TreeWAS – Variant ID: rs1811103

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E87 Other disorders of fluid, electrolyte and acid-base balance	0.061	0.939	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.059	0.941	0.000
E87.6 Hypokalaemia	0.056	0.944	0.000
E87.0 Hyperosmolality and hypernatraemia	0.056	0.944	0.000
E87.5 Hyperkalaemia	0.052	0.948	0.000
E87.2 Acidosis	0.050	0.950	0.000
E87.7 Fluid overload	0.048	0.952	0.000
E87.3 Alkalosis	0.047	0.953	0.000
E87.4 Mixed disorder of acid-base balance	0.044	0.956	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.037	0.963	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.033	0.967	0.000
E70-E90 Metabolic disorders	0.032	0.968	0.000
E80.4 Gilbert's syndrome	0.032	0.968	0.000
E88 Other metabolic disorders	0.028	0.972	0.000
E80.6 Other disorders of bilirubin metabolism	0.027	0.973	0.000
E85 Amyloidosis	0.026	0.974	0.000
E80.1 Porphyria cutanea tarda	0.025	0.975	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.025	0.975	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.025	0.975	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.024	0.975	0.000
E72 Other disorders of amino-acid metabolism	0.024	0.975	0.000
E70 Disorders of aromatic amino-acid metabolism	0.024	0.976	0.000
E80.5 Crigler-Najjar syndrome	0.024	0.976	0.000
E80.3 Defects of catalase and peroxydase	0.024	0.976	0.000
E80.0 Hereditary erythropoietic porphyria	0.024	0.976	0.000
E76 Disorders of glycosaminoglycan metabolism	0.023	0.976	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.023	0.976	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.023	0.976	0.000
E79 Disorders of purine and pyrimidine metabolism	0.023	0.977	0.000
E83 Disorders of mineral metabolism	0.023	0.977	0.000
E73 Lactose intolerance	0.023	0.977	0.000
E74 Other disorders of carbohydrate metabolism	0.023	0.977	0.000
E77 Disorders of glycoprotein metabolism	0.022	0.977	0.000
E88.9 Metabolic disorder, unspecified	0.022	0.978	0.000
E80.2 Other porphyria	0.022	0.978	0.000
E88.3 Tumour lysis syndrome	0.022	0.978	0.000
E85.4 Organ-limited amyloidosis	0.021	0.979	0.000
E84 Cystic fibrosis	0.021	0.979	0.000
L30.9 Dermatitis, unspecified	0.000	0.979	0.021
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.020	0.980	0.000
E75.5 Other lipid storage disorders	0.020	0.980	0.000
E88.8 Other specified metabolic disorders	0.020	0.980	0.000
E83.5 Disorders of calcium metabolism	0.020	0.980	0.000
E88.2 Lipomatosis, not elsewhere classified	0.019	0.980	0.000
E85.8 Other amyloidosis	0.019	0.981	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.019	0.981	0.000
E85.9 Amyloidosis, unspecified	0.019	0.981	0.000
E72.0 Disorders of amino-acid transport	0.019	0.981	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.019	0.981	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.019	0.981	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.019	0.981	0.000
E75.2 Other sphingolipidosis	0.019	0.981	0.000
E83.3 Disorders of phosphorus metabolism	0.018	0.981	0.000
E75.6 Lipid storage disorder, unspecified	0.018	0.982	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.018	0.982	0.000
E75.3 Sphingolipidosis, unspecified	0.018	0.982	0.000
E75.1 Other gangliosidosis	0.018	0.982	0.000
E75.0 GM2 gangliosidosis	0.018	0.982	0.000
E70.3 Albinism	0.018	0.982	0.000
E89.3 Postprocedural hypopituitarism	0.018	0.982	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.018	0.982	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.018	0.982	0.000
E72.5 Disorders of glycine metabolism	0.018	0.982	0.000
E72.4 Disorders of ornithine metabolism	0.018	0.982	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.018	0.982	0.000
E72.2 Disorders of urea cycle metabolism	0.018	0.982	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.018	0.982	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.018	0.982	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.017	0.982	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.017	0.982	0.000
E70.2 Disorders of tyrosine metabolism	0.017	0.982	0.000
E70.1 Other hyperphenylalaninaemias	0.017	0.982	0.000
E70.0 Classical phenylketonuria	0.017	0.982	0.000
E85.3 Secondary systemic amyloidosis	0.017	0.982	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.983	0.017
E71.3 Disorders of fatty-acid metabolism	0.017	0.983	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.017	0.983	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.017	0.983	0.000
E71.0 Maple-syrup-urine disease	0.017	0.983	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.017	0.983	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.017	0.983	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.017	0.983	0.000
E76.2 Other mucopolysaccharidoses	0.017	0.983	0.000
E76.1 Mucopolysaccharidosis, type II	0.017	0.983	0.000
E76.0 Mucopolysaccharidosis, type I	0.017	0.983	0.000
E74.0 Glycogen storage disease	0.017	0.983	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.017	0.983	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.017	0.983	0.000
E79.1 Lesch-Nyhan syndrome	0.017	0.983	0.000
E83.8 Other disorders of mineral metabolism	0.017	0.983	0.000
E83.2 Disorders of zinc metabolism	0.017	0.983	0.000
E83.0 Disorders of copper metabolism	0.017	0.983	0.000
E73.8 Other lactose intolerance	0.016	0.983	0.000
E73.1 Secondary lactase deficiency	0.016	0.983	0.000
E73.0 Congenital lactase deficiency	0.016	0.983	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.016	0.983	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.016	0.983	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.016	0.983	0.000
E74.2 Disorders of galactose metabolism	0.016	0.983	0.000
E74.1 Disorders of fructose metabolism	0.016	0.983	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.016	0.983	0.000
E77.1 Defects in glycoprotein degradation	0.016	0.983	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.016	0.983	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.016	0.984	0.000
E83.4 Disorders of magnesium metabolism	0.016	0.984	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.016	0.984	0.000
E73.9 Lactose intolerance, unspecified	0.016	0.984	0.000
E89.4 Postprocedural ovarian failure	0.016	0.984	0.000
L30 Other dermatitis	0.000	0.984	0.016
E74.3 Other disorders of intestinal carbohydrate absorption	0.015	0.984	0.000
E77.8 Other disorders of glycoprotein metabolism	0.015	0.984	0.000
E84.8 Cystic fibrosis with other manifestations	0.015	0.985	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.015	0.985	0.000
L30.8 Other specified dermatitis	0.000	0.985	0.015
E84.0 Cystic fibrosis with pulmonary manifestations	0.015	0.985	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.015	0.985	0.000
E89.5 Postprocedural testicular hypofunction	0.015	0.985	0.000
E89.2 Postprocedural hypoparathyroidism	0.014	0.986	0.000
E84.9 Cystic fibrosis, unspecified	0.014	0.986	0.000
F20.0 Paranoid schizophrenia	0.000	0.987	0.013
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.013	0.987	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.987	0.013
E89.1 Postprocedural hypoinsulinaemia	0.013	0.987	0.000
F20.9 Schizophrenia, unspecified	0.000	0.987	0.013
F20 Schizophrenia	0.000	0.988	0.012
L30.1 Dyshidrosis [pompholyx]	0.000	0.988	0.012
L30.3 Infective dermatitis	0.000	0.988	0.012
L30.5 Pityriasis alba	0.000	0.988	0.012
L30.2 Cutaneous autosensitisation	0.000	0.988	0.012
M54.3 Sciatica	0.000	0.988	0.012
M54.37 Sciatica (Lumbosacral region)	0.000	0.988	0.012
L30.4 Erythema intertrigo	0.000	0.989	0.011
L30.0 Nummular dermatitis	0.000	0.989	0.011
S72.00 Fracture of neck of femur (closed)	0.000	0.989	0.011
S92.00 Fracture of calcaneus (closed)	0.010	0.990	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.990	0.010
S92.0 Fracture of calcaneus	0.010	0.990	0.000
S92 Fracture of foot, except ankle	0.009	0.991	0.000
F20.6 Simple schizophrenia	0.000	0.991	0.009
F20.4 Postschizophrenic depression	0.000	0.991	0.009
F20.3 Undifferentiated schizophrenia	0.000	0.991	0.009
F20.1 Hebephrenic schizophrenia	0.000	0.991	0.009
F20.2 Catatonic schizophrenia	0.000	0.991	0.009
F20.8 Other schizophrenia	0.000	0.991	0.009
S92.3 Fracture of metatarsal bone	0.009	0.991	0.000
F20.5 Residual schizophrenia	0.000	0.991	0.009
H40.0 Glaucoma suspect	0.009	0.991	0.000
S92.30 Fracture of metatarsal bone (closed)	0.009	0.991	0.000
M54.35 Sciatica (Thoracolumbar region)	0.000	0.991	0.008
M54.34 Sciatica-Thoracic	0.000	0.991	0.008
M54.33 Sciatica-Cervicothoracic	0.000	0.991	0.008
M54.32 Sciatica-Cervical	0.000	0.991	0.008
M54.31 Sciatica-Occipit-atl-axl	0.000	0.991	0.008
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.992	0.008
S92.5 Fracture of other toe	0.008	0.992	0.000
S92.2 Fracture of other tarsal bone(s)	0.008	0.992	0.000
M54.30 Sciatica (Multiple sites in spine)	0.000	0.992	0.008
H92.0 Otalgia	0.008	0.992	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.992	0.008
S92.20 Fracture of other tarsal bone(s) (closed)	0.007	0.993	0.000
S92.01 Fracture of calcaneus (open)	0.007	0.993	0.000
S92.50 Fracture of other toe (closed)	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.007	0.993	0.000
S92.9 Fracture of foot, unspecified	0.007	0.993	0.000
S92.1 Fracture of talus	0.007	0.993	0.000
L20-L30 Dermatitis and eczema	0.000	0.993	0.007
S92.4 Fracture of great toe	0.007	0.993	0.000
S92.51 Fracture of other toe (open)	0.007	0.993	0.000
F29 Unspecified nonorganic psychosis	0.000	0.993	0.007
N47 Redundant prepuce, phimosis and paraphimosis	0.007	0.993	0.000
S92.31 Fracture of metatarsal bone (open)	0.006	0.993	0.000
F23 Acute and transient psychotic disorders	0.000	0.994	0.006
S92.7 Multiple fractures of foot	0.006	0.994	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.006	0.994	0.000
F25 Schizoaffective disorders	0.000	0.994	0.006
E78.9 Disorder of lipoprotein metabolism, unspecified	0.006	0.994	0.000
F21 Schizotypal disorder	0.000	0.994	0.006
F28 Other nonorganic psychotic disorders	0.000	0.994	0.006
F24 Induced delusional disorder	0.000	0.994	0.006
L20 Atopic dermatitis	0.000	0.994	0.006
E78.3 Hyperchylomicronaemia	0.006	0.994	0.000
E78.6 Lipoprotein deficiency	0.006	0.994	0.000
F22 Persistent delusional disorders	0.000	0.994	0.006
S92.90 Fracture of foot, unspecified (closed)	0.005	0.994	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.994	0.006
S92.40 Fracture of great toe (closed)	0.005	0.994	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.994	0.005
S92.11 Fracture of talus (open)	0.005	0.994	0.000
L23 Allergic contact dermatitis	0.000	0.995	0.005
S92.10 Fracture of talus (closed)	0.005	0.995	0.000
S92.91 Fracture of foot, unspecified (open)	0.005	0.995	0.000
L25 Unspecified contact dermatitis	0.000	0.995	0.005
E78.1 Pure hyperglyceridaemia	0.005	0.995	0.000
S72.0 Fracture of neck of femur	0.000	0.995	0.005
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
L27 Dermatitis due to substances taken internally	0.000	0.995	0.005
L24 Irritant contact dermatitis	0.000	0.995	0.005
L22 Diaper [napkin] dermatitis	0.000	0.995	0.005
L26 Exfoliative dermatitis	0.000	0.995	0.005
E78.2 Mixed hyperlipidaemia	0.005	0.995	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
E78.4 Other hyperlipidaemia	0.005	0.995	0.000
O12.1 Gestational proteinuria	0.005	0.995	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.995	0.005
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.995	0.005
E78.8 Other disorders of lipoprotein metabolism	0.005	0.995	0.000
L28.1 Prurigo nodularis	0.000	0.995	0.005
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.005	0.995	0.000
L20.9 Atopic dermatitis, unspecified	0.000	0.995	0.005
M54.36 Sciatica (Lumbar region)	0.000	0.995	0.005
L21 Seborrhoeic dermatitis	0.000	0.995	0.005
S92.71 Multiple fractures of foot (open)	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.005	0.995	0.000
S92.41 Fracture of great toe (open)	0.005	0.995	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.995	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.995	0.005
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.995	0.005
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
E89.0 Postprocedural hypothyroidism	0.005	0.995	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.995	0.005
O14.9 Preeclampsia, unspecified	0.005	0.995	0.000
C43.5 Malignant melanoma of trunk	0.000	0.995	0.005
F22.0 Delusional disorder	0.000	0.995	0.005
F25.9 Schizoaffective disorder, unspecified	0.000	0.995	0.005
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.995	0.005
F25.0 Schizoaffective disorder, manic type	0.000	0.995	0.004
L28.2 Other prurigo	0.000	0.995	0.004
F25.8 Other schizoaffective disorders	0.000	0.995	0.004
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.004	0.995	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.000	0.996	0.004
Y40.3 Macrolides	0.000	0.996	0.004
L20.0 Besnier's prurigo	0.000	0.996	0.004
F22.8 Other persistent delusional disorders	0.000	0.996	0.004
L23.0 Allergic contact dermatitis due to metals	0.000	0.996	0.004
L20.8 Other atopic dermatitis	0.000	0.996	0.004
F25.2 Schizoaffective disorder, mixed type	0.000	0.996	0.004
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.996	0.004
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.004	0.996	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.000	0.996	0.004
L27.2 Dermatitis due to ingested food	0.000	0.996	0.004
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.004	0.996	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.000	0.996	0.004
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.000	0.996	0.004
L23.4 Allergic contact dermatitis due to dyes	0.000	0.996	0.004
L23.2 Allergic contact dermatitis due to cosmetics	0.000	0.996	0.004
Z22.5 Carrier of viral hepatitis	0.000	0.996	0.004
L25.8 Unspecified contact dermatitis due to other agents	0.000	0.996	0.004
L25.5 Unspecified contact dermatitis due to plants, except food	0.000	0.996	0.004
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.000	0.996	0.004
L25.3 Unspecified contact dermatitis due to other chemical products	0.000	0.996	0.004
L25.2 Unspecified contact dermatitis due to dyes	0.000	0.996	0.004
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.000	0.996	0.004
L25.0 Unspecified contact dermatitis due to cosmetics	0.000	0.996	0.004
S72.01 Fracture of neck of femur (open)	0.000	0.996	0.004
E86 Volume depletion	0.004	0.996	0.000
L23.8 Allergic contact dermatitis due to other agents	0.000	0.996	0.004
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.996	0.004
L27.8 Dermatitis due to other substances taken internally	0.000	0.996	0.004
H92 Otalgia and effusion of ear	0.004	0.996	0.000
O15 Eclampsia	0.004	0.996	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.000	0.996	0.004
L24.8 Irritant contact dermatitis due to other agents	0.000	0.996	0.004
L24.7 Irritant contact dermatitis due to plants, except food	0.000	0.996	0.004
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.000	0.996	0.004
L24.5 Irritant contact dermatitis due to other chemical products	0.000	0.996	0.004
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.000	0.996	0.004
L24.3 Irritant contact dermatitis due to cosmetics	0.000	0.996	0.004
L24.2 Irritant contact dermatitis due to solvents	0.000	0.996	0.004
L24.1 Irritant contact dermatitis due to oils and greases	0.000	0.996	0.004
L24.0 Irritant contact dermatitis due to detergents	0.000	0.996	0.004
Z48.8 Other specified surgical follow-up care	0.000	0.996	0.004
S92.70 Multiple fractures of foot (closed)	0.004	0.996	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.996	0.004
L29 Pruritus	0.000	0.996	0.004
O14.2 HELLP syndrome	0.004	0.996	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.996	0.004
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.996	0.004
L21.8 Other seborrhoeic dermatitis	0.000	0.996	0.004
L21.1 Seborrhoeic infantile dermatitis	0.000	0.996	0.004
L21.0 Seborrhoea capitis	0.000	0.996	0.004
F22.9 Persistent delusional disorder, unspecified	0.000	0.996	0.004
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.004	0.996	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
Y95 Nosocomial condition	0.004	0.996	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.996	0.003
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
K60.2 Anal fissure, unspecified	0.003	0.997	0.000
H02.0 Entropion and trichiasis of eyelid	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
L29.8 Other pruritus	0.000	0.997	0.003
H60.1 Cellulitis of external ear	0.003	0.997	0.000
O12.0 Gestational oedema	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.003	0.997	0.000
O15.1 Eclampsia in labour	0.003	0.997	0.000
O15.0 Eclampsia in pregnancy	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
O15.2 Eclampsia in the puerperium	0.003	0.997	0.000
H60 Otitis externa	0.003	0.997	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
Z22 Carrier of infectious disease	0.000	0.997	0.003
H60.8 Other otitis externa	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.997	0.003
L29.1 Pruritus scroti	0.000	0.997	0.003
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
L28.0 Lichen simplex chronicus	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.997	0.003
L29.9 Pruritus, unspecified	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.997	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.997	0.003
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
H57.1 Ocular pain	0.000	0.997	0.003
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
Z48 Other surgical follow-up care	0.000	0.997	0.003
H57 Other disorders of eye and adnexa	0.000	0.997	0.003
H57.8 Other specified disorders of eye and adnexa	0.000	0.997	0.003
Z22.8 Carrier of other infectious diseases	0.000	0.997	0.003
H65 Nonsuppurative otitis media	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
H60.0 Abscess of external ear	0.002	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
S91.0 Open wound of ankle	0.002	0.997	0.000
S97 Crushing injury of ankle and foot	0.002	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.997	0.000
H74.0 Tympanosclerosis	0.002	0.997	0.000
Z22.9 Carrier of infectious disease, unspecified	0.000	0.997	0.002
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.997	0.002
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.997	0.002
Z22.2 Carrier of diphtheria	0.000	0.997	0.002
Z22.0 Carrier of typhoid	0.000	0.997	0.002
S91.2 Open wound of toe(s) with damage to nail	0.002	0.997	0.000
Z29 Need for other prophylactic measures	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.002	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.997	0.000
E05.5 Thyroid crisis or storm	0.000	0.998	0.002
E05.4 Thyrotoxicosis factitia	0.000	0.998	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
Y40 Systemic antibiotics	0.000	0.998	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.998	0.002
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.998	0.002
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
Z22.3 Carrier of other specified bacterial diseases	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
C60.9 Penis, unspecified	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.998	0.002
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.000	0.998	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
H00.0 Hordeolum and other deep inflammation of eyelid	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
S06 Intracranial injury	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
Z24 Need for immunisation against certain single viral diseases	0.000	0.998	0.002
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
B99 Other and unspecified infectious diseases	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
Y40.4 Tetracyclines	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.998	0.002
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.998	0.002
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
H04.8 Other disorders of lachrymal system	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
Z28 Immunisation not carried out	0.000	0.998	0.002
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.998	0.002
Z25 Need for immunisation against other single viral diseases	0.000	0.998	0.002
Z23 Need for immunisation against single bacterial diseases	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
C60.0 Prepuce	0.000	0.998	0.002
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
Z26 Need for immunisation against other single infectious diseases	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations