TreeWAS – Variant ID: rs1895320

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N28.1 Cyst of kidney, acquired	0.000	0.935	0.065
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.947	0.053
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.949	0.051
R00.0 Tachycardia, unspecified	0.046	0.954	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.956	0.044
Z85.5 Personal history of malignant neoplasm of urinary tract	0.037	0.963	0.000
N25-N29 Other disorders of kidney and ureter	0.000	0.974	0.026
R00 Abnormalities of heart beat	0.022	0.978	0.000
N26 Unspecified contracted kidney	0.000	0.978	0.022
R00.1 Bradycardia, unspecified	0.021	0.979	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.980	0.020
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.981	0.019
N27 Small kidney of unknown cause	0.000	0.981	0.019
N25 Disorders resulting from impaired renal tubular function	0.000	0.982	0.018
R00.8 Other and unspecified abnormalities of heart beat	0.015	0.985	0.000
N27.0 Small kidney, unilateral	0.000	0.986	0.014
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.000	0.986	0.014
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.000	0.986	0.014
N29.0 Late syphilis of kidney	0.000	0.986	0.014
N27.9 Small kidney, unspecified	0.000	0.986	0.014
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.000	0.987	0.013
N25.1 Nephrogenic diabetes insipidus	0.000	0.987	0.013
N25.0 Renal osteodystrophy	0.000	0.987	0.013
N27.1 Small kidney, bilateral	0.000	0.987	0.013
D11.0 Parotid gland	0.000	0.987	0.013
N25.8 Other disorders resulting from impaired renal tubular function	0.000	0.988	0.012
M11.26 Other chondrocalcinosis (Lower leg)	0.011	0.989	0.000
R00.2 Palpitations	0.009	0.991	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.992	0.008
O75.0 Maternal distress during labour and delivery	0.006	0.993	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.994	0.006
M11.2 Other chondrocalcinosis	0.006	0.994	0.000
Z36 Antenatal screening	0.000	0.994	0.006
S92.30 Fracture of metatarsal bone (closed)	0.006	0.994	0.000
D11 Benign neoplasm of major salivary glands	0.000	0.994	0.006
O75 Other complications of labour and delivery, not elsewhere classified	0.005	0.995	0.000
S92.3 Fracture of metatarsal bone	0.005	0.995	0.000
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
D03.5 Melanoma in situ of trunk	0.005	0.995	0.000
Z36.8 Other antenatal screening	0.000	0.995	0.005
E23.0 Hypopituitarism	0.000	0.995	0.005
O75.5 Delayed delivery after artificial rupture of membranes	0.005	0.995	0.000
R04.0 Epistaxis	0.005	0.995	0.000
D11.9 Major salivary gland, unspecified	0.000	0.995	0.005
S92 Fracture of foot, except ankle	0.005	0.995	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.005	0.995	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.995	0.005
M11.29 Other chondrocalcinosis (Site unspecified)	0.004	0.995	0.000
M11.28 Other chondrocalcinosis (Other)	0.004	0.995	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.004	0.995	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.004	0.995	0.000
M11.24 Other chondrocalcinosis (Hand)	0.004	0.995	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.004	0.995	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.004	0.995	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.004	0.995	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.004	0.995	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.995	0.005
S92.0 Fracture of calcaneus	0.005	0.995	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.995	0.004
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.996	0.004
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.996	0.004
O75.8 Other specified complications of labour and delivery	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.996	0.004
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
D03.4 Melanoma in situ of scalp and neck	0.004	0.996	0.000
S92.1 Fracture of talus	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
O75.9 Complication of labour and delivery, unspecified	0.004	0.996	0.000
O75.4 Other complications of obstetric surgery and procedures	0.004	0.996	0.000
O75.3 Other infection during labour	0.004	0.996	0.000
O75.1 Shock during or following labour and delivery	0.004	0.996	0.000
D03 Melanoma in situ	0.004	0.996	0.000
S92.31 Fracture of metatarsal bone (open)	0.004	0.996	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.996	0.004
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.004	0.996	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
R74.8 Abnormal levels of other serum enzymes	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.003	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.996	0.004
S92.01 Fracture of calcaneus (open)	0.003	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.996	0.003
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.997	0.003
D11.7 Other major salivary glands	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
D03.9 Melanoma in situ, unspecified	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.003
Z42.1 Follow-up care involving plastic surgery of breast	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.003	0.997	0.000
S90.3 Contusion of other and unspecified parts of foot	0.003	0.997	0.000
S90.0 Contusion of ankle	0.003	0.997	0.000
N92.3 Ovulation bleeding	0.003	0.997	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.997	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.997	0.000
M11 Other crystal arthropathies	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
E29 Testicular dysfunction	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.002	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.002
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
R10.0 Acute abdomen	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
E26 Hyperaldosteronism	0.000	0.997	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.002
E32 Diseases of thymus	0.000	0.997	0.002
E31 Polyglandular dysfunction	0.000	0.997	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.002
E28 Ovarian dysfunction	0.000	0.997	0.002
E25 Adrenogenital disorders	0.000	0.997	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.002
M77.4 Metatarsalgia	0.000	0.997	0.002
R44.2 Other hallucinations	0.002	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.997	0.000
S91.0 Open wound of ankle	0.002	0.997	0.000
E29.1 Testicular hypofunction	0.000	0.998	0.002
Z85.4 Personal history of malignant neoplasm of genital organs	0.002	0.998	0.000
E27.2 Addisonian crisis	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
E20 Hypoparathyroidism	0.000	0.998	0.002
Z85 Personal history of malignant neoplasm	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
M11.9 Crystal arthropathy, unspecified	0.002	0.998	0.000
M11.8 Other specified crystal arthropathies	0.002	0.998	0.000
M11.1 Familial chondrocalcinosis	0.002	0.998	0.000
M11.0 Hydroxyapatite deposition disease	0.002	0.998	0.000
E34 Other endocrine disorders	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
M77.49 Metatarsalgia-Site unspec	0.000	0.998	0.002
M77.48 Metatarsalgia-Other	0.000	0.998	0.002
M77.46 Metatarsalgia-Lower Leg	0.000	0.998	0.002
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.998	0.002
M77.44 Metatarsalgia-Hand	0.000	0.998	0.002
M77.43 Metatarsalgia-Forearm	0.000	0.998	0.002
M77.42 Metatarsalgia-Upper arm	0.000	0.998	0.002
M77.41 Metatarsalgia-Shldr region	0.000	0.998	0.002
M77.40 Metatarsalgia-Mult sites	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
Z85.6 Personal history of leukaemia	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
Z85.0 Personal history of malignant neoplasm of digestive organs	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.002	0.998	0.000
M11.08 Hydroxyapatite deposition disease (Other)	0.002	0.998	0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)	0.002	0.998	0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)	0.002	0.998	0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)	0.002	0.998	0.000
M11.04 Hydroxyapatite deposition disease (Hand)	0.002	0.998	0.000
M11.03 Hydroxyapatite deposition disease (Forearm)	0.002	0.998	0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)	0.002	0.998	0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)	0.002	0.998	0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)	0.002	0.998	0.000
M11.19 Familial chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.18 Familial chondrocalcinosis (Other)	0.002	0.998	0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.16 Familial chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.14 Familial chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.13 Familial chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.12 Familial chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.11 Familial chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
M11.10 Familial chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
M11.89 Other specified crystal arthropathies (Site unspecified)	0.002	0.998	0.000
M11.88 Other specified crystal arthropathies (Other)	0.002	0.998	0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.002	0.998	0.000
M11.86 Other specified crystal arthropathies (Lower leg)	0.002	0.998	0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M11.84 Other specified crystal arthropathies (Hand)	0.002	0.998	0.000
M11.83 Other specified crystal arthropathies (Forearm)	0.002	0.998	0.000
M11.82 Other specified crystal arthropathies (Upper arm)	0.002	0.998	0.000
M11.81 Other specified crystal arthropathies (Shoulder region)	0.002	0.998	0.000
M11.80 Other specified crystal arthropathies (Multiple sites)	0.002	0.998	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.002	0.998	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.002	0.998	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.002	0.998	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.002	0.998	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.002	0.998	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.002	0.998	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.002	0.998	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.002	0.998	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.000	0.998	0.002
Z90.1 Acquired absence of breast(s)	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.002	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.002	0.998	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.002	0.998	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
O43.8 Other placental disorders	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
F60.0 Paranoid personality disorder	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
Z85.02 Personal history of malignant neoplasm of stomach	0.001	0.998	0.000
E34.8 Other specified endocrine disorders	0.000	0.998	0.001
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.000	0.998	0.002
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.001
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.001
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.001
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T50.8 Diagnostic agents	0.001	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.998	0.002
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.001
O69.5 Labour and delivery complicated by vascular lesion of cord	0.001	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.001	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.001	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.001
C77.5 Intrapelvic lymph nodes	0.000	0.998	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.001	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.001	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.001	0.998	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.001	0.999	0.000
F60.7 Dependent personality disorder	0.001	0.999	0.000
F60.5 Anankastic personality disorder	0.001	0.999	0.000
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.999	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
T50.5 Appetite depressants	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.999	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.999	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.999	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.999	0.000
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
S52.20 Fracture of shaft of ulna (closed)	0.001	0.999	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.999	0.000
S82.5 Fracture of medial malleolus	0.001	0.999	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.999	0.001
O69.8 Labour and delivery complicated by other cord complications	0.001	0.999	0.000
H61.0 Perichondritis of external ear	0.000	0.999	0.001
M77.1 Lateral epicondylitis	0.000	0.999	0.001
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.001	0.999	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.999	0.001
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
T39.0 Salicylates	0.001	0.999	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.001	0.999	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
F31.9 Bipolar affective disorder, unspecified	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.999	0.001
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.001	0.999	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.999	0.001
M43.62 Torticollis-Cervical	0.001	0.999	0.000
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
Z76.8 Persons encountering health services in other specified circumstances	0.001	0.999	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.999	0.000
D23.4 Skin of scalp and neck	0.001	0.999	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.999	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
H01.0 Blepharitis	0.000	0.999	0.001
N05.9 Unspecified	0.000	0.999	0.001
N20.2 Calculus of kidney with calculus of ureter	0.000	0.999	0.001
M77 Other enthesopathies	0.000	0.999	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
M43.6 Torticollis	0.001	0.999	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.001	0.999	0.000
M24.54 Contracture of joint (Hand)	0.001	0.999	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.999	0.001
M77.18 Lateral epicondylitis-Other	0.000	0.999	0.001
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.999	0.001
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.999	0.001
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.999	0.001
M77.14 Lateral epicondylitis-Hand	0.000	0.999	0.001
M77.13 Lateral epicondylitis-Forearm	0.000	0.999	0.001
M77.11 Lateral epicondylitis-Shldr region	0.000	0.999	0.001
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.999	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
D29.1 Prostate	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.999	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.999	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.999	0.000
T42.3 Barbiturates	0.001	0.999	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.999	0.000
T42.0 Hydantoin derivatives	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
O02.0 Blighted ovum and nonhydatidiform mole	0.001	0.999	0.000
M43 Other deforming dorsopathies	0.001	0.999	0.000
R04 Haemorrhage from respiratory passages	0.001	0.999	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
F62.9 Enduring personality change, unspecified	0.001	0.999	0.000
J15.1 Pneumonia due to Pseudomonas	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.999	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.999	0.000
F61 Mixed and other personality disorders	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.000	0.999	0.001
M77.3 Calcaneal spur	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations