TreeWAS – Variant ID: rs17404956

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.913	0.087
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.934	0.066
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.939	0.061
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.939	0.061
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.948	0.052
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.950	0.050
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.956	0.044
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.959	0.041
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.967	0.033
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.968	0.032
Z88.1 Personal history of allergy to other antibiotic agents	0.022	0.978	0.000
B95-B98 Bacterial, viral and other infectious agents	0.000	0.987	0.013
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.989	0.010
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.990	0.010
H33.2 Serous retinal detachment	0.000	0.991	0.009
K92.0 Haematemesis	0.008	0.992	0.000
H18 Other disorders of cornea	0.000	0.992	0.008
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.992	0.008
F17.2 Dependence syndrome	0.008	0.992	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.992	0.008
H18.4 Corneal degeneration	0.000	0.992	0.008
Y44.2 Anticoagulants	0.008	0.992	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.993	0.007
H18.8 Other specified disorders of cornea	0.000	0.993	0.007
K60.2 Anal fissure, unspecified	0.007	0.993	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.993	0.007
H18.2 Other corneal oedema	0.000	0.994	0.006
H02.1 Ectropion of eyelid	0.006	0.994	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.994	0.006
H18.6 Keratoconus	0.000	0.994	0.006
H18.7 Other corneal deformities	0.000	0.994	0.006
H18.3 Changes in corneal membranes	0.000	0.994	0.006
H18.1 Bullous keratopathy	0.000	0.994	0.006
H18.0 Corneal pigmentations and deposits	0.000	0.994	0.006
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.994	0.006
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
L03.3 Cellulitis of trunk	0.000	0.995	0.005
R49.0 Dysphonia	0.005	0.995	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.995	0.005
K60 Fissure and fistula of anal and rectal regions	0.005	0.995	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.995	0.005
Z09.2 Follow-up examination after chemotherapy for other conditions	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
H21 Other disorders of iris and ciliary body	0.000	0.996	0.004
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.996	0.004
K60.5 Anorectal fistula	0.004	0.996	0.000
K60.0 Acute anal fissure	0.004	0.996	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.996	0.004
B37.8 Candidiasis of other sites	0.004	0.996	0.000
N92.3 Ovulation bleeding	0.004	0.996	0.000
H33 Retinal detachments and breaks	0.000	0.996	0.004
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
H17 Corneal scars and opacities	0.000	0.996	0.004
Z88.3 Personal history of allergy to other anti-infective agents	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.000	0.996	0.004
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.996	0.003
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.996	0.003
H15 Disorders of sclera	0.000	0.996	0.003
D63.0 Anaemia in neoplastic disease	0.004	0.996	0.000
K60.4 Rectal fistula	0.003	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
H20 Iridocyclitis	0.000	0.996	0.003
M50.1 Cervical disk disorder with radiculopathy	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.997	0.003
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.997	0.003
H21.4 Pupillary membranes	0.000	0.997	0.003
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.997	0.003
H21.2 Degeneration of iris and ciliary body	0.000	0.997	0.003
K60.3 Anal fistula	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.997	0.003
H33.1 Retinoschisis and retinal cysts	0.000	0.997	0.003
K60.1 Chronic anal fissure	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
H33.4 Traction detachment of retina	0.000	0.997	0.003
R49 Voice disturbances	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
H21.0 Hyphaema	0.000	0.997	0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.000	0.997	0.003
H17.1 Other central corneal opacity	0.000	0.997	0.003
H17.0 Adherent leukoma	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
R49.8 Other and unspecified voice disturbances	0.003	0.997	0.000
H16 Keratitis	0.000	0.997	0.003
H33.3 Retinal breaks without detachment	0.000	0.997	0.003
H15.9 Disorder of sclera, unspecified	0.000	0.997	0.003
H15.8 Other disorders of sclera	0.000	0.997	0.003
H15.1 Episcleritis	0.000	0.997	0.003
H15.0 Scleritis	0.000	0.997	0.003
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.997	0.003
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.997	0.003
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.000	0.997	0.003
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.997	0.003
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.997	0.002
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.997	0.003
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.997	0.003
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.003
H20.1 Chronic iridocyclitis	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.997	0.002
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.997	0.003
R49.2 Hypernasality and hyponasality	0.002	0.997	0.000
R49.1 Aphonia	0.002	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.002
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.002
U80.1 Methicillin resistant agent	0.002	0.997	0.000
Y40.8 Other systemic antibiotics	0.002	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
R32 Unspecified urinary incontinence	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
D33.3 Cranial nerves	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
L03 Cellulitis	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.002	0.998	0.000
H16.8 Other keratitis	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.000	0.998	0.002
H16.3 Interstitial and deep keratitis	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.000	0.998	0.002
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
L03.9 Cellulitis, unspecified	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.998	0.002
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
H33.5 Other retinal detachments	0.001	0.998	0.001
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.002	0.998	0.000
J06.0 Acute laryngopharyngitis	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
L03.2 Cellulitis of face	0.000	0.998	0.002
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
C32 Malignant neoplasm of larynx	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
B37 Candidiasis	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.001	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
C32.1 Supraglottis	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.001	0.998	0.000
Y52.1 Calcium-channel blockers	0.001	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
D33.2 Brain, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.001	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
F17 Mental and behavioural disorders due to use of tobacco	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.998	0.000
Q23.2 Congenital mitral stenosis	0.001	0.998	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
C44.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.001	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.001	0.998	0.000
D33.4 Spinal cord	0.001	0.998	0.000
E28.3 Primary ovarian failure	0.000	0.998	0.001
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.001
E32 Diseases of thymus	0.000	0.998	0.001
E31 Polyglandular dysfunction	0.000	0.998	0.001
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.001
E25 Adrenogenital disorders	0.000	0.998	0.001
E22 Hyperfunction of pituitary gland	0.000	0.998	0.001
Q51 Congenital malformations of uterus and cervix	0.001	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.001
E28.8 Other ovarian dysfunction	0.000	0.998	0.001
E28.1 Androgen excess	0.000	0.998	0.001
E28.0 Oestrogen excess	0.000	0.998	0.001
Q51.2 Other doubling of uterus	0.001	0.998	0.000
S93.0 Dislocation of ankle joint	0.001	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
E26 Hyperaldosteronism	0.000	0.998	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.998	0.000
Y40.0 Penicillins	0.001	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.001
M84.06 Malunion of fracture (Lower leg)	0.001	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.001
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
J03 Acute tonsillitis	0.000	0.998	0.001
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
D61.1 Drug-induced aplastic anaemia	0.001	0.999	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.999	0.001
S80.9 Superficial injury of lower leg, unspecified	0.000	0.999	0.001
C32.8 Overlapping lesion of larynx	0.001	0.999	0.000
C32.3 Laryngeal cartilage	0.001	0.999	0.000
C32.2 Subglottis	0.001	0.999	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.999	0.001
Q53.9 Undescended testicle, unspecified	0.001	0.999	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.999	0.000
Q53.0 Ectopic testis	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
E24 Cushing's syndrome	0.000	0.999	0.001
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.999	0.000
Q55 Other congenital malformations of male genital organs	0.001	0.999	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
B37.7 Candidal septicaemia	0.001	0.999	0.000
B37.6 Candidal endocarditis	0.001	0.999	0.000
B37.5 Candidal meningitis	0.001	0.999	0.000
B37.2 Candidiasis of skin and nail	0.001	0.999	0.000
B37.1 Pulmonary candidiasis	0.001	0.999	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.000	0.999	0.001
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.999	0.000
Q50.5 Embryonic cyst of broad ligament	0.001	0.999	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.999	0.000
Q50.2 Congenital torsion of ovary	0.001	0.999	0.000
Q50.1 Developmental ovarian cyst	0.001	0.999	0.000
Q50.0 Congenital absence of ovary	0.001	0.999	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.999	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.999	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.999	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.999	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.999	0.000
Q52.3 Imperforate hymen	0.001	0.999	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.999	0.000
Q52.1 Doubling of vagina	0.001	0.999	0.000
Q52.0 Congenital absence of vagina	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.999	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.999	0.001
E23.0 Hypopituitarism	0.000	0.999	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
E29 Testicular dysfunction	0.000	0.999	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.999	0.001
E21.4 Other specified disorders of parathyroid gland	0.000	0.999	0.001
E21.2 Other hyperparathyroidism	0.000	0.999	0.001
F17.9 Unspecified mental and behavioural disorder	0.001	0.999	0.000
F17.8 Other mental and behavioural disorders	0.001	0.999	0.000
F17.7 Residual and late-onset psychotic disorder	0.001	0.999	0.000
F17.6 Amnesic syndrome	0.001	0.999	0.000
F17.5 Psychotic disorder	0.001	0.999	0.000
F17.4 Withdrawal state with delirium	0.001	0.999	0.000
F17.3 Withdrawal state	0.001	0.999	0.000
F17.0 Acute intoxication	0.001	0.999	0.000
E34 Other endocrine disorders	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
S02.50 Fracture of tooth (closed)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
H40.0 Glaucoma suspect	0.000	0.999	0.001
K76.9 Liver disease, unspecified	0.000	0.999	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
D33.9 Central nervous system, unspecified	0.001	0.999	0.000
D33.7 Other specified parts of central nervous system	0.001	0.999	0.000
D33.1 Brain, infratentorial	0.001	0.999	0.000
D33.0 Brain, supratentorial	0.001	0.999	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.999	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.999	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.999	0.001
E25.8 Other adrenogenital disorders	0.000	0.999	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.999	0.001
E30.9 Disorder of puberty, unspecified	0.000	0.999	0.001
E30.8 Other disorders of puberty	0.000	0.999	0.001
E30.1 Precocious puberty	0.000	0.999	0.001
E30.0 Delayed puberty	0.000	0.999	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.999	0.001
E31.8 Other polyglandular dysfunction	0.000	0.999	0.001
E31.1 Polyglandular hyperfunction	0.000	0.999	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations