TreeWAS – Variant ID: rs1800961

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	1.000	0.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.999	0.001	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.999	0.001	0.000
K82 Other diseases of gallbladder	0.988	0.012	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.982	0.018	0.000
K82.4 Cholesterolosis of gallbladder	0.965	0.035	0.000
K81 Cholecystitis	0.950	0.050	0.000
K80.4 Calculus of bile duct with cholecystitis	0.932	0.068	0.000
K83 Other diseases of biliary tract	0.924	0.076	0.000
K81.9 Cholecystitis, unspecified	0.901	0.099	0.000
K82.8 Other specified diseases of gallbladder	0.859	0.141	0.000
K83.8 Other specified diseases of biliary tract	0.833	0.167	0.000
K81.0 Acute cholecystitis	0.826	0.174	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.779	0.221	0.000
K82.9 Disease of gallbladder, unspecified	0.778	0.222	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.777	0.223	0.000
K85 Acute pancreatitis	0.774	0.226	0.000
K83.0 Cholangitis	0.765	0.235	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.761	0.239	0.000
O36 Maternal care for other known or suspected foetal problems	0.745	0.255	0.000
O00-O08 Pregnancy with abortive outcome	0.736	0.264	0.000
K82.1 Hydrops of gallbladder	0.726	0.274	0.000
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.716	0.284	0.000
O20 Haemorrhage in early pregnancy	0.715	0.285	0.000
O04 Medical abortion	0.714	0.286	0.000
K82.3 Fistula of gallbladder	0.708	0.291	0.000
K82.2 Perforation of gallbladder	0.708	0.291	0.000
K82.0 Obstruction of gallbladder	0.708	0.291	0.000
O36.8 Maternal care for other specified foetal problems	0.708	0.292	0.000
K80.8 Other cholelithiasis	0.700	0.300	0.000
O47 False labour	0.696	0.304	0.000
O04.9 Complete or unspecified, without complication	0.693	0.307	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.690	0.310	0.000
K81.8 Other cholecystitis	0.681	0.319	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.677	0.323	0.000
K83.1 Obstruction of bile duct	0.671	0.329	0.000
O44 Placenta praevia	0.665	0.335	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.663	0.337	0.000
K83.9 Disease of biliary tract, unspecified	0.662	0.337	0.000
K83.5 Biliary cyst	0.662	0.337	0.000
K83.4 Spasm of sphincter of Oddi	0.662	0.337	0.000
K83.3 Fistula of bile duct	0.662	0.337	0.000
K83.2 Perforation of bile duct	0.662	0.337	0.000
O80-O84 Delivery	0.651	0.349	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.645	0.355	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.642	0.358	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.637	0.363	0.000
O47.9 False labour, unspecified	0.631	0.369	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.629	0.371	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.628	0.372	0.000
O20.0 Threatened abortion	0.628	0.372	0.000
O24 Diabetes mellitus in pregnancy	0.628	0.372	0.000
O80 Single spontaneous delivery	0.600	0.400	0.000
O03 Spontaneous abortion	0.598	0.402	0.000
O43 Placental disorders	0.598	0.402	0.000
O36.4 Maternal care for intra-uterine death	0.597	0.403	0.000
O40 Polyhydramnios	0.595	0.405	0.000
O48 Prolonged pregnancy	0.589	0.411	0.000
K85.1 Biliary acute pancreatitis	0.587	0.413	0.000
K85.9 Acute pancreatitis, unspecified	0.585	0.415	0.000
O36.9 Maternal care for foetal problem, unspecified	0.585	0.415	0.000
O85-O92 Complications predominantly related to the puerperium	0.580	0.420	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.579	0.421	0.000
K86 Other diseases of pancreas	0.576	0.424	0.000
O44.1 Placenta praevia with haemorrhage	0.566	0.434	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.560	0.440	0.000
O45 Premature separation of placenta [abruptio placentae]	0.559	0.441	0.000
O41 Other disorders of amniotic fluid and membranes	0.559	0.441	0.000
O33 Maternal care for known or suspected disproportion	0.559	0.441	0.000
O31 Complications specific to multiple gestation	0.559	0.441	0.000
K85.8 Other acute pancreatitis	0.555	0.445	0.000
K85.3 Drug-induced acute pancreatitis	0.555	0.445	0.000
K85.2 Alcohol-induced acute pancreatitis	0.555	0.445	0.000
K85.0 Idiopathic acute pancreatitis	0.555	0.445	0.000
O36.6 Maternal care for excessive foetal growth	0.551	0.449	0.000
O26.9 Pregnancy-related condition, unspecified	0.551	0.449	0.000
O32.1 Maternal care for breech presentation	0.551	0.449	0.000
O23 Infections of genito-urinary tract in pregnancy	0.547	0.453	0.000
O29 Complications of anaesthesia during pregnancy	0.546	0.454	0.000
O28 Abnormal findings on antenatal screening of mother	0.546	0.454	0.000
O22 Venous complications in pregnancy	0.546	0.454	0.000
O21 Excessive vomiting in pregnancy	0.546	0.454	0.000
O25 Malnutrition in pregnancy	0.546	0.454	0.000
K81.1 Chronic cholecystitis	0.543	0.457	0.000
O80.9 Single spontaneous delivery, unspecified	0.542	0.458	0.000
O26.2 Pregnancy care of habitual aborter	0.537	0.463	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.534	0.466	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.534	0.466	0.000
O36.2 Maternal care for hydrops foetalis	0.534	0.466	0.000
O36.1 Maternal care for other isoimmunisation	0.534	0.466	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.534	0.466	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.534	0.466	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.532	0.468	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.528	0.472	0.000
O07 Failed attempted abortion	0.528	0.472	0.000
O06 Unspecified abortion	0.528	0.472	0.000
O05 Other abortion	0.528	0.472	0.000
O01 Hydatidiform mole	0.528	0.472	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.526	0.474	0.000
E11.9 Without complications	0.525	0.475	0.000
O46.9 Antepartum haemorrhage, unspecified	0.522	0.478	0.000
S60-S69 Injuries to the wrist and hand	0.522	0.478	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.518	0.482	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.518	0.482	0.000
O03.4 Incomplete, without complication	0.516	0.484	0.000
O34.4 Maternal care for other abnormalities of cervix	0.515	0.485	0.000
O47.0 False labour before 37 completed weeks of gestation	0.514	0.485	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.513	0.486	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.513	0.486	0.000
O20.8 Other haemorrhage in early pregnancy	0.512	0.487	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.512	0.488	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.512	0.488	0.000
O04.7 Complete or unspecified, complicated by embolism	0.512	0.488	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.512	0.488	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.512	0.488	0.000
O04.4 Incomplete, without complication	0.512	0.488	0.000
O04.3 Incomplete, with other and unspecified complications	0.512	0.488	0.000
O04.2 Incomplete, complicated by embolism	0.512	0.488	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.512	0.488	0.000
# Top node	0.512	0.488	0.000
Chapter XI Diseases of the digestive system	0.511	0.489	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.510	0.490	0.000
O26.8 Other specified pregnancy-related conditions	0.508	0.492	0.000
E10-E14 Diabetes mellitus	0.502	0.498	0.000
E11 Non-insulin-dependent diabetes mellitus	0.501	0.499	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.499	0.501	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.495	0.505	0.000
O97 Death from sequelae of direct obstetric causes	0.495	0.505	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.495	0.505	0.000
O95 Obstetric death of unspecified cause	0.495	0.505	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.495	0.505	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.494	0.506	0.000
S64 Injury of nerves at wrist and hand level	0.492	0.508	0.000
O80.0 Spontaneous vertex delivery	0.491	0.509	0.000
K70-K77 Diseases of liver	0.490	0.510	0.000
Chapter VII Diseases of the eye and adnexa	0.486	0.514	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.485	0.515	0.000
O26.5 Maternal hypotension syndrome	0.485	0.515	0.000
O26.4 Herpes gestationis	0.485	0.515	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.485	0.515	0.000
O26.1 Low weight gain in pregnancy	0.485	0.515	0.000
O26.0 Excessive weight gain in pregnancy	0.485	0.515	0.000
O36.5 Maternal care for poor foetal growth	0.481	0.519	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.479	0.521	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.478	0.522	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.475	0.525	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.475	0.525	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.475	0.525	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.475	0.525	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.475	0.525	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.475	0.525	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.475	0.525	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.475	0.525	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.475	0.525	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.471	0.529	0.000
O00 Ectopic pregnancy	0.468	0.532	0.000
O84 Multiple delivery	0.467	0.533	0.000
O83 Other assisted single delivery	0.467	0.533	0.000
O81 Single delivery by forceps and vacuum extractor	0.467	0.533	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.467	0.533	0.000
O43.1 Malformation of placenta	0.464	0.536	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.463	0.537	0.000
O32.8 Maternal care for other malpresentation of foetus	0.463	0.537	0.000
O32.6 Maternal care for compound presentation	0.463	0.537	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.463	0.537	0.000
O32.4 Maternal care for high head at term	0.463	0.537	0.000
O32.3 Maternal care for face, brow and chin presentation	0.463	0.537	0.000
O32.2 Maternal care for transverse and oblique lie	0.463	0.537	0.000
O32.0 Maternal care for unstable lie	0.461	0.539	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.460	0.539	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.460	0.539	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.460	0.539	0.000
O34.6 Maternal care for abnormality of vagina	0.460	0.539	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.460	0.539	0.000
O34.3 Maternal care for cervical incompetence	0.460	0.539	0.000
O34.0 Maternal care for congenital malformation of uterus	0.460	0.539	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.458	0.542	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.453	0.547	0.000
O46.8 Other antepartum haemorrhage	0.451	0.549	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.451	0.549	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.450	0.550	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.450	0.550	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.450	0.550	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.450	0.550	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.450	0.550	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.450	0.550	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.450	0.550	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.450	0.550	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.450	0.550	0.000
O34.1 Maternal care for tumour of corpus uteri	0.447	0.553	0.000
S80-S89 Injuries to the knee and lower leg	0.445	0.555	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.442	0.558	0.000
E14 Unspecified diabetes mellitus	0.441	0.559	0.000
O30 Multiple gestation	0.439	0.560	0.000
S64.4 Injury of digital nerve of other finger	0.439	0.561	0.000
O86 Other puerperal infections	0.439	0.561	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.438	0.562	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.438	0.562	0.000
S62 Fracture at wrist and hand level	0.438	0.562	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.437	0.563	0.000
O43.8 Other placental disorders	0.435	0.565	0.000
S60 Superficial injury of wrist and hand	0.435	0.565	0.000
K65-K67 Diseases of peritoneum	0.434	0.566	0.000
K75 Other inflammatory liver diseases	0.432	0.568	0.000
O80.8 Other single spontaneous delivery	0.430	0.570	0.000
O80.1 Spontaneous breech delivery	0.430	0.570	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.429	0.571	0.000
O03.7 Complete or unspecified, complicated by embolism	0.429	0.571	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.429	0.571	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.429	0.571	0.000
O03.3 Incomplete, with other and unspecified complications	0.429	0.571	0.000
O03.2 Incomplete, complicated by embolism	0.429	0.571	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.429	0.571	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.429	0.571	0.000
O43.9 Placental disorder, unspecified	0.429	0.571	0.000
O43.2 Morbidly adherent placenta	0.429	0.571	0.000
O43.0 Placental transfusion syndromes	0.429	0.571	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.429	0.571	0.000
K86.9 Disease of pancreas, unspecified	0.428	0.571	0.000
K86.3 Pseudocyst of pancreas	0.428	0.572	0.000
O02 Other abnormal products of conception	0.418	0.582	0.000
K76 Other diseases of liver	0.417	0.583	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.417	0.583	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.416	0.584	0.000
O91 Infections of breast associated with childbirth	0.416	0.584	0.000
O90 Complications of the puerperium, not elsewhere classified	0.416	0.584	0.000
O89 Complications of anaesthesia during the puerperium	0.416	0.584	0.000
O88 Obstetric embolism	0.416	0.584	0.000
O87 Venous complications in the puerperium	0.416	0.584	0.000
O85 Puerperal sepsis	0.416	0.584	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.416	0.584	0.000
S90-S99 Injuries to the ankle and foot	0.416	0.584	0.000
S50-S59 Injuries to the elbow and forearm	0.415	0.585	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.413	0.587	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.411	0.589	0.000
E10 Insulin-dependent diabetes mellitus	0.410	0.590	0.000
K73 Chronic hepatitis, not elsewhere classified	0.407	0.593	0.000
E14.9 Without complications	0.407	0.593	0.000
Chapter VI Diseases of the nervous system	0.406	0.594	0.000
S61 Open wound of wrist and hand	0.405	0.595	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.404	0.596	0.000
H10-H13 Disorders of conjunctiva	0.403	0.597	0.000
T79-T79 Certain early complications of trauma	0.401	0.599	0.000
O31.8 Other complications specific to multiple gestation	0.400	0.599	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.400	0.599	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.400	0.599	0.000
O31.0 Papyraceous foetus	0.400	0.599	0.000
O33.9 Maternal care for disproportion, unspecified	0.400	0.599	0.000
O33.8 Maternal care for disproportion of other origin	0.400	0.599	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.400	0.599	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.400	0.599	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.400	0.599	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.400	0.599	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.400	0.599	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.400	0.599	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.400	0.599	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.400	0.599	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.400	0.599	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.400	0.599	0.000
O41.1 Infection of amniotic sac and membranes	0.400	0.599	0.000
O41.0 Oligohydramnios	0.400	0.599	0.000
O45.9 Premature separation of placenta, unspecified	0.400	0.599	0.000
O45.8 Other premature separation of placenta	0.400	0.599	0.000
O45.0 Premature separation of placenta with coagulation defect	0.400	0.599	0.000
S70-S79 Injuries to the hip and thigh	0.400	0.600	0.000
K86.1 Other chronic pancreatitis	0.397	0.603	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.396	0.604	0.000
O03.9 Complete or unspecified, without complication	0.396	0.604	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.395	0.605	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.395	0.605	0.000
H25-H28 Disorders of lens	0.394	0.606	0.000
S81 Open wound of lower leg	0.394	0.606	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.393	0.607	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.392	0.608	0.000
O23.5 Infections of the genital tract in pregnancy	0.392	0.608	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.392	0.608	0.000
O23.2 Infections of urethra in pregnancy	0.392	0.608	0.000
O23.1 Infections of bladder in pregnancy	0.392	0.608	0.000
O23.0 Infections of kidney in pregnancy	0.392	0.608	0.000
O21.9 Vomiting of pregnancy, unspecified	0.391	0.608	0.000
O21.8 Other vomiting complicating pregnancy	0.391	0.608	0.000
O21.2 Late vomiting of pregnancy	0.391	0.608	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.391	0.608	0.000
O21.0 Mild hyperemesis gravidarum	0.391	0.608	0.000
O22.9 Venous complication in pregnancy, unspecified	0.391	0.608	0.000
O22.8 Other venous complications in pregnancy	0.391	0.608	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.391	0.608	0.000
O22.4 Haemorrhoids in pregnancy	0.391	0.608	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.391	0.608	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.391	0.608	0.000
O22.1 Genital varices in pregnancy	0.391	0.608	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.391	0.608	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.391	0.608	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.391	0.608	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.391	0.608	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.391	0.608	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.391	0.608	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.391	0.608	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.391	0.608	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.391	0.608	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.391	0.608	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.391	0.608	0.000
O29.6 Failed or difficult intubation during pregnancy	0.391	0.608	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.391	0.608	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.391	0.608	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.391	0.608	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.391	0.608	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.391	0.608	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.391	0.608	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.391	0.609	0.000
H55-H59 Other disorders of eye and adnexa	0.386	0.614	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.386	0.614	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.385	0.615	0.000
H30-H36 Disorders of choroid and retina	0.385	0.615	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.383	0.617	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.381	0.619	0.000
O01.9 Hydatidiform mole, unspecified	0.378	0.621	0.000
O01.1 Incomplete and partial hydatidiform mole	0.378	0.621	0.000
O01.0 Classical hydatidiform mole	0.378	0.621	0.000
O05.9 Complete or unspecified, without complication	0.378	0.621	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.378	0.621	0.000
O05.7 Complete or unspecified, complicated by embolism	0.378	0.621	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O05.4 Incomplete, without complication	0.378	0.621	0.000
O05.3 Incomplete, with other and unspecified complications	0.378	0.621	0.000
O05.2 Incomplete, complicated by embolism	0.378	0.621	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O06.9 Complete or unspecified, without complication	0.378	0.621	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.378	0.621	0.000
O06.7 Complete or unspecified, complicated by embolism	0.378	0.621	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O06.4 Incomplete, without complication	0.378	0.621	0.000
O06.3 Incomplete, with other and unspecified complications	0.378	0.621	0.000
O06.2 Incomplete, complicated by embolism	0.378	0.621	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.378	0.621	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.378	0.621	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.378	0.621	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O07.4 Failed medical abortion, without complication	0.378	0.621	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.378	0.621	0.000
O07.2 Failed medical abortion, complicated by embolism	0.378	0.621	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.378	0.621	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.378	0.621	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.378	0.621	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.378	0.621	0.000
K75.9 Inflammatory liver disease, unspecified	0.377	0.623	0.000
S10-S19 Injuries to the neck	0.377	0.623	0.000
G40-G47 Episodic and paroxysmal disorders	0.377	0.623	0.000
K66 Other disorders of peritoneum	0.377	0.623	0.000
T66-T78 Other and unspecified effects of external causes	0.375	0.625	0.000
S62.4 Multiple fractures of metacarpal bones	0.375	0.625	0.000
S60.2 Contusion of other parts of wrist and hand	0.375	0.625	0.000
S65 Injury of blood vessels at wrist and hand level	0.374	0.626	0.000
S20-S29 Injuries to the thorax	0.374	0.626	0.000
G40 Epilepsy	0.373	0.627	0.000
K74 Fibrosis and cirrhosis of liver	0.372	0.628	0.000
H18 Other disorders of cornea	0.372	0.628	0.000
T33-T35 Frostbite	0.371	0.629	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.371	0.629	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.371	0.629	0.000
T00-T07 Injuries involving multiple body regions	0.371	0.629	0.000
O42 Premature rupture of membranes	0.370	0.629	0.000
E10.9 Without complications	0.368	0.632	0.000
S51 Open wound of forearm	0.368	0.632	0.000
E20-E35 Disorders of other endocrine glands	0.368	0.632	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.368	0.632	0.000
E13 Other specified diabetes mellitus	0.368	0.632	0.000
H46 Optic neuritis	0.367	0.632	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.367	0.633	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.364	0.636	0.000
S67 Crushing injury of wrist and hand	0.363	0.637	0.000
K70 Alcoholic liver disease	0.361	0.639	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.361	0.639	0.000
E12 Malnutrition-related diabetes mellitus	0.360	0.640	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.359	0.640	0.000
E11.8 With unspecified complications	0.359	0.641	0.000
E11.7 With multiple complications	0.359	0.641	0.000
E11.1 With ketoacidosis	0.359	0.641	0.000
E11.0 With coma	0.359	0.641	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.359	0.641	0.000
K76.6 Portal hypertension	0.359	0.641	0.000
E11.6 With other specified complications	0.358	0.642	0.000
H25 Senile cataract	0.357	0.643	0.000
S81.0 Open wound of knee	0.356	0.644	0.000
O96.9 Death from unspecified obstetric cause	0.355	0.645	0.000
O96.1 Death from indirect obstetric cause	0.355	0.645	0.000
O96.0 Death from direct obstetric cause	0.355	0.645	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.355	0.645	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.355	0.645	0.000
O97.0 Death from sequelae of direct obstetric cause	0.355	0.645	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.355	0.645	0.000
K86.8 Other specified diseases of pancreas	0.355	0.645	0.000
E65-E68 Obesity and other hyperalimentation	0.354	0.646	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.353	0.647	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.353	0.647	0.000
S64.8 Injury of other nerves at wrist and hand level	0.353	0.647	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.353	0.647	0.000
S64.3 Injury of digital nerve of thumb	0.353	0.647	0.000
S64.1 Injury of median nerve at wrist and hand level	0.353	0.647	0.000
S68 Traumatic amputation of wrist and hand	0.352	0.648	0.000
K77 Liver disorders in diseases classified elsewhere	0.351	0.649	0.000
K71 Toxic liver disease	0.351	0.649	0.000
K75.8 Other specified inflammatory liver diseases	0.350	0.650	0.000
O00.9 Ectopic pregnancy, unspecified	0.349	0.650	0.000
G40.9 Epilepsy, unspecified	0.349	0.651	0.000
S62.2 Fracture of first metacarpal bone	0.349	0.651	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.348	0.651	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.347	0.652	0.000
H11 Other disorders of conjunctiva	0.348	0.652	0.000
S69 Other and unspecified injuries of wrist and hand	0.347	0.653	0.000
S62.5 Fracture of thumb	0.346	0.654	0.000
Chapter VIII Diseases of the ear and mastoid process	0.346	0.654	0.000
S63.6 Sprain and strain of finger(s)	0.346	0.654	0.000
T82.1 Mechanical complication of cardiac electronic device	0.345	0.655	0.000
H25.1 Senile nuclear cataract	0.344	0.656	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.344	0.656	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.344	0.656	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.344	0.656	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.344	0.656	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.344	0.656	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.344	0.656	0.000
Q50-Q56 Congenital malformations of genital organs	0.343	0.657	0.000
Q80-Q89 Other congenital malformations	0.342	0.658	0.000
S91 Open wound of ankle and foot	0.342	0.658	0.000
H34 Retinal vascular occlusions	0.340	0.660	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.339	0.661	0.000
O86.0 Infection of obstetric surgical wound	0.338	0.662	0.000
O15 Eclampsia	0.338	0.662	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.338	0.662	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.338	0.662	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.338	0.662	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.337	0.662	0.000
O00.8 Other ectopic pregnancy	0.336	0.664	0.000
O00.2 Ovarian pregnancy	0.336	0.664	0.000
O00.0 Abdominal pregnancy	0.336	0.664	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.335	0.665	0.000
O81.4 Vacuum extractor delivery	0.335	0.665	0.000
O81.3 Other and unspecified forceps delivery	0.335	0.665	0.000
O81.2 Mid-cavity forceps with rotation	0.335	0.665	0.000
O81.1 Mid-cavity forceps delivery	0.335	0.665	0.000
O81.0 Low forceps delivery	0.335	0.665	0.000
O83.9 Assisted single delivery, unspecified	0.335	0.665	0.000
O83.8 Other specified assisted single delivery	0.335	0.665	0.000
O83.4 Destructive operation for delivery	0.335	0.665	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.335	0.665	0.000
O83.2 Other manipulation-assisted delivery	0.335	0.665	0.000
O83.1 Other assisted breech delivery	0.335	0.665	0.000
O83.0 Breech extraction	0.335	0.665	0.000
O84.9 Multiple delivery, unspecified	0.335	0.665	0.000
O84.8 Other multiple delivery	0.335	0.665	0.000
O84.2 Multiple delivery, all by Caesarean section	0.335	0.665	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.335	0.665	0.000
O84.0 Multiple delivery, all spontaneous	0.335	0.665	0.000
S51.0 Open wound of elbow	0.335	0.665	0.000
E11.4 With neurological complications	0.335	0.665	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.335	0.665	0.000
Chapter XXII Codes for special purposes	0.334	0.666	0.000
Q60-Q64 Congenital malformations of the urinary system	0.334	0.666	0.000
E27 Other disorders of adrenal gland	0.334	0.666	0.000
T86 Failure and rejection of transplanted organs and tissues	0.333	0.667	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.333	0.667	0.000
E40-E46 Malnutrition	0.333	0.667	0.000
H20 Iridocyclitis	0.332	0.667	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.331	0.669	0.000
K72 Hepatic failure, not elsewhere classified	0.331	0.669	0.000
K86.2 Cyst of pancreas	0.330	0.670	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.330	0.670	0.000
K73.9 Chronic hepatitis, unspecified	0.330	0.670	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.330	0.670	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.329	0.671	0.000
O82 Single delivery by Caesarean section	0.329	0.671	0.001
H21 Other disorders of iris and ciliary body	0.328	0.671	0.000
S63.1 Dislocation finger	0.328	0.672	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations