TreeWAS – Variant ID: rs170020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K76 Other diseases of liver	0.243	0.757	0.000
K76.8 Other specified diseases of liver	0.236	0.764	0.000
K76.9 Liver disease, unspecified	0.233	0.767	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.229	0.771	0.000
K76.6 Portal hypertension	0.229	0.771	0.000
K76.3 Infarction of liver	0.175	0.825	0.000
K76.5 Hepatic veno-occlusive disease	0.175	0.825	0.000
K76.4 Peliosis hepatis	0.175	0.825	0.000
K76.2 Central haemorrhagic necrosis of liver	0.175	0.825	0.000
K76.7 Hepatorenal syndrome	0.170	0.830	0.000
K74 Fibrosis and cirrhosis of liver	0.162	0.838	0.000
K70-K77 Diseases of liver	0.161	0.839	0.000
K76.1 Chronic passive congestion of liver	0.158	0.842	0.000
K74.6 Other and unspecified cirrhosis of liver	0.149	0.851	0.000
K74.5 Biliary cirrhosis, unspecified	0.149	0.851	0.000
K74.3 Primary biliary cirrhosis	0.140	0.860	0.000
K71 Toxic liver disease	0.123	0.877	0.000
K74.0 Hepatic fibrosis	0.123	0.877	0.000
K77 Liver disorders in diseases classified elsewhere	0.116	0.884	0.000
K74.4 Secondary biliary cirrhosis	0.116	0.884	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.116	0.884	0.000
K74.1 Hepatic sclerosis	0.115	0.885	0.000
K73 Chronic hepatitis, not elsewhere classified	0.114	0.886	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.092	0.908	0.000
K71.9 Toxic liver disease, unspecified	0.091	0.909	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.090	0.910	0.000
K71.0 Toxic liver disease with cholestasis	0.089	0.911	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.088	0.912	0.000
K71.8 Toxic liver disease with other disorders of liver	0.088	0.912	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.088	0.912	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.088	0.912	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.088	0.912	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.088	0.912	0.000
K71.2 Toxic liver disease with acute hepatitis	0.088	0.912	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.087	0.912	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.082	0.918	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.082	0.918	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.080	0.920	0.000
K72 Hepatic failure, not elsewhere classified	0.080	0.920	0.000
K75 Other inflammatory liver diseases	0.080	0.920	0.000
K73.9 Chronic hepatitis, unspecified	0.079	0.921	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.075	0.925	0.000
K75.0 Abscess of liver	0.068	0.932	0.000
K72.1 Chronic hepatic failure	0.060	0.940	0.000
K75.8 Other specified inflammatory liver diseases	0.059	0.941	0.000
K75.2 Nonspecific reactive hepatitis	0.058	0.942	0.000
K75.1 Phlebitis of portal vein	0.058	0.942	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.056	0.943	0.000
K72.0 Acute and subacute hepatic failure	0.047	0.953	0.000
K75.4 Autoimmune hepatitis	0.039	0.961	0.000
K72.9 Hepatic failure, unspecified	0.037	0.963	0.000
K70 Alcoholic liver disease	0.032	0.968	0.000
K70.1 Alcoholic hepatitis	0.025	0.975	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.019	0.980	0.000
K70.4 Alcoholic hepatic failure	0.018	0.981	0.000
K70.9 Alcoholic liver disease, unspecified	0.018	0.982	0.000
K75.9 Inflammatory liver disease, unspecified	0.017	0.983	0.001
K70.3 Alcoholic cirrhosis of liver	0.016	0.984	0.000
D23.3 Skin of other and unspecified parts of face	0.016	0.984	0.000
K70.0 Alcoholic fatty liver	0.014	0.986	0.000
M25.50 Pain in joint (Multiple sites)	0.013	0.987	0.000
T93.2 Sequelae of other fractures of lower limb	0.011	0.989	0.000
E21.0 Primary hyperparathyroidism	0.009	0.991	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.008	0.992	0.000
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
T88.4 Failed or difficult intubation	0.007	0.993	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.993	0.007
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.007	0.993	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.007	0.993	0.000
E21.3 Hyperparathyroidism, unspecified	0.006	0.994	0.000
S83.7 Injury to multiple structures of knee	0.006	0.994	0.000
S83.2 Tear of meniscus, current	0.006	0.994	0.000
O43.1 Malformation of placenta	0.006	0.994	0.000
E11.6 With other specified complications	0.006	0.994	0.000
K50.9 Crohn's disease, unspecified	0.000	0.995	0.005
S83.0 Dislocation of patella	0.005	0.995	0.000
T93 Sequelae of injuries of lower limb	0.005	0.995	0.000
E21.2 Other hyperparathyroidism	0.005	0.995	0.000
I27 Other pulmonary heart diseases	0.005	0.995	0.000
M35.3 Polymyalgia rheumatica	0.005	0.995	0.000
S83.3 Tear of articular cartilage of knee, current	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.995	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.005	0.995	0.000
I27.0 Primary pulmonary hypertension	0.005	0.995	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.005	0.995	0.000
S83.1 Dislocation of knee	0.005	0.995	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.005	0.995	0.000
K07.6 Temporomandibular joint disorders	0.005	0.995	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.995	0.000
I27.9 Pulmonary heart disease, unspecified	0.005	0.995	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.995	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
L60.0 Ingrowing nail	0.004	0.996	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.004	0.996	0.000
Y57.5 X-ray contrast media	0.004	0.996	0.000
C91.1 Chronic lymphocytic leukaemia	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
L60.2 Onychogryphosis	0.004	0.996	0.000
L60 Nail disorders	0.004	0.996	0.000
K50.0 Crohn's disease of small intestine	0.000	0.996	0.004
L60.3 Nail dystrophy	0.004	0.996	0.000
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
L60.1 Onycholysis	0.003	0.997	0.000
B37.4 Candidiasis of other urogenital sites	0.003	0.997	0.000
C32.0 Glottis	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.003	0.997	0.000
L60.4 Beau's lines	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.997	0.000
C32.3 Laryngeal cartilage	0.003	0.997	0.000
C32.1 Supraglottis	0.003	0.997	0.000
J05.1 Acute epiglottitis	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.003	0.997	0.000
L60.8 Other nail disorders	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
K50.8 Other Crohn's disease	0.000	0.997	0.003
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
Z34 Supervision of normal pregnancy	0.000	0.997	0.003
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.003	0.997	0.000
E32 Diseases of thymus	0.002	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.997	0.000
B37.3 Candidiasis of vulva and vagina	0.003	0.997	0.000
M21.2 Flexion deformity	0.002	0.997	0.000
D23.5 Skin of trunk	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.002	0.998	0.000
C32.2 Subglottis	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
E25 Adrenogenital disorders	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
K61.3 Ischiorectal abscess	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
B37 Candidiasis	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
K07.0 Major anomalies of jaw size	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
R06.1 Stridor	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
G54.0 Brachial plexus disorders	0.000	0.998	0.002
B37.1 Pulmonary candidiasis	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
S79.9 Unspecified injury of hip and thigh	0.000	0.998	0.002
D68 Other coagulation defects	0.002	0.998	0.000
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
O43 Placental disorders	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
B37.0 Candidal stomatitis	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
J04.0 Acute laryngitis	0.002	0.998	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.002	0.998	0.000
B37.6 Candidal endocarditis	0.002	0.998	0.000
B37.5 Candidal meningitis	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.998	0.002
Z58.1 Exposure to air pollution	0.000	0.998	0.002
B37.7 Candidal septicaemia	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
D23 Other benign neoplasms of skin	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
E34 Other endocrine disorders	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.998	0.002
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
W49.9 Unspecified place	0.002	0.998	0.000
J94.2 Haemothorax	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
N92.4 Excessive bleeding in the premenopausal period	0.002	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.002	0.998	0.000
I28 Other diseases of pulmonary vessels	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
J98.6 Disorders of diaphragm	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
K07.5 Dentofacial functional abnormalities	0.002	0.998	0.000
Z93.3 Colostomy status	0.002	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
R84.9 Unspecified abnormal finding	0.002	0.998	0.000
R84.6 Abnormal cytological findings	0.002	0.998	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
D23.0 Skin of lip	0.002	0.998	0.000
K07.8 Other dentofacial anomalies	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
R84.7 Abnormal histological findings	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
M96.5 Postradiation scoliosis	0.002	0.998	0.000
R84.8 Other abnormal findings	0.002	0.998	0.000
R84.4 Abnormal immunological findings	0.002	0.998	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R84.1 Abnormal level of hormones	0.002	0.998	0.000
R84.0 Abnormal level of enzymes	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.001	0.998	0.000
E34.4 Constitutional tall stature	0.001	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
I23.8 Other current complications following acute myocardial infarction	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.998	0.000
O43.0 Placental transfusion syndromes	0.001	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.002	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.001	0.998	0.000
W21.9 Unspecified place	0.002	0.998	0.000
E11.1 With ketoacidosis	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.001	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
E29 Testicular dysfunction	0.001	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.001	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.001	0.998	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.001	0.998	0.000
M96.4 Postsurgical lordosis	0.001	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.001	0.998	0.000
M96.2 Postradiation kyphosis	0.001	0.998	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.001	0.998	0.000
B37.2 Candidiasis of skin and nail	0.001	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.001	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
E34.8 Other specified endocrine disorders	0.001	0.998	0.000
G54.1 Lumbosacral plexus disorders	0.000	0.998	0.001
J94.8 Other specified pleural conditions	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.001	0.998	0.000
D39.1 Ovary	0.000	0.998	0.002
K07.1 Anomalies of jaw-cranial base relationship	0.001	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.001
G54 Nerve root and plexus disorders	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.001	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.998	0.000
K07.9 Dentofacial anomaly, unspecified	0.001	0.998	0.000
K07.4 Malocclusion, unspecified	0.001	0.998	0.000
R89.8 Other abnormal findings	0.001	0.998	0.000
D12.8 Rectum	0.000	0.999	0.001
E34.0 Carcinoid syndrome	0.001	0.999	0.000
K07.3 Anomalies of tooth position	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.999	0.001
Z43.2 Attention to ileostomy	0.001	0.999	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.001	0.999	0.000
D68.8 Other specified coagulation defects	0.001	0.999	0.000
D68.6 Other Thrombophilia	0.001	0.999	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.999	0.000
O43.8 Other placental disorders	0.001	0.999	0.000
D48.6 Breast	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.001	0.999	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.999	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.001	0.999	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.001	0.999	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.001	0.999	0.000
E29.8 Other testicular dysfunction	0.001	0.999	0.000
E29.0 Testicular hyperfunction	0.001	0.999	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.999	0.001
J94.1 Fibrothorax	0.000	0.999	0.001
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.999	0.001
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.001	0.999	0.000
E83.5 Disorders of calcium metabolism	0.001	0.999	0.000
G54.8 Other nerve root and plexus disorders	0.000	0.999	0.001
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
M25.91 Joint disorder, unspecified (Shoulder region)	0.001	0.999	0.000
R83.8 Other abnormal findings	0.001	0.999	0.000
Z63.4 Disappearance and death of family member	0.001	0.999	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.999	0.001
M79.60 Pain in limb (Multiple sites)	0.000	0.999	0.001
D23.9 Skin, unspecified	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
G54.7 Phantom limb syndrome without pain	0.000	0.999	0.001
G54.3 Thoracic root disorders, not elsewhere classified	0.000	0.999	0.001
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
Z43.0 Attention to tracheostomy	0.001	0.999	0.000
J94 Other pleural conditions	0.000	0.999	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000
E27.9 Disorder of adrenal gland, unspecified	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.999	0.001
G06.2 Extradural and subdural abscess, unspecified	0.000	0.999	0.001
R83.5 Abnormal microbiological findings	0.001	0.999	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.999	0.001
G54.5 Neuralgic amyotrophy	0.000	0.999	0.001
G54.2 Cervical root disorders, not elsewhere classified	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
M54.1 Radiculopathy	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.001	0.999	0.000
R83 Abnormal findings in cerebrospinal fluid	0.001	0.999	0.000
T98 Sequelae of other and unspecified effects of external causes	0.001	0.999	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.001	0.999	0.000
M54.19 Radiculopathy (Site unspecified)	0.001	0.999	0.000
B37.8 Candidiasis of other sites	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.001	0.999	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.999	0.001
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.999	0.001
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
J05.0 Acute obstructive laryngitis [croup]	0.001	0.999	0.000
M14.6 Neuropathic arthropathy	0.001	0.999	0.000
N80.0 Endometriosis of uterus	0.001	0.999	0.000
R86.7 Abnormal histological findings	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.001	0.999	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
T95 Sequelae of burns, corrosions and frostbite	0.001	0.999	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.000	0.999	0.001
H15.1 Episcleritis	0.001	0.999	0.000
O81.0 Low forceps delivery	0.000	0.999	0.001
W17.4 Street and highway	0.000	0.999	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.000	0.999	0.001
J94.0 Chylous effusion	0.000	0.999	0.001
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.999	0.001
O46.9 Antepartum haemorrhage, unspecified	0.001	0.999	0.000
O81.4 Vacuum extractor delivery	0.000	0.999	0.001
Q54.9 Hypospadias, unspecified	0.000	0.999	0.001
R09.2 Respiratory arrest	0.001	0.999	0.000
R86.5 Abnormal microbiological findings	0.001	0.999	0.000
R89.4 Abnormal immunological findings	0.001	0.999	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.001	0.999	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.001	0.999	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
L03.0 Cellulitis of finger and toe	0.000	0.999	0.001
M95.2 Other acquired deformity of head	0.000	0.999	0.001
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
R89.9 Unspecified abnormal finding	0.001	0.999	0.000
R89.7 Abnormal histological findings	0.001	0.999	0.000
R89.6 Abnormal cytological findings	0.001	0.999	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R89.1 Abnormal level of hormones	0.001	0.999	0.000
R89.0 Abnormal level of enzymes	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T98.2 Sequelae of certain early complications of trauma	0.001	0.999	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.001	0.999	0.000
B80 Enterobiasis	0.000	0.999	0.001
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
M24.56 Contracture of joint (Lower leg)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
R83.9 Unspecified abnormal finding	0.001	0.999	0.000
R83.7 Abnormal histological findings	0.001	0.999	0.000
R83.6 Abnormal cytological findings	0.001	0.999	0.000
R83.4 Abnormal immunological findings	0.001	0.999	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R83.1 Abnormal level of hormones	0.001	0.999	0.000
R83.0 Abnormal level of enzymes	0.001	0.999	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.001	0.999	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.001	0.999	0.000
B27.9 Infectious mononucleosis, unspecified	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.999	0.001
I35.2 Aortic (valve) stenosis with insufficiency	0.001	0.999	0.000
R86 Abnormal findings in specimens from male genital organs	0.001	0.999	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
F22.0 Delusional disorder	0.000	0.999	0.001
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.001	0.999	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.001	0.999	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.001	0.999	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.001	0.999	0.000
W21.0 Home	0.001	0.999	0.000
Q05 Spina bifida	0.001	0.999	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.999	0.001
J03.9 Acute tonsillitis, unspecified	0.000	0.999	0.001
R89.5 Abnormal microbiological findings	0.001	0.999	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.001	0.999	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.001	0.999	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.999	0.001
B00.5 Herpesviral ocular disease	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
L30.8 Other specified dermatitis	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
R86.8 Other abnormal findings	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
T94.0 Sequelae of injuries involving multiple body regions	0.001	0.999	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.001	0.999	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999	0.000
H01.0 Blepharitis	0.001	0.999	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.999	0.000
K65.8 Other peritonitis	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
R86.4 Abnormal immunological findings	0.001	0.999	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations