TreeWAS – Variant ID: rs17086954

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.974	0.026
C15.5 Lower third of oesophagus	0.000	0.977	0.023
C15 Malignant neoplasm of oesophagus	0.000	0.981	0.019
C15.3 Upper third of oesophagus	0.000	0.983	0.017
G90.0 Idiopathic peripheral autonomic neuropathy	0.017	0.983	0.000
C15.4 Middle third of oesophagus	0.000	0.984	0.016
C15.9 Oesophagus, unspecified	0.000	0.984	0.016
D24 Benign neoplasm of breast	0.015	0.985	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.015	0.985	0.000
G90 Disorders of autonomic nervous system	0.014	0.986	0.000
Z73.3 Stress, not elsewhere classified	0.014	0.986	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.986	0.014
C15.2 Abdominal part of oesophagus	0.000	0.986	0.014
C15.0 Cervical part of oesophagus	0.000	0.986	0.014
C15.1 Thoracic part of oesophagus	0.000	0.987	0.013
G90.8 Other disorders of autonomic nervous system	0.012	0.988	0.000
G90.3 Multisystem degeneration	0.011	0.989	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.989	0.011
G90.4 Autonomic dysreflexia	0.010	0.989	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.010	0.989	0.000
T43.2 Other and unspecified antidepressants	0.000	0.989	0.011
O24.4 Diabetes mellitus arising in pregnancy	0.010	0.990	0.000
C54.1 Endometrium	0.010	0.990	0.000
D86.0 Sarcoidosis of lung	0.000	0.991	0.009
D86 Sarcoidosis	0.000	0.991	0.009
D86.1 Sarcoidosis of lymph nodes	0.000	0.992	0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.993	0.007
G90.2 Horner's syndrome	0.007	0.993	0.000
H52.2 Astigmatism	0.007	0.993	0.000
S32.10 Fracture of sacrum (closed)	0.007	0.993	0.000
N42.8 Other specified disorders of prostate	0.000	0.993	0.007
T42.4 Benzodiazepines	0.000	0.994	0.006
I27.0 Primary pulmonary hypertension	0.000	0.994	0.006
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.000	0.995	0.005
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.995	0.005
C54 Malignant neoplasm of corpus uteri	0.005	0.995	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.005	0.995	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.995	0.004
F22.0 Delusional disorder	0.005	0.995	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.996	0.004
F10.2 Dependence syndrome	0.000	0.996	0.004
T91.3 Sequelae of injury of spinal cord	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
C54.9 Corpus uteri, unspecified	0.004	0.996	0.000
C54.8 Overlapping lesion of corpus uteri	0.004	0.996	0.000
C54.3 Fundus uteri	0.004	0.996	0.000
C54.2 Myometrium	0.004	0.996	0.000
C54.0 Isthmus uteri	0.004	0.996	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.996	0.004
Z43.6 Attention to other artificial openings of urinary tract	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
T91.1 Sequelae of fracture of spine	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.000
O43.1 Malformation of placenta	0.003	0.997	0.000
O43.8 Other placental disorders	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
Z73 Problems related to life-management difficulty	0.003	0.997	0.000
H60.9 Otitis externa, unspecified	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.000	0.997	0.003
O43 Placental disorders	0.003	0.997	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.003	0.997	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.997	0.003
S32.1 Fracture of sacrum	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.003	0.997	0.000
O43.9 Placental disorder, unspecified	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
F22 Persistent delusional disorders	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
T51.0 Ethanol	0.000	0.997	0.003
Z73.8 Other problems related to life-management difficulty	0.003	0.997	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.997	0.003
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
I49.5 Sick sinus syndrome	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
X68.9 Unspecified place	0.003	0.997	0.000
Z03.3 Observation for suspected nervous system disorder	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
H81.2 Vestibular neuronitis	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
O43.0 Placental transfusion syndromes	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.000	0.997	0.002
Z43.1 Attention to gastrostomy	0.003	0.997	0.000
Z73.5 Social role conflict, not elsewhere classified	0.002	0.997	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.002	0.997	0.000
Z73.2 Lack of relaxation and leisure	0.002	0.997	0.000
Z73.1 Accentuation of personality traits	0.002	0.997	0.000
Z73.0 Burn-out	0.002	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.997	0.000
O43.2 Morbidly adherent placenta	0.002	0.997	0.000
D84 Other immunodeficiencies	0.000	0.997	0.002
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
D68 Other coagulation defects	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
Z43 Attention to artificial openings	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
G83.4 Cauda equina syndrome	0.002	0.998	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.002
D81.8 Other combined immunodeficiencies	0.000	0.998	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.002
D81.4 Nezelof's syndrome	0.000	0.998	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
V44.5 Driver injured in traffic accident	0.002	0.998	0.000
Z43.8 Attention to other artificial openings	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
Z43.3 Attention to colostomy	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
Z43.5 Attention to cyctostomy	0.002	0.998	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.998	0.002
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
N20.0 Calculus of kidney	0.000	0.998	0.002
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M24.0 Loose body in joint	0.002	0.998	0.000
Z43.9 Attention to unspecified artificial opening	0.002	0.998	0.000
Z43.7 Attention to artificial vagina	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
D82.1 Di George's syndrome	0.000	0.998	0.002
D84.1 Defects in the complement system	0.000	0.998	0.002
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.998	0.002
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.998	0.002
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
B99 Other and unspecified infectious diseases	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.001
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.001
T63.4 Venom of other arthropods	0.000	0.998	0.002
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
R87.6 Abnormal cytological findings	0.000	0.998	0.002
S00.0 Superficial injury of scalp	0.000	0.998	0.002
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
Z43.0 Attention to tracheostomy	0.001	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
T63 Toxic effect of contact with venomous animals	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.001	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.001	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
I81 Portal vein thrombosis	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.002	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.001	0.998	0.000
M84.08 Malunion of fracture (Other)	0.001	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.001
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.998	0.000
B18 Chronic viral hepatitis	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.998	0.000
F01 Vascular dementia	0.000	0.998	0.001
F23 Acute and transient psychotic disorders	0.001	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
T58 Toxic effect of carbon monoxide	0.000	0.998	0.001
Z63.0 Problems in relationship with spouse or partner	0.000	0.999	0.001
D66 Hereditary factor VIII deficiency	0.000	0.999	0.001
C53.9 Cervix uteri, unspecified	0.001	0.999	0.000
S00.3 Superficial injury of nose	0.000	0.999	0.001
T13.8 Other specified injuries of lower limb, level unspecified	0.001	0.999	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.001	0.999	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.001	0.999	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.001	0.999	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.001	0.999	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.001	0.999	0.000
T62 Toxic effect of other noxious substances eaten as food	0.000	0.999	0.001
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.001	0.999	0.000
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
F21 Schizotypal disorder	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.999	0.001
R06.2 Wheezing	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
T09.0 Superficial injury of trunk, level unspecified	0.001	0.999	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.000	0.999	0.001
T63.8 Toxic effect of contact with other venomous animals	0.000	0.999	0.001
T63.6 Toxic effect of contact with other marine animals	0.000	0.999	0.001
T63.5 Toxic effect of contact with fish	0.000	0.999	0.001
T63.3 Venom of spider	0.000	0.999	0.001
T63.2 Venom of scorpion	0.000	0.999	0.001
T63.1 Venom of other reptiles	0.000	0.999	0.001
T63.0 Snake venom	0.000	0.999	0.001
G83 Other paralytic syndromes	0.001	0.999	0.000
T65 Toxic effect of other and unspecified substances	0.000	0.999	0.001
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.999	0.000
G30.0 Alzheimer's disease with early onset	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
K65.8 Other peritonitis	0.001	0.999	0.000
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.001	0.999	0.000
T59.9 Gases, fumes and vapours, unspecified	0.000	0.999	0.001
T62.9 Noxious substance eaten as food, unspecified	0.000	0.999	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
H81.3 Other peripheral vertigo	0.001	0.999	0.000
H92.2 Otorrhagia	0.000	0.999	0.001
T09.9 Unspecified injury of trunk, level unspecified	0.001	0.999	0.000
Z99.1 Dependence on respirator	0.000	0.999	0.001
T09 Other injuries of spine and trunk, level unspecified	0.001	0.999	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.999	0.001
T60 Toxic effect of pesticides	0.000	0.999	0.001
T57 Toxic effect of other inorganic substances	0.000	0.999	0.001
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.999	0.001
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.999	0.001
T55 Toxic effect of soaps and detergents	0.000	0.999	0.001
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.999	0.001
B18.9 Chronic viral hepatitis, unspecified	0.001	0.999	0.000
B18.8 Other chronic viral hepatitis	0.001	0.999	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.001	0.999	0.000
O21.2 Late vomiting of pregnancy	0.001	0.999	0.000
T13.1 Open wound of lower limb, level unspecified	0.001	0.999	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.001	0.999	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.001	0.999	0.000
F01.8 Other vascular dementia	0.000	0.999	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.999	0.001
F01.2 Subcortical vascular dementia	0.000	0.999	0.001
F01.1 Multi-infarct dementia	0.000	0.999	0.001
F01.0 Vascular dementia of acute onset	0.000	0.999	0.001
F23.8 Other acute and transient psychotic disorders	0.001	0.999	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.999	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.001	0.999	0.000
G82.3 Flaccid tetraplegia	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.001	0.999	0.000
H92.1 Otorrhoea	0.000	0.999	0.001
M22.4 Chondromalacia patellae	0.001	0.999	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.999	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.001	0.999	0.000
H92 Otalgia and effusion of ear	0.000	0.999	0.001
M84 Disorders of continuity of bone	0.001	0.999	0.000
Z29 Need for other prophylactic measures	0.000	0.999	0.001
T65.9 Toxic effect of unspecified substance	0.000	0.999	0.001
E55 Vitamin D deficiency	0.001	0.999	0.000
T54 Toxic effect of corrosive substances	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M79.11 Myalgia (Shoulder region)	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
T62.8 Other specified noxious substances eaten as food	0.000	0.999	0.001
T62.2 Other ingested (parts of) plant(s)	0.000	0.999	0.001
T62.1 Ingested berries	0.000	0.999	0.001
T62.0 Ingested mushrooms	0.000	0.999	0.001
Z63.5 Disruption of family by separation and divorce	0.000	0.999	0.001
G30 Alzheimer's disease	0.001	0.999	0.000
T52 Toxic effect of organic solvents	0.000	0.999	0.001
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.999	0.000
G82.4 Spastic tetraplegia	0.001	0.999	0.000
M84.8 Other disorders of continuity of bone	0.001	0.999	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.999	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.999	0.001
D04.3 Skin of other and unspecified parts of face	0.000	0.999	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
G83.5 Locked-in syndrome	0.001	0.999	0.000
G83.3 Monoplegia, unspecified	0.001	0.999	0.000
G83.0 Diplegia of upper limbs	0.001	0.999	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.001	0.999	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.999	0.001
T59.7 Carbon dioxide	0.000	0.999	0.001
T59.6 Hydrogen sulphide	0.000	0.999	0.001
T59.5 Fluorine gas and hydrogen fluoride	0.000	0.999	0.001
T59.4 Chlorine gas	0.000	0.999	0.001
T59.3 Lachrymogenic gas	0.000	0.999	0.001
T59.2 Formaldehyde	0.000	0.999	0.001
T59.1 Sulphur dioxide	0.000	0.999	0.001
T59.0 Nitrogen oxides	0.000	0.999	0.001
T65.8 Toxic effect of other specified substances	0.000	0.999	0.001
T65.6 Paints and dyes, not elsewhere classified	0.000	0.999	0.001
T65.5 Nitroglycerin and other nitric acids and esters	0.000	0.999	0.001
T65.4 Carbon disulphide	0.000	0.999	0.001
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.000	0.999	0.001
T65.2 Tobacco and nicotine	0.000	0.999	0.001
T65.1 Strychnine and its salts	0.000	0.999	0.001
T65.0 Cyanides	0.000	0.999	0.001
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.999	0.001
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.001	0.999	0.000
T11 Other injuries of upper limb, level unspecified	0.001	0.999	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
D72.1 Eosinophilia	0.000	0.999	0.001
G03.9 Meningitis, unspecified	0.001	0.999	0.000
O21.9 Vomiting of pregnancy, unspecified	0.001	0.999	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.001	0.999	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.001	0.999	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.001	0.999	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.001	0.999	0.000
T09.3 Injury of spinal cord, level unspecified	0.001	0.999	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.001	0.999	0.000
T09.1 Open wound of trunk, level unspecified	0.001	0.999	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.000	0.999	0.001
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.000	0.999	0.001
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.000	0.999	0.001
T53.5 Chlorofluorocarbons	0.000	0.999	0.001
T53.4 Dichloromethane	0.000	0.999	0.001
T53.3 Tetrachloroethylene	0.000	0.999	0.001
T53.2 Trichloroethylene	0.000	0.999	0.001
T53.1 Chloroform	0.000	0.999	0.001
T53.0 Carbon tetrachloride	0.000	0.999	0.001
T57.9 Inorganic substance, unspecified	0.000	0.999	0.001
T57.8 Other specified inorganic substances	0.000	0.999	0.001
T57.3 Hydrogen cyanide	0.000	0.999	0.001
T57.2 Manganese and its compounds	0.000	0.999	0.001
T57.1 Phosphorus and its compounds	0.000	0.999	0.001
T57.0 Arsenic and its compounds	0.000	0.999	0.001
T60.9 Pesticide, unspecified	0.000	0.999	0.001
T60.8 Other pesticides	0.000	0.999	0.001
T60.4 Rodenticides	0.000	0.999	0.001
T60.3 Herbicides and fungicides	0.000	0.999	0.001
T60.2 Other insecticides	0.000	0.999	0.001
T60.1 Halogenated insecticides	0.000	0.999	0.001
T60.0 Organophosphate and carbamate insecticides	0.000	0.999	0.001
T61.9 Toxic effect of unspecified seafood	0.000	0.999	0.001
T61.8 Toxic effect of other seafoods	0.000	0.999	0.001
T61.2 Other fish and shellfish poisoning	0.000	0.999	0.001
T61.1 Scombroid fish poisoning	0.000	0.999	0.001
T61.0 Ciguatera fish poisoning	0.000	0.999	0.001
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.999	0.001
Z95.8 Presence of other cardiac and vascular implants and grafts	0.001	0.999	0.000
T56 Toxic effect of metals	0.000	0.999	0.001
C62.1 Descended testis	0.000	0.999	0.001
G83.2 Monoplegia of upper limb	0.001	0.999	0.000
V44.6 Passenger injured in traffic accident	0.001	0.999	0.000
V44.9 Unspecified car occupant injured in traffic accident	0.001	0.999	0.000
V44.7 Person on outside of vehicle injured in traffic accident	0.001	0.999	0.000
V44.4 Person injured while boarding or alighting	0.001	0.999	0.000
V44.3 Unspecified car occupant injured in nontraffic accident	0.001	0.999	0.000
V44.2 Person on outside of vehicle injured in nontraffic accident	0.001	0.999	0.000
V44.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V44.0 Driver injured in nontraffic accident	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
D04.7 Skin of lower limb, including hip	0.000	0.999	0.001
E55.0 Rickets, active	0.001	0.999	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.999	0.001
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
X68.8 Other specified place	0.001	0.999	0.000
X68.7 Farm	0.001	0.999	0.000
X68.6 Industrial and construction area	0.001	0.999	0.000
X68.5 Trade and service area	0.001	0.999	0.000
X68.4 Street and highway	0.001	0.999	0.000
X68.3 Sports and athletics area	0.001	0.999	0.000
X68.2 School, other institution and public administrative area	0.001	0.999	0.000
X68.1 Residential institution	0.001	0.999	0.000
X68.0 Home	0.001	0.999	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.999	0.001
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
T54.3 Corrosive alkalis and alklali-like substances	0.000	0.999	0.001
T54.2 Corrosive acids and acid-like substances	0.000	0.999	0.001
T54.1 Other corrosive organic compounds	0.000	0.999	0.001
T54.0 Phenol and phenol homologues	0.000	0.999	0.001
M87 Osteonecrosis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations