TreeWAS – Variant ID: rs17267338

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O03.4 Incomplete, without complication	0.010	0.990	0.000
S91.3 Open wound of other parts of foot	0.010	0.990	0.000
G40.9 Epilepsy, unspecified	0.000	0.991	0.009
S91 Open wound of ankle and foot	0.008	0.992	0.000
O03 Spontaneous abortion	0.008	0.992	0.000
S91.1 Open wound of toe(s) without damage to nail	0.007	0.992	0.000
Z88.5 Personal history of allergy to narcotic agent	0.007	0.993	0.000
O03.9 Complete or unspecified, without complication	0.007	0.993	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.007	0.993	0.000
S91.0 Open wound of ankle	0.007	0.993	0.000
S91.7 Multiple open wounds of ankle and foot	0.006	0.994	0.000
S91.2 Open wound of toe(s) with damage to nail	0.006	0.994	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.006	0.994	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.006	0.994	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.994	0.006
O03.8 Complete or unspecified, with other and unspecified complications	0.006	0.994	0.000
O03.7 Complete or unspecified, complicated by embolism	0.006	0.994	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.006	0.994	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.006	0.994	0.000
O03.3 Incomplete, with other and unspecified complications	0.006	0.994	0.000
O03.2 Incomplete, complicated by embolism	0.006	0.994	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.006	0.994	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.006	0.994	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.005	0.994	0.000
M54.39 Sciatica (Site unspecified)	0.005	0.995	0.000
G40 Epilepsy	0.000	0.995	0.005
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.005	0.995	0.000
Z88.2 Personal history of allergy to sulphonamides	0.005	0.995	0.000
M54.3 Sciatica	0.005	0.995	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.005	0.995	0.000
M54.36 Sciatica (Lumbar region)	0.005	0.995	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.005	0.995	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.005	0.995	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.995	0.004
I71 Aortic aneurysm and dissection	0.005	0.995	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.004	0.996	0.000
K92.1 Melaena	0.004	0.996	0.000
I72.4 Aneurysm of artery of lower extremity	0.004	0.996	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.996	0.004
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.996	0.004
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.996	0.004
M54.37 Sciatica (Lumbosacral region)	0.004	0.996	0.000
G40.5 Special epileptic syndromes	0.000	0.996	0.004
K92.0 Haematemesis	0.004	0.996	0.000
M54.35 Sciatica (Thoracolumbar region)	0.004	0.996	0.000
M54.34 Sciatica-Thoracic	0.004	0.996	0.000
M54.33 Sciatica-Cervicothoracic	0.004	0.996	0.000
M54.32 Sciatica-Cervical	0.004	0.996	0.000
M54.31 Sciatica-Occipit-atl-axl	0.004	0.996	0.000
M54.30 Sciatica (Multiple sites in spine)	0.004	0.996	0.000
K92 Other diseases of digestive system	0.004	0.996	0.000
I71.0 Dissection of aorta [any part]	0.004	0.996	0.000
K92.9 Disease of digestive system, unspecified	0.004	0.996	0.000
Z71.9 Counselling, unspecified	0.004	0.996	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.003	0.996	0.000
G40.8 Other epilepsy	0.000	0.996	0.003
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.996	0.003
I71.8 Aortic aneurysm of unspecified site, ruptured	0.003	0.996	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.003	0.996	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.003	0.996	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.003	0.996	0.000
K92.8 Other specified diseases of digestive system	0.003	0.996	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.003	0.997	0.000
I72 Other aneurysm	0.003	0.997	0.000
C50.1 Central portion of breast	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
T42.4 Benzodiazepines	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.003	0.997	0.000
Z71.8 Other specified counselling	0.003	0.997	0.000
Z71.2 Person consulting for explanation of investigation findings	0.003	0.997	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.000	0.997	0.003
Z88.3 Personal history of allergy to other anti-infective agents	0.003	0.997	0.000
M75.2 Bicipital tendinitis	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
W22.9 Unspecified place	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M79.0 Rheumatism, unspecified	0.003	0.997	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
S02.6 Fracture of mandible	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.003	0.997	0.000
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
I72.9 Aneurysm of unspecified site	0.003	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.003	0.997	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.003	0.997	0.000
I72.1 Aneurysm of artery of upper extremity	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.003	0.997	0.000
Z71.3 Dietary counselling and surveillance	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.002	0.997	0.000
S97 Crushing injury of ankle and foot	0.002	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.002
S92.7 Multiple fractures of foot	0.002	0.997	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.997	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.997	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.002
I72.8 Aneurysm of other specified arteries	0.002	0.997	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.997	0.003
Z71.6 Tobacco abuse counselling	0.002	0.997	0.000
I78 Diseases of capillaries	0.002	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
K90 Intestinal malabsorption	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
M87 Osteonecrosis	0.002	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
N76.4 Abscess of vulva	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
O04 Medical abortion	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
W22 Striking against or struck by other objects	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O07 Failed attempted abortion	0.002	0.998	0.000
O06 Unspecified abortion	0.002	0.998	0.000
O05 Other abortion	0.002	0.998	0.000
O01 Hydatidiform mole	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.002	0.998	0.000
M48.02 Spinal stenosis (Cervical region)	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
M71.38 Other bursal cyst (Other)	0.002	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.002	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.002	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.002	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.002	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.002	0.998	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.002	0.998	0.000
M90.0 Tuberculosis of bone	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
W22.3 Sports and athletics area	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
Z88.6 Personal history of allergy to analgesic agent	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y95 Nosocomial condition	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
M71.3 Other bursal cyst	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
K90-K93 Other diseases of the digestive system	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
K90.8 Other intestinal malabsorption	0.002	0.998	0.000
K90.3 Pancreatic steatorrhoea	0.002	0.998	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.002	0.998	0.000
K90.1 Tropical sprue	0.002	0.998	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
M71 Other bursopathies	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O04.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O04.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O04.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.998	0.000
O00 Ectopic pregnancy	0.002	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
W22.8 Other specified place	0.002	0.998	0.000
W22.6 Industrial and construction area	0.002	0.998	0.000
W22.4 Street and highway	0.002	0.998	0.000
W22.0 Home	0.002	0.998	0.000
W22.7 Farm	0.002	0.998	0.000
W22.5 Trade and service area	0.002	0.998	0.000
W22.2 School, other institution and public administrative area	0.002	0.998	0.000
W22.1 Residential institution	0.002	0.998	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.44 Lumbago with sciatica-Thoracic	0.002	0.998	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.002	0.998	0.000
M54.42 Lumbago with sciatica-Cervical	0.002	0.998	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.002	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
D48.5 Skin	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
M48.0 Spinal stenosis	0.002	0.998	0.000
M86.8 Other osteomyelitis	0.002	0.998	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
M86.3 Chronic multifocal osteomyelitis	0.002	0.998	0.000
M86.2 Subacute osteomyelitis	0.002	0.998	0.000
M86.1 Other acute osteomyelitis	0.002	0.998	0.000
M86.0 Acute haematogenous osteomyelitis	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
S02.3 Fracture of orbital floor	0.000	0.998	0.002
M60.99 Myositis, unspecified (Site unspecified)	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
O01.9 Hydatidiform mole, unspecified	0.002	0.998	0.000
O01.1 Incomplete and partial hydatidiform mole	0.002	0.998	0.000
O01.0 Classical hydatidiform mole	0.002	0.998	0.000
O05.9 Complete or unspecified, without complication	0.002	0.998	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O05.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O05.4 Incomplete, without complication	0.002	0.998	0.000
O05.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O05.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O06.9 Complete or unspecified, without complication	0.002	0.998	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O06.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O06.4 Incomplete, without complication	0.002	0.998	0.000
O06.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O06.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.002	0.998	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.002	0.998	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.002	0.998	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O07.4 Failed medical abortion, without complication	0.002	0.998	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.002	0.998	0.000
O07.2 Failed medical abortion, complicated by embolism	0.002	0.998	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.002	0.998	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
M71.34 Other bursal cyst (Hand)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
M71.1 Other infective bursitis	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations