TreeWAS – Variant ID: rs186552003

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.899	0.101
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.954	0.046
R10 Abdominal and pelvic pain	0.963	0.037
R10.4 Other and unspecified abdominal pain	0.963	0.037
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.964	0.036
R11 Nausea and vomiting	0.966	0.034
E78.9 Disorder of lipoprotein metabolism, unspecified	0.967	0.033
E78.8 Other disorders of lipoprotein metabolism	0.967	0.033
E78.6 Lipoprotein deficiency	0.967	0.033
E78.4 Other hyperlipidaemia	0.967	0.033
E78.3 Hyperchylomicronaemia	0.967	0.033
E78.2 Mixed hyperlipidaemia	0.967	0.033
E78.1 Pure hyperglyceridaemia	0.967	0.033
R12 Heartburn	0.968	0.032
R10.3 Pain localised to other parts of lower abdomen	0.968	0.032
R13 Dysphagia	0.971	0.029
R10.1 Pain localised to upper abdomen	0.971	0.029
R15 Faecal incontinence	0.971	0.029
R14 Flatulence and related conditions	0.972	0.028
R17 Unspecified jaundice	0.973	0.027
R18 Ascites	0.973	0.027
R10.0 Acute abdomen	0.973	0.027
R10.2 Pelvic and perineal pain	0.973	0.027
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.974	0.026
E78.5 Hyperlipidaemia, unspecified	0.974	0.025
R19 Other symptoms and signs involving the digestive system and abdomen	0.976	0.024
E70-E90 Metabolic disorders	0.979	0.021
R19.5 Other fecal abnormalities	0.980	0.020
Z90.7 Acquired absence of genital organ(s)	0.980	0.020
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.981	0.019
R16.1 Splenomegaly, not elsewhere classified	0.981	0.019
R16.0 Hepatomegaly, not elsewhere classified	0.981	0.019
R19.4 Change in bowel habit	0.982	0.018
R19.6 Halitosis	0.983	0.017
R19.3 Abdominal rigidity	0.983	0.017
R19.2 Visible peristalsis	0.983	0.017
R19.1 Abnormal bowel sounds	0.983	0.017
Z90 Acquired absence of organs, not elsewhere classified	0.983	0.017
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.984	0.016
E87 Other disorders of fluid, electrolyte and acid-base balance	0.985	0.015
E88 Other metabolic disorders	0.985	0.015
E85 Amyloidosis	0.985	0.015
E84 Cystic fibrosis	0.985	0.015
E80 Disorders of porphyrin and bilirubin metabolism	0.985	0.015
E79 Disorders of purine and pyrimidine metabolism	0.985	0.015
E77 Disorders of glycoprotein metabolism	0.985	0.015
E76 Disorders of glycosaminoglycan metabolism	0.985	0.015
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.985	0.015
E74 Other disorders of carbohydrate metabolism	0.985	0.015
E73 Lactose intolerance	0.985	0.015
E72 Other disorders of amino-acid metabolism	0.985	0.015
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.985	0.015
E70 Disorders of aromatic amino-acid metabolism	0.985	0.015
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.985	0.015
Z90.4 Acquired absence of other parts of digestive tract	0.986	0.014
E86 Volume depletion	0.986	0.014
Z90.1 Acquired absence of breast(s)	0.986	0.014
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.987	0.013
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.987	0.013
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.987	0.013
Z90.5 Acquired absence of kidney	0.987	0.013
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.987	0.013
E83 Disorders of mineral metabolism	0.987	0.013
E87.1 Hypo-osmolality and hyponatraemia	0.987	0.013
Z90.8 Acquired absence of other organs	0.987	0.013
Z90.6 Acquired absence of other parts of urinary tract	0.987	0.013
Z90.3 Acquired absence of part of stomach	0.987	0.013
Z90.2 Acquired absence of lung [part of]	0.987	0.013
Z90.0 Acquired absence of part of head and neck	0.987	0.013
E89.0 Postprocedural hypothyroidism	0.988	0.012
E87.2 Acidosis	0.988	0.012
Z80 Family history of malignant neoplasm	0.988	0.012
Z91 Personal history of risk-factors, not elsewhere classified	0.988	0.012
R42 Dizziness and giddiness	0.988	0.012
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.988	0.012
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.988	0.012
E89.8 Other postprocedural endocrine and metabolic disorders	0.988	0.012
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.988	0.012
E89.5 Postprocedural testicular hypofunction	0.988	0.012
E89.4 Postprocedural ovarian failure	0.988	0.012
E89.3 Postprocedural hypopituitarism	0.988	0.012
E89.2 Postprocedural hypoparathyroidism	0.988	0.012
E89.1 Postprocedural hypoinsulinaemia	0.988	0.012
E87.5 Hyperkalaemia	0.988	0.011
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.988	0.012
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.988	0.012
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.989	0.011
E87.4 Mixed disorder of acid-base balance	0.989	0.011
E87.3 Alkalosis	0.989	0.011
E87.0 Hyperosmolality and hypernatraemia	0.989	0.011
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.989	0.011
E70.8 Other disorders of aromatic amino-acid metabolism	0.989	0.011
E70.3 Albinism	0.989	0.011
E70.2 Disorders of tyrosine metabolism	0.989	0.011
E70.1 Other hyperphenylalaninaemias	0.989	0.011
E70.0 Classical phenylketonuria	0.989	0.011
E71.3 Disorders of fatty-acid metabolism	0.989	0.011
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.989	0.011
E71.1 Other disorders of branched-chain amino-acid metabolism	0.989	0.011
E71.0 Maple-syrup-urine disease	0.989	0.011
E72.9 Disorder of amino-acid metabolism, unspecified	0.989	0.011
E72.8 Other specified disorders of amino-acid metabolism	0.989	0.011
E72.5 Disorders of glycine metabolism	0.989	0.011
E72.4 Disorders of ornithine metabolism	0.989	0.011
E72.3 Disorders of lysine and hydroxylysine metabolism	0.989	0.011
E72.2 Disorders of urea cycle metabolism	0.989	0.011
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.989	0.011
E72.0 Disorders of amino-acid transport	0.989	0.011
E73.9 Lactose intolerance, unspecified	0.989	0.011
E73.8 Other lactose intolerance	0.989	0.011
E73.1 Secondary lactase deficiency	0.989	0.011
E73.0 Congenital lactase deficiency	0.989	0.011
E74.9 Disorder of carbohydrate metabolism, unspecified	0.989	0.011
E74.8 Other specified disorders of carbohydrate metabolism	0.989	0.011
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.989	0.011
E74.3 Other disorders of intestinal carbohydrate absorption	0.989	0.011
E74.2 Disorders of galactose metabolism	0.989	0.011
E74.1 Disorders of fructose metabolism	0.989	0.011
E74.0 Glycogen storage disease	0.989	0.011
E75.6 Lipid storage disorder, unspecified	0.989	0.011
E75.5 Other lipid storage disorders	0.989	0.011
E75.4 Neuronal ceroid lipofuscinosis	0.989	0.011
E75.3 Sphingolipidosis, unspecified	0.989	0.011
E75.2 Other sphingolipidosis	0.989	0.011
E75.1 Other gangliosidosis	0.989	0.011
E75.0 GM2 gangliosidosis	0.989	0.011
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.989	0.011
E76.8 Other disorders of glucosaminoglycan metabolism	0.989	0.011
E76.3 Mucopolysaccharidosis, unspecified	0.989	0.011
E76.2 Other mucopolysaccharidoses	0.989	0.011
E76.1 Mucopolysaccharidosis, type II	0.989	0.011
E76.0 Mucopolysaccharidosis, type I	0.989	0.011
E77.9 Disorder of glycoprotein metabolism, unspecified	0.989	0.011
E77.8 Other disorders of glycoprotein metabolism	0.989	0.011
E77.1 Defects in glycoprotein degradation	0.989	0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.989	0.011
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.989	0.011
E79.8 Other disorders of purine and pyrimidine metabolism	0.989	0.011
E79.1 Lesch-Nyhan syndrome	0.989	0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.989	0.011
E80.7 Disorder of bilirubin metabolism, unspecified	0.989	0.011
E80.6 Other disorders of bilirubin metabolism	0.989	0.011
E80.5 Crigler-Najjar syndrome	0.989	0.011
E80.4 Gilbert's syndrome	0.989	0.011
E80.3 Defects of catalase and peroxydase	0.989	0.011
E80.2 Other porphyria	0.989	0.011
E80.1 Porphyria cutanea tarda	0.989	0.011
E80.0 Hereditary erythropoietic porphyria	0.989	0.011
E84.9 Cystic fibrosis, unspecified	0.989	0.011
E84.8 Cystic fibrosis with other manifestations	0.989	0.011
E84.1 Cystic fibrosis with intestinal manifestations	0.989	0.011
E84.0 Cystic fibrosis with pulmonary manifestations	0.989	0.011
E85.9 Amyloidosis, unspecified	0.989	0.011
E85.8 Other amyloidosis	0.989	0.011
E85.4 Organ-limited amyloidosis	0.989	0.011
E85.3 Secondary systemic amyloidosis	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.989	0.011
E88.9 Metabolic disorder, unspecified	0.989	0.011
E88.8 Other specified metabolic disorders	0.989	0.011
E88.3 Tumour lysis syndrome	0.989	0.011
E88.2 Lipomatosis, not elsewhere classified	0.989	0.011
E88.1 Lipodystrophy, not elsewhere classified	0.989	0.011
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.989	0.011
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.989	0.011
Z92 Personal history of medical treatment	0.989	0.011
Z80.3 Family history of malignant neoplasm of breast	0.989	0.011
Z98 Other postsurgical states	0.989	0.011
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.989	0.011
Z80.0 Family history of malignant neoplasm of digestive organs	0.989	0.011
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.989	0.010
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.990	0.010
Z96 Presence of other functional implants	0.990	0.010
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.990	0.010
E87.7 Fluid overload	0.990	0.010
Z93 Artificial opening status	0.990	0.010
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.990	0.010
Z91.5 Personal history of self-harm	0.990	0.010
Z94 Transplanted organ and tissue status	0.990	0.010
Z89 Acquired absence of limb	0.990	0.010
Z84 Family history of other conditions	0.990	0.010
Z81 Family history of mental and behavioural disorders	0.990	0.010
R47-R49 Symptoms and signs involving speech and voice	0.990	0.010
Z83 Family history of other specific disorders	0.990	0.010
Z96.6 Presence of orthopaedic joint implants	0.990	0.009
E83.9 Disorder of mineral metabolism, unspecified	0.991	0.009
E83.8 Other disorders of mineral metabolism	0.991	0.009
E83.3 Disorders of phosphorus metabolism	0.991	0.009
E83.2 Disorders of zinc metabolism	0.991	0.009
E83.1 Disorders of iron metabolism	0.991	0.009
E83.0 Disorders of copper metabolism	0.991	0.009
R95-R99 Ill-defined and unknown causes of mortality	0.991	0.009
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.991	0.009
Z80.4 Family history of malignant neoplasm of genital organs	0.991	0.009
Z98.0 Intestinal bypass and anastomosis status	0.991	0.009
R79 Other abnormal findings of blood chemistry	0.991	0.009
Z92.6 Personal history of chemotherapy for neoplastic disease	0.991	0.009
Z80.9 Family history of malignant neoplasm, unspecified	0.991	0.009
Z80.8 Family history of malignant neoplasm of other organs or systems	0.991	0.009
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.991	0.009
Z80.6 Family history of leukaemia	0.991	0.009
Z80.5 Family history of malignant neoplasm of urinary tract	0.991	0.009
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.991	0.009
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.991	0.009
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.991	0.009
Z85 Personal history of malignant neoplasm	0.991	0.009
R26 Abnormalities of gait and mobility	0.991	0.009
E87.6 Hypokalaemia	0.991	0.009
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.991	0.009
Z91.7 Personal history of female genital mutilation	0.991	0.009
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.991	0.009
Z91.3 Personal history of unhealthy sleep-wake schedule	0.991	0.009
Z91.2 Personal history of poor personal hygiene	0.991	0.009
Z92.3 Personal history of irradiation	0.991	0.009
R87 Abnormal findings in specimens from female genital organs	0.991	0.009
Z97 Presence of other devices	0.991	0.009
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.991	0.009
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.991	0.009
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.991	0.009
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.991	0.009
Z82.2 Family history of deafness and hearing loss	0.991	0.009
Z82.1 Family history of blindness and visual loss	0.991	0.009
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.991	0.009
R94 Abnormal results of function studies	0.991	0.009
R21 Rash and other nonspecific skin eruption	0.991	0.009
R46 Symptoms and signs involving appearance and behaviour	0.991	0.008
R45 Symptoms and signs involving emotional state	0.991	0.008
R44 Other symptoms and signs involving general sensations and perceptions	0.991	0.008
R43 Disturbances of smell and taste	0.991	0.008
Chapter IV Endocrine, nutritional and metabolic diseases	0.991	0.009
Z96.0 Presence of urogenital implants	0.991	0.009
Z82.3 Family history of stroke	0.991	0.008
E83.5 Disorders of calcium metabolism	0.992	0.008
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.992	0.008
R26.8 Other and unspecified abnormalities of gait and mobility	0.992	0.008
R91 Abnormal findings on diagnostic imaging of lung	0.992	0.008
Z91.6 Personal history of other physical trauma	0.992	0.008
R79.8 Other specified abnormal findings of blood chemistry	0.992	0.008
Z86.4 Personal history of psychoactive substance abuse	0.992	0.008
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.992	0.008
Z92.2 Personal history of long-term (current) use of other medicaments	0.992	0.008
Z86 Personal history of certain other diseases	0.992	0.008
E83.4 Disorders of magnesium metabolism	0.992	0.008
Z92.9 Personal history of medical treatment, unspecified	0.992	0.008
Z92.8 Personal history of other medical treatment	0.992	0.008
Z92.5 Personal history of rehabilitation measures	0.992	0.008
Z92.0 Personal history of contraception	0.992	0.008
Z88.1 Personal history of allergy to other antibiotic agents	0.992	0.008
Z98.8 Other specified postsurgical states	0.992	0.008
Z98.2 Presence of cerebrospinal fluid drainage device	0.992	0.008
R78 Findings of drugs and other substances, not normally found in blood	0.992	0.008
R77 Other abnormalities of plasma proteins	0.992	0.008
R76 Other abnormal immunological findings in serum	0.992	0.008
R74 Abnormal serum enzyme levels	0.992	0.008
R73 Elevated blood glucose level	0.992	0.008
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.992	0.008
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.992	0.008
R72 Abnormality of white blood cells, not elsewhere classified	0.992	0.008
R71 Abnormality of red blood cells	0.992	0.008
Z93.3 Colostomy status	0.992	0.008
R90 Abnormal findings on diagnostic imaging of central nervous system	0.992	0.008
R92 Abnormal findings on diagnostic imaging of breast	0.992	0.008
R89 Abnormal findings in specimens from other organs, systems and tissues	0.992	0.008
R86 Abnormal findings in specimens from male genital organs	0.992	0.008
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.992	0.008
R84 Abnormal findings in specimens from respiratory organs and thorax	0.992	0.008
R83 Abnormal findings in cerebrospinal fluid	0.992	0.008
Z96.9 Presence of functional implant, unspecified	0.992	0.008
Z96.7 Presence of other bone and tendon implants	0.992	0.008
Z96.5 Presence of tooth-root and mandibular implants	0.992	0.008
Z96.4 Presence of endocrine implants	0.992	0.008
Z96.3 Presence of artificial larynx	0.992	0.008
Z96.2 Presence of otological and audiological implants	0.992	0.008
R94.5 Abnormal results of liver function studies	0.992	0.008
R87.6 Abnormal cytological findings	0.992	0.008
R40 Somnolence, stupor and coma	0.992	0.007
R27 Other lack of coordination	0.992	0.007
R25 Abnormal involuntary movements	0.992	0.007
R93 Abnormal findings on diagnostic imaging of other body structures	0.992	0.007
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.992	0.008
R49 Voice disturbances	0.992	0.007
Z92.1 Personal history of long-term (current) use of anticoagulants	0.992	0.007
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.993	0.007
Z93.9 Artificial opening status, unspecified	0.993	0.007
Z93.8 Other artificial opening status	0.993	0.007
Z93.6 Other artificial openings of urinary tract status	0.993	0.007
Z93.5 Cystostomy status	0.993	0.007
Z93.4 Other artificial openings of gastro-intestinal tract status	0.993	0.007
Z93.1 Gastrostomy status	0.993	0.007
Z93.0 Tracheostomy status	0.993	0.007
E10-E14 Diabetes mellitus	0.993	0.007
R23 Other skin changes	0.993	0.007
Z81.8 Family history of other mental and behavioural disorders	0.993	0.007
Z81.4 Family history of other substance abuse	0.993	0.007
Z81.3 Family history of other psychoactive substance abuse	0.993	0.007
Z81.2 Family history of tobacco abuse	0.993	0.007
Z81.1 Family history of alcohol abuse	0.993	0.007
Z81.0 Family history of mental retardation	0.993	0.007
Z84.8 Family history of other specified conditions	0.993	0.007
Z84.3 Family history of consanguinity	0.993	0.007
Z84.2 Family history of other diseases of the genito-urinary system	0.993	0.007
Z84.1 Family history of disorders of the kidney and ureter	0.993	0.007
Z84.0 Family history of diseases of the skin and subcutaneous tissue	0.993	0.007
Z89.9 Acquired absence of limb, unspecified	0.993	0.007
Z89.8 Acquired absence of upper and lower limbs [any level]	0.993	0.007
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.993	0.007
Z89.6 Acquired absence of leg above knee	0.993	0.007
Z89.5 Acquired absence of leg at or below knee	0.993	0.007
Z89.4 Acquired absence of foot and ankle	0.993	0.007
Z89.3 Acquired absence of both upper limbs [any level]	0.993	0.007
Z89.2 Acquired absence of upper limb above wrist	0.993	0.007
Z89.1 Acquired absence of hand and wrist	0.993	0.007
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.993	0.007
Z94.9 Transplanted organ and tissue status, unspecified	0.993	0.007
Z94.8 Other transplanted organ and tissue status	0.993	0.007
Z94.7 Corneal transplant status	0.993	0.007
Z94.6 Bone transplant status	0.993	0.007
Z94.5 Skin transplant status	0.993	0.007
Z94.4 Liver transplant status	0.993	0.007
Z94.3 Heart and lungs transplant status	0.993	0.007
Z94.2 Lung transplant status	0.993	0.007
Z94.1 Heart transplant status	0.993	0.007
Z94.0 Kidney transplant status	0.993	0.007
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.993	0.007
Z98.1 Arthrodesis status	0.993	0.007
R47 Speech disturbances, not elsewhere classified	0.993	0.007
Z83.7 Family history of diseases of the digestive system	0.993	0.007
Z83.6 Family history of diseases of the respiratory system	0.993	0.007
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.993	0.007
Z83.3 Family history of diabetes mellitus	0.993	0.007
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.993	0.007
Z83.1 Family history of other infectious and parasitic diseases	0.993	0.007
Z83.0 Family history of human immunodeficiency virus [HIV]	0.993	0.007
Z93.2 Ileostomy status	0.993	0.007
Z83.5 Family history of eye and ear disorders	0.993	0.007
Z88.5 Personal history of allergy to narcotic agent	0.993	0.007
R41 Other symptoms and signs involving cognitive functions and awareness	0.993	0.007
R82 Other abnormal findings in urine	0.993	0.007
R81 Glycosuria	0.993	0.007
R80 Isolated proteinuria	0.993	0.007
R96 Other sudden death, cause unknown	0.993	0.007
R95 Sudden infant death syndrome	0.993	0.007
R99 Other ill-defined and unspecified causes of mortality	0.993	0.007
R98 Unattended death	0.993	0.007
Z92.4 Personal history of major surgery, not elsewhere classified	0.993	0.007
Z85.5 Personal history of malignant neoplasm of urinary tract	0.993	0.007
R20 Disturbances of skin sensation	0.993	0.007
Z88.2 Personal history of allergy to sulphonamides	0.993	0.007
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.993	0.007
R79.9 Abnormal finding of blood chemistry, unspecified	0.993	0.007
R79.0 Abnormal level of blood mineral	0.993	0.007
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.993	0.006
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.993	0.007
Z88.7 Personal history of allergy to serum and vaccine	0.993	0.007
Z88.4 Personal history of allergy to anaesthetic agent	0.993	0.007
Z88.3 Personal history of allergy to other anti-infective agents	0.993	0.007
Z85.0 Personal history of malignant neoplasm of digestive organs	0.993	0.007
Z85.9 Personal history of malignant neoplasm, unspecified	0.993	0.007
Z85.6 Personal history of leukaemia	0.993	0.007
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.993	0.007
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.993	0.007
R26.3 Immobility	0.993	0.007
R26.2 Difficulty in walking, not elsewhere classified	0.993	0.007
R26.1 Paralytic gait	0.993	0.007
R26.0 Ataxic gait	0.993	0.007
Z87 Personal history of other diseases and conditions	0.993	0.006
R87.9 Unspecified abnormal finding	0.993	0.006
R87.8 Other abnormal findings	0.993	0.006
R87.7 Abnormal histological findings	0.993	0.006
R87.5 Abnormal microbiological findings	0.993	0.006
R87.4 Abnormal immunological findings	0.993	0.006
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.993	0.006
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.993	0.006
R87.1 Abnormal level of hormones	0.993	0.006
R87.0 Abnormal level of enzymes	0.993	0.006
Z97.5 Presence of (intra-uterine) contraceptive device	0.993	0.006
Z97.4 Presence of external hearing-aid	0.993	0.006
Z97.3 Presence of spectacles and contact lenses	0.993	0.006
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.993	0.006
Z97.1 Presence of artificial limb (complete)(partial)	0.993	0.006
Z97.0 Presence of artificial eye	0.993	0.006
R94.8 Abnormal results of function studies of other organs and systems	0.993	0.006
R94.7 Abnormal results of other endocrine function studies	0.993	0.006
R94.6 Abnormal results of thyroid function studies	0.993	0.006
R94.4 Abnormal results of kidney function studies	0.993	0.006
R94.2 Abnormal results of pulmonary function studies	0.993	0.006
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.993	0.006
R94.0 Abnormal results of function studies of central nervous system	0.993	0.006
R43.8 Other and unspecified disturbances of smell and taste	0.994	0.006
R43.2 Parageusia	0.994	0.006
R43.1 Parosmia	0.994	0.006
R43.0 Anosmia	0.994	0.006
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.994	0.006
R44.3 Hallucinations, unspecified	0.994	0.006
R44.2 Other hallucinations	0.994	0.006
R44.1 Visual hallucinations	0.994	0.006
R44.0 Auditory hallucinations	0.994	0.006
R45.8 Other symptoms and signs involving emotional state	0.994	0.006
R45.7 State of emotional shock and stress, unspecified	0.994	0.006
R45.6 Physical violence	0.994	0.006
R45.5 Hostility	0.994	0.006
R45.4 Irritability and anger	0.994	0.006
R45.3 Demoralisation and apathy	0.994	0.006
R45.2 Unhappiness	0.994	0.006
R45.1 Restlessness and agitation	0.994	0.006
R45.0 Nervousness	0.994	0.006
R46.8 Other symptoms and signs involving appearance and behaviour	0.994	0.006
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.994	0.006
R46.6 Undue concern and preoccupation with stressful events	0.994	0.006
R46.5 Suspiciousness and marked evasiveness	0.994	0.006
R46.4 Slowness and poor responsiveness	0.994	0.006
R46.3 Overactivity	0.994	0.006
R46.2 Strange and inexplicable behaviour	0.994	0.006
R46.1 Bizarre personal appearance	0.994	0.006
R46.0 Very low level of personal hygiene	0.994	0.006
E40-E46 Malnutrition	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.994	0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.994	0.006
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.994	0.006
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.994	0.006
E50-E64 Other nutritional deficiencies	0.994	0.006
R94.3 Abnormal results of cardiovascular function studies	0.994	0.006
Z96.1 Presence of intraocular lens	0.994	0.006
Z96.8 Presence of other specified functional implants	0.994	0.006
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.994	0.006
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.994	0.006
E11 Non-insulin-dependent diabetes mellitus	0.994	0.006
Z95 Presence of cardiac and vascular implants and grafts	0.994	0.006
E14 Unspecified diabetes mellitus	0.994	0.006
R49.0 Dysphonia	0.994	0.006
R70.1 Abnormal plasma viscosity	0.994	0.006
R70.0 Elevated erythrocyte sedimentation rate	0.994	0.006
R73.9 Hyperglycaemia, unspecified	0.994	0.006
R73.0 Abnormal glucose tolerance test	0.994	0.006
R74.9 Abnormal level of unspecified serum enzyme	0.994	0.006
R74.8 Abnormal levels of other serum enzymes	0.994	0.006
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.994	0.006
R76.9 Abnormal immunological finding in serum, unspecified	0.994	0.006
R76.8 Other specified abnormal immunological findings in serum	0.994	0.006
R76.2 False-positive serological test for syphilis	0.994	0.006
R76.1 Abnormal reaction to tuberculin test	0.994	0.006
R76.0 Raised antibody titer	0.994	0.006
R77.9 Abnormality of plasma protein, unspecified	0.994	0.006
R77.8 Other specified abnormalities of plasma proteins	0.994	0.006
R77.2 Abnormality of alphafetoprotein	0.994	0.006
R77.1 Abnormality of globulin	0.994	0.006
R77.0 Abnormality of albumin	0.994	0.006
R78.9 Finding of unspecified substance, not normally found in blood	0.994	0.006
R78.8 Finding of other specified substances, not normally found in blood	0.994	0.006
R78.7 Finding of abnormal level of heavy metals in blood	0.994	0.006
R78.6 Finding of steroid agent in blood	0.994	0.006
R78.5 Finding of psychotropic drug in blood	0.994	0.006
R78.4 Finding of other drugs of addictive potential in blood	0.994	0.006
R78.3 Finding of hallucinogen in blood	0.994	0.006
R78.2 Finding of cocaine in blood	0.994	0.006
R78.1 Finding of opiate drug in blood	0.994	0.006
R78.0 Finding of alcohol in blood	0.994	0.006
Z87.4 Personal history of diseases of the genito-urinary system	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.994	0.006
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.994	0.006
R90.0 Intracranial space-occupying lesion	0.994	0.006
Z86.0 Personal history of other neoplasms	0.994	0.006
R83.9 Unspecified abnormal finding	0.994	0.006
R83.8 Other abnormal findings	0.994	0.006
R83.7 Abnormal histological findings	0.994	0.006
R83.6 Abnormal cytological findings	0.994	0.006
R83.5 Abnormal microbiological findings	0.994	0.006
R83.4 Abnormal immunological findings	0.994	0.006
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.994	0.006
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.994	0.006
R83.1 Abnormal level of hormones	0.994	0.006
R83.0 Abnormal level of enzymes	0.994	0.006
R84.9 Unspecified abnormal finding	0.994	0.006
R84.8 Other abnormal findings	0.994	0.006
R84.7 Abnormal histological findings	0.994	0.006
R84.6 Abnormal cytological findings	0.994	0.006
R84.5 Abnormal microbiological findings	0.994	0.006
R84.4 Abnormal immunological findings	0.994	0.006
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.994	0.006
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.994	0.006
R84.1 Abnormal level of hormones	0.994	0.006
R84.0 Abnormal level of enzymes	0.994	0.006
R85.9 Unspecified abnormal finding	0.994	0.006
R85.8 Other abnormal findings	0.994	0.006
R85.7 Abnormal histological findings	0.994	0.006
R85.6 Abnormal cytological findings	0.994	0.006
R85.5 Abnormal microbiological findings	0.994	0.006
R85.4 Abnormal immunological findings	0.994	0.006
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.994	0.006
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.994	0.006
R85.1 Abnormal level of hormones	0.994	0.006
R85.0 Abnormal level of enzymes	0.994	0.006
R86.9 Unspecified abnormal finding	0.994	0.006
R86.8 Other abnormal findings	0.994	0.006
R86.7 Abnormal histological findings	0.994	0.006
R86.6 Abnormal cytological findings	0.994	0.006
R86.5 Abnormal microbiological findings	0.994	0.006
R86.4 Abnormal immunological findings	0.994	0.006
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations