TreeWAS – Variant ID: rs17594526

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H18.5 Hereditary corneal dystrophies	0.779	0.221	0.000
H18 Other disorders of cornea	0.770	0.230	0.000
H30-H36 Disorders of choroid and retina	0.763	0.237	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.762	0.238	0.000
H35 Other retinal disorders	0.762	0.238	0.000
Chapter VII Diseases of the eye and adnexa	0.760	0.240	0.000
H35.3 Degeneration of macula and posterior pole	0.725	0.275	0.000
H35.8 Other specified retinal disorders	0.723	0.277	0.000
H25-H28 Disorders of lens	0.697	0.303	0.000
H34 Retinal vascular occlusions	0.672	0.328	0.000
H35.6 Retinal haemorrhage	0.645	0.355	0.000
H26 Other cataract	0.643	0.357	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.640	0.360	0.000
H33 Retinal detachments and breaks	0.619	0.381	0.000
H55-H59 Other disorders of eye and adnexa	0.618	0.382	0.000
H31 Other disorders of choroid	0.600	0.400	0.000
H35.2 Other proliferative retinopathy	0.595	0.405	0.000
H35.5 Hereditary retinal dystrophy	0.591	0.408	0.000
H35.7 Separation of retinal layers	0.591	0.409	0.000
H18.8 Other specified disorders of cornea	0.583	0.417	0.000
H10-H13 Disorders of conjunctiva	0.580	0.420	0.000
H18.4 Corneal degeneration	0.575	0.425	0.000
H35.9 Retinal disorder, unspecified	0.566	0.434	0.000
H34.8 Other retinal vascular occlusions	0.566	0.434	0.000
H26.9 Cataract, unspecified	0.564	0.436	0.000
H33.2 Serous retinal detachment	0.563	0.437	0.000
H18.9 Disorder of cornea, unspecified	0.552	0.448	0.000
H18.7 Other corneal deformities	0.552	0.448	0.000
H18.6 Keratoconus	0.552	0.448	0.000
H18.3 Changes in corneal membranes	0.552	0.448	0.000
H18.2 Other corneal oedema	0.552	0.448	0.000
H18.1 Bullous keratopathy	0.552	0.448	0.000
H18.0 Corneal pigmentations and deposits	0.552	0.448	0.000
H34.1 Central retinal artery occlusion	0.548	0.451	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.547	0.453	0.000
H30 Chorioretinal inflammation	0.547	0.453	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.547	0.453	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.547	0.453	0.000
H17 Corneal scars and opacities	0.547	0.453	0.000
H15 Disorders of sclera	0.547	0.453	0.000
H35.1 Retinopathy of prematurity	0.546	0.454	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.545	0.455	0.000
H27 Other disorders of lens	0.536	0.464	0.000
H50 Other strabismus	0.532	0.468	0.000
H16 Keratitis	0.531	0.469	0.000
H43-H45 Disorders of vitreous body and globe	0.528	0.472	0.000
H21 Other disorders of iris and ciliary body	0.524	0.476	0.000
H49 Paralytic strabismus	0.521	0.479	0.000
H26.2 Complicated cataract	0.521	0.479	0.000
H20 Iridocyclitis	0.514	0.486	0.000
H35.0 Background retinopathy and retinal vascular changes	0.504	0.495	0.000
H40-H42 Glaucoma	0.501	0.499	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.500	0.500	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.499	0.501	0.000
H25 Senile cataract	0.498	0.502	0.000
H26.8 Other specified cataract	0.492	0.507	0.000
H34.2 Other retinal artery occlusions	0.489	0.511	0.000
H26.4 After-cataract	0.483	0.516	0.000
H31.8 Other specified disorders of choroid	0.483	0.517	0.000
H55 Nystagmus and other irregular eye movements	0.482	0.518	0.000
H34.9 Retinal vascular occlusion, unspecified	0.481	0.518	0.000
H34.0 Transient retinal artery occlusion	0.481	0.518	0.000
H33.1 Retinoschisis and retinal cysts	0.478	0.522	0.000
H11 Other disorders of conjunctiva	0.477	0.523	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.462	0.538	0.000
H26.3 Drug-induced cataract	0.461	0.539	0.000
H26.1 Traumatic cataract	0.461	0.539	0.000
H26.0 Infantile, juvenile and presenile cataract	0.461	0.539	0.000
H51 Other disorders of binocular movement	0.459	0.541	0.000
H50.9 Strabismus, unspecified	0.456	0.544	0.000
H25.1 Senile nuclear cataract	0.448	0.552	0.000
H36 Retinal disorders in diseases classified elsewhere	0.446	0.554	0.000
H33.4 Traction detachment of retina	0.444	0.556	0.000
H35.4 Peripheral retinal degeneration	0.441	0.558	0.000
H33.5 Other retinal detachments	0.441	0.559	0.000
H49.0 Third [oculomotor] nerve palsy	0.436	0.563	0.000
H31.9 Disorder of choroid, unspecified	0.430	0.569	0.000
H31.4 Choroidal detachment	0.430	0.569	0.000
H31.3 Choroidal haemorrhage and rupture	0.430	0.569	0.000
H31.2 Hereditary choroidal dystrophy	0.430	0.569	0.000
H31.1 Choroidal degeneration	0.430	0.569	0.000
H31.0 Chorioretinal scars	0.430	0.569	0.000
H52 Disorders of refraction and accommodation	0.420	0.580	0.000
H27.0 Aphakia	0.420	0.580	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.416	0.584	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.414	0.586	0.000
H11.3 Conjunctival haemorrhage	0.405	0.595	0.000
H57 Other disorders of eye and adnexa	0.403	0.597	0.000
H30.9 Chorioretinal inflammation, unspecified	0.392	0.607	0.000
H30.8 Other chorioretinal inflammations	0.392	0.607	0.000
H30.2 Posterior cyclitis	0.392	0.607	0.000
H30.1 Disseminated chorioretinal inflammation	0.392	0.607	0.000
H30.0 Focal chorioretinal inflammation	0.392	0.607	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.392	0.607	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.392	0.607	0.000
H15.9 Disorder of sclera, unspecified	0.392	0.608	0.000
H15.8 Other disorders of sclera	0.392	0.608	0.000
H15.1 Episcleritis	0.392	0.608	0.000
H15.0 Scleritis	0.392	0.608	0.000
H17.9 Corneal scar and opacity, unspecified	0.392	0.608	0.000
H17.8 Other corneal scars and opacities	0.392	0.608	0.000
H17.1 Other central corneal opacity	0.392	0.608	0.000
H17.0 Adherent leukoma	0.392	0.608	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.392	0.608	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.392	0.608	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.392	0.608	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.392	0.608	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.392	0.608	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.392	0.608	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.392	0.608	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.392	0.608	0.000
H46 Optic neuritis	0.392	0.608	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.391	0.609	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.391	0.609	0.000
H50.1 Divergent concomitant strabismus	0.387	0.613	0.000
H27.9 Disorder of lens, unspecified	0.384	0.616	0.000
H27.8 Other specified disorders of lens	0.384	0.616	0.000
H27.1 Dislocation of lens	0.384	0.616	0.000
H50.8 Other specified strabismus	0.381	0.619	0.000
H50.6 Mechanical strabismus	0.381	0.619	0.000
H50.5 Heterophoria	0.381	0.619	0.000
H50.4 Other and unspecified heterotropia	0.381	0.619	0.000
H50.3 Intermittent heterotropia	0.381	0.619	0.000
H50.2 Vertical strabismus	0.381	0.619	0.000
H16.9 Keratitis, unspecified	0.381	0.619	0.000
H16.8 Other keratitis	0.381	0.619	0.000
H16.4 Corneal neovascularisation	0.381	0.619	0.000
H16.3 Interstitial and deep keratitis	0.381	0.619	0.000
H16.2 Keratoconjunctivitis	0.381	0.619	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.381	0.619	0.000
H44 Disorders of globe	0.380	0.620	0.000
H11.0 Pterygium	0.380	0.620	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.379	0.621	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.375	0.624	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.375	0.624	0.000
H21.4 Pupillary membranes	0.375	0.624	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.375	0.624	0.000
H21.2 Degeneration of iris and ciliary body	0.375	0.624	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.375	0.624	0.000
H21.0 Hyphaema	0.375	0.624	0.000
H33.3 Retinal breaks without detachment	0.376	0.624	0.000
H10 Conjunctivitis	0.375	0.625	0.000
H49.9 Paralytic strabismus, unspecified	0.374	0.626	0.000
H49.8 Other paralytic strabismus	0.374	0.626	0.000
H49.4 Progressive external ophthalmoplegia	0.374	0.626	0.000
H49.3 Total (external) ophthalmoplegia	0.374	0.626	0.000
H49.2 Sixth [abducent] nerve palsy	0.374	0.626	0.000
H49.1 Fourth [trochlear] nerve palsy	0.374	0.626	0.000
H50.0 Convergent concomitant strabismus	0.373	0.627	0.000
H25.0 Senile incipient cataract	0.371	0.629	0.000
H20.8 Other iridocyclitis	0.369	0.631	0.000
H20.2 Lens-induced iridocyclitis	0.369	0.631	0.000
H20.1 Chronic iridocyclitis	0.369	0.631	0.000
H20.0 Acute and subacute iridocyclitis	0.369	0.631	0.000
H16.0 Corneal ulcer	0.366	0.634	0.000
H43 Disorders of vitreous body	0.361	0.639	0.000
H42 Glaucoma in diseases classified elsewhere	0.359	0.640	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.358	0.641	0.000
H28.2 Cataract in other diseases classified elsewhere	0.358	0.641	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.358	0.641	0.000
H28.0 Diabetic cataract	0.358	0.641	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.358	0.642	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.358	0.642	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.358	0.642	0.000
H25.2 Senile cataract, morgagnian type	0.357	0.643	0.000
H21.8 Other specified disorders of iris and ciliary body	0.353	0.647	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.351	0.649	0.000
H11.9 Disorder of conjunctiva, unspecified	0.342	0.658	0.000
H11.8 Other specified disorders of conjunctiva	0.342	0.658	0.000
H11.2 Conjunctival scars	0.342	0.658	0.000
H11.1 Conjunctival degenerations and deposits	0.342	0.658	0.000
H33.0 Retinal detachment with retinal break	0.337	0.663	0.000
H20.9 Iridocyclitis, unspecified	0.336	0.663	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.331	0.668	0.000
H59.0 Vitreous syndrome following cataract surgery	0.331	0.668	0.000
H51.9 Disorder of binocular movement, unspecified	0.329	0.671	0.000
H51.8 Other specified disorders of binocular movement	0.329	0.671	0.000
H51.2 Internuclear ophthalmoplegia	0.329	0.671	0.000
H51.1 Convergence insufficiency and excess	0.329	0.671	0.000
H51.0 Palsy of conjugate gaze	0.329	0.671	0.000
H52.1 Myopia	0.323	0.677	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.320	0.680	0.000
H40 Glaucoma	0.316	0.684	0.000
H43.3 Other vitreous opacities	0.311	0.689	0.000
H52.7 Disorder of refraction, unspecified	0.301	0.699	0.000
H52.6 Other disorders of refraction	0.301	0.699	0.000
H52.5 Disorders of accommodation	0.301	0.699	0.000
H52.4 Presbyopia	0.301	0.699	0.000
H53-H54 Visual disturbances and blindness	0.300	0.700	0.000
H52.2 Astigmatism	0.299	0.701	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.298	0.702	0.000
H13.3 Ocular pemphigoid	0.298	0.702	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.298	0.702	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.298	0.702	0.000
H13.0 Filarial infection of conjunctiva	0.298	0.702	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.295	0.705	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.291	0.709	0.000
H57.8 Other specified disorders of eye and adnexa	0.290	0.710	0.000
H57.0 Anomalies of pupillary function	0.289	0.711	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.285	0.715	0.000
H25.9 Senile cataract, unspecified	0.283	0.717	0.000
H47.7 Disorder of visual pathways, unspecified	0.280	0.719	0.000
H47.6 Disorders of visual cortex	0.280	0.719	0.000
H47.5 Disorders of other visual pathways	0.280	0.719	0.000
H47.4 Disorders of optic chiasm	0.280	0.719	0.000
H47.3 Other disorders of optic disk	0.280	0.719	0.000
H47.2 Optic atrophy	0.280	0.719	0.000
H47.1 Papilloedema, unspecified	0.280	0.719	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.280	0.719	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.280	0.719	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.280	0.719	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.280	0.719	0.000
H52.3 Anisometropia and aniseikonia	0.274	0.726	0.000
H44.2 Degenerative myopia	0.273	0.727	0.000
H44.9 Disorder of globe, unspecified	0.272	0.728	0.000
H44.8 Other disorders of globe	0.272	0.728	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.272	0.728	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.272	0.728	0.000
H44.5 Degenerated conditions of globe	0.272	0.728	0.000
H44.4 Hypotony of eye	0.272	0.728	0.000
H44.3 Other degenerative disorders of globe	0.272	0.728	0.000
H44.1 Other endophthalmitis	0.272	0.728	0.000
H44.0 Purulent endophthalmitis	0.272	0.728	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.271	0.728	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.271	0.728	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.271	0.728	0.000
H10.8 Other conjunctivitis	0.269	0.731	0.000
H10.5 Blepharoconjunctivitis	0.269	0.731	0.000
H10.4 Chronic conjunctivitis	0.269	0.731	0.000
H10.3 Acute conjunctivitis, unspecified	0.269	0.731	0.000
H10.2 Other acute conjunctivitis	0.269	0.731	0.000
H10.1 Acute atopic conjunctivitis	0.269	0.731	0.000
H10.0 Mucopurulent conjunctivitis	0.269	0.731	0.000
H40.8 Other glaucoma	0.268	0.732	0.000
H52.0 Hypermetropia	0.265	0.735	0.000
H43.9 Disorder of vitreous body, unspecified	0.259	0.741	0.000
H43.2 Crystalline deposits in vitreous body	0.259	0.741	0.000
H43.0 Vitreous prolapse	0.259	0.741	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.258	0.742	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.258	0.742	0.000
H40.5 Glaucoma secondary to other eye disorders	0.256	0.744	0.000
H57.1 Ocular pain	0.239	0.760	0.000
H01 Other inflammation of eyelid	0.239	0.760	0.000
H40.2 Primary angle-closure glaucoma	0.233	0.767	0.000
H10.9 Conjunctivitis, unspecified	0.228	0.771	0.000
H40.6 Glaucoma secondary to drugs	0.227	0.773	0.000
H40.4 Glaucoma secondary to eye inflammation	0.227	0.773	0.000
H40.3 Glaucoma secondary to eye trauma	0.227	0.773	0.000
H36.0 Diabetic retinopathy	0.218	0.782	0.000
H05 Disorders of orbit	0.213	0.787	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.211	0.788	0.000
H25.8 Other senile cataract	0.211	0.789	0.000
H43.1 Vitreous haemorrhage	0.210	0.789	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.209	0.791	0.000
H01.0 Blepharitis	0.202	0.798	0.000
H43.8 Other disorders of vitreous body	0.196	0.804	0.000
H00 Hordeolum and chalazion	0.191	0.808	0.001
H40.9 Glaucoma, unspecified	0.188	0.812	0.000
H01.9 Inflammation of eyelid, unspecified	0.172	0.828	0.000
H01.8 Other specified inflammation of eyelid	0.172	0.828	0.000
H01.1 Non-infectious dermatoses of eyelid	0.172	0.828	0.000
H40.0 Glaucoma suspect	0.172	0.828	0.000
H54 Blindness and low vision	0.168	0.832	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.167	0.832	0.000
H05.0 Acute inflammation of orbit	0.157	0.843	0.000
H06.2 Dysthyroid exophthalmos	0.154	0.845	0.000
H05.9 Disorder of orbit, unspecified	0.153	0.847	0.000
H05.8 Other disorders of orbit	0.153	0.847	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.153	0.847	0.000
H05.4 Enophthalmos	0.153	0.847	0.000
H05.3 Deformity of orbit	0.153	0.847	0.000
H05.2 Exophthalmic conditions	0.153	0.847	0.000
H05.1 Chronic inflammatory disorders of orbit	0.153	0.847	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.152	0.848	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.152	0.848	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.152	0.848	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.150	0.850	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.150	0.850	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.150	0.850	0.000
H40.1 Primary open-angle glaucoma	0.147	0.853	0.000
H04 Disorders of lachrymal system	0.142	0.857	0.000
H54.4 Blindness, one eye	0.122	0.878	0.000
H54.6 Unqualified visual loss, one eye	0.120	0.879	0.000
H54.5 Low vision, one eye	0.120	0.879	0.000
H54.3 Unqualified visual loss, both eyes	0.120	0.879	0.000
H54.2 Low vision, both eyes	0.120	0.879	0.000
H54.1 Blindness, one eye, low vision, other eye	0.120	0.879	0.000
H04.4 Chronic inflammation of lachrymal passages	0.114	0.886	0.000
H54.0 Blindness, both eyes	0.113	0.887	0.000
H54.7 Unspecified visual loss	0.107	0.893	0.000
H04.1 Other disorders of lachrymal gland	0.104	0.895	0.000
H54.9 Unspecified visual impairment (binocular)	0.103	0.897	0.000
H04.9 Disorder of lachrymal system, unspecified	0.102	0.897	0.000
H04.8 Other disorders of lachrymal system	0.102	0.897	0.000
H04.6 Other changes in lachrymal passages	0.102	0.897	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.102	0.897	0.000
H04.0 Dacryoadenitis	0.102	0.897	0.000
H53 Visual disturbances	0.089	0.911	0.000
H04.2 Epiphora	0.067	0.933	0.000
H53.9 Visual disturbance, unspecified	0.065	0.935	0.000
H53.6 Night blindness	0.064	0.936	0.000
H53.5 Colour vision deficiencies	0.064	0.936	0.000
H53.3 Other disorders of binocular vision	0.064	0.936	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.059	0.941	0.000
H53.4 Visual field defects	0.057	0.942	0.000
H53.8 Other visual disturbances	0.052	0.948	0.000
H53.1 Subjective visual disturbances	0.052	0.948	0.000
H53.2 Diplopia	0.051	0.949	0.000
S20-S29 Injuries to the thorax	0.051	0.949	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.050	0.950	0.000
H53.0 Amblyopia ex anopsia	0.049	0.950	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.049	0.951	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.048	0.952	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.048	0.952	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.046	0.954	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.045	0.955	0.000
S22.4 Multiple fractures of ribs	0.045	0.955	0.000
S20 Superficial injury of thorax	0.045	0.955	0.000
S40-S49 Injuries to the shoulder and upper arm	0.045	0.955	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.043	0.957	0.000
S22.40 Multiple fractures of ribs (closed)	0.043	0.957	0.000
S80-S89 Injuries to the knee and lower leg	0.042	0.958	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.042	0.958	0.000
S42 Fracture of shoulder and upper arm	0.041	0.959	0.000
T79-T79 Certain early complications of trauma	0.041	0.959	0.000
S27 Injury of other and unspecified intrathoracic organs	0.040	0.959	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.040	0.960	0.000
T86 Failure and rejection of transplanted organs and tissues	0.040	0.960	0.000
T91 Sequelae of injuries of neck and trunk	0.040	0.960	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.039	0.961	0.000
S50-S59 Injuries to the elbow and forearm	0.039	0.961	0.000
S22.5 Flail chest	0.039	0.961	0.000
T66-T78 Other and unspecified effects of external causes	0.039	0.961	0.000
S10-S19 Injuries to the neck	0.039	0.961	0.000
S70-S79 Injuries to the hip and thigh	0.038	0.962	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.038	0.962	0.000
S22.3 Fracture of rib	0.038	0.962	0.000
S42.0 Fracture of clavicle	0.038	0.962	0.000
S22.1 Multiple fractures of thoracic spine	0.038	0.962	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.038	0.962	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.038	0.962	0.000
S20.2 Contusion of thorax	0.037	0.963	0.000
S80 Superficial injury of lower leg	0.037	0.963	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.037	0.963	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.036	0.963	0.000
S26 Injury of heart	0.036	0.963	0.000
S25 Injury of blood vessels of thorax	0.036	0.963	0.000
S24 Injury of nerves and spinal cord at thorax level	0.036	0.963	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.036	0.963	0.000
S21 Open wound of thorax	0.036	0.963	0.000
S22.0 Fracture of thoracic vertebra	0.036	0.964	0.000
T90 Sequelae of injuries of head	0.036	0.964	0.000
T33-T35 Frostbite	0.036	0.964	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.036	0.964	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.036	0.964	0.000
T00-T07 Injuries involving multiple body regions	0.036	0.964	0.000
T93 Sequelae of injuries of lower limb	0.036	0.964	0.000
S42.1 Fracture of scapula	0.036	0.964	0.000
S42.00 Fracture of clavicle (closed)	0.036	0.964	0.000
S29 Other and unspecified injuries of thorax	0.035	0.964	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.035	0.964	0.000
T82.1 Mechanical complication of cardiac electronic device	0.035	0.965	0.000
T87 Complications peculiar to reattachment and amputation	0.035	0.965	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.035	0.965	0.000
S22.9 Fracture of bony thorax, part unspecified	0.035	0.965	0.000
S22.8 Fracture of other parts of bony thorax	0.035	0.965	0.000
T98 Sequelae of other and unspecified effects of external causes	0.035	0.965	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.035	0.965	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.035	0.965	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.035	0.965	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.035	0.965	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.035	0.965	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.035	0.965	0.000
T82.3 Mechanical complication of other vascular grafts	0.035	0.965	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.035	0.965	0.000
S90-S99 Injuries to the ankle and foot	0.035	0.965	0.000
T18 Foreign body in alimentary tract	0.034	0.966	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.034	0.966	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.034	0.966	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.034	0.966	0.000
T91.3 Sequelae of injury of spinal cord	0.034	0.966	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.034	0.966	0.000
T86.0 Bone-marrow transplant rejection	0.033	0.967	0.000
S22.2 Fracture of sternum	0.033	0.967	0.000
S80.0 Contusion of knee	0.033	0.967	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.033	0.967	0.000
T17 Foreign body in respiratory tract	0.033	0.967	0.000
T95 Sequelae of burns, corrosions and frostbite	0.033	0.967	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.033	0.967	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.033	0.967	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.033	0.967	0.000
S22.41 Multiple fractures of ribs (open)	0.032	0.967	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.032	0.967	0.000
S22.50 Flail chest (closed)	0.032	0.968	0.000
S20.7 Multiple superficial injuries of thorax	0.032	0.968	0.000
S20.4 Other superficial injuries of back wall of thorax	0.032	0.968	0.000
S20.3 Other superficial injuries of front wall of thorax	0.032	0.968	0.000
S20.1 Other and unspecified superficial injuries of breast	0.032	0.968	0.000
S20.0 Contusion of breast	0.032	0.968	0.000
S40 Superficial injury of shoulder and upper arm	0.032	0.968	0.000
S48 Traumatic amputation of shoulder and upper arm	0.032	0.968	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.032	0.968	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.032	0.968	0.000
S44 Injury of nerves at shoulder and upper arm level	0.032	0.968	0.000
S41 Open wound of shoulder and upper arm	0.032	0.968	0.000
S47 Crushing injury of shoulder and upper arm	0.032	0.968	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.032	0.968	0.000
S42.10 Fracture of scapula (closed)	0.032	0.968	0.000
T91.1 Sequelae of fracture of spine	0.032	0.968	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.032	0.968	0.000
S52 Fracture of forearm	0.032	0.968	0.000
H00.1 Chalazion	0.030	0.968	0.002
S72 Fracture of femur	0.032	0.968	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.032	0.968	0.000
S83.2 Tear of meniscus, current	0.031	0.969	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.031	0.969	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.031	0.969	0.000
T83.2 Mechanical complication of graft of urinary organ	0.031	0.969	0.000
S27.3 Other injuries of lung	0.031	0.969	0.000
S27.1 Traumatic haemothorax	0.031	0.969	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.031	0.969	0.000
T68 Hypothermia	0.031	0.969	0.000
S12 Fracture of neck	0.031	0.969	0.000
S88 Traumatic amputation of lower leg	0.030	0.969	0.000
S87 Crushing injury of lower leg	0.030	0.969	0.000
S86 Injury of muscle and tendon at lower leg level	0.030	0.969	0.000
S85 Injury of blood vessels at lower leg level	0.030	0.969	0.000
S84 Injury of nerves at lower leg level	0.030	0.969	0.000
S89 Other and unspecified injuries of lower leg	0.030	0.969	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.030	0.969	0.000
S27.2 Traumatic heamopneumothorax	0.030	0.970	0.000
T86.1 Kidney transplant failure and rejection	0.030	0.970	0.000
S22.30 Fracture of rib (closed)	0.030	0.970	0.000
T19 Foreign body in genito-urinary tract	0.030	0.970	0.000
T15 Foreign body on external eye	0.030	0.970	0.000
T16 Foreign body in ear	0.030	0.970	0.000
T13 Other injuries of lower limb, level unspecified	0.030	0.970	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.030	0.970	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.030	0.970	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.030	0.970	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.030	0.970	0.000
S51 Open wound of forearm	0.030	0.970	0.000
S42.3 Fracture of shaft of humerus	0.030	0.970	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.030	0.970	0.000
S71 Open wound of hip and thigh	0.029	0.970	0.000
T79.6 Traumatic ischaemia of muscle	0.029	0.970	0.000
S27.9 Injury of unspecified intrathoracic organ	0.029	0.971	0.000
S27.8 Injury of other specified intrathoracic organs	0.029	0.971	0.000
S27.7 Multiple injuries of intrathoracic organs	0.029	0.971	0.000
S27.6 Injury of pleura	0.029	0.971	0.000
S27.5 Injury of thoracic trachea	0.029	0.971	0.000
S27.4 Injury of bronchus	0.029	0.971	0.000
T93.2 Sequelae of other fractures of lower limb	0.029	0.971	0.000
S27.0 Traumatic pneumothorax	0.029	0.971	0.000
S42.4 Fracture of lower end of humerus	0.029	0.971	0.000
T78 Adverse effects, not elsewhere classified	0.029	0.971	0.000
S80.8 Other superficial injuries of lower leg	0.029	0.971	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.029	0.971	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.029	0.971	0.000
T86.4 Liver transplant failure and rejection	0.029	0.971	0.000
T86.3 Heart-lung transplant failure and rejection	0.029	0.971	0.000
T86.2 Heart transplant failure and rejection	0.029	0.971	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.029	0.971	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.029	0.971	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.029	0.971	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.029	0.971	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.029	0.971	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.029	0.971	0.000
T18.1 Foreign body in oesophagus	0.029	0.971	0.000
T92 Sequelae of injuries of upper limb	0.028	0.971	0.000
T90.9 Sequelae of unspecified injury of head	0.028	0.971	0.000
S59 Other and unspecified injuries of forearm	0.028	0.972	0.000
S58 Traumatic amputation of forearm	0.028	0.972	0.000
S57 Crushing injury of forearm	0.028	0.972	0.000
S56 Injury of muscle and tendon at forearm level	0.028	0.972	0.000
S55 Injury of blood vessels at forearm level	0.028	0.972	0.000
S54 Injury of nerves at forearm level	0.028	0.972	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.028	0.972	0.000
S22.51 Flail chest (open)	0.028	0.972	0.000
T75 Effects of other external causes	0.028	0.972	0.000
T74 Maltreatment syndromes	0.028	0.972	0.000
T73 Effects of other deprivation	0.028	0.972	0.000
T70 Effects of air pressure and water pressure	0.028	0.972	0.000
T69 Other effects of reduced temperature	0.028	0.972	0.000
T67 Effects of heat and light	0.028	0.972	0.000
T71 Asphyxiation	0.028	0.972	0.000
T66 Unspecified effects of radiation	0.028	0.972	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.028	0.972	0.000
S19 Other and unspecified injuries of neck	0.028	0.972	0.000
S17 Crushing injury of neck	0.028	0.972	0.000
S15 Injury of blood vessels at neck level	0.028	0.972	0.000
S14 Injury of nerves and spinal cord at neck level	0.028	0.972	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.028	0.972	0.000
S11 Open wound of neck	0.028	0.972	0.000
S10 Superficial injury of neck	0.028	0.972	0.000
S18 Traumatic amputation at neck level	0.028	0.972	0.000
S16 Injury of muscle and tendon at neck level	0.028	0.972	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.028	0.972	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.028	0.972	0.000
S78 Traumatic amputation of hip and thigh	0.028	0.972	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations