TreeWAS – Variant ID: rs1722636

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71.9 Brain, unspecified	0.025	0.975	0.000
C71 Malignant neoplasm of brain	0.024	0.976	0.000
C71.3 Parietal lobe	0.024	0.976	0.000
C71.0 Cerebrum, except lobes and ventricles	0.022	0.978	0.000
C71.2 Temporal lobe	0.022	0.978	0.000
N75.0 Cyst of Bartholin's gland	0.021	0.979	0.000
N90.7 Vulvar cyst	0.019	0.981	0.000
C71.8 Overlapping lesion of brain	0.018	0.982	0.000
C71.7 Brain stem	0.018	0.982	0.000
C71.6 Cerebellum	0.018	0.982	0.000
C71.5 Cerebral ventricle	0.018	0.982	0.000
O63.1 Prolonged second stage (of labour)	0.017	0.983	0.000
N75 Diseases of Bartholin's gland	0.017	0.983	0.000
N75.1 Abscess of Bartholin's gland	0.016	0.984	0.000
C71.4 Occipital lobe	0.015	0.985	0.000
C71.1 Frontal lobe	0.014	0.986	0.000
N75.8 Other diseases of Bartholin's gland	0.014	0.986	0.000
O63 Long labour	0.013	0.987	0.000
O70.0 First degree perineal laceration during delivery	0.013	0.987	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.012	0.988	0.000
O63.0 Prolonged first stage (of labour)	0.012	0.988	0.000
O87 Venous complications in the puerperium	0.012	0.988	0.000
O87.2 Haemorrhoids in the puerperium	0.012	0.988	0.000
O85-O92 Complications predominantly related to the puerperium	0.012	0.988	0.000
O90 Complications of the puerperium, not elsewhere classified	0.012	0.988	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.011	0.989	0.000
O60-O75 Complications of labour and delivery	0.011	0.989	0.000
O69.8 Labour and delivery complicated by other cord complications	0.010	0.990	0.000
O90.9 Complication of the puerperium, unspecified	0.010	0.990	0.000
O90.0 Disruption of Caesarean section wound	0.010	0.990	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.010	0.990	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.010	0.990	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.010	0.990	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.010	0.990	0.000
O26.8 Other specified pregnancy-related conditions	0.010	0.990	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.010	0.990	0.000
O86 Other puerperal infections	0.010	0.990	0.000
O90.1 Disruption of perineal obstetric wound	0.010	0.990	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.010	0.990	0.000
O70 Perineal laceration during delivery	0.009	0.990	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.009	0.991	0.000
O85 Puerperal sepsis	0.009	0.991	0.000
O87.9 Venous complication in the puerperium, unspecified	0.009	0.991	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.009	0.991	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.009	0.991	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.009	0.991	0.000
O89 Complications of anaesthesia during the puerperium	0.009	0.991	0.000
O88 Obstetric embolism	0.009	0.991	0.000
O91 Infections of breast associated with childbirth	0.009	0.991	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.009	0.991	0.000
O90.5 Postpartum thyroiditis	0.008	0.991	0.000
O90.4 Postpartum acute renal failure	0.008	0.991	0.000
O90.3 Cardiomyopathy in the puerperium	0.008	0.991	0.000
C32.0 Glottis	0.000	0.991	0.009
O75 Other complications of labour and delivery, not elsewhere classified	0.008	0.992	0.000
F00 Dementia in Alzheimer's disease	0.008	0.992	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.008	0.992	0.000
O87.8 Other venous complications in the puerperium	0.008	0.992	0.000
O86.0 Infection of obstetric surgical wound	0.008	0.992	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.008	0.992	0.000
O66 Other obstructed labour	0.008	0.992	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.008	0.992	0.000
C32 Malignant neoplasm of larynx	0.000	0.992	0.008
O86.8 Other specified puerperal infections	0.008	0.992	0.000
O90.2 Haematoma of obstetric wound	0.008	0.992	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.008	0.992	0.000
O74 Complications of anaesthesia during labour and delivery	0.008	0.992	0.000
O60 Preterm delivery	0.008	0.992	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.008	0.992	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.008	0.992	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.008	0.992	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.992	0.008
O64.1 Obstructed labour due to breech presentation	0.008	0.992	0.000
O86.4 Pyrexia of unknown origin following delivery	0.008	0.992	0.000
C32.1 Supraglottis	0.000	0.992	0.008
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.007	0.992	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.007	0.993	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.007	0.993	0.000
O64.5 Obstructed labour due to compound presentation	0.007	0.993	0.000
O64.4 Obstructed labour due to shoulder presentation	0.007	0.993	0.000
O64.3 Obstructed labour due to brow presentation	0.007	0.993	0.000
O64.2 Obstructed labour due to face presentation	0.007	0.993	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.007	0.993	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.007	0.993	0.000
O69.3 Labour and delivery complicated by short cord	0.007	0.993	0.000
O75.3 Other infection during labour	0.007	0.993	0.000
O86.3 Other genito-urinary tract infections following delivery	0.007	0.993	0.000
O70.9 Perineal laceration during delivery, unspecified	0.007	0.993	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O67.8 Other intrapartum haemorrhage	0.007	0.993	0.000
O70.3 Fourth degree perineal laceration during delivery	0.007	0.993	0.000
O92.1 Cracked nipple associated with childbirth	0.007	0.993	0.000
O75.8 Other specified complications of labour and delivery	0.007	0.993	0.000
C70 Malignant neoplasm of meninges	0.007	0.993	0.000
O71 Other obstetric trauma	0.007	0.993	0.000
C32.9 Larynx, unspecified	0.000	0.993	0.007
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.007	0.993	0.000
B18.2 Chronic viral hepatitis C	0.007	0.993	0.000
O66.2 Obstructed labour due to unusually large foetus	0.007	0.993	0.000
C34.0 Main bronchus	0.000	0.993	0.007
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.993	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.007	0.993	0.000
O66.4 Failed trial of labour, unspecified	0.007	0.993	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.007	0.993	0.000
O62 Abnormalities of forces of labour	0.007	0.993	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.007	0.993	0.000
O92.7 Other and unspecified disorders of lactation	0.006	0.993	0.000
O92.6 Galactorrhoea	0.006	0.993	0.000
O92.5 Suppressed lactation	0.006	0.993	0.000
O92.4 Hypogalactia	0.006	0.993	0.000
O92.3 Agalactia	0.006	0.993	0.000
O92.0 Retracted nipple associated with childbirth	0.006	0.993	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.007	0.993	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.007	0.993	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.993	0.007
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.006	0.993	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.006	0.993	0.000
O89.6 Failed or difficult intubation during the puerperium	0.006	0.993	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.006	0.993	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.006	0.993	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.006	0.993	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.006	0.993	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.006	0.993	0.000
O86.2 Urinary tract infection following delivery	0.006	0.993	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.006	0.993	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.006	0.993	0.000
O88.8 Other obstetric embolism	0.006	0.993	0.000
O88.3 Obstetric pyaemic and septic embolism	0.006	0.993	0.000
O88.2 Obstetric blood-clot embolism	0.006	0.993	0.000
O88.1 Amniotic fluid embolism	0.006	0.993	0.000
O88.0 Obstetric air embolism	0.006	0.993	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.006	0.993	0.000
O91.0 Infection of nipple associated with childbirth	0.006	0.993	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.993	0.007
O24 Diabetes mellitus in pregnancy	0.006	0.993	0.000
O23 Infections of genito-urinary tract in pregnancy	0.006	0.993	0.000
O91.1 Abscess of breast associated with childbirth	0.006	0.994	0.000
O28 Abnormal findings on antenatal screening of mother	0.006	0.994	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.006	0.994	0.000
G30.9 Alzheimer's disease, unspecified	0.006	0.994	0.000
B18 Chronic viral hepatitis	0.006	0.994	0.000
O75.9 Complication of labour and delivery, unspecified	0.006	0.994	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.006	0.994	0.000
O75.4 Other complications of obstetric surgery and procedures	0.006	0.994	0.000
O75.1 Shock during or following labour and delivery	0.006	0.994	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.006	0.994	0.000
C69 Malignant neoplasm of eye and adnexa	0.006	0.994	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.994	0.006
O69.2 Labour and delivery complicated by other cord entanglement	0.006	0.994	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.006	0.994	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O26.5 Maternal hypotension syndrome	0.006	0.994	0.000
O26.4 Herpes gestationis	0.006	0.994	0.000
O26.1 Low weight gain in pregnancy	0.006	0.994	0.000
O26.0 Excessive weight gain in pregnancy	0.006	0.994	0.000
O66.9 Obstructed labour, unspecified	0.006	0.994	0.000
O66.8 Other specified obstructed labour	0.006	0.994	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.006	0.994	0.000
O66.1 Obstructed labour due to locked twins	0.006	0.994	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.006	0.994	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.006	0.994	0.000
C32.8 Overlapping lesion of larynx	0.000	0.994	0.006
C32.3 Laryngeal cartilage	0.000	0.994	0.006
C32.2 Subglottis	0.000	0.994	0.006
O64.8 Obstructed labour due to other malposition and malpresentation	0.006	0.994	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.994	0.006
C72.0 Spinal cord	0.006	0.994	0.000
B17.1 Acute hepatitis C	0.006	0.994	0.000
B17 Other acute viral hepatitis	0.006	0.994	0.000
O60.3 Preterm delivery without spontaneous labour	0.006	0.994	0.000
O60.2 Preterm spontaneous labour with term delivery	0.006	0.994	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.006	0.994	0.000
O60.0 Preterm labour without delivery	0.006	0.994	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.006	0.994	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.006	0.994	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.006	0.994	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.006	0.994	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.006	0.994	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.006	0.994	0.000
O86.1 Other infection of genital tract following delivery	0.006	0.994	0.000
O29 Complications of anaesthesia during pregnancy	0.006	0.994	0.000
O25 Malnutrition in pregnancy	0.006	0.994	0.000
O61 Failed induction of labour	0.006	0.994	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.994	0.006
I49.0 Ventricular fibrillation and flutter	0.006	0.994	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.006	0.994	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.006	0.994	0.000
O71.8 Other specified obstetric trauma	0.006	0.994	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.006	0.994	0.000
C72.9 Central nervous system, unspecified	0.005	0.994	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.005	0.994	0.000
C72.5 Other and unspecified cranial nerves	0.005	0.994	0.000
C72.4 Acoustic nerve	0.005	0.994	0.000
C72.3 Optic nerve	0.005	0.994	0.000
C72.2 Olfactory nerve	0.005	0.994	0.000
C72.1 Cauda equina	0.005	0.994	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.006	0.994	0.000
O22 Venous complications in pregnancy	0.005	0.994	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.005	0.994	0.000
F01.9 Vascular dementia, unspecified	0.006	0.994	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.994	0.000
O71.5 Other obstetric injury to pelvic organs	0.005	0.994	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.994	0.000
F01 Vascular dementia	0.005	0.994	0.000
B15-B19 Viral hepatitis	0.006	0.994	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.005	0.995	0.000
O71.9 Obstetric trauma, unspecified	0.005	0.995	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.995	0.005
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
O71.3 Obstetric laceration of cervix	0.005	0.995	0.000
O71.2 Postpartum inversion of uterus	0.005	0.995	0.000
O71.1 Rupture of uterus during labour	0.005	0.995	0.000
O71.0 Rupture of uterus before onset of labour	0.005	0.995	0.000
B17.8 Other specified acute viral hepatitis	0.005	0.995	0.000
L53.9 Erythematous condition, unspecified	0.000	0.995	0.005
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.005	0.995	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
O20 Haemorrhage in early pregnancy	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.005	0.995	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.005	0.995	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.005	0.995	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.005	0.995	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.005	0.995	0.000
O65.0 Obstructed labour due to deformed pelvis	0.005	0.995	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.995	0.005
O26.9 Pregnancy-related condition, unspecified	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.005	0.995	0.000
O62.9 Abnormality of forces of labour, unspecified	0.005	0.995	0.000
O62.8 Other abnormalities of forces of labour	0.005	0.995	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
O63.9 Long labour, unspecified	0.005	0.995	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.995	0.005
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.005	0.995	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.005	0.995	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.005	0.995	0.000
O71.7 Obstetric haematoma of pelvis	0.005	0.995	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.005	0.995	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.005	0.995	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.005	0.995	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.005	0.995	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.005	0.995	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.005	0.995	0.000
B16 Acute hepatitis B	0.005	0.995	0.000
B18.9 Chronic viral hepatitis, unspecified	0.005	0.995	0.000
B18.8 Other chronic viral hepatitis	0.005	0.995	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.005	0.995	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.005	0.995	0.000
O62.2 Other uterine inertia	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.005	0.995	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.005	0.995	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
O26.2 Pregnancy care of habitual aborter	0.004	0.995	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.995	0.004
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.005	0.995	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.995	0.005
O62.0 Primary inadequate contractions	0.004	0.995	0.000
B17.9 Acute viral hepatitis, unspecified	0.004	0.995	0.000
B17.2 Acute hepatitis E	0.004	0.995	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.004	0.995	0.000
O62.3 Precipitate labour	0.004	0.995	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.004	0.995	0.000
O61.9 Failed induction of labour, unspecified	0.004	0.995	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.995	0.004
F06.7 Mild cognitive disorder	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.004	0.996	0.000
O23.5 Infections of the genital tract in pregnancy	0.004	0.996	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.004	0.996	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.6 Failed or difficult intubation during pregnancy	0.004	0.996	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.004	0.996	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.004	0.996	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.004	0.996	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.004	0.996	0.000
O61.8 Other failed induction of labour	0.004	0.996	0.000
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.996	0.004
C33 Malignant neoplasm of trachea	0.000	0.996	0.004
O73 Retained placenta and membranes, without haemorrhage	0.004	0.996	0.000
O61.1 Failed instrumental induction of labour	0.004	0.996	0.000
O75.0 Maternal distress during labour and delivery	0.004	0.996	0.000
F09 Unspecified organic or symptomatic mental disorder	0.004	0.996	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.004	0.996	0.000
B15 Acute hepatitis A	0.004	0.996	0.000
C69.9 Eye, unspecified	0.004	0.996	0.000
O22.9 Venous complication in pregnancy, unspecified	0.004	0.996	0.000
O22.8 Other venous complications in pregnancy	0.004	0.996	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.004	0.996	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.004	0.996	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.004	0.996	0.000
O22.1 Genital varices in pregnancy	0.004	0.996	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.996	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.996	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.004	0.996	0.000
F01.8 Other vascular dementia	0.004	0.996	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.004	0.996	0.000
F01.2 Subcortical vascular dementia	0.004	0.996	0.000
F01.1 Multi-infarct dementia	0.004	0.996	0.000
F01.0 Vascular dementia of acute onset	0.004	0.996	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.996	0.004
C31 Malignant neoplasm of accessory sinuses	0.000	0.996	0.004
F05 Delirium, not induced by alcohol and other psychoactive substances	0.004	0.996	0.000
O20.8 Other haemorrhage in early pregnancy	0.004	0.996	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.004	0.996	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.004	0.996	0.000
F06.5 Organic dissociative disorder	0.004	0.996	0.000
F06.4 Organic anxiety disorder	0.004	0.996	0.000
F06.3 Organic mood [affective] disorders	0.004	0.996	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.004	0.996	0.000
F06.1 Organic catatonic disorder	0.004	0.996	0.000
F06.0 Organic hallucinosis	0.004	0.996	0.000
W22.9 Unspecified place	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.000	0.996	0.004
B19 Unspecified viral hepatitis	0.004	0.996	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.996	0.000
F07.0 Organic personality disorder	0.004	0.996	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.004	0.996	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.004	0.996	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.004	0.996	0.000
F02 Dementia in other diseases classified elsewhere	0.004	0.996	0.000
G30 Alzheimer's disease	0.004	0.996	0.000
F80.1 Expressive language disorder	0.004	0.996	0.000
O22.4 Haemorrhoids in pregnancy	0.003	0.996	0.000
O71.4 Obstetric high vaginal laceration alone	0.003	0.996	0.000
C38.4 Pleura	0.000	0.996	0.004
F05.9 Delirium, unspecified	0.004	0.996	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.996	0.004
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.996	0.003
C38.3 Mediastinum, part unspecified	0.000	0.996	0.003
C38.2 Posterior mediastinum	0.000	0.996	0.003
C38.1 Anterior mediastinum	0.000	0.996	0.003
C38.0 Heart	0.000	0.996	0.003
C69.3 Choroid	0.003	0.996	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.003	0.996	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.003	0.996	0.000
F07.1 Postencephalitic syndrome	0.003	0.996	0.000
O00-O08 Pregnancy with abortive outcome	0.004	0.996	0.000
C30.0 Nasal cavity	0.000	0.996	0.003
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.996	0.003
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.996	0.003
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.996	0.003
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.003
O30.0 Twin pregnancy	0.004	0.996	0.000
C30.1 Middle ear	0.000	0.996	0.003
R01.0 Benign and innocent cardiac murmurs	0.003	0.996	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.997	0.003
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
C39.9 Ill-defined sites within the respiratory system	0.000	0.997	0.003
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.997	0.003
C39.0 Upper respiratory tract, part unspecified	0.000	0.997	0.003
F07.2 Postconcussional syndrome	0.003	0.997	0.000
B15.9 Hepatitis A without hepatic coma	0.003	0.997	0.000
L53 Other erythematous conditions	0.000	0.997	0.003
F60 Specific personality disorders	0.003	0.997	0.000
C37 Malignant neoplasm of thymus	0.000	0.997	0.003
O48 Prolonged pregnancy	0.003	0.997	0.000
B15.0 Hepatitis A with hepatic coma	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.000	0.997	0.003
C31.8 Overlapping lesion of accessory sinuses	0.000	0.997	0.003
C31.3 Sphenoidal sinus	0.000	0.997	0.003
C31.2 Frontal sinus	0.000	0.997	0.003
C31.1 Ethmoidal sinus	0.000	0.997	0.003
O21.8 Other vomiting complicating pregnancy	0.003	0.997	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
O21.9 Vomiting of pregnancy, unspecified	0.003	0.997	0.000
O21.2 Late vomiting of pregnancy	0.003	0.997	0.000
F05.1 Delirium superimposed on dementia	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.997	0.003
B19.0 Unspecified viral hepatitis with coma	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.997	0.003
R16.1 Splenomegaly, not elsewhere classified	0.000	0.997	0.003
F02.0 Dementia in Pick's disease	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
F60.2 Dissocial personality disorder	0.003	0.997	0.000
S61.1 Open wound of finger(s) with damage to nail	0.003	0.997	0.000
C31.0 Maxillary sinus	0.000	0.997	0.003
F80 Specific developmental disorders of speech and language	0.003	0.997	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
F02.2 Dementia in Huntington's disease	0.003	0.997	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.003	0.997	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.003	0.997	0.000
O70.2 Third degree perineal laceration during delivery	0.003	0.997	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
J90 Pleural effusion, not elsewhere classified	0.000	0.997	0.003
F60.8 Other specific personality disorders	0.003	0.997	0.000
F60.6 Anxious [avoidant] personality disorder	0.003	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.003	0.997	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.997	0.000
L53.8 Other specified erythematous conditions	0.000	0.997	0.003
B19.9 Unspecified viral hepatitis without coma	0.003	0.997	0.000
S22.3 Fracture of rib	0.000	0.997	0.003
F05.8 Other delirium	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.003	0.997	0.000
F60.0 Paranoid personality disorder	0.003	0.997	0.000
G30.8 Other Alzheimer's disease	0.003	0.997	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.003	0.997	0.000
O30 Multiple gestation	0.003	0.997	0.000
F60.7 Dependent personality disorder	0.003	0.997	0.000
O07 Failed attempted abortion	0.003	0.997	0.000
O06 Unspecified abortion	0.003	0.997	0.000
O05 Other abortion	0.003	0.997	0.000
O01 Hydatidiform mole	0.003	0.997	0.000
B99 Other and unspecified infectious diseases	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.997	0.003
O00 Ectopic pregnancy	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.003	0.997	0.000
F60.1 Schizoid personality disorder	0.003	0.997	0.000
L53.3 Other chronic figurate erythema	0.000	0.997	0.003
L53.2 Erythema marginatum	0.000	0.997	0.003
L53.1 Erythema annulare centrifugum	0.000	0.997	0.003
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.997	0.003
F80.2 Receptive language disorder	0.003	0.997	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.997	0.000
O96.1 Death from indirect obstetric cause	0.002	0.997	0.000
O96.0 Death from direct obstetric cause	0.002	0.997	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.997	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.997	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.997	0.000
F60.5 Anankastic personality disorder	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.997	0.003
O44.1 Placenta praevia with haemorrhage	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.002	0.997	0.001
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.997	0.001
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
L53.0 Toxic erythema	0.000	0.997	0.002
B37.3 Candidiasis of vulva and vagina	0.000	0.997	0.003
K57.2 Diverticular disease of large intestine with perforation and abscess	0.003	0.997	0.000
O04.4 Incomplete, without complication	0.003	0.997	0.000
O03 Spontaneous abortion	0.003	0.997	0.000
O04 Medical abortion	0.003	0.997	0.000
F60-F69 Disorders of adult personality and behaviour	0.003	0.997	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.002	0.997	0.000
O72 Postpartum haemorrhage	0.002	0.997	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.997	0.000
O44 Placenta praevia	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.998	0.002
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.002	0.998	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.002
O30.9 Multiple gestation, unspecified	0.002	0.998	0.000
O30.8 Other multiple gestation	0.002	0.998	0.000
O30.2 Quadruplet pregnancy	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
O00.9 Ectopic pregnancy, unspecified	0.002	0.998	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations