TreeWAS – Variant ID: rs17749211

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.053	0.947	0.000
H72 Perforation of tympanic membrane	0.052	0.948	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.049	0.951	0.000
H74 Other disorders of middle ear and mastoid	0.049	0.951	0.000
H65 Nonsuppurative otitis media	0.048	0.952	0.000
H65.3 Chronic mucoid otitis media	0.048	0.952	0.000
H74.4 Polyp of middle ear	0.046	0.954	0.000
H71 Cholesteatoma of middle ear	0.044	0.956	0.000
H72.0 Central perforation of tympanic membrane	0.043	0.957	0.000
H66 Suppurative and unspecified otitis media	0.042	0.958	0.000
H74.0 Tympanosclerosis	0.041	0.959	0.000
H72.8 Other perforations of tympanic membrane	0.041	0.959	0.000
H69 Other disorders of Eustachian tube	0.040	0.960	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.038	0.962	0.000
H68 Eustachian salpingitis and obstruction	0.038	0.962	0.000
H67 Otitis media in diseases classified elsewhere	0.038	0.962	0.000
H72.2 Other marginal perforations of tympanic membrane	0.037	0.963	0.000
H72.1 Attic perforation of tympanic membrane	0.037	0.963	0.000
H70 Mastoiditis and related conditions	0.037	0.963	0.000
H73 Other disorders of tympanic membrane	0.037	0.963	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.037	0.963	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.036	0.964	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.035	0.965	0.000
H74.1 Adhesive middle ear disease	0.035	0.965	0.000
H66.4 Suppurative otitis media, unspecified	0.035	0.965	0.000
H65.1 Other acute nonsuppurative otitis media	0.035	0.965	0.000
H65.0 Acute serous otitis media	0.035	0.965	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.034	0.966	0.000
H65.2 Chronic serous otitis media	0.033	0.967	0.000
H66.3 Other chronic suppurative otitis media	0.032	0.968	0.000
H69.8 Other specified disorders of Eustachian tube	0.031	0.969	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.030	0.969	0.000
H66.0 Acute suppurative otitis media	0.030	0.969	0.000
H65.4 Other chronic nonsuppurative otitis media	0.029	0.970	0.000
Chapter VIII Diseases of the ear and mastoid process	0.029	0.971	0.000
H69.0 Patulous Eustachian tube	0.029	0.971	0.000
H69.9 Eustachian tube disorder, unspecified	0.029	0.971	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.028	0.971	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.028	0.972	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.027	0.972	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.027	0.972	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.027	0.972	0.000
H68.1 Obstruction of Eustachian tube	0.027	0.972	0.000
H68.0 Eustachian salpingitis	0.027	0.972	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.027	0.972	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.027	0.972	0.000
H70.8 Other mastoiditis and related conditions	0.027	0.973	0.000
H70.2 Petrositis	0.027	0.973	0.000
H70.1 Chronic mastoiditis	0.027	0.973	0.000
H70.0 Acute mastoiditis	0.027	0.973	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.027	0.973	0.000
H73.1 Chronic myringitis	0.027	0.973	0.000
H73.0 Acute myringitis	0.027	0.973	0.000
H70.9 Mastoiditis, unspecified	0.026	0.974	0.000
H73.8 Other specified disorders of tympanic membrane	0.025	0.974	0.000
H60-H62 Diseases of external ear	0.025	0.975	0.000
H80-H83 Diseases of inner ear	0.025	0.975	0.000
H81.0 Meniere's disease	0.023	0.977	0.000
H81 Disorders of vestibular function	0.023	0.977	0.000
H60 Otitis externa	0.022	0.978	0.000
H66.9 Otitis media, unspecified	0.021	0.979	0.000
H60.3 Other infective otitis externa	0.019	0.981	0.000
H83 Other diseases of inner ear	0.018	0.981	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.018	0.982	0.000
H60.8 Other otitis externa	0.018	0.982	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.018	0.982	0.000
H61 Other disorders of external ear	0.018	0.982	0.000
H60.5 Acute otitis externa, non-infective	0.018	0.982	0.000
H60.1 Cellulitis of external ear	0.017	0.983	0.000
H81.9 Disorder of vestibular function, unspecified	0.016	0.983	0.000
H81.8 Other disorders of vestibular function	0.016	0.983	0.000
H81.4 Vertigo of central origin	0.016	0.983	0.000
H81.3 Other peripheral vertigo	0.016	0.983	0.000
H60.4 Cholesteatoma of external ear	0.016	0.984	0.000
H60.2 Malignant otitis externa	0.016	0.984	0.000
H60.0 Abscess of external ear	0.016	0.984	0.000
H80 Otosclerosis	0.015	0.985	0.000
R05 Cough	0.000	0.986	0.014
H81.2 Vestibular neuronitis	0.014	0.986	0.000
H61.2 Impacted cerumen	0.014	0.986	0.000
H90-H95 Other disorders of ear	0.014	0.986	0.000
H61.1 Non-infective disorders of pinna	0.014	0.986	0.000
H83.0 Labyrinthitis	0.014	0.986	0.000
H61.9 Disorder of external ear, unspecified	0.013	0.986	0.000
H83.9 Disease of inner ear, unspecified	0.013	0.986	0.000
H83.8 Other specified diseases of inner ear	0.013	0.986	0.000
H83.3 Noise effects on inner ear	0.013	0.986	0.000
H83.2 Labyrinthine dysfunction	0.013	0.986	0.000
H83.1 Labyrinthine fistula	0.013	0.986	0.000
H81.1 Benign paroxysmal vertigo	0.013	0.987	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.013	0.987	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.013	0.987	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
H62.2 Otitis externa in mycoses	0.013	0.987	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.013	0.987	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.013	0.987	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.987	0.013
H60.9 Otitis externa, unspecified	0.013	0.987	0.000
H61.8 Other specified disorders of external ear	0.012	0.988	0.000
H61.0 Perichondritis of external ear	0.012	0.988	0.000
H61.3 Acquired stenosis of external ear canal	0.011	0.988	0.000
H80.8 Other otosclerosis	0.011	0.989	0.000
H80.2 Cochlear otosclerosis	0.011	0.989	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.011	0.989	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.011	0.989	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.010	0.989	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.011	0.989	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.010	0.990	0.000
H90 Conductive and sensorineural hearing loss	0.010	0.990	0.000
H92 Otalgia and effusion of ear	0.009	0.991	0.000
H93 Other disorders of ear, not elsewhere classified	0.009	0.991	0.000
H80.9 Otosclerosis, unspecified	0.008	0.992	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H95.1 Other disorders following mastoidectomy	0.008	0.992	0.000
H91 Other hearing loss	0.008	0.992	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.008	0.992	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.008	0.992	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.008	0.992	0.000
H92.1 Otorrhoea	0.008	0.992	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.007	0.992	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
H90.3 Sensorineural hearing loss, bilateral	0.007	0.992	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.007	0.993	0.000
H90.0 Conductive hearing loss, bilateral	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.007	0.993	0.000
H92.2 Otorrhagia	0.007	0.993	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H93.8 Other specified disorders of ear	0.007	0.993	0.000
H93.3 Disorders of acoustic nerve	0.007	0.993	0.000
H93.2 Other abnormal auditory perceptions	0.007	0.993	0.000
H93.0 Degenerative and vascular disorders of ear	0.007	0.993	0.000
H93.9 Disorder of ear, unspecified	0.006	0.993	0.000
C15.4 Middle third of oesophagus	0.006	0.994	0.000
H91.3 Deaf mutism, not elsewhere classified	0.006	0.994	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.994	0.006
C15 Malignant neoplasm of oesophagus	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.006	0.994	0.000
H91.2 Sudden idiopathic hearing loss	0.006	0.994	0.000
H91.1 Presbycusis	0.006	0.994	0.000
H91.0 Ototoxic hearing loss	0.006	0.994	0.000
C15.9 Oesophagus, unspecified	0.006	0.994	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.994	0.006
H91.8 Other specified hearing loss	0.006	0.994	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.994	0.000
C77.9 Lymph node, unspecified	0.000	0.994	0.006
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.994	0.006
I51.8 Other ill-defined heart diseases	0.000	0.994	0.006
H93.1 Tinnitus	0.005	0.995	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.995	0.005
C77.8 Lymph nodes of multiple regions	0.000	0.995	0.005
H92.0 Otalgia	0.004	0.995	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.995	0.005
C15.8 Overlapping lesion of oesophagus	0.004	0.995	0.000
C15.3 Upper third of oesophagus	0.004	0.995	0.000
C15.2 Abdominal part of oesophagus	0.004	0.995	0.000
C15.1 Thoracic part of oesophagus	0.004	0.995	0.000
C15.0 Cervical part of oesophagus	0.004	0.995	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.996	0.004
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.996	0.004
K63.9 Disease of intestine, unspecified	0.000	0.996	0.004
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
M79.79 Fibromyalgia (Site unspecified)	0.004	0.996	0.000
L08 Other local infections of skin and subcutaneous tissue	0.000	0.996	0.004
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.996	0.004
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.996	0.003
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.997	0.003
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.003
J18.1 Lobar pneumonia, unspecified	0.003	0.997	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.997	0.003
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.997	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
M79.09 Rheumatism, unspecified (Site unspecified)	0.003	0.997	0.000
L08.1 Erythrasma	0.000	0.997	0.003
L08.0 Pyoderma	0.000	0.997	0.003
S52.00 Fracture of upper end of ulna (closed)	0.003	0.997	0.000
H91.9 Hearing loss, unspecified	0.003	0.997	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.997	0.003
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.997	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
M79.7 Fibromyalgia	0.002	0.998	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
S00.1 Contusion of eyelid and periocular area	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
K63.3 Ulcer of intestine	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.998	0.002
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
M79.70 Fibromyalgia (Multiple sites)	0.002	0.998	0.000
K63 Other diseases of intestine	0.000	0.998	0.002
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.998	0.002
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
M79.78 Fibromyalgia (Other)	0.002	0.998	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.002	0.998	0.000
M79.76 Fibromyalgia (Lower leg)	0.002	0.998	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.002	0.998	0.000
M79.74 Fibromyalgia (Hand)	0.002	0.998	0.000
M79.73 Fibromyalgia (Forearm)	0.002	0.998	0.000
M79.72 Fibromyalgia (Upper arm)	0.002	0.998	0.000
M79.71 Fibromyalgia (Shoulder region)	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
R39.2 Extrarenal uraemia	0.000	0.998	0.002
R39.0 Extravasation of urine	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
L03.2 Cellulitis of face	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
R39.1 Other difficulties with micturition	0.000	0.998	0.002
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
K63.4 Enteroptosis	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
K63.5 Polyp of colon	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
R60.0 Localised oedema	0.000	0.998	0.002
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
K63.0 Abscess of intestine	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
R41.3 Other amnesia	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.998	0.000
Z63.4 Disappearance and death of family member	0.000	0.998	0.002
I08 Multiple valve diseases	0.000	0.998	0.002
M19.03 Primary arthrosis of other joints (Forearm)	0.001	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.998	0.000
H20.8 Other iridocyclitis	0.001	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.001	0.998	0.000
H20.1 Chronic iridocyclitis	0.001	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
C71.7 Brain stem	0.001	0.998	0.000
C71.6 Cerebellum	0.001	0.998	0.000
C71.5 Cerebral ventricle	0.001	0.998	0.000
C71.4 Occipital lobe	0.001	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.001	0.998	0.000
H16.2 Keratoconjunctivitis	0.001	0.998	0.000
H18.7 Other corneal deformities	0.001	0.998	0.000
H18.6 Keratoconus	0.001	0.998	0.000
H18.3 Changes in corneal membranes	0.001	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.001	0.998	0.000
H18.8 Other specified disorders of cornea	0.001	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
J18 Pneumonia, organism unspecified	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.001	0.998	0.000
R41.1 Anterograde amnesia	0.001	0.998	0.000
C71.2 Temporal lobe	0.001	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
S00.7 Multiple superficial injuries of head	0.001	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.001	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.001	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.998	0.000
G47.9 Sleep disorder, unspecified	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.001	0.998	0.000
I31 Other diseases of pericardium	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.001	0.998	0.000
I51.4 Myocarditis, unspecified	0.000	0.998	0.001
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.001
S12.1 Fracture of second cervical vertebra	0.001	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.998	0.000
S10-S19 Injuries to the neck	0.001	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
C16.5 Lesser curvature of stomach, unspecified	0.001	0.999	0.000
H17.8 Other corneal scars and opacities	0.001	0.999	0.000
H17.1 Other central corneal opacity	0.001	0.999	0.000
H17.0 Adherent leukoma	0.001	0.999	0.000
S14.3 Injury of brachial plexus	0.001	0.999	0.000
S32.3 Fracture of ilium	0.001	0.999	0.000
S32.2 Fracture of coccyx	0.001	0.999	0.000
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.999	0.001
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.999	0.000
S31.1 Open wound of abdominal wall	0.001	0.999	0.000
J10 Influenza due to identified influenza virus	0.001	0.999	0.000
R45 Symptoms and signs involving emotional state	0.001	0.999	0.000
H15.9 Disorder of sclera, unspecified	0.001	0.999	0.000
H15.8 Other disorders of sclera	0.001	0.999	0.000
H15.1 Episcleritis	0.001	0.999	0.000
H15.0 Scleritis	0.001	0.999	0.000
H16.8 Other keratitis	0.001	0.999	0.000
H16.4 Corneal neovascularisation	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.999	0.001
I51.6 Cardiovascular disease, unspecified	0.000	0.999	0.001
S22.3 Fracture of rib	0.001	0.999	0.000
S36.0 Injury of spleen	0.001	0.999	0.000
S10 Superficial injury of neck	0.001	0.999	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.999	0.000
H18.4 Corneal degeneration	0.001	0.999	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.999	0.001
I78.1 Naevus, nonneoplastic	0.000	0.999	0.001
S27.9 Injury of unspecified intrathoracic organ	0.001	0.999	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.999	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.999	0.000
S27.6 Injury of pleura	0.001	0.999	0.000
S27.5 Injury of thoracic trachea	0.001	0.999	0.000
S27.4 Injury of bronchus	0.001	0.999	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.001	0.999	0.000
H16.9 Keratitis, unspecified	0.001	0.999	0.000
I51.5 Myocardial degeneration	0.000	0.999	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.999	0.001
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.999	0.001
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.999	0.001
S01.0 Open wound of scalp	0.001	0.999	0.000
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
S22.9 Fracture of bony thorax, part unspecified	0.001	0.999	0.000
S22.8 Fracture of other parts of bony thorax	0.001	0.999	0.000
S22.5 Flail chest	0.001	0.999	0.000
S37.0 Injury of kidney	0.001	0.999	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.001	0.999	0.000
J18.8 Other pneumonia, organism unspecified	0.001	0.999	0.000
J18.2 Hypostatic pneumonia, unspecified	0.001	0.999	0.000
S32.1 Fracture of sacrum	0.001	0.999	0.000
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
R45.2 Unhappiness	0.001	0.999	0.000
R86.8 Other abnormal findings	0.001	0.999	0.000
S14.6 Injury of other and unspecified nerves of neck	0.001	0.999	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.999	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.999	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.999	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.999	0.000
S27.1 Traumatic haemothorax	0.001	0.999	0.000
S36 Injury of intra-abdominal organs	0.001	0.999	0.000
I08.8 Other multiple valve diseases	0.000	0.999	0.001
I31.8 Other specified diseases of pericardium	0.000	0.999	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.999	0.001
I31.1 Chronic constrictive pericarditis	0.000	0.999	0.001
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
L29.0 Pruritus ani	0.000	0.999	0.001
S00.4 Superficial injury of ear	0.001	0.999	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.999	0.000
S31.5 Open wound of other and unspecified external genital organs	0.001	0.999	0.000
S31.4 Open wound of vagina and vulva	0.001	0.999	0.000
S31.3 Open wound of scrotum and testes	0.001	0.999	0.000
S31.2 Open wound of penis	0.001	0.999	0.000
Z00.0 General medical examination	0.000	0.999	0.001
S37 Injury of urinary and pelvic organs	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
R45.1 Restlessness and agitation	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
X51.9 Unspecified place	0.001	0.999	0.000
S00 Superficial injury of head	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
S32.21 Fracture of coccyx (open)	0.001	0.999	0.000
S32.20 Fracture of coccyx (closed)	0.001	0.999	0.000
S32.31 Fracture of ilium (open)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations