TreeWAS – Variant ID: rs16966142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44 Other malignant neoplasms of skin	0.000	0.373	0.627
C44.5 Skin of trunk	0.000	0.382	0.618
C44.7 Skin of lower limb, including hip	0.000	0.388	0.612
C44.3 Skin of other and unspecified parts of face	0.000	0.424	0.576
C44.4 Skin of scalp and neck	0.000	0.431	0.569
C44.0 Skin of lip	0.000	0.441	0.559
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.519	0.481
C44.1 Skin of eyelid, including canthus	0.000	0.533	0.467
C44.2 Skin of ear and external auricular canal	0.000	0.537	0.463
C44.8 Overlapping lesion of skin	0.000	0.550	0.450
C44.6 Skin of upper limb, including shoulder	0.000	0.629	0.371
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.663	0.337
C43 Malignant melanoma of skin	0.000	0.721	0.279
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.768	0.232
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.775	0.225
C43.9 Malignant melanoma of skin, unspecified	0.000	0.775	0.225
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.798	0.202
C43.8 Overlapping malignant melanoma of skin	0.000	0.800	0.200
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.800	0.200
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.800	0.200
C43.0 Malignant melanoma of lip	0.000	0.800	0.200
C43.4 Malignant melanoma of scalp and neck	0.000	0.832	0.168
C43.5 Malignant melanoma of trunk	0.000	0.833	0.167
R52.1 Chronic intractable pain	0.020	0.980	0.000
Z13.9 Special screening examination, unspecified	0.000	0.989	0.011
O16 Unspecified maternal hypertension	0.010	0.990	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.992	0.008
H26.4 After-cataract	0.008	0.992	0.000
N62 Hypertrophy of breast	0.008	0.992	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.993	0.007
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.993	0.007
D12.4 Descending colon	0.006	0.994	0.000
D12.2 Ascending colon	0.006	0.994	0.000
J18.1 Lobar pneumonia, unspecified	0.005	0.995	0.000
H26 Other cataract	0.005	0.995	0.000
J90 Pleural effusion, not elsewhere classified	0.005	0.995	0.000
C15.4 Middle third of oesophagus	0.005	0.995	0.000
H26.2 Complicated cataract	0.005	0.995	0.000
C15.9 Oesophagus, unspecified	0.005	0.995	0.000
O26.8 Other specified pregnancy-related conditions	0.005	0.995	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.005	0.995	0.000
C15 Malignant neoplasm of oesophagus	0.005	0.995	0.000
C15.5 Lower third of oesophagus	0.005	0.995	0.000
H26.8 Other specified cataract	0.004	0.996	0.000
D12.6 Colon, unspecified	0.004	0.996	0.000
H26.0 Infantile, juvenile and presenile cataract	0.004	0.996	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
R52 Pain, not elsewhere classified	0.004	0.996	0.000
H26.3 Drug-induced cataract	0.004	0.996	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.996	0.004
N48.6 Balanitis xerotica obliterans	0.000	0.996	0.004
H26.1 Traumatic cataract	0.004	0.996	0.000
D12.1 Appendix	0.004	0.996	0.000
D12.0 Caecum	0.004	0.996	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.004	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.004	0.996	0.000
C15.3 Upper third of oesophagus	0.004	0.996	0.000
C15.2 Abdominal part of oesophagus	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
R52.9 Pain, unspecified	0.004	0.996	0.000
J98.1 Pulmonary collapse	0.004	0.996	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.996	0.003
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.997	0.003
D12.9 Anus and anal canal	0.003	0.997	0.000
H27.0 Aphakia	0.003	0.997	0.000
D12.7 Rectosigmoid junction	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.997	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.997	0.003
J18 Pneumonia, organism unspecified	0.003	0.997	0.000
M81.9 Osteoporosis, unspecified	0.003	0.997	0.000
H27 Other disorders of lens	0.003	0.997	0.000
D12.3 Transverse colon	0.003	0.997	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.997	0.003
M81.99 Osteoporosis, unspecified (Site unspecified)	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
H27.8 Other specified disorders of lens	0.003	0.997	0.000
D12.5 Sigmoid colon	0.003	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.003	0.997	0.000
O15 Eclampsia	0.003	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.003	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.003	0.997	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.997	0.003
J92.0 Pleural plaque with presence of asbestos	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.997	0.003
O32.1 Maternal care for breech presentation	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
H27.1 Dislocation of lens	0.003	0.997	0.000
J18.8 Other pneumonia, organism unspecified	0.002	0.997	0.000
J18.2 Hypostatic pneumonia, unspecified	0.002	0.997	0.000
O12.1 Gestational proteinuria	0.002	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.002
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.997	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.002	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.002	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.997	0.000
H27.9 Disorder of lens, unspecified	0.002	0.997	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.997	0.003
I95.2 Hypotension due to drugs	0.000	0.997	0.003
O14.0 Moderate preeclampsia	0.002	0.997	0.000
H25-H28 Disorders of lens	0.003	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
M84 Disorders of continuity of bone	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.000	0.997	0.003
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
J18.9 Pneumonia, unspecified	0.002	0.998	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
J90-J94 Other diseases of pleura	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
O14.2 HELLP syndrome	0.002	0.998	0.000
J92 Pleural plaque	0.002	0.998	0.000
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
D12.8 Rectum	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
N42.0 Calculus of prostate	0.000	0.998	0.002
J09-J18 Influenza and pneumonia	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
N42.2 Atrophy of prostate	0.000	0.998	0.002
F60 Specific personality disorders	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
W19.9 Unspecified place	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
N42 Other disorders of prostate	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
R52.0 Acute pain	0.001	0.998	0.001
J10 Influenza due to identified influenza virus	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
I89.1 Lymphangitis	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
J14 Pneumonia due to Haemophilus influenzae	0.002	0.998	0.000
R52.2 Other chronic pain	0.002	0.998	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
O12.0 Gestational oedema	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
J18.0 Bronchopneumonia, unspecified	0.002	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.002	0.998	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.002	0.998	0.000
J12 Viral pneumonia, not elsewhere classified	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
F60.0 Paranoid personality disorder	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
N42.3 Dysplasia of prostate	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.002	0.998	0.000
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
I42 Cardiomyopathy	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.002	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.002	0.998	0.000
H28.2 Cataract in other diseases classified elsewhere	0.002	0.998	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
H28.0 Diabetic cataract	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.002	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.002	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.002	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.002	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.002	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O26.5 Maternal hypotension syndrome	0.002	0.998	0.000
O26.4 Herpes gestationis	0.002	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.002	0.998	0.000
O26.1 Low weight gain in pregnancy	0.002	0.998	0.000
O26.0 Excessive weight gain in pregnancy	0.002	0.998	0.000
J91 Pleural effusion in conditions classified elsewhere	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.001	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.998	0.000
M83.8 Other adult osteomalacia	0.001	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.998	0.000
M83.4 Aluminum bone disease	0.001	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.998	0.000
M83.1 Senile osteomalacia	0.001	0.998	0.000
M83.0 Puerperal osteomalacia	0.001	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
A40.8 Other streptococcal septicaemia	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.002	0.998	0.000
J11 Influenza, virus not identified	0.001	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
J12.9 Viral pneumonia, unspecified	0.001	0.998	0.000
J12.8 Other viral pneumonia	0.001	0.998	0.000
J12.3 Human metapneumovirus pneumonia	0.001	0.998	0.000
J12.2 Parainfluenza virus pneumonia	0.001	0.998	0.000
J12.1 Respiratory syncytial virus pneumonia	0.001	0.998	0.000
J12.0 Adenoviral pneumonia	0.001	0.998	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.001	0.998	0.000
J16.0 Chlamydial pneumonia	0.001	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.001	0.998	0.000
M85.5 Aneurysmal bone cyst	0.001	0.998	0.000
M85.4 Solitary bone cyst	0.001	0.998	0.000
M85.3 Osteitis condensans	0.001	0.998	0.000
M85.2 Hyperostosis of skull	0.001	0.998	0.000
M85.1 Skeletal fluorosis	0.001	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
J98.6 Disorders of diaphragm	0.002	0.998	0.000
M85.6 Other cyst of bone	0.001	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.998	0.002
J94 Other pleural conditions	0.001	0.998	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.998	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.998	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.998	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.998	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.998	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.998	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.998	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.998	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.001	0.998	0.000
J17.3 Pneumonia in parasitic diseases	0.001	0.998	0.000
J17.2 Pneumonia in mycoses	0.001	0.998	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.001	0.998	0.000
K22.1 Ulcer of oesophagus	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.001	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.001	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.001	0.998	0.000
I42.4 Endocardial fibroelastosis	0.001	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.998	0.000
J86.0 Pyothorax with fistula	0.002	0.998	0.000
N48 Other disorders of penis	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
J98 Other respiratory disorders	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations