TreeWAS – Variant ID: rs189798510

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
M06.9 Rheumatoid arthritis, unspecified	0.807	0.193
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.805	0.195
M06 Other rheumatoid arthritis	0.805	0.195
M05-M14 Inflammatory polyarthropathies	0.779	0.221
M06.0 Seronegative rheumatoid arthritis	0.761	0.239
M05 Seropositive rheumatoid arthritis	0.746	0.254
M05.9 Seropositive rheumatoid arthritis, unspecified	0.722	0.278
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.714	0.286
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.713	0.287
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.696	0.304
M65-M68 Disorders of synovium and tendon	0.690	0.310
M80-M85 Disorders of bone density and structure	0.683	0.317
M06.3 Rheumatoid nodule	0.683	0.317
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.672	0.328
M50-M54 Other dorsopathies	0.670	0.330
M67 Other disorders of synovium and tendon	0.657	0.343
M50 Cervical disk disorders	0.656	0.344
M84 Disorders of continuity of bone	0.653	0.347
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.653	0.347
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.649	0.351
M67.8 Other specified disorders of synovium and tendon	0.631	0.369
M50.0 Cervical disk disorder with myelopathy	0.625	0.375
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.621	0.379
M14 Arthropathies in other diseases classified elsewhere	0.616	0.384
M60-M63 Disorders of muscles	0.613	0.387
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.606	0.394
M06.34 Rheumatoid nodule (Hand)	0.595	0.405
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.592	0.408
M91-M94 Chondropathies	0.589	0.411
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.588	0.412
M80 Osteoporosis with pathological fracture	0.583	0.417
M11 Other crystal arthropathies	0.582	0.418
M06.98 Rheumatoid arthritis, unspecified (Other)	0.579	0.421
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.579	0.421
M06.8 Other specified rheumatoid arthritis	0.577	0.423
M06.2 Rheumatoid bursitis	0.577	0.423
M06.1 Adult-onset Still's disease	0.577	0.423
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.576	0.424
M84.1 Nonunion of fracture [pseudarthrosis]	0.574	0.426
M65 Synovitis and tenosynovitis	0.568	0.432
M82 Osteoporosis in diseases classified elsewhere	0.565	0.435
M84.0 Malunion of fracture	0.565	0.435
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.561	0.439
M12 Other specific arthropathies	0.559	0.441
M09 Juvenile arthritis in diseases classified elsewhere	0.559	0.441
M08 Juvenile arthritis	0.559	0.441
M84.4 Pathological fracture, not elsewhere classified	0.549	0.451
M06.08 Seronegative rheumatoid arthritis (Other)	0.546	0.454
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.546	0.454
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.546	0.454
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.546	0.454
M06.04 Seronegative rheumatoid arthritis (Hand)	0.546	0.454
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.546	0.454
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.546	0.454
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.546	0.454
M62 Other disorders of muscle	0.541	0.459
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.539	0.461
M50.9 Cervical disk disorder, unspecified	0.537	0.463
M50.3 Other cervical disk degeneration	0.535	0.464
M05.8 Other seropositive rheumatoid arthritis	0.535	0.465
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.535	0.465
M05.2 Rheumatoid vasculitis	0.535	0.465
M05.1 Rheumatoid lung disease	0.535	0.465
M05.0 Felty's syndrome	0.535	0.465
M06.4 Inflammatory polyarthropathy	0.532	0.467
M65.9 Synovitis and tenosynovitis, unspecified	0.531	0.469
M66 Spontaneous rupture of synovium and tendon	0.531	0.469
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.518	0.482
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.518	0.482
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.518	0.482
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.518	0.482
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.518	0.482
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.518	0.482
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.518	0.482
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.518	0.482
M10 Gout	0.518	0.482
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.504	0.496
M84.03 Malunion of fracture (Forearm)	0.501	0.499
M67.2 Synovial hypertrophy, not elsewhere classified	0.501	0.499
M14.6 Neuropathic arthropathy	0.498	0.502
M50.1 Cervical disk disorder with radiculopathy	0.495	0.505
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.495	0.505
M07 Psoriatic and enteropathic arthropathies	0.492	0.508
M83 Adult osteomalacia	0.490	0.510
M06.39 Rheumatoid nodule (Site unspecified)	0.489	0.510
M06.38 Rheumatoid nodule (Other)	0.489	0.510
M06.37 Rheumatoid nodule (Ankle and foot)	0.489	0.510
M06.36 Rheumatoid nodule (Lower leg)	0.489	0.510
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.489	0.510
M06.33 Rheumatoid nodule (Forearm)	0.489	0.510
M06.32 Rheumatoid nodule (Upper arm)	0.489	0.510
M06.31 Rheumatoid nodule (Shoulder region)	0.489	0.510
M06.30 Rheumatoid nodule (Multiple sites)	0.489	0.510
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.486	0.514
M86-M90 Other osteopathies	0.485	0.514
M00-M03 Infectious arthropathies	0.485	0.514
M94 Other disorders of cartilage	0.484	0.516
M82.1 Osteoporosis in endocrine disorders	0.481	0.519
M85 Other disorders of bone density and structure	0.477	0.523
M67.9 Disorder of synovium and tendon, unspecified	0.471	0.529
M67.4 Ganglion	0.471	0.529
M67.3 Transient synovitis	0.471	0.529
M67.0 Short Achilles tendon (acquired)	0.471	0.529
M50.2 Other cervical disk displacement	0.470	0.530
M50.8 Other cervical disk disorders	0.470	0.530
M84.9 Disorder of continuity of bone, unspecified	0.468	0.531
M84.8 Other disorders of continuity of bone	0.468	0.531
M84.3 Stress fracture, not elsewhere classified	0.468	0.531
M84.2 Delayed union of fracture	0.468	0.531
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.468	0.532
M62.8 Other specified disorders of muscle	0.467	0.533
M80.8 Other osteoporosis with pathological fracture	0.464	0.536
M54 Dorsalgia	0.462	0.538
M67.1 Other contracture of tendon (sheath)	0.461	0.539
M80.0 Postmenopausal osteoporosis with pathological fracture	0.458	0.542
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.451	0.549
M93 Other osteochondropathies	0.450	0.550
M66.4 Spontaneous rupture of other tendons	0.448	0.552
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.446	0.554
M80.9 Unspecified osteoporosis with pathological fracture	0.446	0.554
M14.8 Arthropathies in other specified diseases classified elsewhere	0.441	0.558
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.441	0.558
M14.4 Arthropathy in amyloidosis	0.441	0.558
M14.3 Lipoid dermatoarthritis	0.441	0.558
M14.2 Diabetic arthropathy	0.441	0.558
M14.1 Crystal arthropathy in other metabolic disorders	0.441	0.558
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.441	0.558
M11.2 Other chondrocalcinosis	0.440	0.560
M63 Disorders of muscle in diseases classified elsewhere	0.439	0.560
M61 Calcification and ossification of muscle	0.439	0.560
M60 Myositis	0.439	0.560
M54.3 Sciatica	0.437	0.563
M84.48 Pathological fracture, not elsewhere classified (Other)	0.436	0.563
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.436	0.564
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.434	0.566
M80.5 Idiopathic osteoporosis with pathological fracture	0.433	0.567
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.426	0.574
M53 Other dorsopathies, not elsewhere classified	0.424	0.576
M92 Other juvenile osteochondrosis	0.422	0.577
M91 Juvenile osteochondrosis of hip and pelvis	0.422	0.577
M65.8 Other synovitis and tenosynovitis	0.422	0.578
M80.4 Drug-induced osteoporosis with pathological fracture	0.418	0.582
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.418	0.582
M80.2 Osteoporosis of disuse with pathological fracture	0.418	0.582
M11.9 Crystal arthropathy, unspecified	0.417	0.583
M11.8 Other specified crystal arthropathies	0.417	0.583
M11.1 Familial chondrocalcinosis	0.417	0.583
M11.0 Hydroxyapatite deposition disease	0.417	0.583
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.415	0.585
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.414	0.586
M06.19 Adult-onset Still's disease (Site unspecified)	0.414	0.586
M06.18 Adult-onset Still's disease (Other)	0.414	0.586
M06.17 Adult-onset Still's disease (Ankle and foot)	0.414	0.586
M06.16 Adult-onset Still's disease (Lower leg)	0.414	0.586
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.414	0.586
M06.14 Adult-onset Still's disease (Hand)	0.414	0.586
M06.13 Adult-onset Still's disease (Forearm)	0.414	0.586
M06.12 Adult-onset Still's disease (Upper arm)	0.414	0.586
M06.11 Adult-onset Still's disease (Shoulder region)	0.414	0.586
M06.10 Adult-onset Still's disease (Multiple sites)	0.414	0.586
M06.29 Rheumatoid bursitis (Site unspecified)	0.414	0.586
M06.28 Rheumatoid bursitis (Other)	0.414	0.586
M06.27 Rheumatoid bursitis (Ankle and foot)	0.414	0.586
M06.26 Rheumatoid bursitis (Lower leg)	0.414	0.586
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.414	0.586
M06.24 Rheumatoid bursitis (Hand)	0.414	0.586
M06.23 Rheumatoid bursitis (Forearm)	0.414	0.586
M06.22 Rheumatoid bursitis (Upper arm)	0.414	0.586
M06.21 Rheumatoid bursitis (Shoulder region)	0.414	0.586
M06.20 Rheumatoid bursitis (Multiple sites)	0.414	0.586
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.414	0.586
M06.88 Other specified rheumatoid arthritis (Other)	0.414	0.586
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.414	0.586
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.414	0.586
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.414	0.586
M06.84 Other specified rheumatoid arthritis (Hand)	0.414	0.586
M06.83 Other specified rheumatoid arthritis (Forearm)	0.414	0.586
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.414	0.586
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.414	0.586
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.414	0.586
M40-M43 Deforming dorsopathies	0.413	0.587
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.412	0.588
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.411	0.589
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.411	0.589
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.411	0.589
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.411	0.589
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.410	0.590
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.408	0.592
M65.2 Calcific tendinitis	0.407	0.592
M65.1 Other infective (teno)synovitis	0.407	0.592
M65.0 Abscess of tendon sheath	0.407	0.592
M89 Other disorders of bone	0.407	0.593
M82.8 Osteoporosis in other diseases classified elsewhere	0.405	0.595
M82.0 Osteoporosis in multiple myelomatosis	0.405	0.595
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.405	0.595
M84.09 Malunion of fracture (Site unspecified)	0.405	0.595
M84.08 Malunion of fracture (Other)	0.405	0.595
M84.07 Malunion of fracture (Ankle and foot)	0.405	0.595
M84.06 Malunion of fracture (Lower leg)	0.405	0.595
M84.05 Malunion of fracture (Pelvic region and thigh)	0.405	0.595
M84.04 Malunion of fracture (Hand)	0.405	0.595
M84.02 Malunion of fracture (Upper arm)	0.405	0.595
M84.01 Malunion of fracture (Shoulder region)	0.405	0.595
M84.00 Malunion of fracture (Multiple sites)	0.405	0.595
M94.9 Disorder of cartilage, unspecified	0.405	0.595
M54.39 Sciatica (Site unspecified)	0.403	0.597
M99 Biomechanical lesions, not elsewhere classified	0.402	0.597
M45-M49 Spondylopathies	0.402	0.598
M08.9 Juvenile arthritis, unspecified	0.401	0.599
M08.8 Other juvenile arthritis	0.401	0.599
M08.4 Pauciarticular juvenile arthritis	0.401	0.599
M08.3 Juvenile polyarthritis (seronegative)	0.401	0.599
M08.2 Juvenile arthritis with systemic onset	0.401	0.599
M08.1 Juvenile ankylosing spondylitis	0.401	0.599
M08.0 Juvenile rheumatoid arthritis	0.401	0.599
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.401	0.599
M09.2 Juvenile arthritis in ulcerative colitis	0.401	0.599
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.401	0.599
M09.0 Juvenile arthritis in psoriasis	0.401	0.599
M12.8 Other specific arthropathies, not elsewhere classified	0.401	0.599
M12.5 Traumatic arthropathy	0.401	0.599
M12.4 Intermittent hydrarthrosis	0.401	0.599
M12.3 Palindromic rheumatism	0.401	0.599
M12.2 Villonodular synovitis (pigmented)	0.401	0.599
M12.1 Kaschin-Beck disease	0.401	0.599
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.401	0.599
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.400	0.600
M51 Other intervertebral disk disorders	0.400	0.600
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.395	0.605
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.394	0.606
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.394	0.606
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.394	0.606
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.394	0.606
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.394	0.606
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.394	0.606
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.394	0.606
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.394	0.606
M13 Other arthritis	0.389	0.611
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.389	0.611
M62.9 Disorder of muscle, unspecified	0.388	0.612
M62.6 Muscle strain	0.388	0.612
M62.4 Contracture of muscle	0.388	0.612
M62.3 Immobility syndrome (paraplegic)	0.388	0.612
M62.2 Ischaemic infarction of muscle	0.388	0.612
M62.1 Other rupture of muscle (nontraumatic)	0.388	0.612
M62.0 Diastasis of muscle	0.388	0.612
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.388	0.612
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.386	0.614
M05.09 Felty's syndrome (Site unspecified)	0.384	0.616
M05.08 Felty's syndrome (Other)	0.384	0.616
M05.07 Felty's syndrome (Ankle and foot)	0.384	0.616
M05.06 Felty's syndrome (Lower leg)	0.384	0.616
M05.05 Felty's syndrome (Pelvic region and thigh)	0.384	0.616
M05.04 Felty's syndrome (Hand)	0.384	0.616
M05.03 Felty's syndrome (Forearm)	0.384	0.616
M05.02 Felty's syndrome (Upper arm)	0.384	0.616
M05.01 Felty's syndrome (Shoulder region)	0.384	0.616
M05.00 Felty's syndrome (Multiple sites)	0.384	0.616
M05.19 Rheumatoid lung disease (Site unspecified)	0.384	0.616
M05.18 Rheumatoid lung disease (Other)	0.384	0.616
M05.17 Rheumatoid lung disease (Ankle and foot)	0.384	0.616
M05.16 Rheumatoid lung disease (Lower leg)	0.384	0.616
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.384	0.616
M05.14 Rheumatoid lung disease (Hand)	0.384	0.616
M05.13 Rheumatoid lung disease (Forearm)	0.384	0.616
M05.12 Rheumatoid lung disease (Upper arm)	0.384	0.616
M05.11 Rheumatoid lung disease (Shoulder region)	0.384	0.616
M05.10 Rheumatoid lung disease (Multiple sites)	0.384	0.616
M05.29 Rheumatoid vasculitis (Site unspecified)	0.384	0.616
M05.28 Rheumatoid vasculitis (Other)	0.384	0.616
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.384	0.616
M05.26 Rheumatoid vasculitis (Lower leg)	0.384	0.616
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.384	0.616
M05.24 Rheumatoid vasculitis (Hand)	0.384	0.616
M05.23 Rheumatoid vasculitis (Forearm)	0.384	0.616
M05.22 Rheumatoid vasculitis (Upper arm)	0.384	0.616
M05.21 Rheumatoid vasculitis (Shoulder region)	0.384	0.616
M05.20 Rheumatoid vasculitis (Multiple sites)	0.384	0.616
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.384	0.616
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.384	0.616
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.384	0.616
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.384	0.616
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.384	0.616
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.384	0.616
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.384	0.616
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.384	0.616
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.384	0.616
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.384	0.616
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.384	0.616
M05.88 Other seropositive rheumatoid arthritis (Other)	0.384	0.616
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.384	0.616
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.384	0.616
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.384	0.616
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.384	0.616
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.384	0.616
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.384	0.616
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.384	0.616
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.384	0.616
M06.48 Inflammatory polyarthropathy (Other)	0.382	0.618
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.382	0.618
M06.46 Inflammatory polyarthropathy (Lower leg)	0.382	0.618
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.382	0.618
M06.44 Inflammatory polyarthropathy (Hand)	0.382	0.618
M06.43 Inflammatory polyarthropathy (Forearm)	0.382	0.618
M06.42 Inflammatory polyarthropathy (Upper arm)	0.382	0.618
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.382	0.618
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.382	0.618
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.381	0.619
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.381	0.619
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.381	0.619
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.381	0.619
M66.5 Spontaneous rupture of unspecified tendon	0.381	0.619
M66.3 Spontaneous rupture of flexor tendons	0.381	0.619
M66.1 Rupture of synovium	0.381	0.619
M54.36 Sciatica (Lumbar region)	0.381	0.619
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.378	0.622
M80.88 Other osteoporosis with pathological fracture (Other)	0.378	0.622
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.373	0.627
M10.4 Other secondary gout	0.371	0.629
M10.3 Gout due to impairment of renal function	0.371	0.629
M10.2 Drug-induced gout	0.371	0.629
M10.1 Lead-induced gout	0.371	0.629
M10.0 Idiopathic gout	0.371	0.629
M54.8 Other dorsalgia	0.369	0.631
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.368	0.632
M62.88 Other specified disorders of muscle (Other)	0.367	0.632
M94.8 Other specified disorders of cartilage	0.366	0.633
M62.86 Other specified disorders of muscle (Lower leg)	0.366	0.634
M66.0 Rupture of popliteal cyst	0.365	0.635
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.360	0.639
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.360	0.640
M85.0 Fibrous dysplasia (monostotic)	0.356	0.643
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.355	0.645
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.355	0.645
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.354	0.646
M95.4 Acquired deformity of chest and rib	0.353	0.647
M07.6 Other enteropathic arthropathies	0.353	0.647
M07.5 Arthropathy in ulcerative colitis	0.353	0.647
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.353	0.647
M07.2 Psoriatic spondylitis	0.353	0.647
M07.1 Arthritis mutilans	0.353	0.647
M07.0 Distal interphalangeal psoriatic arthropathy	0.353	0.647
M83.9 Adult osteomalacia, unspecified	0.351	0.648
M83.8 Other adult osteomalacia	0.351	0.648
M83.5 Other drug-induced osteomalacia in adults	0.351	0.648
M83.4 Aluminum bone disease	0.351	0.648
M83.3 Adult osteomalacia due to malnutrition	0.351	0.648
M83.2 Adult osteomalacia due to malabsorption	0.351	0.648
M83.1 Senile osteomalacia	0.351	0.648
M83.0 Puerperal osteomalacia	0.351	0.648
M54.6 Pain in thoracic spine	0.351	0.649
M93.9 Osteochondropathy, unspecified	0.349	0.650
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.348	0.652
M02 Reactive arthropathies	0.348	0.652
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.348	0.652
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.348	0.652
M94.3 Chondrolysis	0.347	0.653
M94.1 Relapsing polychondritis	0.347	0.653
M94.0 Chondrocostal junction syndrome [Tietze]	0.347	0.653
M66.2 Spontaneous rupture of extensor tendons	0.346	0.654
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.345	0.655
M82.18 Osteoporosis in endocrine disorders (Other)	0.345	0.655
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.345	0.655
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.345	0.655
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.345	0.655
M82.14 Osteoporosis in endocrine disorders (Hand)	0.345	0.655
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.345	0.655
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.345	0.655
M88 Paget's disease of bone [osteitis deformans]	0.343	0.657
M85.9 Disorder of bone density and structure, unspecified	0.342	0.658
M85.5 Aneurysmal bone cyst	0.342	0.658
M85.4 Solitary bone cyst	0.342	0.658
M85.3 Osteitis condensans	0.342	0.658
M85.2 Hyperostosis of skull	0.342	0.658
M85.1 Skeletal fluorosis	0.342	0.658
M89.9 Disorder of bone, unspecified	0.341	0.659
M11.26 Other chondrocalcinosis (Lower leg)	0.338	0.661
M67.49 Ganglion, multiple sites	0.338	0.662
M67.47 Ganglion, ankle and foot	0.338	0.662
M67.45 Ganglion, hip	0.338	0.662
M67.43 Ganglion, wrist	0.338	0.662
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.338	0.662
M65.4 Radial styloid tenosynovitis [de Quervain]	0.337	0.663
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.337	0.663
M84.29 Delayed union of fracture (Site unspecified)	0.336	0.664
M84.28 Delayed union of fracture (Other)	0.336	0.664
M84.27 Delayed union of fracture (Ankle and foot)	0.336	0.664
M84.26 Delayed union of fracture (Lower leg)	0.336	0.664
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.336	0.664
M84.24 Delayed union of fracture (Hand)	0.336	0.664
M84.23 Delayed union of fracture (Forearm)	0.336	0.664
M84.22 Delayed union of fracture (Upper arm)	0.336	0.664
M84.21 Delayed union of fracture (Shoulder region)	0.336	0.664
M84.20 Delayed union of fracture (Multiple sites)	0.336	0.664
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.336	0.664
M84.38 Stress fracture, not elsewhere classified (Other)	0.336	0.664
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.336	0.664
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.336	0.664
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.336	0.664
M84.34 Stress fracture, not elsewhere classified (Hand)	0.336	0.664
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.336	0.664
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.336	0.664
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.336	0.664
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.336	0.664
M84.89 Other disorders of continuity of bone (Site unspecified)	0.336	0.664
M84.88 Other disorders of continuity of bone (Other)	0.336	0.664
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.336	0.664
M84.86 Other disorders of continuity of bone (Lower leg)	0.336	0.664
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.336	0.664
M84.84 Other disorders of continuity of bone (Hand)	0.336	0.664
M84.83 Other disorders of continuity of bone (Forearm)	0.336	0.664
M84.82 Other disorders of continuity of bone (Upper arm)	0.336	0.664
M84.81 Other disorders of continuity of bone (Shoulder region)	0.336	0.664
M84.80 Other disorders of continuity of bone (Multiple sites)	0.336	0.664
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.336	0.664
M84.98 Disorder of continuity of bone, unspecified (Other)	0.336	0.664
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.336	0.664
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.336	0.664
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.336	0.664
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.336	0.664
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.336	0.664
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.336	0.664
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.336	0.664
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.336	0.664
M62.87 Other specified disorders of muscle (Ankle and foot)	0.335	0.665
M62.84 Other specified disorders of muscle (Hand)	0.335	0.665
M62.83 Other specified disorders of muscle (Forearm)	0.335	0.665
M62.82 Other specified disorders of muscle (Upper arm)	0.335	0.665
M62.81 Other specified disorders of muscle (Shoulder region)	0.335	0.665
M54.1 Radiculopathy	0.334	0.665
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.332	0.667
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.332	0.667
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.332	0.667
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.332	0.667
M80.84 Other osteoporosis with pathological fracture (Hand)	0.332	0.667
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.332	0.667
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.332	0.667
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.332	0.667
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.332	0.667
M85.6 Other cyst of bone	0.331	0.668
M54.0 Panniculitis affecting regions of neck and back	0.331	0.669
M94.2 Chondromalacia	0.330	0.669
M10.9 Gout, unspecified	0.330	0.670
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.328	0.672
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.328	0.672
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.328	0.672
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.328	0.672
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.328	0.672
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.328	0.672
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.328	0.672
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.328	0.672
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.328	0.672
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.326	0.674
M86 Osteomyelitis	0.325	0.674
M96.0 Pseudarthrosis after fusion or arthrodesis	0.325	0.675
M62.80 Other specified disorders of muscle (Multiple sites)	0.325	0.675
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.325	0.675
M96.8 Other postprocedural musculoskeletal disorders	0.324	0.676
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.324	0.676
M85.8 Other specified disorders of bone density and structure	0.323	0.677
M00 Pyogenic arthritis	0.322	0.677
M93.8 Other specified osteochondropathies	0.322	0.677
M93.2 Osteochondritis dissecans	0.322	0.677
M93.1 Kienbock's disease of adults	0.322	0.677
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.322	0.677
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.321	0.679
M66.48 Spontaneous rupture of other tendons (Other)	0.321	0.679
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.321	0.679
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.321	0.679
M66.44 Spontaneous rupture of other tendons (Hand)	0.321	0.679
M66.43 Spontaneous rupture of other tendons (Forearm)	0.321	0.679
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.321	0.679
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.321	0.679
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.321	0.679
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.320	0.680
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.320	0.680
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.320	0.680
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.320	0.680
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.320	0.680
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.320	0.680
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.320	0.680
M65.84 Other synovitis and tenosynovitis (Hand)	0.318	0.682
M90 Osteopathies in diseases classified elsewhere	0.317	0.683
M11.29 Other chondrocalcinosis (Site unspecified)	0.315	0.684
M11.28 Other chondrocalcinosis (Other)	0.315	0.684
M11.27 Other chondrocalcinosis (Ankle and foot)	0.315	0.684
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.315	0.684
M11.24 Other chondrocalcinosis (Hand)	0.315	0.684
M11.23 Other chondrocalcinosis (Forearm)	0.315	0.684
M11.22 Other chondrocalcinosis (Upper arm)	0.315	0.684
M11.21 Other chondrocalcinosis (Shoulder region)	0.315	0.684
M11.20 Other chondrocalcinosis (Multiple sites)	0.315	0.684
M60.9 Myositis, unspecified	0.315	0.685
M60.8 Other myositis	0.315	0.685
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.315	0.685
M60.1 Interstitial myositis	0.315	0.685
M60.0 Infective myositis	0.315	0.685
M61.9 Calcification and ossification of muscle, unspecified	0.315	0.685
M61.5 Other ossification of muscle	0.315	0.685
M61.4 Other calcification of muscle	0.315	0.685

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations