TreeWAS – Variant ID: rs16937456

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.20 Fracture of shaft of tibia (closed)	0.038	0.962	0.000
S82.2 Fracture of shaft of tibia	0.037	0.962	0.000
S82 Fracture of lower leg, including ankle	0.037	0.963	0.000
S82.3 Fracture of lower end of tibia	0.037	0.963	0.000
S82.30 Fracture of lower end of tibia (closed)	0.036	0.964	0.000
Z95.2 Presence of prosthetic heart valve	0.035	0.965	0.000
S82.1 Fracture of upper end of tibia	0.032	0.968	0.000
H83.0 Labyrinthitis	0.000	0.969	0.031
S80-S89 Injuries to the knee and lower leg	0.031	0.969	0.000
S82.4 Fracture of fibula alone	0.031	0.969	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.030	0.970	0.000
S82.21 Fracture of shaft of tibia (open)	0.029	0.970	0.000
S82.31 Fracture of lower end of tibia (open)	0.029	0.971	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.029	0.971	0.000
S82.10 Fracture of upper end of tibia (closed)	0.029	0.971	0.000
S80 Superficial injury of lower leg	0.028	0.972	0.000
S82.5 Fracture of medial malleolus	0.027	0.973	0.000
S82.9 Fracture of lower leg, part unspecified	0.027	0.973	0.000
S82.7 Multiple fractures of lower leg	0.027	0.973	0.000
S82.40 Fracture of fibula alone (closed)	0.026	0.974	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.026	0.974	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.026	0.974	0.000
S83.7 Injury to multiple structures of knee	0.026	0.974	0.000
S86 Injury of muscle and tendon at lower leg level	0.026	0.974	0.000
S82.0 Fracture of patella	0.024	0.976	0.000
S82.11 Fracture of upper end of tibia (open)	0.024	0.976	0.000
S83.3 Tear of articular cartilage of knee, current	0.024	0.976	0.000
S80.8 Other superficial injuries of lower leg	0.023	0.977	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.023	0.977	0.000
S88 Traumatic amputation of lower leg	0.022	0.978	0.000
S87 Crushing injury of lower leg	0.022	0.978	0.000
S85 Injury of blood vessels at lower leg level	0.022	0.978	0.000
S84 Injury of nerves at lower leg level	0.022	0.978	0.000
S82.41 Fracture of fibula alone (open)	0.022	0.978	0.000
S80.9 Superficial injury of lower leg, unspecified	0.022	0.978	0.000
I35.0 Aortic (valve) stenosis	0.021	0.979	0.000
S83.1 Dislocation of knee	0.021	0.979	0.000
S83.0 Dislocation of patella	0.021	0.979	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.021	0.979	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.021	0.979	0.000
S82.8 Fractures of other parts of lower leg	0.021	0.979	0.000
S80.7 Multiple superficial injuries of lower leg	0.020	0.980	0.000
S82.50 Fracture of medial malleolus (closed)	0.020	0.980	0.000
S82.51 Fracture of medial malleolus (open)	0.020	0.980	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.020	0.980	0.000
S82.71 Multiple fractures of lower leg (open)	0.019	0.980	0.000
S82.70 Multiple fractures of lower leg (closed)	0.019	0.980	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.019	0.980	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.019	0.980	0.000
I26 Pulmonary embolism	0.019	0.981	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.019	0.981	0.000
S89 Other and unspecified injuries of lower leg	0.019	0.981	0.000
I35 Nonrheumatic aortic valve disorders	0.019	0.981	0.000
S86.0 Injury of Achilles tendon	0.018	0.981	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.018	0.981	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.018	0.981	0.000
I35.8 Other aortic valve disorders	0.018	0.982	0.000
S82.6 Fracture of lateral malleolus	0.017	0.982	0.000
S82.81 Fractures of other parts of lower leg (open)	0.017	0.983	0.000
I35.1 Aortic (valve) insufficiency	0.017	0.983	0.000
S82.01 Fracture of patella (open)	0.017	0.983	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.016	0.983	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.016	0.984	0.000
S84.8 Injury of other nerves at lower leg level	0.016	0.984	0.000
S84.7 Injury of multiple nerves at lower leg level	0.016	0.984	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.016	0.984	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.016	0.984	0.000
S84.0 Injury of tibial nerve at lower leg level	0.016	0.984	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.016	0.984	0.000
S85.8 Injury of other blood vessels at lower leg level	0.016	0.984	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.016	0.984	0.000
S85.5 Injury of popliteal vein	0.016	0.984	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.016	0.984	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.016	0.984	0.000
S85.2 Injury of peroneal artery	0.016	0.984	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.016	0.984	0.000
S85.0 Injury of popliteal artery	0.016	0.984	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.016	0.984	0.000
S87.0 Crushing injury of knee	0.016	0.984	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.016	0.984	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.016	0.984	0.000
S88.0 Traumatic amputation at knee level	0.016	0.984	0.000
S82.00 Fracture of patella (closed)	0.016	0.984	0.000
S83.2 Tear of meniscus, current	0.015	0.985	0.000
S82.86 Maisonneuve's fracture	0.015	0.985	0.000
S80.0 Contusion of knee	0.014	0.986	0.000
H83 Other diseases of inner ear	0.000	0.986	0.014
S89.8 Other specified injuries of lower leg	0.014	0.986	0.000
S89.7 Multiple injuries of lower leg	0.014	0.986	0.000
S89.1 Other specified injuries of lower leg	0.014	0.986	0.000
S89.0 Multiple injuries of lower leg	0.014	0.986	0.000
S86.00 Unspecified injury of Achilles tendon	0.013	0.986	0.000
S81 Open wound of lower leg	0.013	0.986	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.014	0.986	0.000
I35.9 Aortic valve disorder, unspecified	0.013	0.987	0.000
S82.61 Fracture of lateral malleolus (open)	0.013	0.987	0.000
I27.0 Primary pulmonary hypertension	0.013	0.987	0.000
I27 Other pulmonary heart diseases	0.013	0.987	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.012	0.988	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.011	0.989	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.989	0.010
H83.8 Other specified diseases of inner ear	0.000	0.989	0.010
H83.3 Noise effects on inner ear	0.000	0.989	0.010
H83.2 Labyrinthine dysfunction	0.000	0.989	0.010
H83.1 Labyrinthine fistula	0.000	0.989	0.010
S89.9 Unspecified injury of lower leg	0.010	0.990	0.000
S81.7 Multiple open wounds of lower leg	0.010	0.990	0.000
I28 Other diseases of pulmonary vessels	0.010	0.990	0.000
I27.8 Other specified pulmonary heart diseases	0.009	0.990	0.000
I27.1 Kyphoscoliotic heart disease	0.009	0.991	0.000
I27.9 Pulmonary heart disease, unspecified	0.009	0.991	0.000
S81.8 Open wound of other parts of lower leg	0.009	0.991	0.000
K29.0 Acute haemorrhagic gastritis	0.009	0.991	0.000
I27.2 Other secondary pulmonary hypertension	0.009	0.991	0.000
R87.6 Abnormal cytological findings	0.000	0.992	0.008
S81.9 Open wound of lower leg, part unspecified	0.008	0.992	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.007	0.993	0.000
I28.1 Aneurysm of pulmonary artery	0.007	0.993	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.007	0.993	0.000
I28.8 Other specified diseases of pulmonary vessels	0.007	0.993	0.000
S81.0 Open wound of knee	0.007	0.993	0.000
T92 Sequelae of injuries of upper limb	0.007	0.993	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.006	0.994	0.000
T92.1 Sequelae of fracture of arm	0.006	0.994	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.006	0.994	0.000
T92.0 Sequelae of open wound of upper limb	0.006	0.994	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.006	0.994	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.005	0.995	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.995	0.005
T93 Sequelae of injuries of lower limb	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
E61.1 Iron deficiency	0.005	0.995	0.000
I95.9 Hypotension, unspecified	0.005	0.995	0.000
C20 Malignant neoplasm of rectum	0.005	0.995	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.005	0.995	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.005	0.995	0.000
T93.0 Sequelae of open wound of lower limb	0.005	0.995	0.000
I51.7 Cardiomegaly	0.005	0.995	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
I45.1 Other and unspecified right bundle-branch block	0.005	0.995	0.000
T95 Sequelae of burns, corrosions and frostbite	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
T90 Sequelae of injuries of head	0.005	0.995	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.005	0.995	0.000
I45 Other conduction disorders	0.004	0.996	0.000
I45.9 Conduction disorder, unspecified	0.004	0.996	0.000
R87 Abnormal findings in specimens from female genital organs	0.000	0.996	0.004
T40.4 Other synthetic narcotics	0.004	0.996	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.004	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.004	0.996	0.000
T93.1 Sequelae of fracture of femur	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.004	0.996	0.000
I31.3 Pericardial effusion (noninflammatory)	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.004	0.996	0.000
H01.0 Blepharitis	0.004	0.996	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T90.1 Sequelae of open wound of head	0.004	0.996	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.004	0.996	0.000
T21 Burn and corrosion of trunk	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
I45.5 Other specified heart block	0.004	0.996	0.000
T21.0 Burn of unspecified degree of trunk	0.004	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.004	0.996	0.000
I31 Other diseases of pericardium	0.004	0.996	0.000
T90.5 Sequelae of intracranial injury	0.004	0.996	0.000
Z04.8 Examination and observation for other specified reasons	0.004	0.996	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.004	0.996	0.000
I45.6 Preexcitation syndrome	0.004	0.996	0.000
R87.7 Abnormal histological findings	0.000	0.996	0.004
T94.1 Sequelae of injuries, not specified by body region	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.004	0.996	0.000
I30-I52 Other forms of heart disease	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
T90.8 Sequelae of other specified injuries of head	0.004	0.996	0.000
S40 Superficial injury of shoulder and upper arm	0.004	0.996	0.000
I51 Complications and ill-defined descriptions of heart disease	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.003	0.996	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.003	0.996	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.003	0.996	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.003	0.996	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.003	0.996	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.003	0.996	0.000
I95 Hypotension	0.004	0.996	0.000
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.004	0.996	0.000
T21.2 Burn of second degree of trunk	0.003	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.996	0.000
T40.8 Lysergide [LSD]	0.003	0.996	0.000
T40.7 Cannabis (derivatives)	0.003	0.996	0.000
T40.5 Cocaine	0.003	0.996	0.000
T40.3 Methadone	0.003	0.996	0.000
T40.1 Heroin	0.003	0.996	0.000
T40.0 Opium	0.003	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.003	0.996	0.000
T90.3 Sequelae of injury of cranial nerves	0.003	0.996	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.996	0.000
I45.3 Trifascicular block	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
I45.0 Right fascicular block	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
I95.0 Idiopathic hypotension	0.003	0.997	0.000
N87.0 Mild cervical dysplasia	0.000	0.997	0.003
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
K63.9 Disease of intestine, unspecified	0.000	0.997	0.003
R87.8 Other abnormal findings	0.000	0.997	0.003
R87.5 Abnormal microbiological findings	0.000	0.997	0.003
R87.4 Abnormal immunological findings	0.000	0.997	0.003
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.997	0.003
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.997	0.003
R87.1 Abnormal level of hormones	0.000	0.997	0.003
R87.0 Abnormal level of enzymes	0.000	0.997	0.003
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
Y85.0 Sequelae of motor-vehicle accident	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.003	0.997	0.000
I37 Pulmonary valve disorders	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
I45.4 Nonspecific intraventricular block	0.003	0.997	0.000
I51.4 Myocarditis, unspecified	0.003	0.997	0.000
T21.3 Burn of third degree of trunk	0.003	0.997	0.000
T91.3 Sequelae of injury of spinal cord	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.003	0.997	0.000
T21.6 Corrosion of second degree of trunk	0.003	0.997	0.000
T21.5 Corrosion of first degree of trunk	0.003	0.997	0.000
T21.4 Corrosion of unspecified degree of trunk	0.003	0.997	0.000
T21.1 Burn of first degree of trunk	0.003	0.997	0.000
Y84.6 Urinary catheterisation	0.003	0.997	0.000
I45.8 Other specified conduction disorders	0.003	0.997	0.000
S40.0 Contusion of shoulder and upper arm	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
R87.9 Unspecified abnormal finding	0.000	0.997	0.003
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
I31.8 Other specified diseases of pericardium	0.003	0.997	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.997	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.997	0.000
I31.0 Chronic adhesive pericarditis	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
Y84.0 Cardiac catheterisation	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.003	0.997	0.000
I48 Atrial fibrillation and flutter	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
I41 Myocarditis in diseases classified elsewhere	0.003	0.997	0.000
I40 Acute myocarditis	0.003	0.997	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I32 Pericarditis in diseases classified elsewhere	0.003	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T09 Other injuries of spine and trunk, level unspecified	0.003	0.997	0.000
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
I51.5 Myocardial degeneration	0.003	0.997	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.003	0.997	0.000
Y85 Sequelae of transport accidents	0.003	0.997	0.000
I37.1 Pulmonary valve insufficiency	0.003	0.997	0.000
T33-T35 Frostbite	0.003	0.997	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.997	0.000
I51.6 Cardiovascular disease, unspecified	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
I30 Acute pericarditis	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.003	0.997	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.997	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.997	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
I33 Acute and subacute endocarditis	0.003	0.997	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
K50.9 Crohn's disease, unspecified	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T47.2 Stimulant laxatives	0.002	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
T37.5 Antiviral drugs	0.002	0.997	0.000
T37.4 Anthelminthics	0.002	0.997	0.000
T37.3 Other antiprotozoal drugs	0.002	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
T37.1 Antimycobacterial drugs	0.002	0.997	0.000
T37.0 Sulphonamides	0.002	0.997	0.000
T41.5 Therapeutic gases	0.002	0.997	0.000
T41.4 Anaesthetic, unspecified	0.002	0.997	0.000
T41.3 Local anaesthetics	0.002	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
T41.1 Intravenous anaesthetics	0.002	0.997	0.000
T41.0 Inhaled anaesthetics	0.002	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
T48.5 Anti-common-cold drugs	0.002	0.997	0.000
T48.4 Expectorants	0.002	0.997	0.000
T48.3 Antitussives	0.002	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
T48.0 Oxytocic drugs	0.002	0.997	0.000
T49.9 Topical agent, unspecified	0.002	0.997	0.000
T49.8 Other topical agents	0.002	0.997	0.000
T49.7 Dental drugs, topically applied	0.002	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.997	0.000
T49.2 Local astringents and local detergents	0.002	0.997	0.000
T49.1 Antipruritics	0.002	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T38.7 Androgens and anabolic congeners	0.002	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
T38.4 Oral contraceptives	0.002	0.997	0.000
T38.2 Antithyroid drugs	0.002	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.997	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.997	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.997	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.997	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.997	0.000
T09.3 Injury of spinal cord, level unspecified	0.003	0.997	0.000
T09.0 Superficial injury of trunk, level unspecified	0.003	0.997	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.002	0.997	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
I95.8 Other hypotension	0.002	0.997	0.000
I95.2 Hypotension due to drugs	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
I37.9 Pulmonary valve disorder, unspecified	0.002	0.997	0.000
I37.8 Other pulmonary valve disorders	0.002	0.997	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.002	0.997	0.000
I37.0 Pulmonary valve stenosis	0.002	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.997	0.000
T44.0 Anticholinesterase agents	0.002	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.997	0.000
J39.8 Other specified diseases of upper respiratory tract	0.003	0.997	0.000
S90.0 Contusion of ankle	0.002	0.997	0.000
T01 Open wounds involving multiple body regions	0.002	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y84.2 Radiological procedure and radiotherapy	0.003	0.997	0.000
M88.9 Paget's disease of bone, unspecified	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.997	0.000
T36.8 Other systemic antibiotics	0.002	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
T36.6 Rifamycins	0.002	0.997	0.000
T36.5 Aminoglycosides	0.002	0.997	0.000
T36.4 Tetracyclines	0.002	0.997	0.000
T36.3 Macrolides	0.002	0.997	0.000
T36.2 Chloramphenicol group	0.002	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.002	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.002	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.002	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.002	0.997	0.000
S20-S29 Injuries to the thorax	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.997	0.000
T42.3 Barbiturates	0.002	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.997	0.000
T42.1 Iminostilbenes	0.002	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.997	0.000
H80-H83 Diseases of inner ear	0.000	0.997	0.002
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.997	0.000
T11.1 Open wound of upper limb, level unspecified	0.002	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.997	0.000
Y84.4 Aspiration of fluid	0.002	0.997	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
I45.2 Bifascicular block	0.002	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.002	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.002	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.002	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.002	0.998	0.000
T25.3 Burn of third degree of ankle and foot	0.002	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.998	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.998	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.998	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.998	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.998	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.998	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations