TreeWAS – Variant ID: rs1826411

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
S82.80 Fractures of other parts of lower leg (closed)	0.208	0.792
S82.8 Fractures of other parts of lower leg	0.204	0.796
S82 Fracture of lower leg, including ankle	0.201	0.799
S80-S89 Injuries to the knee and lower leg	0.195	0.805
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.191	0.809
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.182	0.818
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.179	0.821
S90-S99 Injuries to the ankle and foot	0.175	0.825
S82.2 Fracture of shaft of tibia	0.172	0.828
S92 Fracture of foot, except ankle	0.165	0.835
S82.0 Fracture of patella	0.164	0.836
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.164	0.836
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.162	0.838
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.160	0.840
S82.7 Multiple fractures of lower leg	0.158	0.842
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.158	0.842
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.157	0.843
S80 Superficial injury of lower leg	0.157	0.843
S82.6 Fracture of lateral malleolus	0.156	0.844
S82.4 Fracture of fibula alone	0.155	0.845
S20-S29 Injuries to the thorax	0.154	0.846
S40-S49 Injuries to the shoulder and upper arm	0.153	0.847
S82.20 Fracture of shaft of tibia (closed)	0.152	0.848
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.151	0.849
S92.0 Fracture of calcaneus	0.150	0.850
T20-T25 Burns and corrosions of external body surface, specified by site	0.149	0.851
S82.81 Fractures of other parts of lower leg (open)	0.149	0.851
S70-S79 Injuries to the hip and thigh	0.148	0.852
S10-S19 Injuries to the neck	0.147	0.853
S82.86 Maisonneuve's fracture	0.146	0.854
T36-T50 Poisoning by drugs, medicaments and biological substances	0.146	0.854
T84.3 Mechanical complication of other bone devices, implants and grafts	0.145	0.855
S30 Superficial injury of abdomen, lower back and pelvis	0.145	0.855
S82.9 Fracture of lower leg, part unspecified	0.144	0.855
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.144	0.856
T00-T07 Injuries involving multiple body regions	0.143	0.856
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.143	0.857
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.141	0.859
T87 Complications peculiar to reattachment and amputation	0.141	0.859
S88 Traumatic amputation of lower leg	0.140	0.860
S87 Crushing injury of lower leg	0.140	0.860
S86 Injury of muscle and tendon at lower leg level	0.140	0.860
S85 Injury of blood vessels at lower leg level	0.140	0.860
S84 Injury of nerves at lower leg level	0.140	0.860
S92.00 Fracture of calcaneus (closed)	0.139	0.861
T51 Toxic effect of alcohol	0.138	0.861
T15-T19 Effects of foreign body entering through natural orifice	0.138	0.861
S82.00 Fracture of patella (closed)	0.137	0.863
T33-T35 Frostbite	0.137	0.863
T26-T28 Burns and corrosions confined to eye and internal organs	0.137	0.863
T88 Other complications of surgical and medical care, not elsewhere classified	0.137	0.863
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.136	0.864
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.135	0.865
S80.1 Contusion of other and unspecified parts of lower leg	0.135	0.865
S92.1 Fracture of talus	0.134	0.866
S81 Open wound of lower leg	0.134	0.866
T82.4 Mechanical complication of vascular dialysis catheter	0.134	0.866
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.133	0.867
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.132	0.867
S82.5 Fracture of medial malleolus	0.132	0.868
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.132	0.868
T79-T79 Certain early complications of trauma	0.131	0.869
S92.2 Fracture of other tarsal bone(s)	0.131	0.869
S92.4 Fracture of great toe	0.130	0.869
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.130	0.870
S89 Other and unspecified injuries of lower leg	0.130	0.870
T85 Complications of other internal prosthetic devices, implants and grafts	0.130	0.870
S82.70 Multiple fractures of lower leg (closed)	0.127	0.872
S27 Injury of other and unspecified intrathoracic organs	0.127	0.873
S41 Open wound of shoulder and upper arm	0.126	0.873
T82.3 Mechanical complication of other vascular grafts	0.126	0.874
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.126	0.874
S91 Open wound of ankle and foot	0.126	0.874
S31 Open wound of abdomen, lower back and pelvis	0.126	0.874
T51.0 Ethanol	0.125	0.875
S99 Other and unspecified injuries of ankle and foot	0.125	0.875
S98 Traumatic amputation of ankle and foot	0.125	0.875
S97 Crushing injury of ankle and foot	0.125	0.875
S96 Injury of muscle and tendon at ankle and foot level	0.125	0.875
S95 Injury of blood vessels at ankle and foot level	0.125	0.875
S94 Injury of nerves at ankle and foot level	0.125	0.875
S22 Fracture of rib(s), sternum and thoracic spine	0.124	0.876
T80 Complications following infusion, transfusion and therapeutic injection	0.123	0.876
T86 Failure and rejection of transplanted organs and tissues	0.123	0.877
S82.60 Fracture of lateral malleolus (closed)	0.123	0.877
T84.2 Mechanical complication of internal fixation device of other bones	0.123	0.877
S82.3 Fracture of lower end of tibia	0.122	0.878
S37 Injury of urinary and pelvic organs	0.122	0.878
S80.0 Contusion of knee	0.122	0.878
S82.40 Fracture of fibula alone (closed)	0.122	0.878
T59 Toxic effect of other gases, fumes and vapours	0.121	0.879
S82.21 Fracture of shaft of tibia (open)	0.120	0.880
S49 Other and unspecified injuries of shoulder and upper arm	0.120	0.880
S30.0 Contusion of lower back and pelvis	0.120	0.880
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.120	0.880
T63 Toxic effect of contact with venomous animals	0.120	0.880
S82.1 Fracture of upper end of tibia	0.119	0.881
S92.9 Fracture of foot, unspecified	0.118	0.882
S92.7 Multiple fractures of foot	0.118	0.882
S92.5 Fracture of other toe	0.118	0.882
S90 Superficial injury of ankle and foot	0.118	0.882
S82.01 Fracture of patella (open)	0.118	0.882
T66-T78 Other and unspecified effects of external causes	0.117	0.883
T11 Other injuries of upper limb, level unspecified	0.117	0.883
T65 Toxic effect of other and unspecified substances	0.117	0.883
T62 Toxic effect of other noxious substances eaten as food	0.117	0.883
T61 Toxic effect of noxious substances eaten as seafood	0.117	0.883
T60 Toxic effect of pesticides	0.117	0.883
T57 Toxic effect of other inorganic substances	0.117	0.883
T56 Toxic effect of metals	0.117	0.883
T54 Toxic effect of corrosive substances	0.117	0.883
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.117	0.883
T52 Toxic effect of organic solvents	0.117	0.883
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.117	0.883
T58 Toxic effect of carbon monoxide	0.117	0.883
T55 Toxic effect of soaps and detergents	0.117	0.883
S40 Superficial injury of shoulder and upper arm	0.116	0.884
T85.4 Mechanical complication of breast prosthesis and implant	0.116	0.884
S30.1 Contusion of abdominal wall	0.115	0.885
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.115	0.885
S36 Injury of intra-abdominal organs	0.115	0.885
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.115	0.885
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.115	0.885
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.115	0.885
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.115	0.885
S83.3 Tear of articular cartilage of knee, current	0.114	0.886
S14 Injury of nerves and spinal cord at neck level	0.114	0.886
T20 Burn and corrosion of head and neck	0.114	0.886
S82.71 Multiple fractures of lower leg (open)	0.114	0.886
T93 Sequelae of injuries of lower limb	0.114	0.886
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.113	0.886
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.113	0.886
T82.0 Mechanical complication of heart valve prosthesis	0.113	0.886
T23 Burn and corrosion of wrist and hand	0.113	0.886
T39.0 Salicylates	0.113	0.887
S71 Open wound of hip and thigh	0.113	0.887
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.113	0.887
S72 Fracture of femur	0.113	0.887
S80.7 Multiple superficial injuries of lower leg	0.113	0.887
S92.10 Fracture of talus (closed)	0.113	0.887
T46 Poisoning by agents primarily affecting the cardiovascular system	0.112	0.888
S70 Superficial injury of hip and thigh	0.112	0.888
S82.61 Fracture of lateral malleolus (open)	0.112	0.888
S82.41 Fracture of fibula alone (open)	0.111	0.889
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.111	0.889
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.111	0.889
S26 Injury of heart	0.111	0.889
S25 Injury of blood vessels of thorax	0.111	0.889
S24 Injury of nerves and spinal cord at thorax level	0.111	0.889
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.111	0.889
S21 Open wound of thorax	0.111	0.889
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.110	0.889
T88.4 Failed or difficult intubation	0.110	0.890
S48 Traumatic amputation of shoulder and upper arm	0.110	0.890
S45 Injury of blood vessels at shoulder and upper arm level	0.110	0.890
S44 Injury of nerves at shoulder and upper arm level	0.110	0.890
S47 Crushing injury of shoulder and upper arm	0.110	0.890
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.110	0.890
T02 Fractures involving multiple body regions	0.110	0.890
T87.4 Infection of amputation stump	0.109	0.891
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.109	0.891
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.109	0.891
S50-S59 Injuries to the elbow and forearm	0.109	0.891
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.109	0.891
S12 Fracture of neck	0.108	0.892
T91 Sequelae of injuries of neck and trunk	0.108	0.892
S92.01 Fracture of calcaneus (open)	0.107	0.892
T88.5 Other complications of anaesthesia	0.107	0.892
S81.8 Open wound of other parts of lower leg	0.107	0.893
S41.1 Open wound of upper arm	0.107	0.893
S22.3 Fracture of rib	0.107	0.893
T39.1 4-Aminophenol derivatives	0.107	0.893
T25 Burn and corrosion of ankle and foot	0.107	0.893
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.107	0.893
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.107	0.893
T21 Burn and corrosion of trunk	0.107	0.893
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.107	0.893
S92.20 Fracture of other tarsal bone(s) (closed)	0.106	0.894
S78 Traumatic amputation of hip and thigh	0.106	0.894
S77 Crushing injury of hip and thigh	0.106	0.894
S76 Injury of muscle and tendon at hip and thigh level	0.106	0.894
S75 Injury of blood vessels at hip and thigh level	0.106	0.894
S74 Injury of nerves at hip and thigh level	0.106	0.894
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.106	0.894
S92.40 Fracture of great toe (closed)	0.106	0.894
S46 Injury of muscle and tendon at shoulder and upper arm level	0.105	0.894
S19 Other and unspecified injuries of neck	0.105	0.895
S17 Crushing injury of neck	0.105	0.895
S15 Injury of blood vessels at neck level	0.105	0.895
S11 Open wound of neck	0.105	0.895
S10 Superficial injury of neck	0.105	0.895
S18 Traumatic amputation at neck level	0.105	0.895
S16 Injury of muscle and tendon at neck level	0.105	0.895
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.105	0.895
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.105	0.895
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.105	0.895
T41 Poisoning by anaesthetics and therapeutic gases	0.105	0.895
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.105	0.895
T36 Poisoning by systemic antibiotics	0.105	0.895
T94 Sequelae of injuries involving multiple and unspecified body regions	0.105	0.895
T84.1 Mechanical complication of internal fixation device of bones of limb	0.105	0.895
S20 Superficial injury of thorax	0.104	0.895
S80.9 Superficial injury of lower leg, unspecified	0.104	0.896
T87.6 Other and unspecified complications of amputation stump	0.104	0.896
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.104	0.896
S30.2 Contusion of external genital organs	0.104	0.896
S82.91 Fracture of lower leg, part unspecified (open)	0.104	0.896
S82.90 Fracture of lower leg, part unspecified (closed)	0.104	0.896
T13 Other injuries of lower limb, level unspecified	0.104	0.896
T09 Other injuries of spine and trunk, level unspecified	0.104	0.896
T12.X1 Fracture of lower limb, level unspecified (open)	0.104	0.896
T12.X0 Fracture of lower limb, level unspecified (closed)	0.104	0.896
T12 Fracture of lower limb, level unspecified	0.104	0.896
T10.X1 Fracture of upper limb, level unspecified (open)	0.104	0.896
T10.X0 Fracture of upper limb, level unspecified (closed)	0.104	0.896
T10 Fracture of upper limb, level unspecified	0.104	0.896
T08.X1 Fracture of spine, level unspecified (open)	0.104	0.896
T08.X0 Fracture of spine, level unspecified (closed)	0.104	0.896
T08 Fracture of spine, level unspecified	0.104	0.896
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.103	0.896
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.103	0.896
T06 Other injuries involving multiple body regions, not elsewhere classified	0.103	0.897
T05 Traumatic amputations involving multiple body regions	0.103	0.897
T04 Crushing injuries involving multiple body regions	0.103	0.897
T03 Dislocations, sprains and strains involving multiple body regions	0.103	0.897
T01 Open wounds involving multiple body regions	0.103	0.897
T00 Superficial injuries involving multiple body regions	0.103	0.897
T07 Unspecified multiple injuries	0.103	0.897
S29 Other and unspecified injuries of thorax	0.102	0.898
T17 Foreign body in respiratory tract	0.101	0.898
S31.4 Open wound of vagina and vulva	0.101	0.899
T84.0 Mechanical complication of internal joint prosthesis	0.101	0.899
T95 Sequelae of burns, corrosions and frostbite	0.101	0.899
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.101	0.899
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.101	0.899
T87.5 Necrosis of amputation stump	0.101	0.899
T87.3 Neuroma of amputation stump	0.101	0.899
T87.2 Complications of other reattached body part	0.101	0.899
T87.1 Complications of reattached (part of) lower extremity	0.101	0.899
T87.0 Complications of reattached (part of) upper extremity	0.101	0.899
S49.8 Other specified injuries of shoulder and upper arm	0.101	0.899
S84.9 Injury of unspecified nerve at lower leg level	0.100	0.899
S84.8 Injury of other nerves at lower leg level	0.100	0.899
S84.7 Injury of multiple nerves at lower leg level	0.100	0.899
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.100	0.899
S84.1 Injury of peroneal nerve at lower leg level	0.100	0.899
S84.0 Injury of tibial nerve at lower leg level	0.100	0.899
S85.9 Injury of unspecified blood vessel at lower leg level	0.100	0.899
S85.8 Injury of other blood vessels at lower leg level	0.100	0.899
S85.7 Injury of multiple blood vessels at lower leg level	0.100	0.899
S85.5 Injury of popliteal vein	0.100	0.899
S85.4 Injury of lesser saphenous vein at lower leg level	0.100	0.899
S85.3 Injury of greater saphenous vein at lower leg level	0.100	0.899
S85.2 Injury of peroneal artery	0.100	0.899
S85.1 Injury of (anterior)(posterior) tibial artery	0.100	0.899
S85.0 Injury of popliteal artery	0.100	0.899
S86.0 Injury of Achilles tendon	0.100	0.899
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.100	0.899
S86.8 Injury of other muscles and tendons at lower leg level	0.100	0.899
S86.7 Injury of multiple muscles and tendons at lower leg level	0.100	0.899
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.100	0.899
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.100	0.899
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.100	0.899
S87.8 Crushing injury of other and unspecified parts of lower leg	0.100	0.899
S87.0 Crushing injury of knee	0.100	0.899
S88.9 Traumatic amputation of lower leg, level unspecified	0.100	0.899
S88.1 Traumatic amputation at level between knee and ankle	0.100	0.899
S88.0 Traumatic amputation at knee level	0.100	0.899
S80.8 Other superficial injuries of lower leg	0.100	0.900
T98 Sequelae of other and unspecified effects of external causes	0.100	0.900
S92.3 Fracture of metatarsal bone	0.100	0.900
T51.8 Other alcohols	0.099	0.900
T51.3 Fusel oil	0.099	0.900
T51.2 2-Propanol	0.099	0.900
T51.1 Methanol	0.099	0.900
T19 Foreign body in genito-urinary tract	0.099	0.900
T15 Foreign body on external eye	0.099	0.900
T16 Foreign body in ear	0.099	0.900
S27.0 Traumatic pneumothorax	0.099	0.900
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.099	0.901
T18 Foreign body in alimentary tract	0.099	0.901
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.099	0.901
T28 Burn and corrosion of other internal organs	0.098	0.902
T27 Burn and corrosion of respiratory tract	0.098	0.902
T26 Burn and corrosion confined to eye and adnexa	0.098	0.902
T35 Frostbite involving multiple body regions and unspecified frostbite	0.098	0.902
T34 Frostbite with tissue necrosis	0.098	0.902
T33 Superficial frostbite	0.098	0.902
T88.9 Complication of surgical and medical care, unspecified	0.098	0.902
T88.3 Malignant hyperthermia due to anaesthesis	0.098	0.902
T88.2 Shock due to anaesthesia	0.098	0.902
T88.1 Other complications following immunisation, not elsewhere classified	0.098	0.902
T88.0 Infection following immunisation	0.098	0.902
S27.3 Other injuries of lung	0.098	0.902
T11.1 Open wound of upper limb, level unspecified	0.098	0.902
S60-S69 Injuries to the wrist and hand	0.097	0.903
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.097	0.903
S92.11 Fracture of talus (open)	0.096	0.903
S81.7 Multiple open wounds of lower leg	0.096	0.904
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.096	0.904
S22.5 Flail chest	0.096	0.904
S83.7 Injury to multiple structures of knee	0.095	0.904
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.095	0.904
S83.1 Dislocation of knee	0.095	0.904
S83.0 Dislocation of patella	0.095	0.904
S79 Other and unspecified injuries of hip and thigh	0.095	0.905
S37.0 Injury of kidney	0.095	0.905
S40.0 Contusion of shoulder and upper arm	0.095	0.905
S22.30 Fracture of rib (closed)	0.095	0.905
S82.51 Fracture of medial malleolus (open)	0.095	0.905
T90 Sequelae of injuries of head	0.095	0.905
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.095	0.905
T39.4 Antirheumatics, not elsewhere classified	0.095	0.905
T39.2 Pyrazolone derivatives	0.095	0.905
T14 Injury of unspecified body region	0.094	0.905
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.095	0.905
S27.1 Traumatic haemothorax	0.094	0.906
S92.21 Fracture of other tarsal bone(s) (open)	0.094	0.906
S92.41 Fracture of great toe (open)	0.094	0.906
T32 Corrosions classified according to extent of body surface involved	0.094	0.906
T30 Burn and corrosion, body region unspecified	0.094	0.906
T29 Burns and corrosions of multiple body regions	0.094	0.906
S89.8 Other specified injuries of lower leg	0.093	0.906
S89.7 Multiple injuries of lower leg	0.093	0.906
S89.1 Other specified injuries of lower leg	0.093	0.906
S89.0 Multiple injuries of lower leg	0.093	0.906
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.093	0.906
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.093	0.907
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.093	0.907
T86.1 Kidney transplant failure and rejection	0.092	0.908
S27.9 Injury of unspecified intrathoracic organ	0.091	0.909
S27.8 Injury of other specified intrathoracic organs	0.091	0.909
S27.7 Multiple injuries of intrathoracic organs	0.091	0.909
S27.6 Injury of pleura	0.091	0.909
S27.5 Injury of thoracic trachea	0.091	0.909
S27.4 Injury of bronchus	0.091	0.909
S27.2 Traumatic heamopneumothorax	0.091	0.909
S93.1 Dislocation of toe(s)	0.091	0.909
S91.3 Open wound of other parts of foot	0.091	0.909
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.091	0.909
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.091	0.909
S41.7 Multiple open wounds of shoulder and upper arm	0.091	0.909
S41.0 Open wound of shoulder	0.091	0.909
T85.2 Mechanical complication of intraocular lens	0.091	0.909
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.091	0.909
T59.8 Other specified gases, fumes and vapours	0.091	0.909
T93.9 Sequelae of unspecified injury of lower limb	0.090	0.909
S93.4 Sprain and strain of ankle	0.090	0.909
S93.6 Sprain and strain of other and unspecified parts of foot	0.090	0.909
S93.5 Sprain and strain of toe(s)	0.090	0.909
S93.3 Dislocation of other and unspecified parts of foot	0.090	0.909
S93.2 Rupture of ligaments at ankle and foot level	0.090	0.909
S93.0 Dislocation of ankle joint	0.090	0.909
S42 Fracture of shoulder and upper arm	0.090	0.909
S91.7 Multiple open wounds of ankle and foot	0.090	0.909
S91.2 Open wound of toe(s) with damage to nail	0.090	0.909
S91.1 Open wound of toe(s) without damage to nail	0.090	0.909
S91.0 Open wound of ankle	0.090	0.909
S14.1 Other and unspecified injuries of cervical spinal cord	0.090	0.910
S31.8 Open wound of other and unspecified parts of abdomen	0.090	0.910
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.090	0.910
S31.5 Open wound of other and unspecified external genital organs	0.090	0.910
S31.3 Open wound of scrotum and testes	0.090	0.910
S31.2 Open wound of penis	0.090	0.910
S31.1 Open wound of abdominal wall	0.090	0.910
S31.0 Open wound of lower back and pelvis	0.090	0.910
S94.9 Injury of unspecified nerve at ankle and foot level	0.090	0.910
S94.8 Injury of other nerves at ankle and foot level	0.090	0.910
S94.7 Injury of multiple nerves at ankle and foot level	0.090	0.910
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.090	0.910
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.090	0.910
S94.1 Injury of medial plantar nerve	0.090	0.910
S94.0 Injury of lateral plantar nerve	0.090	0.910
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.090	0.910
S95.8 Injury of other blood vessels at ankle and foot level	0.090	0.910
S95.7 Injury of multiple blood vessels at ankle and foot level	0.090	0.910
S95.2 Injury of dorsal vein of foot	0.090	0.910
S95.1 Injury of plantar artery of foot	0.090	0.910
S95.0 Injury of dorsal artery of foot	0.090	0.910
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.090	0.910
S96.8 Injury of other muscles and tendons at ankle and foot level	0.090	0.910
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.090	0.910
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.090	0.910
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.090	0.910
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.090	0.910
S97.8 Crushing injury of other parts of ankle and foot	0.090	0.910
S97.1 Crushing injury of toe(s)	0.090	0.910
S97.0 Crushing injury of ankle	0.090	0.910
S98.4 Traumatic amputation of foot, level unspecified	0.090	0.910
S98.3 Traumatic amputation of other parts of foot	0.090	0.910
S98.2 Traumatic amputation of two or more toes	0.090	0.910
S98.1 Traumatic amputation of one toe	0.090	0.910
S98.0 Traumatic amputation of foot at ankle level	0.090	0.910
S99.9 Unspecified injury of ankle and foot	0.090	0.910
S99.8 Other specified injuries of ankle and foot	0.090	0.910
S99.7 Multiple injuries of ankle and foot	0.090	0.910
S83.6 Sprain and strain of other and unspecified parts of knee	0.090	0.910
S56 Injury of muscle and tendon at forearm level	0.090	0.910
T63.4 Venom of other arthropods	0.089	0.910
S22.9 Fracture of bony thorax, part unspecified	0.089	0.911
S22.8 Fracture of other parts of bony thorax	0.089	0.911
S22.1 Multiple fractures of thoracic spine	0.089	0.911
T80.2 Infections following infusion, transfusion and therapeutic injection	0.089	0.911
T79 Certain early complications of trauma, not elsewhere classified	0.089	0.911
S71.1 Open wound of thigh	0.089	0.911
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.089	0.911
T80.6 Other serum reactions	0.089	0.911
T80.5 Anaphylactic shock due to serum	0.089	0.911
T80.4 Rh incompatibility reaction	0.089	0.911
T80.3 ABO incompatibility reaction	0.089	0.911
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.089	0.911
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.089	0.911
S22.4 Multiple fractures of ribs	0.089	0.911
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.088	0.911
T86.4 Liver transplant failure and rejection	0.088	0.911
T86.3 Heart-lung transplant failure and rejection	0.088	0.911
T86.2 Heart transplant failure and rejection	0.088	0.911
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.089	0.911
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.089	0.911
T20.2 Burn of second degree of head and neck	0.088	0.911
T51.9 Alcohol, unspecified	0.088	0.912
T81 Complications of procedures, not elsewhere classified	0.088	0.912
S82.31 Fracture of lower end of tibia (open)	0.088	0.912
T23.2 Burn of second degree of wrist and hand	0.088	0.912
S37.9 Injury of unspecified pelvic organ	0.088	0.912
S37.8 Injury of other pelvic organs	0.088	0.912
S37.7 Injury of multiple pelvic organs	0.088	0.912
S37.6 Injury of uterus	0.088	0.912
S37.5 Injury of Fallopian tube	0.088	0.912
S37.4 Injury of ovary	0.088	0.912
S37.3 Injury of urethra	0.088	0.912
S37.2 Injury of bladder	0.088	0.912
S37.1 Injury of ureter	0.088	0.912
T46.1 Calcium-channel blockers	0.088	0.912
S72.0 Fracture of neck of femur	0.087	0.912
T93.2 Sequelae of other fractures of lower limb	0.087	0.913
T31 Burns classified according to extent of body surface involved	0.087	0.913
T93.0 Sequelae of open wound of lower limb	0.087	0.913
T59.9 Gases, fumes and vapours, unspecified	0.087	0.913
T59.7 Carbon dioxide	0.087	0.913
T59.6 Hydrogen sulphide	0.087	0.913
T59.5 Fluorine gas and hydrogen fluoride	0.087	0.913
T59.4 Chlorine gas	0.087	0.913
T59.3 Lachrymogenic gas	0.087	0.913
T59.2 Formaldehyde	0.087	0.913
T59.1 Sulphur dioxide	0.087	0.913
T59.0 Nitrogen oxides	0.087	0.913
T86.0 Bone-marrow transplant rejection	0.086	0.913
S49.7 Multiple injuries of shoulder and upper arm	0.086	0.913
S70.9 Superficial injury of hip and thigh, unspecified	0.086	0.913
S72.2 Subtrochanteric fracture	0.086	0.914
T63.9 Toxic effect of contact with unspecified venomous animal	0.086	0.914
T63.8 Toxic effect of contact with other venomous animals	0.086	0.914
T63.6 Toxic effect of contact with other marine animals	0.086	0.914
T63.5 Toxic effect of contact with fish	0.086	0.914
T63.3 Venom of spider	0.086	0.914
T63.2 Venom of scorpion	0.086	0.914
T63.1 Venom of other reptiles	0.086	0.914
T63.0 Snake venom	0.086	0.914
S81.9 Open wound of lower leg, part unspecified	0.086	0.914
S81.0 Open wound of knee	0.086	0.914
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.086	0.914
S82.11 Fracture of upper end of tibia (open)	0.085	0.914
T02.4 Fractures involving multiple regions of both upper limbs	0.085	0.914
T47.1 Other antacids and anti-gastric-secretion drugs	0.085	0.915
S92.51 Fracture of other toe (open)	0.085	0.915
S92.50 Fracture of other toe (closed)	0.085	0.915
S92.71 Multiple fractures of foot (open)	0.085	0.915
S92.70 Multiple fractures of foot (closed)	0.085	0.915
S92.91 Fracture of foot, unspecified (open)	0.085	0.915
S92.90 Fracture of foot, unspecified (closed)	0.085	0.915
S90.8 Other superficial injuries of ankle and foot	0.085	0.915
S90.7 Multiple superficial injuries of ankle and foot	0.085	0.915
S90.3 Contusion of other and unspecified parts of foot	0.085	0.915
S90.2 Contusion of toe(s) with damage to nail	0.085	0.915
S90.1 Contusion of toe(s) without damage to nail	0.085	0.915
S90.0 Contusion of ankle	0.085	0.915
T91.9 Sequelae of unspecified injury of neck and trunk	0.085	0.915
S22.2 Fracture of sternum	0.084	0.916
T75 Effects of other external causes	0.084	0.916
T74 Maltreatment syndromes	0.084	0.916
T73 Effects of other deprivation	0.084	0.916
T70 Effects of air pressure and water pressure	0.084	0.916
T69 Other effects of reduced temperature	0.084	0.916
T67 Effects of heat and light	0.084	0.916
T71 Asphyxiation	0.084	0.916
T66 Unspecified effects of radiation	0.084	0.916
T11.9 Unspecified injury of upper limb, level unspecified	0.084	0.916
T11.8 Other specified injuries of upper limb, level unspecified	0.084	0.916
T11.6 Traumatic amputation of upper limb, level unspecified	0.084	0.916
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.084	0.916
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.084	0.916
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.084	0.916
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.084	0.916
T11.0 Superficial injury of upper limb, level unspecified	0.084	0.916
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.084	0.916
S43.1 Dislocation of acromioclavicular joint	0.084	0.916
T92 Sequelae of injuries of upper limb	0.084	0.916
S89.9 Unspecified injury of lower leg	0.084	0.916
T52.9 Organic solvent, unspecified	0.084	0.916

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations