006 0.994 0.000
E52 Niacin deficiency [pellagra]
0.006 0.994 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.006 0.994 0.000
E65 Localised adiposity
0.006 0.994 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.994 0.005
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.994 0.005
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.994 0.005
E56 Other vitamin deficiencies
0.005 0.994 0.000
E51.2 Wernicke's encephalopathy
0.005 0.994 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.005 0.994 0.000
E45 Retarded development following protein-energy malnutrition
0.005 0.994 0.000
E43 Unspecified severe protein-energy malnutrition
0.005 0.994 0.000
E42 Marasmic kwashiorkor
0.005 0.994 0.000
E41 Nutritional marasmus
0.005 0.994 0.000
E40 Kwashiorkor
0.005 0.994 0.000
O20.8 Other haemorrhage in early pregnancy
0.005 0.995 0.000
C78.0 Secondary malignant neoplasm of lung
0.000 0.995 0.005
R40 Somnolence, stupor and coma
0.005 0.995 0.000
E63.9 Nutritional deficiency, unspecified
0.005 0.995 0.000
D47.4 Osteomyelofibrosis
0.005 0.995 0.000
E58 Dietary calcium deficiency
0.005 0.995 0.000
E89.3 Postprocedural hypopituitarism
0.005 0.995 0.000
E53 Deficiency of other B group vitamins
0.005 0.995 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.005 0.995 0.000
E61.9 Deficiency of nutrient element, unspecified
0.005 0.995 0.000
E61.8 Deficiency of other specified nutrient elements
0.005 0.995 0.000
E61.7 Deficiency of multiple nutrient elements
0.005 0.995 0.000
E61.6 Vanadium deficiency
0.005 0.995 0.000
E61.5 Molybdenum deficiency
0.005 0.995 0.000
E61.4 Chromium deficiency
0.005 0.995 0.000
E61.3 Manganese deficiency
0.005 0.995 0.000
E61.0 Copper deficiency
0.005 0.995 0.000
E46 Unspecified protein-energy malnutrition
0.005 0.995 0.000
E51.9 Thiamine deficiency, unspecified
0.005 0.995 0.000
E51.8 Other manifestations of thiamine deficiency
0.005 0.995 0.000
E51.1 Beriberi
0.005 0.995 0.000
E67 Other hyperalimentation
0.005 0.995 0.000
E68 Sequelae of hyperalimentation
0.005 0.995 0.000
R40.1 Stupor
0.005 0.995 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.005 0.995 0.000
E63.8 Other specified nutritional deficiencies
0.004 0.995 0.000
E63.1 Imbalance of constituents of food intake
0.004 0.995 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.004 0.995 0.000
K75.8 Other specified inflammatory liver diseases
0.005 0.995 0.000
R40.0 Somnolence
0.005 0.995 0.000
E70-E90 Metabolic disorders
0.005 0.995 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.995 0.004
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.995 0.004
E88 Other metabolic disorders
0.004 0.995 0.000
E15 Nondiabetic hypoglycaemic coma
0.004 0.996 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.004 0.996 0.000
I38 Endocarditis, valve unspecified
0.000 0.996 0.004
E88.2 Lipomatosis, not elsewhere classified
0.004 0.996 0.000
E86 Volume depletion
0.004 0.996 0.000
E50.9 Vitamin A deficiency, unspecified
0.004 0.996 0.000
E50.8 Other manifestations of vitamin A deficiency
0.004 0.996 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.004 0.996 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.004 0.996 0.000
E50.5 Vitamin A deficiency with night blindness
0.004 0.996 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.004 0.996 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.004 0.996 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.004 0.996 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.004 0.996 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.004 0.996 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.004 0.996 0.000
E64.8 Sequelae of other nutritional deficiencies
0.004 0.996 0.000
E64.3 Sequelae of rickets
0.004 0.996 0.000
E64.2 Sequelae of vitamin C deficiency
0.004 0.996 0.000
E64.1 Sequelae of vitamin A deficiency
0.004 0.996 0.000
E64.0 Sequelae of protein-energy malnutrition
0.004 0.996 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.004 0.996 0.000
E56.9 Vitamin deficiency, unspecified
0.004 0.996 0.000
E56.8 Deficiency of other vitamins
0.004 0.996 0.000
E56.0 Deficiency of vitamin E
0.004 0.996 0.000
E44.1 Mild protein-energy malnutrition
0.004 0.996 0.000
E44.0 Moderate protein-energy malnutrition
0.004 0.996 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.996 0.004
E56.1 Deficiency of vitamin K
0.004 0.996 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.996 0.004
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.996 0.004
E53.1 Pyridoxine deficiency
0.004 0.996 0.000
E53.0 Riboflavin deficiency
0.004 0.996 0.000
E55 Vitamin D deficiency
0.004 0.996 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.004 0.996 0.000
L85.9 Epidermal thickening, unspecified
0.004 0.996 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.004 0.996 0.000
E53.9 Vitamin B deficiency, unspecified
0.004 0.996 0.000
E67.8 Other specified hyperalimentation
0.003 0.996 0.000
E67.3 Hypervitaminosis D
0.003 0.996 0.000
E67.2 Megavitamin-B6 syndrome
0.003 0.996 0.000
E67.1 Hypercarotenaemia
0.003 0.996 0.000
E67.0 Hypervitaminosis A
0.003 0.996 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.996 0.004
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.004 0.996 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.004 0.996 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.004 0.996 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.003 0.996 0.000
E77 Disorders of glycoprotein metabolism
0.003 0.996 0.000
E76 Disorders of glycosaminoglycan metabolism
0.003 0.996 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.996 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.996 0.000
E79 Disorders of purine and pyrimidine metabolism
0.003 0.996 0.000
E72 Other disorders of amino-acid metabolism
0.003 0.996 0.000
E74 Other disorders of carbohydrate metabolism
0.003 0.996 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.997 0.003
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.003 0.997 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.997 0.003
E88.9 Metabolic disorder, unspecified
0.003 0.997 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.997 0.003
W19.2 School, other institution and public administrative area
0.003 0.997 0.000
E84 Cystic fibrosis
0.003 0.997 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.997 0.000
E70 Disorders of aromatic amino-acid metabolism
0.003 0.997 0.000
E89.2 Postprocedural hypoparathyroidism
0.003 0.997 0.000
D47.2 Monoclonal gammopathy
0.003 0.997 0.000
E53.8 Deficiency of other specified B group vitamins
0.003 0.997 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.997 0.003
J33.8 Other polyp of sinus
0.000 0.997 0.003
E88.3 Tumour lysis syndrome
0.003 0.997 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.997 0.003
I34 Nonrheumatic mitral valve disorders
0.000 0.997 0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.000 0.997 0.003
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.997 0.003
C44.4 Skin of scalp and neck
0.003 0.997 0.000
D47.1 Chronic myeloproliferative disease
0.003 0.997 0.000
E55.0 Rickets, active
0.003 0.997 0.000
K75 Other inflammatory liver diseases
0.003 0.997 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.997 0.000
D44.0 Thyroid gland
0.003 0.997 0.000
K60.1 Chronic anal fissure
0.003 0.997 0.000
D44.3 Pituitary gland
0.003 0.997 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.003 0.997 0.000
I05.0 Mitral stenosis
0.000 0.997 0.003
S42.30 Fracture of shaft of humerus (closed)
0.000 0.997 0.003
E71.3 Disorders of fatty-acid metabolism
0.003 0.997 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.997 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.997 0.000
E71.0 Maple-syrup-urine disease
0.003 0.997 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.997 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.997 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.997 0.000
E76.2 Other mucopolysaccharidoses
0.003 0.997 0.000
E76.1 Mucopolysaccharidosis, type II
0.003 0.997 0.000
E76.0 Mucopolysaccharidosis, type I
0.003 0.997 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.997 0.000
E77.8 Other disorders of glycoprotein metabolism
0.003 0.997 0.000
E77.1 Defects in glycoprotein degradation
0.003 0.997 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.997 0.000
M07.6 Other enteropathic arthropathies
0.000 0.997 0.003
K75.9 Inflammatory liver disease, unspecified
0.003 0.997 0.000
K75.4 Autoimmune hepatitis
0.003 0.997 0.000
D46 Myelodysplastic syndromes
0.003 0.997 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.997 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.997 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.997 0.000
E72.5 Disorders of glycine metabolism
0.003 0.997 0.000
E72.4 Disorders of ornithine metabolism
0.003 0.997 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.997 0.000
E72.2 Disorders of urea cycle metabolism
0.003 0.997 0.000
E72.0 Disorders of amino-acid transport
0.003 0.997 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.997 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.997 0.000
E79.1 Lesch-Nyhan syndrome
0.003 0.997 0.000
E74.0 Glycogen storage disease
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.003 0.997 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.003 0.997 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.003 0.997 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.003 0.997 0.000
E74.2 Disorders of galactose metabolism
0.003 0.997 0.000
E74.1 Disorders of fructose metabolism
0.003 0.997 0.000
E75.2 Other sphingolipidosis
0.003 0.997 0.000
D44.4 Craniopharyngeal duct
0.003 0.997 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.003 0.997 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.000 0.997 0.003
M96.4 Postsurgical lordosis
0.000 0.997 0.003
M96.3 Postlaminectomy kyphosis
0.000 0.997 0.003
M96.2 Postradiation kyphosis
0.000 0.997 0.003
E73 Lactose intolerance
0.002 0.997 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.997 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.997 0.003
E80.6 Other disorders of bilirubin metabolism
0.003 0.997 0.000
M07.5 Arthropathy in ulcerative colitis
0.000 0.997 0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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