TreeWAS – Variant ID: rs17550532

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.177	0.823	0.000
I69 Sequelae of cerebrovascular disease	0.163	0.837	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.147	0.853	0.000
I69.3 Sequelae of cerebral infarction	0.141	0.859	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.139	0.861	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.108	0.891	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.103	0.896	0.000
I60-I69 Cerebrovascular diseases	0.090	0.910	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.079	0.921	0.000
I63 Cerebral infarction	0.079	0.921	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.076	0.924	0.000
I61 Intracerebral haemorrhage	0.075	0.925	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.075	0.925	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.072	0.928	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.070	0.930	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.068	0.932	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.066	0.934	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.065	0.935	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.064	0.935	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.063	0.937	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.063	0.937	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.061	0.939	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.059	0.941	0.000
I61.8 Other intracerebral haemorrhage	0.058	0.942	0.000
I62 Other nontraumatic intracranial haemorrhage	0.058	0.942	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.058	0.942	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.057	0.943	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.057	0.943	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.057	0.943	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.057	0.943	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.057	0.943	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.056	0.943	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.056	0.943	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.056	0.944	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.054	0.946	0.000
I65.2 Occlusion and stenosis of carotid artery	0.053	0.947	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.052	0.947	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.052	0.948	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.052	0.948	0.000
I65.1 Occlusion and stenosis of basilar artery	0.052	0.948	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.051	0.949	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.049	0.951	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.047	0.953	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.047	0.953	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.047	0.953	0.000
I68.0 Cerebral amyloid angiopathy	0.046	0.953	0.000
I62.1 Nontraumatic extradural haemorrhage	0.042	0.958	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.038	0.962	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.036	0.964	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.035	0.964	0.000
I63.8 Other cerebral infarction	0.030	0.970	0.000
I60 Subarachnoid haemorrhage	0.028	0.972	0.000
I63.9 Cerebral infarction, unspecified	0.025	0.975	0.000
I60.8 Other subarachnoid haemorrhage	0.022	0.977	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.020	0.980	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.020	0.980	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.020	0.980	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.019	0.981	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.018	0.982	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.983	0.017
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.017	0.983	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.016	0.984	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.016	0.984	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.016	0.984	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.015	0.985	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.986	0.014
D75 Other diseases of blood and blood-forming organs	0.000	0.986	0.014
D75.2 Essential thrombocytosis	0.000	0.987	0.013
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.987	0.013
D75.1 Secondary polycythaemia	0.000	0.987	0.013
D75.0 Familial erythrocytosis	0.000	0.990	0.010
I67 Other cerebrovascular diseases	0.009	0.991	0.000
C91 Lymphoid leukaemia	0.000	0.992	0.008
D68.6 Other Thrombophilia	0.008	0.992	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.008	0.992	0.000
D69 Purpura and other haemorrhagic conditions	0.008	0.992	0.000
D68 Other coagulation defects	0.008	0.992	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.008	0.992	0.000
K37 Unspecified appendicitis	0.008	0.992	0.000
D68.9 Coagulation defect, unspecified	0.008	0.992	0.000
K12.2 Cellulitis and abscess of mouth	0.008	0.992	0.000
D69.6 Thrombocytopenia, unspecified	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.007	0.992	0.000
I67.2 Cerebral atherosclerosis	0.007	0.993	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.007	0.993	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
C91.4 Hairy-cell leukaemia	0.000	0.993	0.007
O02.1 Missed abortion	0.007	0.993	0.000
D68.0 Von Willebrand's disease	0.007	0.993	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.993	0.007
I67.7 Cerebral arteritis, not elsewhere classified	0.007	0.993	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.007	0.993	0.000
I67.5 Moyamoya disease	0.007	0.993	0.000
I67.4 Hypertensive encephalopathy	0.007	0.993	0.000
I67.3 Progressive vascular leukoencephalopathy	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.006	0.993	0.000
C91.0 Acute lymphoblastic leukaemia	0.000	0.993	0.006
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.994	0.006
C91.7 Other lymphoid leukaemia	0.000	0.994	0.006
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.994	0.006
C91.3 Prolymphocytic leukaemia	0.000	0.994	0.006
C91.2 Subacute lymphocytic leukaemia	0.000	0.994	0.006
M05.9 Seropositive rheumatoid arthritis, unspecified	0.006	0.994	0.000
D69.9 Haemorrhagic condition, unspecified	0.006	0.994	0.000
K12 Stomatitis and related lesions	0.006	0.994	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.006	0.994	0.000
D69.8 Other specified haemorrhagic conditions	0.006	0.994	0.000
D69.5 Secondary thrombocytopenia	0.006	0.994	0.000
D69.1 Qualitative platelet defects	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
K85.9 Acute pancreatitis, unspecified	0.006	0.994	0.000
D68.4 Acquired coagulation factor deficiency	0.006	0.994	0.000
D68.1 Hereditary factor XI deficiency	0.006	0.994	0.000
C91.5 Adult T-cell leukaemia	0.000	0.994	0.006
D69.4 Other primary thrombocytopenia	0.006	0.994	0.000
K12.3 Oral mucositis (ulcerative)	0.006	0.994	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.005	0.994	0.000
K12.1 Other forms of stomatitis	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
D69.0 Allergic purpura	0.005	0.995	0.000
K12.0 Recurrent oral aphthae	0.005	0.995	0.000
D89.1 Cryoglobulinaemia	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.005	0.995	0.000
H11.0 Pterygium	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.995	0.005
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.005	0.995	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.005	0.995	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.005	0.995	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.005	0.995	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.995	0.000
H11 Other disorders of conjunctiva	0.005	0.995	0.000
H11.9 Disorder of conjunctiva, unspecified	0.005	0.995	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.005	0.995	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.995	0.005
S22.40 Multiple fractures of ribs (closed)	0.005	0.995	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.995	0.000
D89.3 Immune reconstitution syndrome	0.004	0.995	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.995	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
Z57.3 Occupational exposure to other air contaminants	0.004	0.996	0.000
M05.2 Rheumatoid vasculitis	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
K35-K38 Diseases of appendix	0.004	0.996	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.996	0.004
H11.3 Conjunctival haemorrhage	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
H11.8 Other specified disorders of conjunctiva	0.004	0.996	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.004	0.996	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.004	0.996	0.000
M24.57 Contracture of joint (Ankle and foot)	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
H53.4 Visual field defects	0.004	0.996	0.000
K02.9 Dental caries, unspecified	0.000	0.996	0.004
M05.20 Rheumatoid vasculitis (Multiple sites)	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.004	0.996	0.000
H11.1 Conjunctival degenerations and deposits	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.004	0.996	0.000
H11.2 Conjunctival scars	0.003	0.996	0.000
K35 Acute appendicitis	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.996	0.004
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.996	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.003	0.997	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.003	0.997	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.003	0.997	0.000
K36 Other appendicitis	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.003
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
K35.3 Acute appendicitis with localized peritonitis	0.003	0.997	0.000
M05.28 Rheumatoid vasculitis (Other)	0.003	0.997	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.003	0.997	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.003	0.997	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.003	0.997	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.003	0.997	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.003	0.997	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.003	0.997	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
H10 Conjunctivitis	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
K38 Other diseases of appendix	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
D72 Other disorders of white blood cells	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.997	0.003
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.003	0.997	0.000
M24.2 Disorder of ligament	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.003	0.997	0.000
M24.0 Loose body in joint	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
K38.1 Appendicular concretions	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.997	0.003
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
M05.09 Felty's syndrome (Site unspecified)	0.003	0.997	0.000
M05.08 Felty's syndrome (Other)	0.003	0.997	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.003	0.997	0.000
M05.06 Felty's syndrome (Lower leg)	0.003	0.997	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.003	0.997	0.000
M05.04 Felty's syndrome (Hand)	0.003	0.997	0.000
M05.03 Felty's syndrome (Forearm)	0.003	0.997	0.000
M05.02 Felty's syndrome (Upper arm)	0.003	0.997	0.000
M05.01 Felty's syndrome (Shoulder region)	0.003	0.997	0.000
M05.00 Felty's syndrome (Multiple sites)	0.003	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.003	0.997	0.000
M05.18 Rheumatoid lung disease (Other)	0.003	0.997	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.003	0.997	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.003	0.997	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.003	0.997	0.000
M05.14 Rheumatoid lung disease (Hand)	0.003	0.997	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.003	0.997	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.003	0.997	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.003	0.997	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.003	0.997	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.003	0.997	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.003	0.997	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.003	0.997	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.003	0.997	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.003	0.997	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.003	0.997	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.003	0.997	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.003	0.997	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.003	0.997	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.003	0.997	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.003	0.997	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.003	0.997	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.003	0.997	0.000
D13.2 Duodenum	0.003	0.997	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.003
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.003
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
R63.0 Anorexia	0.003	0.997	0.000
S22.5 Flail chest	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
D74 Methaemoglobinaemia	0.000	0.997	0.002
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.997	0.002
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.997	0.002
D84 Other immunodeficiencies	0.002	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
H61.2 Impacted cerumen	0.000	0.997	0.003
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.002	0.997	0.000
H10.8 Other conjunctivitis	0.002	0.997	0.000
H10.5 Blepharoconjunctivitis	0.002	0.997	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.997	0.000
H10.2 Other acute conjunctivitis	0.002	0.997	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.997	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.997	0.000
C71.7 Brain stem	0.002	0.997	0.000
C71.6 Cerebellum	0.002	0.997	0.000
C71.5 Cerebral ventricle	0.002	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.997	0.000
K38.3 Fistula of appendix	0.002	0.997	0.000
K38.2 Diverticulum of appendix	0.002	0.997	0.000
K38.0 Hyperplasia of appendix	0.002	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.997	0.003
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.997	0.000
K38.9 Disease of appendix, unspecified	0.002	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.998	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
O02 Other abnormal products of conception	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
N64.1 Fat necrosis of breast	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
M79.62 Pain in limb (Upper arm)	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.002	0.998	0.000
S22.8 Fracture of other parts of bony thorax	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
D72.1 Eosinophilia	0.000	0.998	0.002
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
O42 Premature rupture of membranes	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.998	0.002
S22.3 Fracture of rib	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.998	0.000
H40.1 Primary open-angle glaucoma	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.002	0.998	0.000
K02 Dental caries	0.001	0.998	0.002
R54 Senility	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
S22.51 Flail chest (open)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.998	0.002
D74.8 Other methaemoglobinaemias	0.000	0.998	0.002
D74.0 Congenital methaemoglobinaemia	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
H13.3 Ocular pemphigoid	0.002	0.998	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
R27.8 Other and unspecified lack of coordination	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.001	0.998	0.001
K04.4 Acute apical periodontitis of pulpal origin	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations