TreeWAS – Variant ID: rs17321999

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.001	0.999
I83 Varicose veins of lower extremities	0.000	0.592	0.408
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.695	0.305
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.705	0.295
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.742	0.258
C54.1 Endometrium	0.065	0.935	0.000
C54 Malignant neoplasm of corpus uteri	0.047	0.953	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.965	0.035
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.966	0.034
C51-C58 Malignant neoplasms of female genital organs	0.034	0.966	0.000
C54.8 Overlapping lesion of corpus uteri	0.034	0.966	0.000
C54.3 Fundus uteri	0.034	0.966	0.000
C54.2 Myometrium	0.034	0.966	0.000
C54.0 Isthmus uteri	0.034	0.966	0.000
C54.9 Corpus uteri, unspecified	0.034	0.966	0.000
C56 Malignant neoplasm of ovary	0.033	0.967	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.967	0.033
I87 Other disorders of veins	0.000	0.971	0.029
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.972	0.028
C51 Malignant neoplasm of vulva	0.028	0.972	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.975	0.025
C58 Malignant neoplasm of placenta	0.025	0.975	0.000
I85 Oesophageal varices	0.000	0.975	0.025
C52 Malignant neoplasm of vagina	0.024	0.976	0.000
I81 Portal vein thrombosis	0.000	0.976	0.024
C55 Malignant neoplasm of uterus, part unspecified	0.024	0.976	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.976	0.024
C51.9 Vulva, unspecified	0.023	0.976	0.000
I88 Nonspecific lymphadenitis	0.000	0.977	0.023
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.977	0.023
C53 Malignant neoplasm of cervix uteri	0.022	0.978	0.000
I87.9 Disorder of vein, unspecified	0.000	0.979	0.021
I87.0 Postphlebitic syndrome	0.000	0.979	0.021
C57 Malignant neoplasm of other and unspecified female genital organs	0.021	0.979	0.000
C51.8 Overlapping lesion of vulva	0.020	0.980	0.000
C51.2 Clitoris	0.020	0.980	0.000
C51.1 Labium minus	0.020	0.980	0.000
C51.0 Labium majus	0.020	0.980	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.980	0.020
I87.1 Compression of vein	0.000	0.980	0.020
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.981	0.019
I88.8 Other nonspecific lymphadenitis	0.000	0.983	0.016
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.983	0.016
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.983	0.016
C77.4 Inguinal and lower limb lymph nodes	0.016	0.984	0.000
C57.9 Female genital organ, unspecified	0.016	0.984	0.000
C53.8 Overlapping lesion of cervix uteri	0.016	0.984	0.000
C53.1 Exocervix	0.016	0.984	0.000
C57.8 Overlapping lesion of female genital organs	0.015	0.984	0.000
C57.7 Other specified female genital organs	0.015	0.984	0.000
C57.4 Uterine adnexa, unspecified	0.015	0.984	0.000
C57.3 Parametrium	0.015	0.984	0.000
C57.2 Round ligament	0.015	0.984	0.000
C57.1 Broad ligament	0.015	0.984	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.985	0.015
C53.9 Cervix uteri, unspecified	0.015	0.985	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.985	0.014
I87.8 Other specified disorders of veins	0.000	0.986	0.014
C53.0 Endocervix	0.013	0.987	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.987	0.013
K90.0 Coeliac disease	0.013	0.987	0.000
I86 Varicose veins of other sites	0.000	0.987	0.013
C78.2 Secondary malignant neoplasm of pleura	0.012	0.988	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.012	0.988	0.000
C57.0 Fallopian tube	0.011	0.989	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.989	0.011
C80.9 Malignant neoplasm, unspecified	0.011	0.989	0.000
C77.3 Axillary and upper limb lymph nodes	0.011	0.989	0.000
I82 Other venous embolism and thrombosis	0.000	0.989	0.011
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.989	0.011
S92.3 Fracture of metatarsal bone	0.000	0.990	0.010
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.990	0.010
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.010	0.990	0.000
I86.3 Vulval varices	0.000	0.991	0.009
I86.0 Sublingual varices	0.000	0.991	0.009
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.009	0.991	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.009	0.991	0.000
C80 Malignant neoplasm without specification of site	0.009	0.991	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.009	0.991	0.000
I86.2 Pelvic varices	0.000	0.991	0.009
C78.4 Secondary malignant neoplasm of small intestine	0.008	0.992	0.000
S92 Fracture of foot, except ankle	0.000	0.992	0.008
I86.4 Gastric varices	0.000	0.992	0.008
I82.1 Thrombophlebitis migrans	0.000	0.992	0.008
I82.0 Budd-Chiari syndrome	0.000	0.992	0.008
S92.31 Fracture of metatarsal bone (open)	0.000	0.992	0.008
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.008	0.992	0.000
S92.0 Fracture of calcaneus	0.000	0.992	0.008
I86.8 Varicose veins of other specified sites	0.000	0.992	0.007
D50.8 Other iron deficiency anaemias	0.007	0.993	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.993	0.007
K86.2 Cyst of pancreas	0.000	0.993	0.007
R14 Flatulence and related conditions	0.007	0.993	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.993	0.007
C76 Malignant neoplasm of other and ill-defined sites	0.007	0.993	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.993	0.007
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.993	0.007
S92.4 Fracture of great toe	0.000	0.993	0.007
C76.2 Abdomen	0.006	0.993	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.006	0.993	0.000
S92.7 Multiple fractures of foot	0.000	0.993	0.006
I89.1 Lymphangitis	0.000	0.994	0.006
S92.5 Fracture of other toe	0.000	0.994	0.006
S92.2 Fracture of other tarsal bone(s)	0.000	0.994	0.006
S92.9 Fracture of foot, unspecified	0.000	0.994	0.006
C77.5 Intrapelvic lymph nodes	0.006	0.994	0.000
C76.3 Pelvis	0.006	0.994	0.000
C77.8 Lymph nodes of multiple regions	0.006	0.994	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.994	0.006
S92.1 Fracture of talus	0.000	0.994	0.006
K86.1 Other chronic pancreatitis	0.000	0.994	0.006
S92.40 Fracture of great toe (closed)	0.000	0.994	0.006
S92.01 Fracture of calcaneus (open)	0.000	0.994	0.006
M13.90 Arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
S92.41 Fracture of great toe (open)	0.000	0.994	0.005
I86.1 Scrotal varices	0.000	0.994	0.005
I84.5 External haemorrhoids without complication	0.006	0.994	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.005	0.994	0.000
C76.7 Other ill-defined sites	0.005	0.994	0.000
C76.5 Lower limb	0.005	0.994	0.000
C76.4 Upper limb	0.005	0.994	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.995	0.005
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
C77.2 Intra-abdominal lymph nodes	0.005	0.995	0.000
C78.0 Secondary malignant neoplasm of lung	0.005	0.995	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.995	0.005
C76.1 Thorax	0.005	0.995	0.000
M13.9 Arthritis, unspecified	0.005	0.995	0.000
K90 Intestinal malabsorption	0.005	0.995	0.000
K86 Other diseases of pancreas	0.000	0.995	0.005
C77.9 Lymph node, unspecified	0.005	0.995	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.995	0.005
S92.50 Fracture of other toe (closed)	0.000	0.995	0.005
S92.71 Multiple fractures of foot (open)	0.000	0.995	0.005
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.995	0.005
K86.8 Other specified diseases of pancreas	0.000	0.995	0.005
S92.51 Fracture of other toe (open)	0.000	0.995	0.005
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
S92.91 Fracture of foot, unspecified (open)	0.000	0.995	0.005
S92.90 Fracture of foot, unspecified (closed)	0.000	0.995	0.005
I82.2 Embolism and thrombosis of vena cava	0.001	0.995	0.004
R50.9 Fever, unspecified	0.005	0.995	0.000
S92.11 Fracture of talus (open)	0.000	0.995	0.004
M13.93 Arthritis, unspecified (Forearm)	0.004	0.996	0.000
K90.8 Other intestinal malabsorption	0.004	0.996	0.000
R94.5 Abnormal results of liver function studies	0.000	0.996	0.004
M13.98 Arthritis, unspecified (Other)	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.000	0.996	0.004
D50 Iron deficiency anaemia	0.004	0.996	0.000
C76.0 Head, face and neck	0.004	0.996	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.004	0.996	0.000
K90.3 Pancreatic steatorrhoea	0.004	0.996	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.004	0.996	0.000
K90.1 Tropical sprue	0.004	0.996	0.000
M95.0 Acquired deformity of nose	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
M13.99 Arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.996	0.004
M13.92 Arthritis, unspecified (Upper arm)	0.004	0.996	0.000
T42.1 Iminostilbenes	0.000	0.996	0.004
C44.5 Skin of trunk	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
N89.8 Other specified noninflammatory disorders of vagina	0.004	0.996	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.004	0.996	0.000
N60.4 Mammary duct ectasia	0.004	0.996	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.003	0.996	0.000
K86.3 Pseudocyst of pancreas	0.000	0.996	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.004	0.996	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
M13 Other arthritis	0.003	0.997	0.000
K90.9 Intestinal malabsorption, unspecified	0.003	0.997	0.000
D50.1 Sideropenic dysphagia	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.003	0.997	0.000
R68.8 Other specified general symptoms and signs	0.003	0.997	0.000
K00.6 Disturbances in tooth eruption	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M13.94 Arthritis, unspecified (Hand)	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
K81.1 Chronic cholecystitis	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
Y54.5 Other diuretics	0.000	0.997	0.003
D56.3 Thalassaemia trait	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
M13.1 Monoarthritis, not elsewhere classified	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.003	0.997	0.000
M13.8 Other specified arthritis	0.003	0.997	0.000
M13.0 Polyarthritis, unspecified	0.003	0.997	0.000
R54 Senility	0.003	0.997	0.000
M95.4 Acquired deformity of chest and rib	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.002	0.997	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.997	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
N97.1 Female infertility of tubal origin	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
D56 Thalassaemia	0.003	0.997	0.000
D53 Other nutritional anaemias	0.002	0.997	0.000
R68 Other general symptoms and signs	0.003	0.997	0.000
D73.0 Hyposplenism	0.003	0.997	0.000
C22.9 Liver, unspecified	0.000	0.997	0.003
D80-D89 Certain disorders involving the immune mechanism	0.002	0.997	0.000
O80.0 Spontaneous vertex delivery	0.000	0.998	0.002
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
J94.2 Haemothorax	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
R68.2 Dry mouth, unspecified	0.002	0.998	0.000
D16.1 Short bones of upper limb	0.002	0.998	0.000
N89.5 Stricture and atresia of vagina	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.002	0.998	0.000
M95.1 Cauliflower ear	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M13.18 Monoarthritis, not elsewhere classified (Other)	0.002	0.998	0.000
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.002	0.998	0.000
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.002	0.998	0.000
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
R68.3 Clubbing of fingers	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
N89 Other noninflammatory disorders of vagina	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M13.88 Other specified arthritis (Other)	0.002	0.998	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.002	0.998	0.000
M13.86 Other specified arthritis (Lower leg)	0.002	0.998	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M13.84 Other specified arthritis (Hand)	0.002	0.998	0.000
M13.83 Other specified arthritis (Forearm)	0.002	0.998	0.000
M13.82 Other specified arthritis (Upper arm)	0.002	0.998	0.000
M13.81 Other specified arthritis (Shoulder region)	0.002	0.998	0.000
M13.80 Other specified arthritis (Multiple sites)	0.002	0.998	0.000
D12.0 Caecum	0.000	0.998	0.002
M13.08 Polyarthritis, unspecified (Other)	0.002	0.998	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.002	0.998	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.002	0.998	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.002	0.998	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.002	0.998	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
M13.89 Other specified arthritis (Site unspecified)	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
D73 Diseases of spleen	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.000	0.998	0.002
K35.9 Acute appendicitis, unspecified	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
X10.0 Home	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.002	0.998	0.000
N89.7 Haematocolpos	0.002	0.998	0.000
N89.4 Leukoplakia of vagina	0.002	0.998	0.000
N89.3 Dysplasia of vagina, unspecified	0.002	0.998	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.002	0.998	0.000
N89.1 Moderate vaginal dysplasia	0.002	0.998	0.000
N89.0 Mild vaginal dysplasia	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M07.6 Other enteropathic arthropathies	0.002	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.002	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.998	0.000
M07.2 Psoriatic spondylitis	0.002	0.998	0.000
M07.1 Arthritis mutilans	0.002	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
J94.1 Fibrothorax	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
X58.9 Unspecified place	0.002	0.998	0.000
M05-M14 Inflammatory polyarthropathies	0.002	0.998	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.002
J94 Other pleural conditions	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
B59 Pneumocystosis	0.002	0.998	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.002	0.998	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.998	0.000
D51.2 Transcobalamin II deficiency	0.001	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.998	0.000
D73.1 Hypersplenism	0.001	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
N60 Benign mammary dysplasia	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.001
A41.8 Other specified septicaemia	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
N60.0 Solitary cyst of breast	0.002	0.998	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.001	0.998	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.001	0.998	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.001	0.998	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.001	0.998	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.001	0.998	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.001	0.998	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.001	0.998	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.001	0.998	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.001	0.998	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.001	0.998	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.001	0.998	0.000
M07.18 Arthritis mutilans (Other)	0.001	0.998	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.001	0.998	0.000
M07.16 Arthritis mutilans (Lower leg)	0.001	0.998	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.001	0.998	0.000
M07.14 Arthritis mutilans (Hand)	0.001	0.998	0.000
M07.13 Arthritis mutilans (Forearm)	0.001	0.998	0.000
M07.12 Arthritis mutilans (Upper arm)	0.001	0.998	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.001	0.998	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.001	0.998	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.001	0.998	0.000
M07.28 Psoriatic spondylitis (Other)	0.001	0.998	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.001	0.998	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.001	0.998	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.001	0.998	0.000
M07.24 Psoriatic spondylitis (Hand)	0.001	0.998	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.001	0.998	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.001	0.998	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.001	0.998	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.001	0.998	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.001	0.998	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.001	0.998	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.001	0.998	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.001	0.998	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.001	0.998	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.001	0.998	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.001	0.998	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.001	0.998	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.001	0.998	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.001	0.998	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.001	0.998	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.001	0.998	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.001	0.998	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.001	0.998	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.001	0.998	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.001	0.998	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.001	0.998	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.001	0.998	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.001	0.998	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.001	0.998	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.001	0.998	0.000
M07.68 Other enteropathic arthropathies (Other)	0.001	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
N89.6 Tight hymenal ring	0.001	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.001
M12 Other specific arthropathies	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations