TreeWAS – Variant ID: rs1873283

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.976	0.024
I63 Cerebral infarction	0.015	0.985	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.015	0.985	0.000
I67.1 Cerebral aneurysm, nonruptured	0.015	0.985	0.000
I63.9 Cerebral infarction, unspecified	0.015	0.985	0.000
I67 Other cerebrovascular diseases	0.015	0.985	0.000
I67.8 Other specified cerebrovascular diseases	0.014	0.986	0.000
I60-I69 Cerebrovascular diseases	0.014	0.986	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.013	0.987	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.012	0.988	0.000
I60 Subarachnoid haemorrhage	0.012	0.988	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.011	0.989	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.011	0.989	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.011	0.989	0.000
I67.9 Cerebrovascular disease, unspecified	0.011	0.989	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.011	0.989	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.011	0.989	0.000
I67.5 Moyamoya disease	0.011	0.989	0.000
I67.4 Hypertensive encephalopathy	0.011	0.989	0.000
I67.3 Progressive vascular leukoencephalopathy	0.011	0.989	0.000
I60.8 Other subarachnoid haemorrhage	0.011	0.989	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.010	0.990	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.010	0.990	0.000
I61 Intracerebral haemorrhage	0.010	0.990	0.000
I63.8 Other cerebral infarction	0.010	0.990	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.010	0.990	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.010	0.990	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.010	0.990	0.000
I69 Sequelae of cerebrovascular disease	0.010	0.990	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.010	0.990	0.000
I67.2 Cerebral atherosclerosis	0.009	0.991	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.009	0.991	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.009	0.991	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.009	0.991	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.009	0.991	0.000
I61.8 Other intracerebral haemorrhage	0.009	0.991	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.008	0.991	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.008	0.991	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.008	0.991	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.008	0.991	0.000
I62 Other nontraumatic intracranial haemorrhage	0.008	0.992	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.008	0.992	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.008	0.992	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.008	0.992	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.008	0.992	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.008	0.992	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.008	0.992	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.008	0.992	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.008	0.992	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.008	0.992	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.008	0.992	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.008	0.992	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.008	0.992	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.008	0.992	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I68.0 Cerebral amyloid angiopathy	0.008	0.992	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.007	0.992	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.007	0.992	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.007	0.992	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.007	0.992	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.007	0.993	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.007	0.993	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.007	0.993	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.006	0.994	0.000
I62.1 Nontraumatic extradural haemorrhage	0.006	0.994	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.006	0.994	0.000
I69.3 Sequelae of cerebral infarction	0.006	0.994	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.005	0.994	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.005	0.994	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.005	0.994	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.005	0.994	0.000
I65.1 Occlusion and stenosis of basilar artery	0.005	0.994	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.005	0.994	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.005	0.995	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.005	0.995	0.000
K83.1 Obstruction of bile duct	0.005	0.995	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.005	0.995	0.000
G20 Parkinson's disease	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
Z03.1 Observation for suspected malignant neoplasm	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.997	0.003
H54.7 Unspecified visual loss	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
H54 Blindness and low vision	0.000	0.997	0.003
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.997	0.003
H54.9 Unspecified visual impairment (binocular)	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
J44 Other chronic obstructive pulmonary disease	0.003	0.997	0.000
G20-G26 Extrapyramidal and movement disorders	0.003	0.997	0.000
B07 Viral warts	0.003	0.997	0.000
D35.1 Parathyroid gland	0.000	0.997	0.003
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
I51.7 Cardiomegaly	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.002
H54.5 Low vision, one eye	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.002
H54.2 Low vision, both eyes	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
G24 Dystonia	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.002	0.998	0.000
D35.2 Pituitary gland	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
G24.3 Spasmodic torticollis	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
K51 Ulcerative colitis	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.002	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
K51.8 Other ulcerative colitis	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
G24.0 Drug-induced dystonia	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
K83.5 Biliary cyst	0.002	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
D11.0 Parotid gland	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.002	0.998	0.000
G21.9 Secondary Parkinsonism, unspecified	0.002	0.998	0.000
G21.8 Other secondary Parkinsonism	0.002	0.998	0.000
G21.4 Vascular parkinsonism	0.002	0.998	0.000
G21.3 Postencephalitic Parkinsonism	0.002	0.998	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.002	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.002	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.002	0.998	0.000
G23.2 Striatonigral degeneration	0.002	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.002	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.002	0.998	0.000
K51.5 Mucosal proctocolitis	0.002	0.998	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
K51.9 Ulcerative colitis, unspecified	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M65.34 Trigger finger-Hand	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
Z50.0 Cardiac rehabilitation	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
K51.2 Ulcerative (chronic) proctitis	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.001	0.998	0.000
Q61.5 Medullary cystic kidney	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.001	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
T38.7 Androgens and anabolic congeners	0.000	0.998	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.001
T38.5 Other oestrogens and progestogens	0.000	0.998	0.001
T38.4 Oral contraceptives	0.000	0.998	0.001
T38.2 Antithyroid drugs	0.000	0.998	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
M24 Other specific joint derangements	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.001
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
T42.4 Benzodiazepines	0.000	0.998	0.002
J46 Status asthmaticus	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
Q64 Other congenital malformations of urinary system	0.001	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.001
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
Q63.0 Accessory kidney	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.001
T44.0 Anticholinesterase agents	0.000	0.998	0.001
Q63 Other congenital malformations of kidney	0.001	0.998	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.001	0.998	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.001
M24.16 Other articular cartilage disorders (Lower leg)	0.001	0.998	0.000
M24.2 Disorder of ligament	0.001	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.001
D35.9 Endocrine gland, unspecified	0.000	0.999	0.001
D35.8 Pluriglandular involvement	0.000	0.999	0.001
D35.7 Other specified endocrine glands	0.000	0.999	0.001
D35.6 Aortic body and other paraganglia	0.000	0.999	0.001
D35.5 Carotid body	0.000	0.999	0.001
D35.4 Pineal gland	0.000	0.999	0.001
D35.3 Craniopharyngeal duct	0.000	0.999	0.001
J93.8 Other pneumothorax	0.000	0.999	0.001
J93.1 Other spontaneous pneumothorax	0.000	0.999	0.001
J93.0 Spontaneous tension pneumothorax	0.000	0.999	0.001
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.999	0.001
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.4 Tetracyclines	0.000	0.999	0.001
T36.3 Macrolides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T36.0 Penicillins	0.000	0.999	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
T37.5 Antiviral drugs	0.000	0.999	0.001
T37.4 Anthelminthics	0.000	0.999	0.001
T37.3 Other antiprotozoal drugs	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
T37.1 Antimycobacterial drugs	0.000	0.999	0.001
T37.0 Sulphonamides	0.000	0.999	0.001
T41.5 Therapeutic gases	0.000	0.999	0.001
T41.4 Anaesthetic, unspecified	0.000	0.999	0.001
T41.3 Local anaesthetics	0.000	0.999	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.999	0.001
T41.1 Intravenous anaesthetics	0.000	0.999	0.001
T41.0 Inhaled anaesthetics	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.000	0.999	0.001
T48.4 Expectorants	0.000	0.999	0.001
T48.3 Antitussives	0.000	0.999	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
T48.0 Oxytocic drugs	0.000	0.999	0.001
T49.9 Topical agent, unspecified	0.000	0.999	0.001
T49.8 Other topical agents	0.000	0.999	0.001
T49.7 Dental drugs, topically applied	0.000	0.999	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.999	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.999	0.001
T49.2 Local astringents and local detergents	0.000	0.999	0.001
T49.1 Antipruritics	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001
D12.4 Descending colon	0.001	0.999	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.001	0.999	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.999	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.999	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.999	0.001
T45.4 Iron and its compounds	0.000	0.999	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.999	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.999	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.999	0.001
J40 Bronchitis, not specified as acute or chronic	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.999	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.999	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.999	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.999	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.999	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.999	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.999	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.999	0.000
M24.58 Contracture of joint (Other)	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.999	0.000
M24.56 Contracture of joint (Lower leg)	0.001	0.999	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.53 Contracture of joint (Forearm)	0.001	0.999	0.000
M24.52 Contracture of joint (Upper arm)	0.001	0.999	0.000
M24.51 Contracture of joint (Shoulder region)	0.001	0.999	0.000
M24.50 Contracture of joint (Multiple sites)	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
M24.9 Joint derangement, unspecified	0.001	0.999	0.000
M24.7 Protrusio acetabuli	0.001	0.999	0.000
M24.6 Ankylosis of joint	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
T47.7 Emetics	0.000	0.999	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.999	0.001
T47.5 Digestants	0.000	0.999	0.001
T47.4 Other laxatives	0.000	0.999	0.001
T47.3 Saline and osmotic laxatives	0.000	0.999	0.001
T47.2 Stimulant laxatives	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.999	0.001
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.999	0.001
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.999	0.001
I30.9 Acute pericarditis, unspecified	0.001	0.999	0.000
N93.0 Postcoital and contact bleeding	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.3 Barbiturates	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.999	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.999	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.999	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.999	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.999	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.001	0.999	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.999	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.999	0.000
Q64.0 Epispadias	0.001	0.999	0.000
U80 Agent resistant to penicillin and related antibiotics	0.001	0.999	0.000
J40-J47 Chronic lower respiratory diseases	0.001	0.999	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.999	0.000
Q63.8 Other specified congenital malformations of kidney	0.001	0.999	0.000
Q63.3 Hyperplastic and giant kidney	0.001	0.999	0.000
Q63.2 Ectopic kidney	0.001	0.999	0.000
T42.1 Iminostilbenes	0.000	0.999	0.001
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.999	0.001
M24.29 Disorder of ligament (Site unspecified)	0.001	0.999	0.000
M24.28 Disorder of ligament (Other)	0.001	0.999	0.000
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.999	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.999	0.000
M24.21 Disorder of ligament (Shoulder region)	0.001	0.999	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.999	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
K59.1 Functional diarrhoea	0.001	0.999	0.000
O34.4 Maternal care for other abnormalities of cervix	0.001	0.999	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.999	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.999	0.000
M24.14 Other articular cartilage disorders (Hand)	0.001	0.999	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.999	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.999	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.001	0.999	0.000
T45.5 Anticoagulants	0.000	0.999	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
Y65.8 Other specified misadventures during surgical and medical care	0.001	0.999	0.000
Q61.0 Congenital single renal cyst	0.001	0.999	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.999	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.999	0.001
Y52 Agents primarily affecting the cardiovascular system	0.000	0.999	0.001
M24.24 Disorder of ligament (Hand)	0.001	0.999	0.000
M79.66 Pain in limb (Lower leg)	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.999	0.001
O34 Maternal care for known or suspected abnormality of pelvic organs	0.001	0.999	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.999	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.999	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.999	0.000
M24.66 Ankylosis of joint (Lower leg)	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.999	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.999	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.999	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.999	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.999	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.999	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.999	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.999	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.999	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.999	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.999	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.999	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.999	0.001
T46.7 Peripheral vasodilators	0.000	0.999	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
T46.1 Calcium-channel blockers	0.000	0.999	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
M79.65 Pain in limb (Pelvic region and thigh)	0.001	0.999	0.000
Q60.6 Potter's syndrome	0.001	0.999	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.999	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.999	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.999	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.999	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.999	0.000
Q62.6 Malposition of ureter	0.001	0.999	0.000
Q62.5 Duplication of ureter	0.001	0.999	0.000
Q62.4 Agenesis of ureter	0.001	0.999	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.999	0.000
Q62.2 Congenital megaloureter	0.001	0.999	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.999	0.000
Q62.0 Congenital hydronephrosis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations