TreeWAS – Variant ID: rs17608902

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.045	0.955	0.000
Z50.1 Other physical therapy	0.000	0.967	0.033
I10-I15 Hypertensive diseases	0.029	0.971	0.000
I11 Hypertensive heart disease	0.028	0.972	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.026	0.974	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.977	0.023
I11.9 Hypertensive heart disease without (congestive) heart failure	0.023	0.977	0.000
Z50 Care involving use of rehabilitation procedures	0.000	0.978	0.022
I13 Hypertensive heart and renal disease	0.021	0.979	0.000
I15 Secondary hypertension	0.020	0.980	0.000
I12 Hypertensive renal disease	0.019	0.981	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.981	0.019
Z50.6 Orthoptic training	0.000	0.984	0.016
Z50.3 Drug rehabilitation	0.000	0.984	0.016
I13.9 Hypertensive heart and renal disease, unspecified	0.015	0.984	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.015	0.984	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.015	0.984	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.015	0.984	0.000
Z50.5 Speech therapy	0.000	0.985	0.015
I12.9 Hypertensive renal disease without renal failure	0.015	0.985	0.000
I15.9 Seconday hypertension, unspecified	0.015	0.985	0.000
I15.8 Other secondary hypertension	0.014	0.985	0.000
I15.2 Hypertension secondary to endocrine disorders	0.014	0.985	0.000
I15.0 Renovascular hypertension	0.014	0.985	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.986	0.014
I15.1 Hypertension secondary to other renal disorders	0.012	0.987	0.000
Z50.2 Alcohol rehabilitation	0.000	0.988	0.012
Z50.0 Cardiac rehabilitation	0.000	0.990	0.010
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.990	0.010
I12.0 Hypertensive renal disease with renal failure	0.009	0.991	0.000
T43.2 Other and unspecified antidepressants	0.000	0.991	0.009
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.992	0.008
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.992	0.008
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.993	0.007
I65.2 Occlusion and stenosis of carotid artery	0.007	0.993	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.994	0.006
T43.9 Psychotropic drug, unspecified	0.000	0.994	0.006
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.994	0.006
Z13.9 Special screening examination, unspecified	0.006	0.994	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.994	0.006
F05.9 Delirium, unspecified	0.006	0.994	0.000
S02.2 Fracture of nasal bones	0.000	0.994	0.005
S02.4 Fracture of malar and maxillary bones	0.000	0.995	0.005
S02 Fracture of skull and facial bones	0.000	0.995	0.005
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.995	0.005
S02.1 Fracture of base of skull	0.000	0.995	0.005
S02.8 Fractures of other skull and facial bones	0.000	0.995	0.005
S02.10 Fracture of base of skull (closed)	0.000	0.995	0.005
S02.3 Fracture of orbital floor	0.000	0.995	0.005
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.005	0.995	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.995	0.005
S02.30 Fracture of orbital floor (closed)	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.996	0.004
S02.5 Fracture of tooth	0.000	0.996	0.004
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.996	0.004
S02.7 Multiple fractures involving skull and facial bones	0.000	0.996	0.004
S02.0 Fracture of vault of skull	0.000	0.996	0.004
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.996	0.004
S02.11 Fracture of base of skull (open)	0.000	0.996	0.004
S02.81 Fractures of other skull and facial bones (open)	0.000	0.996	0.004
S02.31 Fracture of orbital floor (open)	0.000	0.996	0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.003	0.996	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.003	0.996	0.000
I65.1 Occlusion and stenosis of basilar artery	0.003	0.996	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.003	0.996	0.000
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
Y40.0 Penicillins	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
S02.51 Fracture of tooth (open)	0.000	0.997	0.003
S02.6 Fracture of mandible	0.000	0.997	0.003
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.997	0.003
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.997	0.003
D04.7 Skin of lower limb, including hip	0.003	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.997	0.003
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.997	0.003
Y40 Systemic antibiotics	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.000	0.997	0.003
Z42.1 Follow-up care involving plastic surgery of breast	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
T42.4 Benzodiazepines	0.000	0.997	0.003
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
C25.9 Pancreas, unspecified	0.000	0.997	0.003
S02.61 Fracture of mandible (open)	0.000	0.997	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
F05.0 Delirium not superimposed on dementia, so described	0.002	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.997	0.002
Y40.6 Rifamycins	0.000	0.997	0.002
Y40.5 Aminoglycosides	0.000	0.997	0.002
Y40.4 Tetracyclines	0.000	0.997	0.002
Y40.2 Chloramphenicol group	0.000	0.997	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.002
Z42 Follow-up care involving plastic surgery	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.002
T40.8 Lysergide [LSD]	0.000	0.997	0.002
T40.7 Cannabis (derivatives)	0.000	0.997	0.002
T40.5 Cocaine	0.000	0.997	0.002
T40.3 Methadone	0.000	0.997	0.002
T40.1 Heroin	0.000	0.997	0.002
T40.0 Opium	0.000	0.997	0.002
Y40.3 Macrolides	0.000	0.997	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.002
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
G57.6 Lesion of plantar nerve	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.002	0.998	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.002	0.998	0.000
C25.0 Head of pancreas	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
N89.5 Stricture and atresia of vagina	0.000	0.998	0.002
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
N89 Other noninflammatory disorders of vagina	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.001
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
I08 Multiple valve diseases	0.002	0.998	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.002	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.001	0.998	0.001
D04.5 Skin of trunk	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.002	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
N89.6 Tight hymenal ring	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.001	0.998	0.001
T78.3 Angioneurotic oedema	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
N89.7 Haematocolpos	0.000	0.998	0.002
N89.4 Leukoplakia of vagina	0.000	0.998	0.002
N89.3 Dysplasia of vagina, unspecified	0.000	0.998	0.002
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.998	0.002
N89.1 Moderate vaginal dysplasia	0.000	0.998	0.002
N89.0 Mild vaginal dysplasia	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.001
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.001
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.001
I08.9 Multiple valve disease, unspecified	0.001	0.998	0.000
N81.5 Vaginal enterocele	0.000	0.998	0.002
H50.5 Heterophoria	0.001	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
H50.2 Vertical strabismus	0.001	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.998	0.000
Q66 Congenital deformities of feet	0.001	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.001
C25.7 Other parts of pancreas	0.000	0.998	0.001
C25.4 Endocrine pancreas	0.000	0.998	0.001
C25.3 Pancreatic duct	0.000	0.998	0.001
C25.1 Body of pancreas	0.000	0.998	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Q66.2 Metatarsus varus	0.001	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.001
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.001	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
H50.8 Other specified strabismus	0.001	0.998	0.000
H50.6 Mechanical strabismus	0.001	0.998	0.000
H50.4 Other and unspecified heterotropia	0.001	0.998	0.000
H50.3 Intermittent heterotropia	0.001	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.001	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.998	0.000
Q79.4 Prune belly syndrome	0.001	0.998	0.000
Q79.3 Gastroschisis	0.001	0.998	0.000
Q79.2 Exomphalos	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.998	0.001
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.001	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.998	0.000
Z13.5 Special screening examination for eye and ear disorders	0.001	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.001	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.001	0.999	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.001	0.999	0.000
K04.8 Radicular cyst	0.001	0.999	0.000
M54.9 Dorsalgia, unspecified	0.001	0.999	0.000
D04.3 Skin of other and unspecified parts of face	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.001
C77.9 Lymph node, unspecified	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.999	0.000
K07.3 Anomalies of tooth position	0.001	0.999	0.000
I05-I09 Chronic rheumatic heart diseases	0.001	0.999	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.999	0.001
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.001	0.999	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.44 Lumbago with sciatica-Thoracic	0.001	0.999	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.001	0.999	0.000
M54.42 Lumbago with sciatica-Cervical	0.001	0.999	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.001	0.999	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.001	0.999	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.999	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.999	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.999	0.000
Q78.6 Multiple congenital exostoses	0.001	0.999	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.999	0.000
Q78.4 Enchondromatosis	0.001	0.999	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.999	0.000
Q78.2 Osteopetrosis	0.001	0.999	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.999	0.000
R00.1 Bradycardia, unspecified	0.001	0.999	0.000
Y84.8 Other medical procedures	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000
Q73 Reduction defects of unspecified limb	0.001	0.999	0.000
Q72 Reduction defects of lower limb	0.001	0.999	0.000
Q71 Reduction defects of upper limb	0.001	0.999	0.000
Q70 Syndactyly	0.001	0.999	0.000
Q69 Polydactyly	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000
Z13 Special screening examination for other diseases and disorders	0.001	0.999	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.999	0.001
Q63 Other congenital malformations of kidney	0.001	0.999	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
J94.2 Haemothorax	0.000	0.999	0.001
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.001	0.999	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.999	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.999	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.999	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
Q74.1 Congenital malformation of knee	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.000	0.999	0.001
T78.8 Other adverse effects, not elsewhere classified	0.000	0.999	0.001
M54.92 Dorsalgia, unspecified (Cervical region)	0.001	0.999	0.000
E11.2 With renal complications	0.001	0.999	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.999	0.000
Q76.7 Congenital malformation of sternum	0.001	0.999	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.999	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.001	0.999	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.999	0.000
C25.2 Tail of pancreas	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.001	0.999	0.000
Q63.2 Ectopic kidney	0.001	0.999	0.000
I62 Other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
D00.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
D06.9 Cervix, unspecified	0.001	0.999	0.000
I28.8 Other specified diseases of pulmonary vessels	0.001	0.999	0.000
M20.1 Hallux valgus (acquired)	0.001	0.999	0.000
N94.1 Dyspareunia	0.000	0.999	0.001
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.001	0.999	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
D00.1 Oesophagus	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.001	0.999	0.000
W18.5 Trade and service area	0.001	0.999	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.001	0.999	0.000
I60-I69 Cerebrovascular diseases	0.001	0.999	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
Q67.8 Other congenital deformities of chest	0.001	0.999	0.000
Q67.7 Pectus carinatum	0.001	0.999	0.000
Q67.6 Pectus excavatum	0.001	0.999	0.000
Q67.5 Congenital deformity of spine	0.001	0.999	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.999	0.000
Q67.3 Plagiocephaly	0.001	0.999	0.000
Q67.2 Dolichocephaly	0.001	0.999	0.000
Q67.1 Compression facies	0.001	0.999	0.000
Q67.0 Facial asymmetry	0.001	0.999	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.999	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.999	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.999	0.000
Q68.3 Congenital bowing of femur	0.001	0.999	0.000
Q68.2 Congenital deformity of knee	0.001	0.999	0.000
Q68.1 Congenital deformity of hand	0.001	0.999	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.999	0.000
Q69.9 Polydactyly, unspecified	0.001	0.999	0.000
Q69.2 Accessory toe(s)	0.001	0.999	0.000
Q69.1 Accessory thumb(s)	0.001	0.999	0.000
Q69.0 Accessory finger(s)	0.001	0.999	0.000
Q70.9 Syndactyly, unspecified	0.001	0.999	0.000
Q70.4 Polysyndactyly	0.001	0.999	0.000
Q70.3 Webbed toes	0.001	0.999	0.000
Q70.2 Fused toes	0.001	0.999	0.000
Q70.1 Webbed fingers	0.001	0.999	0.000
Q70.0 Fused fingers	0.001	0.999	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.999	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.999	0.000
Q71.6 Lobster-claw hand	0.001	0.999	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.999	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.999	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.999	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.999	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.999	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.999	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.999	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations