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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16919333
log Bayes Factor = 7.20476
Chromosome 9   position 103,452,327  (GRCh37) Explore rs16919333 on Ensembl!
Variant rs16919333 is part of Cluster X0218

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M25 Other joint disorders, not elsewhere classified
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.993 0.007 0.000
O00-O08 Pregnancy with abortive outcome
0.991 0.009 0.000
M40-M43 Deforming dorsopathies
0.985 0.015 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.979 0.021 0.000
M41 Scoliosis
0.979 0.021 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.978 0.022 0.000
M41.9 Scoliosis, unspecified
0.975 0.025 0.000
O04 Medical abortion
0.974 0.026 0.000
M23 Internal derangement of knee
0.969 0.031 0.000
O04.9 Complete or unspecified, without complication
0.967 0.033 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.966 0.034 0.000
M25.3 Other instability of joint
0.964 0.036 0.000
M35.0 Sicca syndrome [Sjogren]
0.961 0.039 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.955 0.045 0.000
M25.7 Osteophyte
0.954 0.046 0.000
M23.8 Other internal derangements of knee
0.948 0.052 0.000
M15-M19 Arthrosis
0.947 0.053 0.000
M17 Gonarthrosis [arthrosis of knee]
0.946 0.054 0.000
M86-M90 Other osteopathies
0.944 0.056 0.000
M25.8 Other specified joint disorders
0.941 0.059 0.000
M17.9 Gonarthrosis, unspecified
0.931 0.069 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.931 0.069 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.928 0.072 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.927 0.073 0.000
M25.37 Other instability of joint (Ankle and foot)
0.927 0.073 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.920 0.080 0.000
O26.9 Pregnancy-related condition, unspecified
0.919 0.081 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.917 0.083 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.910 0.090 0.000
M35.7 Hypermobility syndrome
0.906 0.094 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.905 0.095 0.000
M17.1 Other primary gonarthrosis
0.887 0.113 0.000
O03 Spontaneous abortion
0.884 0.116 0.000
O20 Haemorrhage in early pregnancy
0.884 0.116 0.000
O41 Other disorders of amniotic fluid and membranes
0.883 0.117 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.877 0.123 0.000
M25.78 Osteophyte (Other)
0.877 0.123 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.875 0.125 0.000
O26.8 Other specified pregnancy-related conditions
0.870 0.130 0.000
M89 Other disorders of bone
0.870 0.130 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.864 0.136 0.000
M25.0 Haemarthrosis
0.855 0.145 0.000
O63 Long labour
0.855 0.145 0.000
M23.0 Cystic meniscus
0.854 0.146 0.000
M25.83 Other specified joint disorders (Forearm)
0.854 0.146 0.000
O85-O92 Complications predominantly related to the puerperium
0.852 0.148 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.851 0.149 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.848 0.152 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.845 0.155 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.844 0.156 0.000
O02 Other abnormal products of conception
0.842 0.158 0.000
O21 Excessive vomiting in pregnancy
0.840 0.160 0.000
O20.0 Threatened abortion
0.836 0.164 0.000
M25.86 Other specified joint disorders (Lower leg)
0.832 0.168 0.000
M17.0 Primary gonarthrosis, bilateral
0.827 0.173 0.000
O36 Maternal care for other known or suspected foetal problems
0.826 0.174 0.000
O16 Unspecified maternal hypertension
0.825 0.175 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.821 0.179 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.821 0.179 0.000
O42 Premature rupture of membranes
0.819 0.181 0.000
O26.2 Pregnancy care of habitual aborter
0.814 0.186 0.000
M23.3 Other meniscus derangements
0.814 0.186 0.000
M25.5 Pain in joint
0.812 0.188 0.000
M40 Kyphosis and lordosis
0.812 0.188 0.000
M35.3 Polymyalgia rheumatica
0.810 0.190 0.000
O40 Polyhydramnios
0.809 0.191 0.000
M90 Osteopathies in diseases classified elsewhere
0.808 0.192 0.000
O61 Failed induction of labour
0.806 0.194 0.000
M35.1 Other overlap syndromes
0.806 0.194 0.000
M21 Other acquired deformities of limbs
0.804 0.196 0.000
O72 Postpartum haemorrhage
0.801 0.199 0.000
M25.31 Other instability of joint (Shoulder region)
0.800 0.200 0.000
O22 Venous complications in pregnancy
0.795 0.205 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.795 0.205 0.000
O34.3 Maternal care for cervical incompetence
0.795 0.205 0.000
O48 Prolonged pregnancy
0.791 0.209 0.000
O32.2 Maternal care for transverse and oblique lie
0.787 0.213 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.785 0.215 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.781 0.219 0.000
M25.74 Osteophyte (Hand)
0.778 0.222 0.000
M31 Other necrotising vasculopathies
0.775 0.225 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.774 0.226 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.770 0.229 0.000
M60-M63 Disorders of muscles
0.770 0.230 0.000
O30 Multiple gestation
0.770 0.230 0.000
O41.0 Oligohydramnios
0.770 0.230 0.000
M95.0 Acquired deformity of nose
0.765 0.235 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.761 0.239 0.000
O45 Premature separation of placenta [abruptio placentae]
0.761 0.239 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.760 0.240 0.000
O33 Maternal care for known or suspected disproportion
0.759 0.241 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.755 0.245 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.755 0.245 0.000
M25.06 Haemarthrosis (Lower leg)
0.752 0.248 0.000
M86 Osteomyelitis
0.750 0.250 0.000
M25.53 Pain in joint (Forearm)
0.749 0.251 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.747 0.253 0.000
M17.5 Other secondary gonarthrosis
0.744 0.256 0.000
O63.0 Prolonged first stage (of labour)
0.743 0.257 0.000
M25.9 Joint disorder, unspecified
0.741 0.259 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.740 0.260 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.739 0.261 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.737 0.263 0.000
M23.1 Discoid meniscus (congenital)
0.735 0.265 0.000
M25.84 Other specified joint disorders (Hand)
0.734 0.266 0.000
O72.1 Other immediate postpartum haemorrhage
0.734 0.266 0.000
O14.9 Preeclampsia, unspecified
0.733 0.267 0.000
O03.3 Incomplete, with other and unspecified complications
0.732 0.268 0.000
M30 Polyarteritis nodosa and related conditions
0.732 0.268 0.000
M89.9 Disorder of bone, unspecified
0.731 0.269 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.729 0.271 0.000
M25.76 Osteophyte (Lower leg)
0.727 0.273 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.726 0.274 0.000
M89.8 Other specified disorders of bone
0.725 0.275 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.723 0.277 0.000
M25.88 Other specified joint disorders (Other)
0.721 0.279 0.000
O02.1 Missed abortion
0.720 0.280 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.283 0.000
M41.8 Other forms of scoliosis
0.716 0.283 0.000
M25.2 Flail joint
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
O31 Complications specific to multiple gestation
0.716 0.284 0.000
M15 Polyarthrosis
0.716 0.284 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.714 0.286 0.000
O14.0 Moderate preeclampsia
0.713 0.287 0.000
O29 Complications of anaesthesia during pregnancy
0.712 0.287 0.000
O25 Malnutrition in pregnancy
0.712 0.287 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.712 0.288 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.712 0.288 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.712 0.288 0.000
M35.8 Other specified systemic involvement of connective tissue
0.712 0.288 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.712 0.288 0.000
M35.5 Multifocal fibrosclerosis
0.712 0.288 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.712 0.288 0.000
M35.2 Behcet's disease
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M90.7 Fracture of bone in neoplastic disease
0.711 0.289 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.711 0.289 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.711 0.289 0.000
O07 Failed attempted abortion
0.711 0.289 0.000
O06 Unspecified abortion
0.711 0.289 0.000
O05 Other abortion
0.711 0.289 0.000
O01 Hydatidiform mole
0.711 0.289 0.000
O21.9 Vomiting of pregnancy, unspecified
0.711 0.289 0.000
M42 Spinal osteochondrosis
0.706 0.294 0.000
O64.1 Obstructed labour due to breech presentation
0.706 0.294 0.000
M80-M85 Disorders of bone density and structure
0.705 0.295 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
O14.1 Severe preeclampsia
0.704 0.296 0.000
O32.0 Maternal care for unstable lie
0.703 0.297 0.000
O32.4 Maternal care for high head at term
0.703 0.297 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.702 0.298 0.000
O34.6 Maternal care for abnormality of vagina
0.702 0.298 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.702 0.298 0.000
O34.4 Maternal care for other abnormalities of cervix
0.702 0.298 0.000
O34.0 Maternal care for congenital malformation of uterus
0.702 0.298 0.000
M41.5 Other secondary scoliosis
0.702 0.298 0.000
M41.4 Neuromuscular scoliosis
0.702 0.298 0.000
M41.3 Thoracogenic scoliosis
0.702 0.298 0.000
M41.2 Other idiopathic scoliosis
0.702 0.298 0.000
M41.1 Juvenile idiopathic scoliosis
0.702 0.298 0.000
M41.0 Infantile idiopathic scoliosis
0.702 0.298 0.000
M99 Biomechanical lesions, not elsewhere classified
0.702 0.298 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.701 0.298 0.000
O26.5 Maternal hypotension syndrome
0.701 0.298 0.000
O26.4 Herpes gestationis
0.701 0.298 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.701 0.298 0.000
O26.1 Low weight gain in pregnancy
0.701 0.298 0.000
O26.0 Excessive weight gain in pregnancy
0.701 0.298 0.000
O36.8 Maternal care for other specified foetal problems
0.701 0.299 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.699 0.301 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.699 0.301 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.699 0.301 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.699 0.301 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.699 0.301 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.699 0.301 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.699 0.301 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.698 0.302 0.000
O04.7 Complete or unspecified, complicated by embolism
0.698 0.302 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.698 0.302 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.698 0.302 0.000
O04.3 Incomplete, with other and unspecified complications
0.698 0.302 0.000
O04.2 Incomplete, complicated by embolism
0.698 0.302 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.698 0.302 0.000
O90 Complications of the puerperium, not elsewhere classified
0.698 0.302 0.000
O73 Retained placenta and membranes, without haemorrhage
0.695 0.304 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.694 0.306 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.693 0.307 0.000
O15 Eclampsia
0.692 0.308 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.692 0.308 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.692 0.308 0.000
M25.39 Other instability of joint (Site unspecified)
0.691 0.309 0.000
M25.38 Other instability of joint (Other)
0.691 0.309 0.000
M25.36 Other instability of joint (Lower leg)
0.691 0.309 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.691 0.309 0.000
M25.33 Other instability of joint (Forearm)
0.691 0.309 0.000
M25.32 Other instability of joint (Upper arm)
0.691 0.309 0.000
M25.30 Other instability of joint (Multiple sites)
0.691 0.309 0.000
M40.2 Other and unspecified kyphosis
0.687 0.313 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.687 0.313 0.000
M23.9 Internal derangement of knee, unspecified
0.686 0.314 0.000
M25.79 Osteophyte (Site unspecified)
0.684 0.316 0.000
M25.73 Osteophyte (Forearm)
0.684 0.316 0.000
M25.70 Osteophyte (Multiple sites)
0.684 0.316 0.000
O03.9 Complete or unspecified, without complication
0.681 0.319 0.000
O66 Other obstructed labour
0.681 0.319 0.000
O24 Diabetes mellitus in pregnancy
0.680 0.320 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.680 0.320 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.680 0.320 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.680 0.320 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.680 0.320 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.680 0.320 0.000
M21.0 Valgus deformity, not elsewhere classified
0.679 0.321 0.000
O28 Abnormal findings on antenatal screening of mother
0.679 0.321 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.678 0.322 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.678 0.322 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.678 0.322 0.000
M89.3 Hypertrophy of bone
0.678 0.322 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.678 0.322 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.677 0.323 0.000
O20.8 Other haemorrhage in early pregnancy
0.676 0.324 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.675 0.325 0.000
M25.82 Other specified joint disorders (Upper arm)
0.675 0.325 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.675 0.325 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.675 0.325 0.000
M05-M14 Inflammatory polyarthropathies
0.674 0.326 0.000
M88 Paget's disease of bone [osteitis deformans]
0.674 0.326 0.000
M89.0 Algoneurodystrophy
0.674 0.326 0.000
M95.2 Other acquired deformity of head
0.672 0.328 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.669 0.331 0.000
O71 Other obstetric trauma
0.669 0.331 0.000
O69.8 Labour and delivery complicated by other cord complications
0.665 0.335 0.000
O63.1 Prolonged second stage (of labour)
0.662 0.338 0.000
M25.51 Pain in joint (Shoulder region)
0.660 0.340 0.000
M23.5 Chronic instability of knee
0.660 0.340 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.660 0.340 0.000
M25.72 Osteophyte (Upper arm)
0.659 0.341 0.000
M21.3 Wrist or foot drop (acquired)
0.658 0.342 0.000
O32.6 Maternal care for compound presentation
0.657 0.343 0.000
O32.3 Maternal care for face, brow and chin presentation
0.657 0.343 0.000
O22.4 Haemorrhoids in pregnancy
0.653 0.347 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.653 0.347 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.653 0.347 0.000
O69.3 Labour and delivery complicated by short cord
0.653 0.347 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.653 0.347 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.652 0.347 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.651 0.349 0.000
M25.34 Other instability of joint (Hand)
0.651 0.349 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.649 0.351 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.649 0.351 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.649 0.351 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.649 0.351 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.649 0.351 0.000
O34.1 Maternal care for tumour of corpus uteri
0.649 0.351 0.000
O61.9 Failed induction of labour, unspecified
0.649 0.351 0.000
M25.71 Osteophyte (Shoulder region)
0.648 0.351 0.000
M95.4 Acquired deformity of chest and rib
0.648 0.352 0.000
M22 Disorders of patella
0.646 0.354 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.646 0.354 0.000
O44 Placenta praevia
0.645 0.355 0.000
O86 Other puerperal infections
0.644 0.356 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.643 0.357 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.643 0.357 0.000
M23.4 Loose body in knee
0.641 0.359 0.000
O03.4 Incomplete, without complication
0.637 0.363 0.000
M31.6 Other giant cell arteritis
0.635 0.365 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.634 0.366 0.000
O03.7 Complete or unspecified, complicated by embolism
0.634 0.366 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.634 0.366 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.634 0.366 0.000
O03.2 Incomplete, complicated by embolism
0.634 0.366 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.634 0.366 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.634 0.366 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.633 0.367 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.633 0.367 0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.633 0.367 0.000
O41.1 Infection of amniotic sac and membranes
0.633 0.367 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.632 0.368 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.630 0.369 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.630 0.370 0.000
O14.2 HELLP syndrome
0.627 0.372 0.000
O80-O84 Delivery
0.626 0.374 0.000
O36.9 Maternal care for foetal problem, unspecified
0.626 0.374 0.000
M89.6 Osteopathy after poliomyelitis
0.624 0.376 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.624 0.376 0.000
M89.2 Other disorders of bone development and growth
0.624 0.376 0.000
M89.1 Epiphyseal arrest
0.624 0.376 0.000
O61.0 Failed medical induction of labour
0.623 0.377 0.000
O87 Venous complications in the puerperium
0.620 0.380 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.619 0.381 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.614 0.386 0.000
M89.5 Osteolysis
0.614 0.386 0.000
M86.6 Other chronic osteomyelitis
0.613 0.387 0.000
M25.09 Haemarthrosis (Site unspecified)
0.613 0.387 0.000
M25.08 Haemarthrosis (Other)
0.613 0.387 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.613 0.387 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.613 0.387 0.000
M25.04 Haemarthrosis (Hand)
0.613 0.387 0.000
M25.03 Haemarthrosis (Forearm)
0.613 0.387 0.000
M25.02 Haemarthrosis (Upper arm)
0.613 0.387 0.000
M25.01 Haemarthrosis (Shoulder region)
0.613 0.387 0.000
M25.00 Haemarthrosis (Multiple sites)
0.613 0.387 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.613 0.387 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.612 0.388 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.612 0.388 0.000
M23.07 Cystic meniscus-Capsular lig
0.612 0.388 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.612 0.388 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.612 0.388 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.612 0.388 0.000
M23.00 Cystic meniscus (Multiple sites)
0.612 0.388 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.612 0.388 0.000
O91 Infections of breast associated with childbirth
0.611 0.389 0.000
O89 Complications of anaesthesia during the puerperium
0.611 0.389 0.000
O88 Obstetric embolism
0.611 0.389 0.000
O85 Puerperal sepsis
0.611 0.389 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.610 0.390 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.610 0.390 0.000
O64.5 Obstructed labour due to compound presentation
0.610 0.390 0.000
O64.4 Obstructed labour due to shoulder presentation
0.610 0.390 0.000
O64.3 Obstructed labour due to brow presentation
0.610 0.390 0.000
O64.2 Obstructed labour due to face presentation
0.610 0.390 0.000
M62 Other disorders of muscle
0.610 0.390 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.608 0.392 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.608 0.392 0.000
M95.5 Acquired deformity of pelvis
0.608 0.392 0.000
M95.3 Acquired deformity of neck
0.608 0.392 0.000
M95.1 Cauliflower ear
0.608 0.392 0.000
O21.0 Mild hyperemesis gravidarum
0.608 0.392 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.608 0.392 0.000
M89.88 Other specified disorders of bone (Other)
0.608 0.392 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.608 0.392 0.000
O30.0 Twin pregnancy
0.606 0.394 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.606 0.394 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.606 0.394 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.606 0.394 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.606 0.394 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.606 0.394 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.606 0.394 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.606 0.394 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.606 0.394 0.000
O63.9 Long labour, unspecified
0.605 0.395 0.000
O32.1 Maternal care for breech presentation
0.605 0.395 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.605 0.395 0.000
O02.9 Abnormal product of conception, unspecified
0.603 0.396 0.000
O02.8 Other specified abnormal products of conception
0.603 0.396 0.000
O21.8 Other vomiting complicating pregnancy
0.602 0.397 0.000
O21.2 Late vomiting of pregnancy
0.602 0.397 0.000
M25.50 Pain in joint (Multiple sites)
0.601 0.398 0.000
O12.1 Gestational proteinuria
0.601 0.399 0.000
M25.59 Pain in joint (Site unspecified)
0.599 0.401 0.000
M87 Osteonecrosis
0.593 0.406 0.000
M21.4 Flat foot [pes planus] (acquired)
0.593 0.407 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.592 0.408 0.000
O36.4 Maternal care for intra-uterine death
0.592 0.408 0.000
O36.2 Maternal care for hydrops foetalis
0.592 0.408 0.000
O36.1 Maternal care for other isoimmunisation
0.592 0.408 0.000
O45.9 Premature separation of placenta, unspecified
0.591 0.409 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.591 0.409 0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.590 0.410 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.588 0.412 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.587 0.413 0.000
O33.9 Maternal care for disproportion, unspecified
0.587 0.413 0.000
M91-M94 Chondropathies
0.586 0.413 0.000
M14 Arthropathies in other diseases classified elsewhere
0.585 0.415 0.000
M17.3 Other posttraumatic gonarthrosis
0.584 0.416 0.000
M23.37 Other meniscus derangements-Capsular lig
0.583 0.416 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.582 0.417 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.583 0.417 0.000
M40.5 Lordosis, unspecified
0.582 0.418 0.000
M40.4 Other lordosis
0.582 0.418 0.000
M40.3 Flatback syndrome
0.582 0.418 0.000
M40.1 Other secondary kyphosis
0.582 0.418 0.000
M40.0 Postural kyphosis
0.582 0.418 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.579 0.420 0.000
M90.6 Osteitis deformans in neoplastic disease
0.579 0.420 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.579 0.420 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.579 0.420 0.000
M90.3 Osteonecrosis in caisson disease
0.579 0.420 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.579 0.420 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.579 0.420 0.000
M90.0 Tuberculosis of bone
0.579 0.420 0.000
O61.8 Other failed induction of labour
0.578 0.422 0.000
O61.1 Failed instrumental induction of labour
0.578 0.422 0.000
O04.4 Incomplete, without complication
0.578 0.422 0.000
M85 Other disorders of bone density and structure
0.577 0.423 0.000
M21.9 Acquired deformity of limb, unspecified
0.577 0.423 0.000
M21.8 Other specified acquired deformities of limbs
0.577 0.423 0.000
M21.7 Unequal limb length (acquired)
0.577 0.423 0.000
M22.2 Patellofemoral disorders
0.576 0.424 0.000
O23 Infections of genito-urinary tract in pregnancy
0.575 0.424 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.575 0.425 0.000
O72.3 Postpartum coagulation defects
0.574 0.426 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.571 0.429 0.000
O22.9 Venous complication in pregnancy, unspecified
0.570 0.430 0.000
O22.8 Other venous complications in pregnancy
0.570 0.430 0.000
O22.5 Cerebral venous thrombosis in pregnancy
0.570 0.430 0.000
O22.3 Deep phlebothrombosis in pregnancy
0.570 0.430 0.000
O22.2 Superficial thrombophlebitis in pregnancy
0.570 0.430 0.000
O22.1 Genital varices in pregnancy
0.570 0.430 0.000
O22.0 Varicose veins of lower extremity in pregnancy
0.570 0.430 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.568 0.432 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.567 0.433 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.567 0.433 0.000
O12.0 Gestational oedema
0.565 0.435 0.000
M25.58 Pain in joint (Other)
0.558 0.441 0.000
M40.24 Other and unspecified kyphosis (Thoracic region)
0.558 0.442 0.000
M43 Other deforming dorsopathies
0.556 0.443 0.000
M31.9 Necrotising vasculopathy, unspecified
0.555 0.444 0.000
M31.8 Other specified necrotising vasculopathies
0.555 0.444 0.000
M31.7 Microscopic polyangiitis
0.555 0.444 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.555 0.444 0.000
M31.2 Lethal midline granuloma
0.555 0.444 0.000
M31.1 Thrombotic microangiopathy
0.555 0.444 0.000
M31.0 Hypersensitivity angiitis
0.555 0.444 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.553 0.446 0.000
M40.29 Other and unspecified kyphosis (Site unspecified)
0.553 0.446 0.000
O67.8 Other intrapartum haemorrhage
0.552 0.447 0.000
O67.0 Intrapartum haemorrhage with coagulation defect
0.552 0.447 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.552 0.448 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.552 0.448 0.000
M61 Calcification and ossification of muscle
0.552 0.448 0.000
M60 Myositis
0.552 0.448 0.000
O30.9 Multiple gestation, unspecified
0.552 0.448 0.000
O30.8 Other multiple gestation
0.552 0.448 0.000
O30.2 Quadruplet pregnancy
0.552 0.448 0.000
O30.1 Triplet pregnancy
0.552 0.448 0.000
M15.1 Heberden's nodes (with arthropathy)
0.550 0.450 0.000
M25.77 Osteophyte (Ankle and foot)
0.549 0.450 0.000
M25.57 Pain in joint (Ankle and foot)
0.547 0.453 0.000
O12.2 Gestational oedema with proteinuria
0.546 0.454 0.000
O45.8 Other premature separation of placenta
0.546 0.454 0.000
O45.0 Premature separation of placenta with coagulation defect
0.546 0.454 0.000
M25.4 Effusion of joint
0.546 0.454 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.545 0.455 0.000
O33.8 Maternal care for disproportion of other origin
0.544 0.456 0.000
O33.7 Maternal care for disproportion due to other foetal deformities
0.544 0.456 0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus
0.544 0.456 0.000
O33.5 Maternal care for disproportion due to unusually large foetus
0.544 0.456 0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin
0.544 0.456 0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis
0.544 0.456 0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis
0.544 0.456 0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis
0.544 0.456 0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones
0.544 0.456 0.000
M21.6 Other acquired deformities of ankle and foot
0.543 0.457 0.000
O71.8 Other specified obstetric trauma
0.541 0.459 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.541 0.459 0.000
M30.0 Polyarteritis nodosa
0.541 0.459 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.541 0.459 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.540 0.460 0.000
M86.8 Other osteomyelitis
0.538 0.462 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.538 0.462 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.538 0.462 0.000
M86.3 Chronic multifocal osteomyelitis
0.538 0.462 0.000
M86.2 Subacute osteomyelitis
0.538 0.462 0.000
M86.1 Other acute osteomyelitis
0.538 0.462 0.000
M86.0 Acute haematogenous osteomyelitis
0.538 0.462 0.000
O90.2 Haematoma of obstetric wound
0.536 0.464 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.536 0.464 0.000
M86.9 Osteomyelitis, unspecified
0.535 0.464 0.000
M21.1 Varus deformity, not elsewhere classified
0.535 0.464 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.535 0.465 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.535 0.465 0.000
O62 Abnormalities of forces of labour
0.534 0.466 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.534 0.466 0.000
M25.52 Pain in joint (Upper arm)
0.533 0.467 0.000
M21.2 Flexion deformity
0.533 0.467 0.000
M89.04 Algoneurodystrophy (Hand)
0.533 0.467 0.000
M25.56 Pain in joint (Lower leg)
0.532 0.468 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.531 0.468 0.000
M25.98 Joint disorder, unspecified (Other)
0.531 0.468 0.000
M25.94 Joint disorder, unspecified (Hand)
0.531 0.468 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.531 0.468 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.531 0.468 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.531 0.468 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.531 0.468 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.531 0.469 0.000
O90.9 Complication of the puerperium, unspecified
0.531 0.469 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.530 0.470 0.000
O90.1 Disruption of perineal obstetric wound
0.529 0.470 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.528 0.472 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.527 0.473 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.527 0.473 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.527 0.473 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.527 0.473 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.527 0.473 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.527 0.473 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.527 0.473 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.527 0.473 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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